• 제목/요약/키워드: Meta-Research

검색결과 1,644건 처리시간 0.034초

Comparison of porcine and human acellular dermal matrix outcomes in wound healing: a deep dive into the evidence

  • Saricilar, Erin Cihat;Huang, Sarah
    • Archives of Plastic Surgery
    • /
    • 제48권4호
    • /
    • pp.433-439
    • /
    • 2021
  • Acellular dermal matrices (ADM) are a novel graft. The goal of this systematic review is to evaluate the evidence behind differences in human and porcine ADM, irrelevant of manufacturing method, and to determine if there is enough of an evidence base to change clinical practice. An extensive literature search was performed through MEDLINE and Embase with search terms defining a population, intervention and outcome. Title and abstract exclusion were performed with other exclusion criteria. In 191 articles were found after exclusion of duplicates, with only 29 remaining following exclusions. Ten studies were found to have level I and II evidence (I=3, II=8), of which two were histopathological, one was an animal model, one was a systematic review, and six were clinical. The remaining studies were reviewed and considered for discussion, but did not hold high enough standards for medical evidence. Strong clinical evidence already exists for the use of human ADM, but questions of access, cost, and ethics require consideration of a xenograft. Histopathologically, evidence suggests minimal long-term differences between human and porcine ADM, although there is a short acute immune response with porcine ADM. Clinically, there is limited difference in outcomes, with a small range in effect of different ADM preparations. Considering the effectiveness of ADM in wound healing, more high-level research with appropriate statistical analysis to facilitate a future meta-analysis is recommended to justify a transition from human to porcine ADM.

플러그인 기법을 이용한 임베디드 시스템의 재사용 향상 기법 (A Reusability Enhancement Technique of Embedded System using Plug-In Method)

  • 김철진;이숙희;조은숙
    • 한국시뮬레이션학회논문지
    • /
    • 제18권4호
    • /
    • pp.81-94
    • /
    • 2009
  • 임베디드 시스템 개발에 있어서 재사용성이나 가변성 설계에 대한 연구가 미흡한 상태이다. 임베디드 시스템의 특성 상 새로운 디바이스를 지원할 수 있도록 설계되어야 하는데, 확장성이 고려되지 않은 임베디드 시스템의 경우 재구축해야 하는 어려움이 있다. 현재 임베디드 시스템의 개발 생산성 및 재사용성이 매우 낮으며, 이런 흐름은 소프트웨어 위기와 같이 임베디드 시스템의 유지보수 비용 증가, 개발비 증가, 시스템의 품질 저하 문제에 직면하게 될 것이다. 본 논문에서는 이와 같은 임베디드 시스템의 문제를 극복하기 위한 기반을 제공하고자 임베디드 시스템의 재사용성 프레임워크를 제시한다. 이 프레임워크를 기반으로 다양한 디바이스를 동적으로 지원할 수 있는 플러그인 기법을 제안하며, 플러그인 기법의 기반이 되는 동적 메타모델를 제시한다.

Scoping Review of Machine Learning and Deep Learning Algorithm Applications in Veterinary Clinics: Situation Analysis and Suggestions for Further Studies

  • Kyung-Duk Min
    • 한국임상수의학회지
    • /
    • 제40권4호
    • /
    • pp.243-259
    • /
    • 2023
  • Machine learning and deep learning (ML/DL) algorithms have been successfully applied in medical practice. However, their application in veterinary medicine is relatively limited, possibly due to a lack in the quantity and quality of relevant research. Because the potential demands for ML/DL applications in veterinary clinics are significant, it is important to note the current gaps in the literature and explore the possible directions for advancement in this field. Thus, a scoping review was conducted as a situation analysis. We developed a search strategy following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed and Embase databases were used in the initial search. The identified items were screened based on predefined inclusion and exclusion criteria. Information regarding model development, quality of validation, and model performance was extracted from the included studies. The current review found 55 studies that passed the criteria. In terms of target animals, the number of studies on industrial animals was similar to that on companion animals. Quantitative scarcity of prediction studies (n = 11, including duplications) was revealed in both industrial and non-industrial animal studies compared to diagnostic studies (n = 45, including duplications). Qualitative limitations were also identified, especially regarding validation methodologies. Considering these gaps in the literature, future studies examining the prediction and validation processes, which employ a prospective and multi-center approach, are highly recommended. Veterinary practitioners should acknowledge the current limitations in this field and adopt a receptive and critical attitude towards these new technologies to avoid their abuse.

