• Title/Summary/Keyword: Meta-analyses

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No evidence on the effectiveness of oral splints for the management of temporomandibular joint dysfunction pain in both short and long-term follow-up systematic reviews and meta-analysis studies

  • Fouda, Atef Abdel Hameed
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.46 no.2
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    • pp.87-98
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    • 2020
  • The aim of this study was to determine the efficacy of oral splints in reducing the intensity of pain in patients with temporomandibular joint dysfunction in both short and long-term treatment durations. Electronic databases, Cochrane Library, MEDLINE via PubMed, Web of Science, Egyptian Knowledge Bank, and EMBASE were searched for randomized controlled trials comparing different types of splints to non-occluding splints, behavioral therapy, pharmacotherapy, counseling, and no treatment. The risk of bias was assessed by using Cochrane risk of bias recommendations. Fixed and random effects were used to summarize the outcomes. The effect estimates were expressed as standardized mean differences (SMD) or risk ratios with a 95% confidence interval (CI). Subgroup analyses were carried out according to the treatment duration. Twenty-two studies met the inclusion criteria. A meta-analysis of short-term studies up to three months revealed no significant difference between the study groups. However, long-term studies exhibited a significant difference in pain reduction in favor of the control group. Total analysis revealed that the control group resulted in significant pain reduction (SMD 0.14, 95% CI 0.05-0.23, P=0.002, I2=0%). Oral splints are not effective in reducing pain intensity or improving function in patients with temporomandibular joint dysfunction.

Associations between AT-rich Interactive Domain 5B gene Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia: a Meta-analysis

  • Zeng, Hui;Wang, Xue-Bin;Cui, Ning-Hua;Nam, Seungyoon;Zeng, Tuo;Long, Xinghua
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6211-6217
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    • 2014
  • Previous genome-wide association studies (GWAS) have implicated several single nucleotide polymorphisms (SNPs) in the AT-rich interactive domain 5B (ARID5B) gene with childhood acute lymphoblastic leukemia (ALL). However, replicated studies reported some inconsistent results in different populations. Using meta-analysis, we here aimed to clarify the nature of the genetic risks contributed by the two polymorphisms (rs10994982, rs7089424) for developing childhood ALL. Through searches of PubMed, EMBASE, and manually searching relevant references, a total of 14 articles with 16 independent studies were included. Odds ratios (ORs) with 95% confidence intervals (95%CI) were calculated to assess the associations. Both SNPs rs10994982 and rs7089424 showed significant associations with childhood ALL risk in all genetic models after Bonferroni correction. Furthermore, subtype analyses of B-lineage ALL provided strong evidence that SNP rs10994982 is highly associated with the risk of developing B-hyperdiploid ALL. These results indicate that SNPs rs10994982 and rs7089424 are indeed significantly associated with increased risk of childhood ALL.

Synthesis of Primary Studies Related to Clothing Involvement by Meta-analysis (의복관여 효과에 대한 메타분석)

  • Lee, Jongnam;Yu, Haekyung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.37 no.3
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    • pp.386-398
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    • 2013
  • This study analyzes the effect of clothing involvement using meta-analysis. Metal-analysis (the analysis of analyses) is widely used in various academic areas to integrate individual empirical studies and generalize the knowledge of a specific research field. Previous studies regarding clothing involvement published since 1990 were researched from the KISS database using clothing involvement and fashion involvement as a keyword; subsequently, 127 articles were identified. Studies that had insufficient statistics or included clothing involvement as a moderating (or intervening variable) were eliminated; subsequently, 36 articles provided a total of 75 data sets that were used for the final analysis. Dependent variables were grouped into 10 categories to compare the differences between high and low involvement groups. The effect size of clothing involvement was large in non-personal information source; however, it was small in utility, brand royalty and quality. In the 7 categories of relational studies that showed homogeneity, the relation size regarding conformity was smaller than the personal information source.

