• Journal of the Korean Geotechnical Society
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• v.40 no.4
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• pp.169-178
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• 2024

While stable mid- to large-scale underground hydrogen storage infrastructures are needed to meet the rapidly increasing demand for hydrogen energy, evaluating the safety of explosion vibrations in adjacent buildings is becoming important because of gas explosions in underground hydrogen storage facilities. In this study, a numerical analysis of vibration safety effects on nearby building structures was performed assuming a hydrogen gas explosion disaster scenario in a low-depth underground hydrogen storage facility. A parametric study using a meta-model was conducted to predict changes in ground dynamic behavior for each combination of ground properties and to analyze sensitivity to geotechnical influencing factors. Directly above the hydrogen storage facility, the unit weight of the ground had the greatest influence on the change in ground vibration due to the explosion, whereas, farther away from the facility, the sensitivity of dynamic properties was found to be high. In addition, in evaluating the vibration stability of ground building structures based on the predicted ground vibration data and blasting vibration tolerance criteria, in the case of large reinforced concrete building structures, the ground vibration safety was guaranteed with a separation distance of about 10-30 m.

• Korean Journal of Oriental Medicine
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• v.13 no.2 s.20
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• pp.101-112
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• 2007

Objective : This study was aimed to review the trend of clinical research articles of acupuncture and moxibustion from the year of 1995 to 2006. Methods : The retrieving and analyzing period were from January 1995 to July 2006. Articles were collected by retrieving Pubmed database. Search terms were as follows; 'Acupuncture', 'Acupuncture & Meridian', 'Moxibustion'. After reviewing articles by our pre-defined criteria, Correlation was assessed qualitatively between contents of the final selected articles and those of Korea Institute of Oriental Medicine. Results : The number of acupuncture research articles have increased with higher rate since the year of 2000. In the field of medical devices, the articles were sparsely existed. The percentage of clinical acupuncture research articles was 75%. However, in the category of Korean investigators' researches, it was 46%. Publications by Korean investigators were concentrated to several specific journals of which their impact factor were below 1 point. Conclusion : There needs more qualifying studies in acupuncture studies which are represented by impact factor in Journal Citation Reports. It is necessary to research and develop the medical devices quantatively rating the outcome of acupuncture trials. The secondary research, such as, systematic reviews, meta-analysis, would be a key approach to evaluate the effectiveness and safety of acupuncture treatments. Moxibustion research would be noticeable in regard to its historical effectiveness and its variable indications.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6905-6910
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• 2014

Background: The relation ofsurvivin gene expression to survival and surgical prognostic factors in the patients with endometrial carcinoma is unclear. Materials and Methods: In this study, 62 cases who were operated due to endometrial carcinoma were investigated between 2003 and 2011 in the the gynecological oncology clinic of Female Disease Training and Investigation Hospital of Etlik Zubeyde, Hanim, Turkey. Clinical and surgical prognostic factors were investigated by screening the records of these cases. With the standard streptavidin-biotin immune peroxidase method, cytoplasmic and nuclear expression of survivin was investigated in sections with specific antibodies (1:100, diagnostic Bio Systems, USA) primer. The aim was to elucidate any relation between survivin expression and defined prognostic factors and survival. Results: There was no statistically significant relationship between cytoplasmic and nuclear indexes identified for survivin and age, body mass index, the levels of preoperative hemoglobin, platelet and Ca 125, stage, grade, lymph node meastasis, the number of meta statical lymph nodes (total, paraaortic and pelvic), myometrial invasion, serosal invasion, adnexal involvement, the presence of acid in the first diagnosis, the involvement of omentum, the adjuvant treatment application of the cases, the presence of recurrence and rate of mortality (p>0.05). Statistical significance was noted for the presence of advanced stage lymph node metastasis (pelvic, paraaortic, pelvic and paraaortic), serosal involvement, positive cytology, lymph vascular space invasion, intra abdominal metastasis, and omentum involvement. When investigated the relation between cytoplasmic and nuclear survivin indexes and total survival, the result was not statistically significant (p>0.05). Conclusions: In our study, there was no statistically significant relationship between the rates of cytoplasmic and nuclear survivin expression with identified prognostic factors and total or non-disease survival.

