• Title/Summary/Keyword: Meta study

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Loss of Potential Biomarker Proteins Associated with Abundant Proteins during Abundant Protein Removal in Sample Pretreatment

  • Shin, Jihoon;Lee, Jinwook;Cho, Wonryeon
    • Mass Spectrometry Letters
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    • v.9 no.2
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    • pp.51-55
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    • 2018
  • Capture of non-glycoproteins during lectin affinity chromatography is frequently observed, although it would seem to be anomalous. In actuality, lectin affinity chromatography works at post-translational modification (PTM) sites on a glycoprotein which is not involved in protein-protein interactions (PPIs). In this study, serial affinity column set (SACS) using lectins followed by proteomics methods was used to identify PPI mechanisms of captured proteins in human plasma. MetaCore, STRING, Ingenuity Pathway Analysis (IPA), and IntAct were individually used to elucidate the interactions of the identified abundant proteins and to obtain the corresponding interaction maps. The abundant non-glycoproteins were captured with the binding to the selected glycoproteins. Therefore, depletion process in sample pretreatment for abundant protein removal should be considered with more caution because it may lose precious disease-related low abundant proteins through PPIs of the removed abundant proteins in human plasma during the depletion process in biomarker discovery. Glycoproteins bearing specific glycans are frequently associated with cancer and can be specifically isolated by lectin affinity chromatography. Therefore, SACS using Lycopersicon esculentum lectin (LEL) can also be used to study disease interactomes.

Comparative Study of Discovery Services (디스커버리 서비스의 비교 분석)

  • Kwak, Seung-Jin;Shin, Jae-Min;Kim, Bo-Young
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.27 no.4
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    • pp.5-20
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    • 2016
  • Discovery service has as its object to cope with the user to take advantage of the collection of the library as possible to index and search, one step further, the interface by more efficiently to the user's information needs. Discovery service has features such as providing a ranking and navigation services to subdivide the search results by facet results along the suitability and visually rich display, suggestions, recommendations associated resources. In this study introduces the status of discovery services such as discovery service products, usage status, and features, and compares and analyzes the use agencies, content status, main functions, and features of the three discovery services used in Korea library.

Analysis on the Media Content Research Trends in Media Convergence Era Based on Intellectual Information Technology (지능정보기술 기반 미디어 컨버전스 시대의 콘텐츠 연구경향 분석)

  • Jeon, Gyongran;Kim, Young-Chul
    • Journal of Korea Game Society
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    • v.20 no.2
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    • pp.113-122
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    • 2020
  • This study is the research tendency(2016~2019) on the content and the intelligent information technology. After the IIT emerged as a social topic, related research increased, and interest in VR and AR was the highest. In games, more research has been done on VR and AR. In the case of big data technology, it was a tendency to pay attention to the study of movie contents. Many studies have attempted a technological approach to IIT. With regard to artificial intelligence technology, there were differences by technology and content area, mainly viewed from a legal and institutional perspective.

Concentration of metal in herbal drugs -in crude, remnant after boiling and decoction of herbal drugs- (한약재에 포함된 금속의 전탕 전과 후의 농도변화연구 -첩약 / 다린 찌꺼기 / 탕약을 중심으로-)

  • 이선동;박해모;이장천;국윤범
    • The Journal of Korean Medicine
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    • v.24 no.2
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    • pp.59-65
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    • 2003
  • This study was conducted to analyze metal concentration changes following processing steps for crude, remnant after boiling, and decoction of Korea herbal drugs. We measured meta.! concentration from 20 random patients who visited Oriental medical clinics for treatment of several diseases through normal action. The results obtained were as below: First, in the study to acknowledge quality control between Korean Lab and Harvard Lab in the US, 20 equal herbal samples resulted in the same values, so we confirmed the precision of measurement results from both labs. Second, hazardous metal mean concentration in crude, remnant after boiling, and decoction of herbal drugs were $32.5{\mu\textrm{g}}/22.1{\mu\textrm{g}}/8.8{\mu\textrm{g}}$ for As, $0.0{\mu\textrm{g}}/0.0{\mu\textrm{g}}/0.0{\mu\textrm{g}}$ for Cd, $1.0{\mu\textrm{g}}/0.0{\mu\textrm{g}}/0.0{\mu\textrm{g}}$ for Hg and $5416.3{\mu\textrm{g}}/3639.6{\mu\textrm{g}}/1002.6{\mu\textrm{g}}$ for Pb, respectively. These metal concentrations decreased 72.9-100.0% compared to crude status. The same trend was also visible in the other essential elements. From reviewing these results, we could carefully conclude that decoction had the least amount of metal concentration and is the optimal way to intake herbal drugs.

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A Study on PET Adsorption Property of NIR Dye Using Swelling Agents (Swelling agent를 이용한 근적외선 흡수 유기색소의 polyester 흡착)

  • Kwon, Su Hyeon;Choi, Jae Hong
    • Textile Coloration and Finishing
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    • v.30 no.1
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    • pp.20-28
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    • 2018
  • The near infrared ray camouflage fabric has a near infrared ray reluctance similar to the surrounding environment and has a camouflage effect on the surrounding environment. Synthetic fibers used in military uniforms are difficult to have gastrointestinal function as general commercial dyes, unlike cellulose fibers, which use some commercial vat dyes to impart infrared gastrointestinal function. In this study, we optimized the adsorption pH, temperature and time for NIR dye application for polyester fabrics, and established the optimum concentration for the evaluation of adsorption build-up characteristics. In addition, it is difficult to adsorb it since the polyester material has a dense crystal structure and the NIR dye is bulky. Therefore, a swelling agent used for dyeing meta-aramid fibers with high Tg and high crystallinity was introduced as a separate preparation to increase the affinity to polyester, which is a hydrophobic fiber, to thereby obtain an excellent adsorption rate. As a result of comparing before and after using swelling agent, the adsorption rate difference was 10 times or more when compared with before.