Chuna Manual Therapy for Spondylolisthesis: A Systematic Review and Meta-analysis (척추전방전위증의 추나 치료에 대한 체계적 문헌 고찰 및 메타 분석)

  • Hong, Su Min;Ha, Hyun Ju;Yoon, Kwang Sik
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.4
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    • pp.65-77
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    • 2020
  • Objectives This study is aimed to evaluate the effectiveness of Chuna therapy for spondylolisthesis. Methods We searched th following 10 online databases without a language restriction (National Digital Science Library [NDSL], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS], KMBASE, MEDLINE/PubMed, Cochrane library, Ebscohost, EMBASE, Ovid, China National Knowledge Infrastru [CNKI]) to find randomized controlled trials that used Chuna therapy for spondylolisthesis. The methodological quality of each randomized controlled clinical trial was assessed using the Cochrane risk of bias tool and meta-analyses were perfomed. Results Eleven randomized controlled trials were included. Chuna therapy showed statistically significant reduction of symptoms. Meta-analysis showed positive results for Chuna therapy for spondylolisthesis in terms of therapeutic effects to traction, chinese medicine, therapeutic exercise. Conclusion In this study, we reviewed studies about Chuna therapy used for spondylolisthesis. The studies showed that Chuna therapy can significantly effective on spondylolisthesis. But according to Cochrane risk of bias evaluation method, most of the studies's risk of bias were unclear. Therefore, more high-quality studies will be needed.

Are Parent Education Programs in South Korea Really Effective? : A Meta-Analytic Study Using Journal Articles (부모교육 프로그램의 효과성 메타분석 : 국내 학술지 연구를 중심으로)

  • Lee, Jaerim;Kim, Jiae;Cha, Donghyuk;Lee, Hyanghee
    • Journal of Families and Better Life
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    • v.31 no.3
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    • pp.27-47
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    • 2013
  • The purpose of this study was to investigate whether parent education programs conducted in South Korea were effective in changing in parents' behaviors, parents' internal characteristics, and children's characteristics. We retrieved journal articles published in Korea between 2006 and 2011 using keyword searches of electronic databases. A total of 41 studies were included in our meta-analyses. The results showed that parent education programs had large positive effects on parents' behavioral changes and children's changes along with medium to large effects on parents' internal changes. The strengths of effect sizes varied depending upon program characteristics including children's age, the number of participants, participants' gender, the number of sessions, and group characteristics. This study provided powerful scientific evidence for public policies and services that aim to support and empower parents by providing parent education programs.

Analysis of trusses by total potential optimization method coupled with harmony search

  • Toklu, Yusuf Cengiz;Bekdas, Gebrail;Temur, Rasim
    • Structural Engineering and Mechanics
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    • v.45 no.2
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    • pp.183-199
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    • 2013
  • Current methods of analysis of trusses depend on matrix formulations based on equilibrium equations which are in fact derived from energy principles, and compatibility conditions. Recently it has been shown that the minimum energy principle, by itself, in its pure and unmodified form, can well be exploited to analyze structures when coupled with an optimization algorithm, specifically with a meta-heuristic algorithm. The resulting technique that can be called Total Potential Optimization using Meta-heuristic Algorithms (TPO/MA) has already been applied to analyses of linear and nonlinear plane trusses successfully as coupled with simulated annealing and local search algorithms. In this study the technique is applied to both 2-dimensional and 3-dimensional trusses emphasizing robustness, reliability and accuracy. The trials have shown that the technique is robust in two senses: all runs result in answers, and all answers are acceptable as to the reliability and accuracy within the prescribed limits. It has also been shown that Harmony Search presents itself as an appropriate algorithm for the purpose.

