• Title/Summary/Keyword: Meta study

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Dental age estimation using cone-beam computed tomography: A systematic review and meta-analysis

  • Faezeh Yousefi;Younes Mohammadi;Mehrnaz Ahmadvand;Parnian Razaghi
    • Imaging Science in Dentistry
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    • v.53 no.2
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    • pp.91-99
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    • 2023
  • Purpose: This systematic review aimed to investigate the correlation between chronological age and dental pulp volume in cone-beam computed tomography (CBCT). Materials and Methods: The literature was searched in 4 databases(PubMed, Scopus, Web of Science, and Google Scholar). Within each study, the outcome of interest was the correlation (r) between chronological age and pulp volume. A random-effect meta-analysis was conducted. Subgroup analysis was carried out according to sex and tooth type. Results: Of 5,693 identified studies, 27 fulfilled the inclusion criteria and were selected for meta-analysis. These articles focused on single-rooted teeth (n=21), multi-rooted teeth (n=6), maxillary teeth (n=14), mandibular teeth (n=6), and maxillary and mandibular teeth (n=12). The relationship between chronological age and dental pulp volume was examined in the entire population (r= -0.67), men (r= -0.75), and women (r= -0.77) in single- and multi-rooted teeth. The results of the total population analysis showed a relatively strong negative relationship between age and pulp volume. Conclusion: This study suggested that CBCT is a reliable and repeatable tool for dental age estimation. A strong inverse relationship was observed between pulp chamber volume and age. Further studies on the correlation between chronological age and pulp volume of multi-rooted teeth may be beneficial.

Implement of Contents information quality using u-smart tourist information (u-스마트 관광정보를 이용한 콘텐츠정보품질 구현)

  • Sun, Su-Kyun
    • Journal of Digital Convergence
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    • v.11 no.5
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    • pp.437-442
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    • 2013
  • To IT convergence study tourism the convergence of IT and tourism in recent years has emerged as a discipline in the future. The purpose of this study, quality of tourism information systems using u-smart content information about design and implementation. This create the basic processes and data that you can analyze the average propensity of tourism and tourism tourists tourist information quality by implementing patterns of information in the template library content can be. Tourist information and tourist's propensity to take advantage of smart apps and XMI created and implemented by the appropriate content information on the quality of the tourism information content can be seen in real-time, this paper have the advantage of being Connection relationship meta-model through the inter-related processes, as well as Smart App can be meta-modeled. Quality by implementing the content of the information tourism information and helps in the development of the future tourism policy, in which you can design a digital model to determine the propensity of tourists.

Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Prostate Cancer: a Systematic Review with Meta-analysis

  • Wang, Kai;Peng, Hong-Ling;Li, Long-Kun
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5665-5669
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    • 2012
  • Background: The vascular endothelial growth factor (VEGF) mediates vasculogenesis and angiogenesis through promoting endothelial cell growth, migration and mitosis, and has involvement in cancer pathogenesis, progression and metastasis. However, the prognostic value of VEGF in patients with prostate cancer remains controversial. Objectives: The aim of our study was to evaluate the prognostic value of VEGF in prostate cancer, and summarise the results of related research on VEGF. Methods: In accordance with an established search strategy, 11 studies with 1,529 patients were included in our meta-analysis. The correlation of VEGF-expression with overall survival and progression-free survival was evaluated by hazard ratio, either given or calculated. Results: The studies were categorized by introduction of the author, demographic data in each study, prostate cancer-relatived information, VEGF cut-off value, VEGF subtype, methods of hazard ratio (HR) estimation and its 95% confidence interval (CI). High VEGF-expression in prostate cancer is a poor prognostic factor with statistical significance for OS (HR=2.32, 95%CI: 1.40-3.24). However, high VEGF-expression showed no effect on poor PFS (HR=1.30, 95%CI: 0.88-1.72). Using Begg's, Egger's test and funnel plots, we confirmed lack of publication bias in our analysis. Conclusion: VEGF might be regarded as a prognostic maker for prostate cancer, as supported by our meta-analysis. To achieve a more definitive conclusion enabling the clinical use of VEGF in prostate cancer, we need more high-quality interventional original studies following agreed research approaches or standards.

