• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.32 no.2
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• pp.64-74
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• 2021

Background and Objectives This study was to investigate the voice quality and articulation effects of laryngeal massage on muscle tension dysphonia (MTD). Materials and Method A systematic review of articles published between January 2000 and December 2020 in Cochrane, PubMed, ScienceDirect, SpingerLink, ERIC, and Naver Academic was conducted. From the total of 2094 articles identified, 10 peer-reviewed articles were included in a meta-analysis. Mean effect sizes of the variables related to voice quality (jitter, shimmer, harmonic to noise ratio or noise to harmonic ratio, high-F0, low-I, cepstral peak prominence) and articulation (F1, F2, F1 slope, F2 slope) were calculated by Hedges'g. Results Meta-analysis of the selected articles showed that laryngeal massage had medium to large effects on all variables of voice quality and articulation except F0-high and F1 slope in the MTD patients. Conclusion This study provided comprehensive clinical evidence that it is highly desirable to apply laryngeal massage to MTD patients.

• Journal of the Korean Society of School Health
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• v.34 no.2
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• pp.87-97
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• 2021

Purpose: The authors used a meta-analysis approach to investigate the effects of exercise on gender-specific triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) in obese adolescents. Methods: This study is a systematic review and meta-analysis study to confirm the effect of exercise intervention according to gender for obese adolescents. PICO were obese a adolescents, exercise intervention, comparative intervention (control and general group),TG and HDL-C. Results: The group of obese male adolescents showed a statistically significant decrease of 51.72 in TG (n=175, MD=-51.72; 95% CI -52.44 to -51.00).There was a statistically significant increase of 4.44 in HDL-C (n=175, MD=4.44; 95% CI 3.79 to 5.10) in the group of obese male adolescents. Conclusion: Triglyceride and high-density lipoprotein cholesterol were analyzed to determine the effect of exercise interventions in obese adolescents according to gender differences. The results of this study can be used as basic data for the design of future exercise intervention studies, subjects, exercise methods, and intervention periods.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.17 no.1
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• pp.1-10
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• 2022

Objectives To evaluate the effectiveness of Chuna manual therapy (CMT) for postpartum hypogalactia. Methods Using nine electronic databases, we selected 13 randomized controlled trials (RCTs) that applied CMT for postpartum hypogalactia and conducted a meta-analysis. The risk of bias was assessed using the Cochrane risk of bias tool. Results Meta-analysis showed statistically significant results for CMT in terms of effective rate and breast filling degree compared to the other treatment groups (p<0.05). Conclusions Our study showed clinical evidence of CMT efficacy for postpartum hypogalactia. Further studies are required to support our findings.

• Korean Journal of Community Nutrition
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• v.28 no.3
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• pp.192-205
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• 2023

Objectives: Previous studies have evaluated the association between mercury exposure and obesity but have yielded mixed conclusions. The aim of this study was to systematically review and summarize scientific evidence regarding the association between mercury exposure and obesity in the human population. Methods: We conducted a systematic search of PubMed, Web of Science, Scopus, and Science Direct for articles related to mercury exposure and obesity. Meta-analyses of the highest and lowest categories of mercury levels were evaluated using a random effects model. Begg's test was used to detect publication bias. Results: A total of 9 articles were included. The pooled random effects odds ratio (OR) for mercury exposure and obesity of all 9 studies was 1.66 (95% confidence interval [CI]: 1.16-2.38). This positive association was evident in adults (OR: 1.61, 95% CI: 1.02-2.54) and among studies with Asian populations (OR: 2.00, 95% CI: 1.53-2.59), but not among those with North America/African populations (OR: 0.90, 95% CI: 0.50-1.65). Conclusions: The present meta-analysis identified a positive association between mercury exposure and obesity. These findings suggest that toxic environmental metals such as mercury may be an important risk factor for obesity along with dietary habits and lifestyles.

• Journal of Gastric Cancer
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• v.23 no.3
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• pp.428-450
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• 2023

This meta-analysis examined the surgical management of older patients (>80 years) with gastric cancer, who were often excluded from randomized controlled trials. We analyzed 23 retrospective cohort studies involving 18,372 patients and found that older patients had a higher in-hospital mortality rate (relative risk [RR], 3.23; 95% confidence interval [CI], 1.46-7.17; P<0.01) and more post-operative complications (RR, 1.36; 95% CI, 1.19-1.56; P<0.01) than did younger patients. However, the surgical complications were similar between the two groups. Older patients were more likely to undergo less extensive lymph node dissection and longer hospital stays. Although older patients had statistically significant post-operative medical complications, they were not deprived of surgery for gastric cancer. The comorbidities and potential risks of post-operative complications should be carefully evaluated in older patients, highlighting the importance of careful patient selection. Overall, this meta-analysis provides recommendations for the surgical management of older patients with gastric cancer. Careful patient selection and evaluation of comorbidities should be performed to minimize the risk of post-operative complications in older patients, while recognizing that they should not be deprived of surgery for gastric cancer.

• The Journal of the Korean dental association
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• v.56 no.1
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• pp.18-40
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• 2018

Meta-analysis is a statistical method that combines the results of individual studies on the same topic. This method is becoming popular, due to providing the combined result that individual studies cannot provide and giving a more precise result. Despite meta-analysis having such significance, there were few Korean guides for the use of the Review Manager (RevMan) software. This study will provide a step-by-step guide, using orthodontic mini-screw as a dental example, to help researcher carry out meta-analysis more easily and accurately.