Effects of Simulation-Based Education for Emergency Patient Nursing Care in Korea: A MetaAnalysis (응급환자 간호를 위한 시뮬레이션 교육효과: 메타분석)

  • Hyun, Jin-Sook;Kim, Eun Ja;Han, Jung Hwa;Kim, Nahyun
    • Journal of Korean Biological Nursing Science
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    • v.21 no.1
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    • pp.1-11
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    • 2019
  • Purpose: The purpose of this review was to evaluate the effects of emergency nursing simulation program on nursing students and nurses. Methods: This systematic review was performed as per the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and using the R program meta package (version 4.9-2). RISS, KISS, and DBpia Library databases were searched for studies published between June 2000 and August 2018 using the following key words: ($Emerge^*$ OR nursing) AND ($nurs^*$ OR simulation). Selected studies were assessed for methodological quality using Risk of Bias for Non randomized Studies. Results: 7 studies were identified and all of them met the inclusion criteria. The outcome variables were significant clinical performance, self-efficacy except knowledge, and problem-solving ability. Conclusion: This review provides updated evidence of the simulation-based education program in emergency nursing. Further studies are required to increase generalizability using randomized population, research design and controlled trials with sufficient sample size. Moreover, valid measurements are needed to assess the main outcomes.

Research on the effectiveness of virtual reality technology in China's educational applications Based on 23 experimental and quasi-experimental meta-analyses (가상현실기술의 중국내 교육적 활용효과에 관한 연구 - 23개 실험과 준실험 메타분석에 기초)

  • Huang, Guan;Min, Byung-Won
    • Journal of Internet of Things and Convergence
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    • v.8 no.6
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    • pp.1-13
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    • 2022
  • The Paper Using the meta-analysis research method, first through literature retrieval to obtain 23 relevant empirical studies in China, and then using Review Manager for quantitative analysis, it is found that VR technology has a positive impact on students' overall learning effect and VR technology has a significant positive impact on all dimensions of learning effect (theoretical performance, operational performance, learning motivation, learning interest, learning attitude). There is no significant difference between the dimensions. Significant differences were found for moderating variables such as Discipline types, Teaching Length, and Teaching Method. No significant differences were found for the Academic segments and VR technology types.

The role of percutaneous neurolysis in lumbar disc herniation: systematic review and meta-analysis

  • Manchikanti, Laxmaiah;Knezevic, Emilija;Knezevic, Nebojsa Nick;Sanapati, Mahendra R.;Kaye, Alan D.;Thota, Srinivasa;Hirsch, Joshua A.
    • The Korean Journal of Pain
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    • v.34 no.3
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    • pp.346-368
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    • 2021
  • Background: Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases, percutaneous neurolysis with targeted delivery of medications is often the next step in pain management. Methods: An evidence-based system of methodologic assessment, namely, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was used. Multiple databases were searched from 1966 to January 2021. Principles of the best evidence synthesis were incorporated into qualitative evidence synthesis. The primary outcome measure was the proportion of patients with significant pain relief and functional improvement (≥ 50%). Duration of relief was categorized as short-term (< 6 months) and long-term (≥ 6 months). Results: This assessment identified one high-quality randomized controlled trial (RCT) and 5 moderate-quality non-randomized studies with an application of percutaneous neurolysis in disc herniation. Overall, the results were positive, with level II evidence. Conclusions: Based on the present systematic review, with one RCT and 5 non-randomized studies, the evidence level is II for percutaneous neurolysis in managing lumbar disc herniation.

Effect of intracanal cryotherapy on postendodontic pain: a systematic review and meta-analysis of randomized controlled trials

  • Gupta, Alpa;Aggarwal, Vivek;Gurawa, Alka;Mehta, Namrata;Abraham, Dax;Singh, Arundeep;Jala, Sucheta;Chauhan, Nishant
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.21 no.1
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    • pp.15-27
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    • 2021
  • This systematic review aimed to qualitatively and quantitatively evaluate the effectiveness of cryotherapy in the reduction of postendodontic pain. The review question was, "What will be the success rate of cryotherapy technique among human patients with postendodontic pain?". The review protocol was framed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Six studies were included in the review, and quantification of five studies was performed through a meta-analysis. In the forest plot representation of the studies comparing the control and cryotherapy groups in terms of the success rate in the management of postendodontic pain, the combined risk ratio (RR) was 0.80 (95% CI: 0.56 to 1.13) with a P value of 0.20. Based on the quantitative analysis, it can be suggested that intracanal cryotherapy does not play a significant role in reducing postendodontic pain.