Effects of Nursing Interventions for Fall Prevention in Hospitalized Patients: A Meta-analysis (입원 환자 낙상예방 간호중재 효과에 대한 메타분석)

  • Kim, Yoon Lee;Jeong, Seok Hee
    • Journal of Korean Academy of Nursing
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    • v.45 no.4
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    • pp.469-482
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    • 2015
  • Purpose: The purpose of this study was to identify which nursing interventions are the most effective in fall prevention for hospitalized patients. Methods: From 3,675 papers searched, 34 were selected for inclusion in the meta-analysis. Number of fallers, falls, falls per 1,000 hospital-days, and injurious falls, fall protection activity, knowledge related to falls, and self-efficacy about falls were evaluated as outcome variables. Data were analyzed using the Comprehensive Meta Analysis (CMA) 2.2 Version program and the effect sizes were shown as the Odd Ratio (OR) and Hedges's g. Results: Overall effect size of nursing interventions for fall prevention was OR=0.64 (95% CI: 0.57~0.73, p <.05) and Hedges's g= - 0.24. The effect sizes (OR) of each intervention ranged from 0.34 to 0.93, and the most effective nursing intervention was the education & environment intervention (OR=0.34, 95% CI: 0.28~0.42, p<.001), followed by education intervention (OR=0.57, 95% CI: 0.50~0.67, p=.001). Subgroup analyses showed that multifaceted interventions (OR=0.76, 95% CI: 0.73~0.79, p<.001) were more effective than unifactorial interventions, and that activities for prevention of falls (OR=0.08, 95% CI: 0.05~0.15, p<.001) showed the largest effect size among outcome variables. Conclusion: Falls in hospitalized patients can be effectively prevented using the nursing interventions identified in this study. These findings provide scientific evidence for developing and using effective nursing interventions to improve the safety of hospitalized patients.

The Effectiveness of Moxibustion Treatment for Primary Dysmenorrhea: A Systematic Review and Meta-Analysis (원발성 월경곤란증의 뜸 치료에 대한 체계적 문헌고찰 및 메타분석)

  • Lee, Hye-In;Baek, Seon-Eun;Lee, Ho-Jung;Park, Kyoung-Sun;Lee, Jin-Moo;Yoo, Jeong-Eun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.30 no.2
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    • pp.107-119
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    • 2017
  • Objectives: The purpose of this study is to investigate the effectiveness of moxibustion for primary dysmenorrhea (PD). Methods: We searched 10 electronic databases (CNKI, WANFANG, VIP, AMED, CiNii, Embase, PubMed, Cochrane, OASIS, Korea Traditional Knowledge Portal) to identify eligible studies published before November 2016. We included randomized controlled clinical trials (RCTs) using moxibustion for primary dysmenorrhea. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results: Ten RCT studies were eligible in our review. The overall risk of bias was evaluated as unclear. The meta-analysis of 4 trials indicated that favorable results for the use of moxibustion. Conclusions: This systematic review and meta-analysis of clinical trials suggests that moxibustion can achieve good efficacy for PD patients. However, because of studies included analysis was biased due to unclear risk of bias and unreliable study design, future high-quality RCT studies are needed to determine the association moxibustion with PD.

Survival Rate of Breast Cancer in Iran: A Meta-Analysis

  • Abedi, Ghasem;Janbabai, Ghasem;Moosazadeh, Mahmood;Farshidi, Fereshte;Amiri, Mohammad;Khosravi, Ahmad
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4615-4621
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    • 2016
  • Background: There has not been a general estimation about survival rates of breast cancer cases in Iran. Therefore, the present study aimed to assess survival using a meta-analysis. Materials and Methods: International credible databases such as Scopus, Web of Science, PubMed, Science direct and Google Scholar and Iranian databases such as Magiran, Irandoc and SID, from 1997 to 2015 were searched. All articles covering survival rate of breast cancer were entered into the study without any limits. Quality assessment of the articles and data extraction were performed by two researchers using the modified STROBE checklist, which includes 12 questions. Articles with scores greater than 8 were included in the analysis. A limitation of this meta-analysis was different methods for presenting of results in the papers surveyed. Results: A total of 21 articles with a sample of 12,195 people were analyzed. The one-year, three-year, five-year and ten-year survival rates of breast cancer in Iran were estimated to be 95.8% (94.6-97.0), 82.4% (79.0-85.8), 69.5% (64.5-74.5), 58.1% (39.6-76.6), respectively. The most important factors affecting survival of breast cancer were age, number of lymph nodes involved, size of the tumor and the stage of the disease. Conclusion: The five- and ten- year survival rates in Iran are lower than in developed countries. Conducting breast cancer screening plan support (including regular clinical examination, mammography), public training and raising awareness should be helpful in facilitating early diagnosis and increasing survival rates for Iranian women.

A Study on the Fundamental Mechanical Properties of Hydrophobic Cementeous Mortar using Silane Admixtures (실란계 혼화제를 활용한 소수성 시멘트 모르타르의 기초물성 연구)

  • Oh, Hongseob
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.6 no.2
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    • pp.79-86
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    • 2018
  • In this study, emulsion type hydrophobic admixture was prepared by mixing polyvinyl alcohol surfactant, polymethyl hydro-siloxane and meta kaolin, and the compressive strength and mechanical properties such as permeability and contact angle test of the mortar were evaluated. The developed hydrophobic admixture showed no decrease in strength and the mortar specimen with magnesium oxide developed the early strength. In the case of permeability, total seepage was significantly decreased when the hydrophobic admixture was directly mixed with the mortar, but the effect of meta kaolin contained in hydrophobic admixture was not significant. The surface of specimens coated with hydrophobic admixture shows that the contact angle on the surface was highly increased compared with reference mortar specimen. Further researches to obtain the optimum mix proportion of the PVA fiber, nano-silica and meta kaolin for producing the super-hydrophobic surface are required.