A Study on the Elements of Indexing and Abstracting on the World Wide Web (웹 정보자원의 색인과 초록 요소에 관한 연구)

  • Choi Jae-Hwang
    • Journal of the Korean Society for Library and Information Science
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    • v.33 no.1
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    • pp.113-128
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    • 1999
  • Although traditional printed materials m indexed and abstracted by human beings with tools like thesaurus or controlled vocabulary, information resources on World Wide Web(WWW) are automatically indexed and abstracted without human beings efforts. It would be useful to investigate what major differences are in processes and in elements of indexing and abstracting between traditional printed materials and information resources on WWW. After discussing how WWW search engines work, six major WWW search engines were chosen for this study. Then, 17 indexing elements, 11 abstracting elements, and 2 meta elements were examined. Overall trends and issues for the future development of indexing and abstracting on WWW are also discussed.

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A Study on the Data Model of Topographic-Cadastral Map (지형.지번도의 데이터모델에 관한 연구)

  • 최윤수;고준환;서용운;이석용
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.19 no.1
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    • pp.85-93
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    • 2001
  • Digital mapping project of topographic map was conducted according to the master plan for the development of the National Geographic Information System, to manage national geo-spatial information efficiently in rapidly changing information technology society. It needed to correct and supplement digital map because of time pressure, sudden urbanization and users'need. In this study, after the framework data of thematic map was given a definition based on data model of National Base Map, data model of topographic-cadastral map was presented. Also data format and meta data suited to presented data model of topographic-cadastral map were presented so that they could be used in various fields.

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Analysis of the Effects of Tai Chi on Muscle Strength and Flexibility (타이치 운동의 근력 및 유연성의 효과에 관한 논문분석)

  • Choi, Jung-Hyun;Lee, Eun-Ok;Lee, Hea-Young;Eun, Young
    • Journal of muscle and joint health
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    • v.12 no.1
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    • pp.69-80
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    • 2005
  • Purpose: The purpose of this study was to analyse the effects of Tai Chi on the muscle strength and flexibility. Method: 10 articles from Medline search of foreign journals(1981-2003) and 4 from Korean nursing journals (1981-2003) were surveyed. The research are analyzed according to research design, subjects, and dependent variables. Results: Research on Tai Chi Exercise increased rapidly in the 1990's. The experimental research design was more reported than the comparative design. The experimental design included; 21.4% one group pre-posttest design, 35.7% quasi-experimental design and 28.6% randomized design. Out of the subjects; 64.4% of papers were healthy older people, and 35.6% of papers were patients with osteoarthritis or rheumatoid arthritis. Style of Tai Chi was mostly used Yang or Sun form. Muscle strength was usually measured at lower extremity or grip strength. Classical Yang style or Long form was more effective to improve muscle strength. 75% of papers were significantly improvement in grip strength and 71.4% of papers in flexibility. Conclusion: To properly study the positive effects of Tai Chi exercise, it is suggested that meta analysis needs to be done to integrate the various results.

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The Determinants of Management Information Systems Effectiveness in Small- and Medium-Sized Enterprises

  • LE, Quang Bon;NGUYEN, Minh Dat;BUI, Van Can;DANG, Thi Mai Huong
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.8
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    • pp.567-576
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    • 2020
  • This study develops a mediating model to explore the relationships between organizational characteristics, manager's knowledge, management commitment, user involvement, information quality, and management information system effectiveness in small- and medium-sized enterprises in Vietnam. Adapting scales from previous research, the authors designed questionnaires, which they distributed to respondents in Vietnamese small- and medium-sized enterprises. Also, by employing a meta-analytic path analysis throughout structural equation modelling (SEM) with sample of 356 respondents, authors indicate that organizational characteristics are directly related to management information systems effectiveness. Moreover, manager's knowledge, user involvement, and information quality show their important roles in the increase of management information system effectiveness, yet management commitment does not indicate a similar role in the growth of management information system effectiveness. Bootstrapping is utilized to discover the meditating role of information quality, illustrating that quality information mediates the linkages between user involvement, organizational characteristics, and management information systems. However, the mediating role of information quality in the relationship between management commitment, manager's knowledge, and management information systems is not significant. This study contributes to the management information system literature as well as to enhance MIS effects in small and medium-sized enterprises.

A Study on the Rhetorical Expression of Scene Design in Theatre - Focused on the Case Study of the Scene Design of King Lear - (연극 무대 공간디자인에 대한 수사학적 연구 - 세익스피어 작 "리어왕"의 무대 공간디자인 사례연구를 중심으로 -)

  • Ahn, Ju-Young
    • Korean Institute of Interior Design Journal
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    • v.16 no.3 s.62
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    • pp.21-29
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    • 2007
  • The communication in a play has a dual structure, which is composed of the communications within a play and in a theatre space. This research focuses on the scene design that creates the background or the theme of a play and communicates theme of a play to the audience. A scene design of a theatre has meta-linguistic aspects, which is the image or mood as the theme of a play. The scene design is composed of various design elements of space and objects as the properties of a play. Design elements and the objects are the design languages in various form; plane, three-dimensional, multi-dimensional form. These design languages have the significant meanings as signs like human language. The play works chooses the rhetorical expression to arouse the audience's sympathy. The scene design is completed with rhetorical expression for communication in theatre too. This research defines the category of meanings that design elements of scene design can create and the rhetorical expression of the scene design language. King Lear directed by Robert G. Anderson was analyzed with the category of design elements as a sign and the pattern of the rhetorical expression. The scene design for a play is completed effectively by the rhetorical expression of design elements as the design language for the communication with the audience in theatre.