The PRISMA Statement: The Characteristics of Fashion Distribution Channels in Virtual Reality

  • Jae-Min LEE
    • 유통과학연구
    • /
    • 제21권10호
    • /
    • pp.85-95
    • /
    • 2023
  • Purpose: Virtual reality's impact on fashion distribution extends beyond singular transactions, facilitating the emergence of novel collaborations. As investigating the characteristics of fashion distribution channels in virtual reality, this study explores how the fashion industry can utilize virtual reality distribution channels to their maximum capacity while minimizing potential disadvantages. Research design, data, and methodology: The approach used to gather previous studies for this study adheres to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology. This method is widely acknowledged and recommended for its systematic and transparent approach to selecting relevant literature. This kind of literature search plays a vital role in a systematic evaluation as it informs the results. Results: The finding indicates consistently a total of eight kinds of characteristics of fashion distribution channels in virtual reality. The result means that the attributes of fashion distribution channels in virtual reality are causing significant changes in the fashion industry, revolutionizing the consumer experience, and redefining the parameters of creativity and collaboration. Conclusions: In sum, the global reach and accessibility of modern technology enhance the capacity of fashion companies to expand their market presence. This facilitates their participation in intercultural interactions and allows them to serve a wide range of customers.

Design and Implementation of the Document HTML System for Preserving Content Integrity

  • Hyun Cheon Hwang;Ji Su Park;Jin Gon Shon
    • Journal of Information Processing Systems
    • /
    • 제19권3호
    • /
    • pp.334-346
    • /
    • 2023
  • An electronic document based on PDF has been widely used in customer communication between an enterprise and a customer to deliver personalized content. However, electronic documents based on PDF in the form of paper layouts are not suitable for mobile environments because of low readability and lack of interactive interaction. Even though HTML is an essential language in a mobile environment, electronic document based on PDF is still used as it has a content integrity verification feature with a digital signature. It means that a user is sacrificing user experience in a mobile environment for content integrity and using paper-layout electronic documents. In this research, we design the Document HTML specification by setting the Document HTML conformance, adding the extended meta tags, and signing the message digest with a digital signature based on public key infrastructure (PKI). Furthermore, we implemented the Document HTML system, which has REST API services to generate and verify the Document HTML, and did experimental verification of the theory. As a result, we have confirmed that the Document HTML has both content integrity and user experience on mobile. Furthermore, the Document HTML is expected to be an alternative document format to deliver personalized content from an enterprise to a customer in a mobile environment instead of the paper layout electronic document such as PDF.

Estimation of lightweight aggregate concrete characteristics using a novel stacking ensemble approach

  • Kaloop, Mosbeh R.;Bardhan, Abidhan;Hu, Jong Wan;Abd-Elrahman, Mohamed
    • Advances in nano research
    • /
    • 제13권5호
    • /
    • pp.499-512
    • /
    • 2022
  • This study investigates the efficiency of ensemble machine learning for predicting the lightweight-aggregate concrete (LWC) characteristics. A stacking ensemble (STEN) approach was proposed to estimate the dry density (DD) and 28 days compressive strength (Fc-28) of LWC using two meta-models called random forest regressor (RFR) and extra tree regressor (ETR), and two novel ensemble models called STEN-RFR and STEN-ETR, were constructed. Four standalone machine learning models including artificial neural network, gradient boosting regression, K neighbor regression, and support vector regression were used to compare the performance of the proposed models. For this purpose, a sum of 140 LWC mixtures with 21 influencing parameters for producing LWC with a density less than 1000 kg/m3, were used. Based on the experimental results with multiple performance criteria, it can be concluded that the proposed STEN-ETR model can be used to estimate the DD and Fc-28 of LWC. Moreover, the STEN-ETR approach was found to be a significant technique in prediction DD and Fc-28 of LWC with minimal prediction error. In the validation phase, the accuracy of the proposed STEN-ETR model in predicting DD and Fc-28 was found to be 96.79% and 81.50%, respectively. In addition, the significance of cement, water-cement ratio, silica fume, and aggregate with expanded glass variables is efficient in modeling DD and Fc-28 of LWC.

A Methodology of Optimal Design for Solar Heating and Cooling System Using Simulation Tool

  • Lee, Dongkyu;Nam, Hyunmin;Lee, Byoungdoo
    • 국제학술발표논문집
    • /
    • The 6th International Conference on Construction Engineering and Project Management
    • /
    • pp.540-543
    • /
    • 2015
  • Solar energy is one of the most important alternative energy sources which have been shown to meet high levels of heating and cooling demands in buildings. However, the efficiencies to satisfy these demands using solar energy significantly vary based on the characteristics of individual building. Therefore, this paper is focused on developing the methodology which can help to design optimal solar system for heating and cooling to be in cooperated within the existing buildings according to their load profiles. This research has established the Solar Heating and Cooling (SHC) system which is composed of collectors, absorption chiller, boiler and heat storage tank. Each component of SHC system is analyzed and made by means of Modelica Language and Pistache tool is verified the results. Sequential approximate optimization (SAO) and meta-models determined to 15 design parameters to optimize SHC system. Finally, total coefficient of performance (COP) of the entire SHC system is improved approximately 7.3% points compared to total COP of the base model of the SHC system.