• Journal of the Ergonomics Society of Korea
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• v.34 no.5
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• pp.377-399
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• 2015

Objective: The aim of this study is to understand and identify the critical issues in vision research area using content analysis and network analysis. Background: Vision, the most influential factor in information processing, has been studied in a wide range of area. As studies on vision are dispersed across a broad area of research and the number of published researches is ever increasing, a bibliometric analysis towards literature would assist researchers in understanding and identifying critical issues in their research. Method: In this study, content and network analysis were applied on the meta-data of literatures collected using three search keywords: 'visual search', 'eye movement', and 'eye tracking'. Results: Content analysis focuses on extracting meaningful information from the text, deducting seven categories of research area; 'stimuli and task', 'condition', 'measures', 'participants', 'eye movement behavior', 'biological system', and 'cognitive process'. Network analysis extracts relational aspect of research areas, presenting characteristics of sub-groups identified by community detection algorithm. Conclusion: Using these methods, studies on vision were quantitatively analyzed and the results helped understand the overall relation between concepts and keywords. Application: The results of this study suggests that the use of content and network analysis helps identifying not only trends of specific research areas but also the relational aspects of each research issue while minimizing researchers' bias. Moreover, the investigated structural relationship would help identify the interrelated subjects from a macroscopic view.

• Korean Journal of Adult Nursing
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• v.27 no.5
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• pp.527-536
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• 2015

Purpose: The purpose of this study was to analyze the trend of nursing theories by Korean Journal of Adult Nursing (KJAN) for the last five years and to provide future directions for improvement. Methods: The study analyzed data collected from 323 research papers published in KJAN between 2010~2014. Descriptive analysis was conducted with a focus on frequency and percentage for the quantitative analysis. Qualitative analysis was performed for the analysis of nursing theories. Results: As for research topics, the analysis results based on the meta-paradigm of nursing show that the most frequent factors of analysis were adult patients in the area of human beings, hospitals in the area of environment, depression, anxiety, and suicide in the area of health, and all the influential factors in the area of nursing. The analysis results of uses of nursing theories in the papers reveal that only 4(1.2%) out of total 323 papers used the nursing theories, which indicates that the linkage and utilization of nursing theories in the published papers for the last five years were poor. Conclusion: We needs to make efforts at the society level to activate nursing theory utilization in research which is beloved to connect nursing practice, education, and research.

• Journal of Korean Medical classics
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• v.23 no.2
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• pp.89-105
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• 2010

Research methodology on Traditional Medicine in East Asia refers to logical thinking system, empirical positivism system and methodology of developing these knowledge systems. Logical thinking system of abstract concepts such as analogy or abduction and positivism system of reasonable explanation such as the five elements and their characteristic theory have been used in various ways empirically or in the form of humanities and knowledge system was developed through parallel structure of empirical positivism and exegetical studies. After the 16th century, evidence was required along with the tradition of putting emphasis on rationality, logicality and empirical positivism and characteristics of medical humanities can be found in emphasizing on medical ethics. Data that can be considered as structural review paper or meta analysis from original data of research on Traditional East Asian Medicine should be evaluated as historical evidence which is equivalent to specialist opinion, descriptive disease research, single case report or case series. Historical evidence based medicine is a research method using Historical evidence to selectively support data that are faithful to traditional theory with higher possibility to be used in future traditional east Asian medicine that links between traditional knowledge and scientific research methodology. Moreover, historical evidence based medicine tries to re-evaluate the value of traditional knowledge and ultimately, guides the direction of development of traditional medicine through scientific rationality based on history and culture.

• Journal of East-West Nursing Research
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• v.26 no.2
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• pp.118-129
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• 2020

Purpose: The purpose of this study was to analyze the topic trend of domestic simulation nursing education research using text network analysis(TNA). Methods: This study was conducted in four steps. TNA was performed using the NetMiner (version 4.4.1) program. Firstly, 245 articles from 4 databases (RISS, KCI, KISS, DBpia) published from 2008 to 2018, were collected. Secondly, keyword-forms were unified and representative words were selected. Thirdly, co-occurrence matrices of keywords with a frequency of 2 or higher were generated. Finally, social network-related measures-indices of degree centrality and betweenness centrality-were obtained. The topic trend over time was visualized as a sociogram and presented. Results: 178 author keywords were extracted. Keywords with high degree centrality were "Nursing student", "Clinical competency", "Knowledge", "Critical thinking", "Communication", and "Problem-solving ability." Keywords with high betweenness centrality were "CPR", "Knowledge", "Attitude", "Self-efficacy", "Performance ability", and "Nurse." Over time, the topic trends on simulation nursing education have diversified. For example, topics such as "Neonatal nursing", "Obstetric nursing", "Pediatric nursing", "Blood transfusion", "Community visit nursing", and "Core basic nursing skill" appeared. The core-topics that emerged only recently (2017-2018) were "High-fidelity", "Heart arrest", "Clinical judgment", "Reflection", "Core basic nursing skill." Conclusion: Although simulation nursing education research has been increasing, it is necessary to continue studies on integrated simulation learning designs based on various nursing settings. Additionally, in simulation nursing education, research is required not only on learner-centered educational outcomes, but also factors that influence educational outcomes from the perspective of the instructors.

