• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5411-5416
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• 2014

Background: A number of studies have reported relationships of CYP2E1 RsaI/PstI polymorphisms with susceptibility to lung cancer in Chinese population. However, the epidemiologic results have been conflictive rather than conclusive. The purpose of this study was to address the associations of CYP2E1 RsaI/PstI polymorphisms with lung cancer risk in Chinese population comprehensively. Materials and Methods: Systematic searches were conducted in the PubMed, Science Direct, Elsevier, CNKI and Chinese Biomedical Literature Databases. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to estimate the strength of association. Results: Overall, we observed a decreased lung cancer risk among subjects carrying CYP2E1 RsaI/PstI c1/c2 and c1/c2+c2/c2 genotypes (OR=0.76, 95%CI: 0.64-0.90 and OR=0.78, 95%CI: 0.66-0.93, respectively), as compared with subjects carrying the c1/c1 genotype. In subgroup analysis, we observed a decreased lung cancer risk among c1/c2 carriers in hospital-based studies (OR=0.81, 95%CI: 0.68-0.98) and among carriers with c1/c2 and c1/c2+c2/c2 genotypes in population-based studies(OR=0.57, 95%CI: 0.42-0.79 and OR=0.58, 95%CI: 0.43-0.79, respectively), as compared with subjects carrying the c1/c1 genotype. Limiting the analysis to studies with controls in Hardy-Weinberg equilibrium (HWE), we similarly observed a decreased lung cancer risk among c1/c2 and c1/c2+c2/c2 carriers (OR=0.73, 95%CI: 0.60-0.88 and OR=0.73, 95%CI: 0.60-0.88, respectively), as compared with c1/c1. Conclusions: Our results suggested that CYP2E1 RsaI/PstI c1/c2 and c1/c2+c2/c2 variants might be a protective factor for developing lung cancer in Chinese population. Further well-designed studies with larger sample size are required to verify our findings.

• Journal of KIISE:Software and Applications
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• v.37 no.12
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• pp.892-908
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• 2010

Services in SOA are typically perceived as black-box to service consumers, and can be dynamically evolved at runtime, and run on a number of unknown and heterogeneous environments. Because of these characteristics of the services, effective and efficient monitoring of various aspects on services is an essential functionality for autonomous management of service. But the problem with or limitation in conventional or existing approaches is, that they focus on services themselves, ignoring the effects by business processes. Consequently, there is a room for service monitoring which provides more useful information of business level by acquisition of only external monitoring data that depend on specific BPEL engine and middleware. Moreover, there is a strong demand to present effective methods to reduce monitoring overhead which can degrade quality of services. EDA can cope with such limitations in SOA by collecting and analyzing events efficiently. In this paper, we first describe EDA benefits in service monitoring, and classify monitorring target, and present an appropriate monitoring method for each monitoring target. Also to provide the applicability of our approach, an event meta-model is defined, and event processing model and architecture based on the meta-model are proposed. And, with the proposed architecture and method, we implement a prototype of an event-driven dynamic monitoring framework which can collect and process internal and external data at runtime. Finally, we present the result of a case study to demonstrate the effectiveness and applicability of the proposed approach.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.3
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• pp.207-221
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• 2020

This study conducted a meta-analysis on the effects of innovation, risk-taking, and enterprising on entrepreneurship. From 2013 to 2020, 392 papers, which were judged as quantitative research from doctoral and master thesis, and academic journals published in Korea were selected as research subjects. 28 duplicates of thesis and thesis are excluded. A total of 52 papers were finally selected, excluding 312 papers that were insufficient to be used as research data because there were no statistical values such as correlation coefficients. For the 52 selected papers, the homogeneity of the variables was first verified. As a result of the homogeneity test, the innovativeness, risk-taking, initiative, and entrepreneurship education all showed great effects on heterogeneity, and the average effect size was analyzed by random effect model. The average effect size analyzed was 0.38 ~ 0.49, and all four variables showed moderate average effect size. As a result of analyzing the average effect size by forest plot, all showed proper results. From the results of funnel plot analysis of entrepreneurship education, published errors were confirmed asymmetric. Research data on entrepreneurship education shows that it cannot represent the whole. It is a structural equation model with entrepreneurship and entrepreneurial intention as a parameter. Iinnovation and risk-taking have an impact on entrepreneurship by taking entrepreneurship education as a parameter. Initiative had an effect on the entrepreneurial intention a business, regardless of entrepreneurship education. In a number of studies, university entrepreneurship education has had an impact on the entrepreneurial intention. It should be changed to entrepreneurship education that combines theory and practice. Entrepreneurship education should be transformed into continuous and field-oriented education.