• Information Systems Review
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• v.1 no.2
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• pp.41-54
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• 1999

지금까지 메타-몰에서의 지불처리 보안 방안을 살펴보았다. 사실상의 표준인 SET이 1인의 상인만을 대상으로 하고 있으므로, 여러 하부 몰을 거느리고 원-스톱 지불을 지원하는 메타-몰에는 그대로 적용할 수 없었다. 따라서, 메타-몰에서는 지불대표자의 개념을 도입하여 Meta-Malls Coordinator가 SET에서의 상인 역할을 하면서 Mall Operator들에 대해 주문정보를 전달하도록 하였다. 고객, Meta-Malls Coordinator, 금융기관 간에는 SET 규정을 따름으로써, 메시지의 기밀성, 인증, 무결성, 연결성을 확보하였다. 그리고, Meta-Malls Coordinator와 Mall Operator 간의 주문정보에 대한 인증과 무결성을 위하여 주문정보에 전자서명을 하도록 하였으며, 전자서명의 Refreshness를 위하여 Challenge를 주고 받을 수 있도록 주문확인과 주문통지의 두 번의 메시지 전달단계를 정의하였다. 동시에, 주문확인 메시지는 재고확인 등의 판매 가능성 여부를 확인하는 절차를 겸하도록 하였다. 본 방법론은 SET을 메타-몰에 적용하는 방안으로서 구현 되었으나, SET이외의 지불방법론에 대해서도 동일하게 적용될 수 있다. 현재 (주)메타랜드(http://www.metaland.com)가 실제 고객들을 대상으로 이러한 지불정보 보안체계를 갖는 메타-몰 구조의 전자쇼핑몰을 운영 중에 있다.

• Korean Journal of Applied Biomechanics
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• v.32 no.2
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• pp.56-68
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• 2022

Objective: The purpose of this systematic review and meta-analysis was to investigate potential effects of HRT (hormone replacement therapy) on motor functions in postmenopausal women. Method: In this meta-analysis, 19 studies that examined changes in motor functions between postmenopausal women with and without HRT intervention were qualified. We additionally conducted moderator variable analyses including: (1) motor function type, (2) hormone type, and (3) duration of HRT intervention. Results: The random effects model showed no significant overall effects (SMD = 0.199; SE = 0.115; 95% CI = -0.026~0.425; Z = 1.730; p = 0.084; I² = 93.258%). Additional three moderator variable analyses revealed no significant effect sizes indicating that specific HRT protocols did not improve different motor functions in postmenopausal women. Conclusion: These meta-analytic findings suggest that HRT had no positive effects on motor functions in postmenopausal women.

• The korean journal of orthodontics
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• v.48 no.6
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• pp.395-404
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• 2018

Objective: To date, only a few studies have investigated the relationships between genetic polymorphisms and external apical root resorption (EARR). Hence, the aim of this systematic review was to explore the relationship between different gene polymorphisms and their association with EARR. Methods: A complete literature search was conducted by two independent reviewers. The PubMed, Science Direct, and Scopus databases were searched. In addition, the bibliographies of all textbooks and relevant articles were searched manually. A meta-analysis was performed using data entered into the electronic databases until February 28, 2017. Results: On the basis of the search, we identified 17 and 7 publications for the systematic review and meta-analysis, respectively. Odds ratio (OR) was used to evaluate the association of the interleukin 1B (+3954) polymorphism and the risk of EARR. The overall OR from the studies was used to estimate the risk of EARR. However, no association was found and no publication bias was apparent for the risk of EARR in patients receiving orthodontic treatment. Conclusions: More research on the relationship between gene polymorphism and EARR is necessary to determine better specificity of possible interactions.

• The Journal of Korean Medicine
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• v.41 no.1
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• pp.93-106
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• 2020

Objectives: The aim of this review is to ascertain whether Bojungikgi-tang and its modifications is more effective than non-specific management in chronic fatigue syndrome (CFS). Methods: We collected clinical trials to investigate the effects of Bojungikgi-tang and non-specific management on general symptoms, fatigue, and sleep quality in CFS patients. The databases used for data retrieval were Pubmed, Central Cochrane, CNKI, VIP, CiNii, OASIS, RISS, and Koreamed. We performed selection/exclusion process from the found records according to prespecified criteria, and assessed the final included trials according to the Cochrane risk of bias tool. The included studies were classified on the basis of interventions in experimental group. Results: Seven randomized controlled trials (476 participants) were eligible and their results were synthesized in the meta-analysis. The synthesis showed a substantial effect of Bojungikgi-tang (relative risk 0.20 [95% CI 0.13 to 0.31], Z=7.44, P<0.00001; I²=0%) and combination of Bojungikgi-tang and Sosiho-tang (relative risk 0.15 [95% CI 0.08 to 0.28], Z=5.85, P<0.00001; I²=0%) compared with non-specific management on improvement of general symptoms. However, we could not find sufficient clinical research records to determine their effects of improvement on fatigue and sleep quality. Conclusions: Bojungikgi-tang and its modifications are more effective than non-specific management for improvement of general symptoms in CFS post-treatment.