• Informatization Policy
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• v.22 no.3
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• pp.3-15
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• 2015

This study aims to examine the recent trend of domestic researches on the Internet of Things(IoT) which has drawn a lot of attention in the field of ICT. This meta-analysis analyzes 101 studies published in academic journals from 2010, focusing on research topics, methods and the fields of study. The results show that the research topics of most used studies were related to the technological and industrial issues, and especially in the technical field, the major topic was suggesting new IoT technology. The most research method was testing research followed by the literature review. Even though engineers are holding the mainstream of the IoT technology, some experts in the field of social science release their articles nowadays. These results indicate that the IoT has a great ripple effect both technologically and socioculturally, and researches need to be vitalized in the fields of industry, service, policy and institution as well as technological fields. In addition, the research for the future should extend methodological diversity and take more convergence approaches in a variety of fields.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6407-6412
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• 2015

Purpose: To predict prostatic carcinoma using a logistic regression model on prebiopsy peripheral blood samples. Materials and Methods: Data of a total of 873 patients who consulted Urology Outpatient Clinics of Fatih Sultan Mehmet Training and Research Hospital between February 2008 and April 2014 scheduled for prostate biopsy were screened retrospectively. PSA levels, prostate volumes, prebiopsy whole blood cell counts, neutrophil and platelet counts, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), biopsy results and Gleason scores in patients who had established diagnosis of prostate cancer (PCa) were evaluated. Results: This study was performed on a total of 873 cases, with an age range 48-76 years, divided into three groups as for biopsy results. with diagnoses of benign prostatic hyperplasia (BPH) (n=304, 34.8 %), PCa (n=265, 30.4 %) and histological prostatitis (n=304; 34.8 %). Intra- and intergroup comparative evaluations were performed. White blood cell and neutrophil counts in the histological prostatitis group were significantly higher than those of the BPH and PCa groups (p=0.001; p=0.004; p<0.01). A statistically significant intergroup difference was found for PLR (p=0.041; p<0.05) but not lymphocyte count (p>0.05). According to pairwise comparisons, PLR were significantly higher in the PCa group relative to BPH group (p=0.018, p<0.05, respectively). Though not statistically significant, higher PLR in cases with PCa in comparison with the prostatitis group was remarkable (p=0.067, and p>0.05, respectively). Conclusions: Meta-analyses showed that in patients with PSA levels over 4 ng/ml, positive predictive value of PSA is only 25 percent. Therefore, novel markers which can both detect clinically significant prostate cancer, and also prevent unnecessary biopsies are needed. Relevant to this issue in addition to PSA density, velocity, and PCA3, various markers have been analyzed. In the present study, PLR were found to be the additional predictor of prostatic carcinoma.

• Korean Journal of Veterinary Research
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• v.35 no.3
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• pp.471-480
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• 1995

The purpose of this experiment was to develop a simple and reliable HPLC method for the detection of ciprofloxacin in chicken serum and to provide a basic data on pharmacokinetic parameters after oral and intramuscular administration. The results obtained were as follows: 1. 0.2% meta-phosphoric acid: acetonitrile(7:3, v/v) solution had a high and regular recovery rates and was selected as an extraction solution. 2. The recovery rates of ciprofloxacin were 83-97% with the selected solution in chicken serum and the detection limit was 50ng/ml in serum. 3. Ka(abosorption rate constant) were 3.652 1/h in fasted group and 0.880 1/h in non-fasted group, and Ke (elimination rate constant) were 0.061 1/h and 0.133 1/h, respectively. 4. The highest concentration in serum after intramuscular injection was 840ng/ml within 15-30min and 160-324ng/ml in 1.1-3.2 hours after oral administration. 5. The time course of blood concentration fits well into a 2 compartment model. 6. On oral administration of ciprofloxacin with feed, ciprofloxacin was absorbed more slowly and the amount of absorbed was smaller than that of in fasted chickens. 7. Blood concentration of ciprofloxacin increased in a dose-dependent manner after intramusclular and oral administraiton.