• Korean Journal of Ecology and Environment
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• v.51 no.1
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• pp.124-134
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• 2018

We analyzed research topics, temporal distribution of field sites, and researcher network of 1,508 limnology publications in the Korean Journal of Limnology (1968~2012) and the Korean Journal of Ecology and Environment (2013~2017). We found that water quality and sediment, phytoplankton, invertebrates, and fish were major subjects during the study periods. Survey of flora and fauna and physiological experiment of freshwater species were the largest subjects during 1970~80s, while other subjects including production, behavior, modeling, and ecological assessment have been rapidly increased since the 1990s. Most of the biological taxa equally studied lotic and lentic system, however, invertebrates and fish related studies more focused on the lotic system. Spatially, the field site of Korean limnology studies was found to be concentrated in main river channels runs through urban areas and artificial lakes than preserved natural areas. Freshwater system, located at the elevation range of 301~400 m (upstream of main channels), had the lowest number of field sites. Collaboration among researchers and different institution types have been steadily increased and expanded as the number of publications increased.

• Horticultural Science & Technology
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• v.28 no.4
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• pp.701-707
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• 2010

To analyze the effectiveness of horticultural therapy reported in research papers, a meta-analysis was carried out with 108 of 377 Korean and overseas research papers on horticultural therapy from 1985 to February 2009 (196 Korean dissertations, 113 Korean journal articles, 5 overseas dissertations, and 63 overseas journal articles). The results revealed a large effect size of 0.71. The effectiveness according to the type, age and number of participants were also analyzed. The therapy was most effective in children, and it was more beneficial for children with special needs and elderly people affected by dementia than for the typical population. The greatest effect was found with group sizes of five people or less, and when carried out by researchers from departments related to horticultural therapy than by researchers from unrelated fields of study. The most effective horticultural therapy programs involved floral decorations; and participants who took part in 21 to 30 sessions or at least 31 sessions benefited the most. Among the main effects of short-term horticultural therapy are cognitive, social, physical and emotional; the greatest effect was observed in the physical domain.

• Journal of Animal Science and Technology
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• v.62 no.1
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• pp.31-42
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• 2020

The aim of this study was to investigate the effects of 3-nitrooxypropanol (NOP) on gas production, rumen fermentation, and animal performances depending on animal type using a meta-analysis approach. A database consisted of data from 14 studies, 18 experiments and 55 treatments. The supplementation of NOP linearly decreased methane (CH₄) emissions [g/kg dry matter intake (DMI)] regardless of animal type and length of experimental period (beef, p < 0.0001, R² = 0.797; dairy, p = 0.0003, R² = 0.916; and long term, p < 0.0001, R² = 0.910). The total volatile fatty acids (VFA) concentration and the proportion of acetate, based on beef cattle database, were significantly decreased with increasing NOP supplementation (p = 0.0015, R² = 0.804 and p = 0.0003, R² = 0.918), whereas other individual VFAs was increased. Based on the dairy database, increasing levels of NOP supplementation linearly decreased proportion of acetate (p = 0.0284, R² = 0.769) and increased that of valerate (p = 0.0340, R² = 0.522), regardless of significant change on other individual VFAs. In animal performances, the DMI, from beef cattle database, tended to decrease when the levels of NOP supplementation increased (p = 0.0574, R² = 0.170), whereas there was no significant change on DMI from dairy cattle database. The NOP supplementation tended to decrease milk yield (p = 0.0606, R² = 0.381) and increase milk fat and milk protein (p = 0.0861, R² = 0.321, p = 0.0838, R² = 0.322). NOP is a viable candidate as a feed additive because of its CH₄ mitigation effects, regardless of animal type and experiment period, without adverse effects on animal performances.