The Effect of Laser and Joint Mobilization Techniques on Tennis Elbow: A Meta-Analysis (테니스 주(tennis elbow)에 대한 레이저치료와 관절가동화기법의 효과: 메타분석)

  • Moon, Mee-Hyang;Nam, Chung-Mo;Chung, Yi-Jung
    • Physical Therapy Korea
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    • v.10 no.3
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    • pp.91-107
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    • 2003
  • We processed meta-analysis to test if the effects of laser therapy and mobilization techniques are evidence-based practice for treating tennis elbow. By researching and collecting the results of previous studies on tennis elbow, we inquired into the difference in the effects of each treatment methods on pain, grip strength, and ROM. A total of 10 international and domestic articles on the treatments of tennis elbow were selected for this study, including 7 articles on the effect of laser therapy and 3 on mobilization techniques. According to the qualitative meta-analysis, all 7 of the articles on laser therapy and 1 of the mobilization technique were double-blinded and randomized the subjects, and all of the 10 studies were designed in a high quality research, using statistics. The results of the studies on laser therapy showed in terms of statistical significance: 4 out of 7 did not decrease pain after therapy, and 3 out of 5 did not increase grip strength after therapy. In the studies on the effects of mobilization technique, both the 2 studies significantly increased grip strength after therapy. For other studies which measured ROM and tension, the mobilization therapy increased ROM significantly, and decreased tension significantly. The results of our study are shown in a diverse form in terms of the effects of different therapy techniques. This is related to the accuracy of the measurement tools for assessments and diagnoses. Further qualitative studies on the evidence-based practice and researches on tennis elbow are needed.

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Effect of Community-based Rehabilitation on Patients with Brain Injury: Meta-analysis Based on the ICF Model (뇌손상 환자의 지역사회재활(CBR) 프로그램의 효과: ICF 모델에 근거한 메타분석)

  • Cha, Yu-Jin;Kim, Se-Yun
    • The Journal of the Korea Contents Association
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    • v.14 no.3
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    • pp.203-214
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    • 2014
  • In this study, a meta-analysis was conducted to investigate the effect of community-based rehabilitation on patients with brain injury by ICF factor in previous studies and examine the application of recent community-based rehabilitation program. Total 15 articles that satisfied the selection criteria were divided by ICF factors to obtain the effect size. Homogeneity and publication bias were tested for those selected papers. As a result, the overall effect size of community-based rehabilitation was 0.22; the effect size by physical function and structure among the ICF factors came to be 0.21; and the effect size of activity and participation was 0.20, indicating a small effect size. The studies involved in a meta-analysis were considered as the absence of heterogeneity and publication bias, which indicates that the results of this study are subjectively reliable. These results well explained the level of change on ICF factors, especially physical function and structure, activity and participation, in other words, the intervention effect of community-based rehabilitation on patients with brain injury.

Lack of Association of the Cyclooxygenase-2 Gene 8473T>C Polymorphism with Breast Cancer Risk: a Meta-analysis

  • Yang, Xi;Zhao, Fen;Li, Yue-Hua;Huang, Min;Huang, Ying;Yi, Cheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9693-9698
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    • 2014
  • Background: Associations between the 8473T>C polymorphism (rs5275) in the cyclooxygenase-2 (COX-2) gene and breast cancer (BC) risk are still inconclusive and ambiguous. The aim of this meta-analysis was to comprehensively estimate the genetic risk of 8473T>C polymorphism in the COX-2 gene for BC. Materials and Methods: We searched PubMed, Web of Science, Medline, Chinese biomedical (CBM), Weipu, China national knowledge infrastructure (CNKI), and Wanfang databases, covering all publications (last search was updated on Aug 17, 2014). Statistical analyses were performed using Revman 5.3 and STATA 10.0 software. Results: A total of 6,720 cases and 9,794 controls in 12 studies were included in this study. The results indicated no significant associations between the 8473T>C polymorphism of the COX-2 gene and BC risk for the CC+TC vs TT model (pooled odds ratio (OR)=0.97, 95% confidence interval (CI)=0.90-1.03, and p=0.29). On subgroup analysis, we also found that subdivision on ethnicity among Caucasians, Asians and others also revealed no relationship with BC susceptibility. With the study design (CC+TC vs TT), no significant associations were found in either population-based case-control studies (PCC), or hospital-based case-control studies (HCC). Conclusions: This present meta-analysis suggests that the 8473T>C polymorphism in the COX-2 gene is not a conspicuous low-penetrant risk factor for developing BC.