  • PDF

A Quest of Design Principles of Cognitive Artifacts through Case Analysis in e-Learning: A Learner-Centered Perspective

  • PARK, Seong Ik;LIM, Wan Chul
    • Educational Technology International
    • /
    • 제10권1호
    • /
    • pp.1-23
    • /
    • 2009
  • Learners are often posited in a paradoxical situation where they are not fully involved in decision making processes on how to learn, in designing their tools. Cognitive artifacts in e-learning are supposed to effectively support learner-centered e-learning. The purpose of the study is to analyze cases of cognitive artifacts and to inquire those design principles for facilitating the learner-centered e-learning. Four research questions are suggested: First, it will be analyzed the characteristics of learners with respect to design of cognitive artifacts for supporting the learner-centered e-learning. Second, characteristics of four cases to design cognitive artifacts in learner-centered e-learning environment are analyzed. Third, it will be suggested the appropriate design principles of cognitive artifacts to facilitating learner-centered learning in e-learning environment. Four cases of cognitive artifacts design in learner-centered e-learning was identified as follows: Wiki software as cognitive artifacts in computer-supported collaborative learning; 'Play Around Network (PAN)' as cognitive artifact to monitor learning activities in knowledge community; Knowledge Forum System (KFS) as a cognitive artifact in knowledge building; cognitive artifacts in Courses-as-seeds applied meta-design. Five design principles are concluded as follows: Promoting externalization of cognitive artifacts to private media; Helping learners to initiate their learning processes; Encouraging learners to make connections with other learners' knowledge building and their cognitive artifacts; Promoting monitoring of participants' contributions in collaborative knowledge building; Supporting learners to design their cognitive artifacts.

산후 오로부절 및 자궁 복구 불완전에 대한 생화탕(生化湯) 치료의 효과 : 체계적 문헌고찰과 메타분석 (Saenghwa-tang Treatment on Postpartum Prolonged Lochia and Uterine Subinvolution: a Systematic Review and Meta-Analysis)

  • 송지윤;김동철
    • 대한한방부인과학회지
    • /
    • 제36권4호
    • /
    • pp.121-139
    • /
    • 2023
  • Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of Saenghwa-tang treatment on postpartum prolonged lochia and uterine subinvolution. Methods: Researchers searched for randomized controlled trial of based on postpartum prolonged lochia, uterine subinvolution and Saenghwa-tang. The paper search was conducted through 6 online databases on August 10, 2023. Results: 8 studies were included after selection and exclusion criteria. 5 studies compared Saenghwa-tang alone with western medicine. 3 studies compared combined treatment of Saenghwa-tang and western medicine, with western medicine alone. Comparing with control group, the treatment group showed statistically significant improvement on total effective rate, uterine involution, serum fibrinogen, D-dimer, viscosity of blood and plasma, Erythrocyte aggregation, and various symptoms. Conclusions: This study suggests that Saenghwa-tang has benefit for treating prolonged lochia and uterine subinvolution. For reliable evidence, further research is needed to establish safety of Saenghwa-tang, standardize diagnosis criteria and specify the treatment course.

A three-dimensional two-hemisphere model for unmanned aerial vehicle multiple-input multiple-output channels

  • Zixu Su;Wei Chen;Changzhen Li;Junyi Yu;Guojiao Gong;Zixin Wang
    • ETRI Journal
    • /
    • 제45권5호
    • /
    • pp.768-780
    • /
    • 2023
  • The application of unmanned aerial vehicles (UAVs) has recently attracted considerable interest in various areas. A three-dimensional multiple-input multiple-output concentric two-hemisphere model is proposed to characterize the scattering environment around a vehicle in an urban UAV-to-vehicle communication scenario. Multipath components of the model consisted of lineof-sight and single-bounced components. This study focused on the key parameters that determine the scatterer distribution. A time-variant process was used to analyze the nonstationarity of the proposed model. Vital statistical properties, such as the space-time-frequency correlation function, Doppler power spectral density, level-crossing rate, average fade duration, and channel capacity, were derived and analyzed. The results indicated that with an increase in the maximum scatter radius, the time correlation and level-crossing rate decreased, the frequency correlation function had a faster downward trend, and average fade duration increased. In addition, with the increase of concentration parameter, the time correlation, space correlation, and level-crossing rate increased, average fade duration decreased, and Doppler power spectral density became flatter. The proposed model was compared with current geometry-based stochastic models (GBSMs) and showed good consistency. In addition, we verified the nonstationarity in the temporal and spatial domains of the proposed model. These conclusions can be used as references in the design of more reasonable communication systems.