• Korean journal of communication and information
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• v.63
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• pp.76-100
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• 2013

This work is for redefining of cultural diversity and suggesting measurement frame by casting light on changing cultural environment according to evolution of digital convergence media. So far, most of studies tend to confuse at using media diversity and cultural diversity and resultingly the concept of cultural diversity is not founded right yet. In communications field, there is a limit to measure cultural diversity which is substantive content because analysis of media diversity is mainly focused on financial measuring and quantitation. Therefore we define digital convergence media culture as metaculture here for analysis of cultural diversity. Additionally, we catagorize and analysis cultural diversity based on this metaculture into pluralism of media activity, diversity of cultural expression, diversity of cultural diffusion and diversity of cultural cognition. These measuration variables of the four categories are factors which can lighten aspects of cultural diversity in digital convergence media environment. Analysis of these factors of the four catagories will suggest a criterion to establish policies to protect cultural diversity. The policy of cultural diversity is to construct a cultural commune in envirnment of meta culture.

• Microbiology and Biotechnology Letters
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• v.35 no.2
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• pp.104-111
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• 2007

In this study, aniline dioxygenase genes responsible for initial catabolism of aniline in Burkholderia sp. HY1 and Delftia sp. HY99 were cloned and the amino acid sequences were comparatively analyzed, which already have been reported as bacteria utilizing aniline as a sole source of carbon and nitrogen, B. sp. HY1 was found to have at least a plasmid, and the plasmld-cured strain, B. sp. HY1-PC obtained using mitomycin C was tested with wild type strain to investigate whether the former maintained the degradability for aniline. This proved that the aniline oxygenase gene from B. sp. HY1 was located in chromosomal DNA, not in plasmid DNA. Aniline dioxygenase small subunits from B. sp. HY1 and D. sp. HY99 were found, based on 146 amino acids, to share 79% similarity. Notably, ado2 genes from B. sp. HY1 and D. sp. HY99 which were found to be terminal dioxygenase of aniline dioxygenase small subunit showed 99% similarity in the deduced amino acid sequences with tdnA2 of Frateuria sp. ANA-18 and danA2 of D. sp. AN3, respectively. Besides, enzyme assay and amino acid sequence analysis of catechol dioxygenase supported the previous report that B. sp. HY1 might occupy ortho-cleavage pathway using catechol 1,2-dioxygenase, while D. sp. HY99 might occupy catechol 2,3-dioxygenase for meta-cleavage pathway.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.6
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• pp.137-143
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• 2015

A delay-line type time-to-digital converter (TDC) implemented in a field-programmable gate array (FPGA) is most widely owing due to its simple structure and high conversion rate. However, the delay-line type TDC suffers from nonlinearity error caused by the long delay-line because its time interval measurement range is determined by the length of the used delay line. In this study, a new TDC structure with a shorter delay line by taking a pulse train as an input is proposed for improved time accuracy and efficient use of resources. The proposed TDC utilizes a pulse-train with four transitions and a transition state detector that identifies the used transition among four transitions and prevents the meta-stable state without a synchronizer. With 72 delay cells, the measured resolution and maximum non-linearity were 20.53 ps, and 1.46 LSB, respectively, and the time interval measurement range was 5070 ps which was enhanced by approximately 343 % compared to the conventional delay-line type TDC.

• Journal of Digital Convergence
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• v.13 no.9
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• pp.191-199
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• 2015

The Journal of Digital Policy & Management. This space is for the abstract of your study in English. In this paper, we propose a u-convergence Tourist Information 3.0 System using Flow Theory. It generates a sense of u-challenge and u-skills to maximize the enjoyment of tourists is u-convergence Tourist Information 3.0. This is a challenge to good sense and adjust the rating of the Convergence Contents information quality(CCIQ) analysis to maximize the enjoyment of tourists. Convergence Contents information quality(CCIQ) of the conductive continuity of the content closed antecedents u-conductive sense, the tourist synchronization adequacy may generate data that can be analyzed. Content Information Quality of rating is the leading factor in the ability of the u-skill mastery of tourists, can generate data availability. The result is to create a meta-model is referred to as content information to reach the best quality maximize enjoyment. Design a sense of u-challenge the skill of the information quality of the tourist information content has the advantage of being able to identify the data formation has the pleasure of tourists. By applying to future national competent standard it is expected to maximize the enjoyment of the job.