• Title/Summary/Keyword: Meta analysis

Search Result 2,591, Processing Time 0.03 seconds

Effects of Exercise-Based Intervention Before and After Lung Cancer Surgery: A systematic review in pubmed database (허파암 수술 전과 후에 적용한 운동의 효과: PubMed 내 연구에 대한 체계적 문헌고찰)

  • Boram Oh;Heesu Kim;Sookyoung Park
    • Journal of The Korean Society of Integrative Medicine
    • /
    • v.11 no.2
    • /
    • pp.23-35
    • /
    • 2023
  • Purpose : Lung cancer induces a decrease in physical activity and a deterioration of respiratory ability. Exercise is an effective treatment to reduce side effects of anti-cancer treatments, also influence the survival and successful rehabilitation in lung cancer patients. However, there is insufficient evidence to show which period is the most effective to apply exercise for lung cancer patients. Therefore, this study was conducted to evaluate the efficacy of exercise-based interventions before and after surgery. Methods : Clinical trials (CTs) and randomized controlled trials (RCTs) reported in PubMed database were investigated. The trials investigated in this study were published for 10 years before August 20, 2022. The risk of bias was judged according to the Cochrane guideline. The materials included in this meta-analysis were 6-minute walk test (6MWT), pulmonary function, and quality of life (QOL). Results : 1 CT and 9 RCTs were selected in current study. In the meta-analysis, exercise increased 6MWT in preoperation (mean difference [MD] 29.49; 95 % confidence interval [CI] .99 to 57.99; p=.04; I2=0 %), 3 months postoperation (MD 54.97; 95 % CI 31.85 to 78.09; p<.001; I2=45 %) and 6 months postoperation (MD 85.59; 95 % CI 45.06 to 126.12; p<.001; I2=47 %). Exercise, also enhanced the lung function such as FEV1/FVC (%) in postoperation (MD 7.64; 95 % CI 6.26 to 9.02; p<.001; I2=19 %). Additionally, exercise improved QOL, such as preoperative EORTC-QLQ-C30-LC13 in mental function (MD 3.21; 95 % CI .64 to 5.79; p=.01; I2=0 %) and postoperative SF-36 in mental component summary (MD 9.24; 95 % CI 4.94 to 13.54; p<.001; I2=0%). Conclusion : These results indicate that exercise-based intervention can elevate the ability to exercise and the mental componentof QOL within 3 months.

Effect of Herbal Medicines on Preventing Restenosis After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis of Randomized Controlled Trials (경피적 관상동맥중재술 후 재협착 예방에 대한 한약의 효과 : 무작위배정 대조군 임상연구에 대한 체계적 문헌고찰 및 메타분석)

  • Nayeon Hur;Subin Ahn;Hongjun Kim;Insoo Jang
    • The Journal of Internal Korean Medicine
    • /
    • v.44 no.3
    • /
    • pp.387-401
    • /
    • 2023
  • Objective: This study was conducted to investigate the preventive effect of herbal medicines on restenosis after percutaneous coronary intervention (PCI) by reviewing randomized controlled trials (RCTs). Methods: RCTs were searched for herbal medicine treatment after PCI using eight online databases (PubMed, CNKI, Wanfang, J-STAGE, OASIS, ScienceON, KTKP, and KISS). Studies that confirmed restenosis through coronary angiography at follow-up were selected according to the inclusion and exclusion criteria. The primary outcome was the restenosis rate, and the secondary outcome was the angina recurrence rate. Data were extracted from the final selected studies according to the research methodology and then analyzed with Review Manager 5.4.1. Study quality was assessed using Cochrane's risk-of-bias (RoB) tool. Results: Of the 252 papers obtained through the primary search, nine studies that met the selection criteria were finally selected. In these nine studies, herbal medicine combined with western medicine was used for the experimental group, and western medicine treatment was used alone for the control group. The meta-analysis result revealed that the restenosis rate and angina recurrence rate were significantly lower in the experimental group than in the control group (RR=0.34, 95% CI: 0.22-0.53, p<0.00001, I2=0% and RR=0.47, 95% CI: 0.29-0.78, p=0.004, I2=0%, respectively). Furthermore, the quality of studies assessed by Cochrane's RoB was low. Conclusions: This study showed that the combined treatment of herbal medicine and western medicine was effective in preventing restenosis and angina after PCI. As the number of papers included in this study was small, a large number of high-quality clinical studies should be considered in the future.

A Meta-Analysis of youth leadership related variables: focus on implication of leadership selection by admission officer system (청소년 리더십 관련변인 메타분석: 입학사정관 리더십 전형에의 시사점 도출을 중심으로)

  • Kim, Yee Jee;Lee, Ki Hak
    • Korean Journal of School Psychology
    • /
    • v.8 no.1
    • /
    • pp.43-59
    • /
    • 2011
  • The purposes of this research are: to observe the related variables; to compare the effect size; and make suggestions for leadership selection by admission officer system based on the results from the observation and comparison through meta analysis. The research questions crafted in order to achieve the purpose are as follows. First, what kind of variables were discussed in the previous studies? and can these variables be classified as the categories of the existing studies? Second, how are the effect sizes of the youth leadership related variable groups? Third, how are the effect sizes of sub factors of the related variable groups? The specific results of this research are as follows. First, youth leadership related variables can be classified as demographic, organization-activities, home environment and sociopsychological variables. Second, sociopshycological variable group shows the largest effect size. Third, among the sub factors, self esteems (ES=1.3231) and degree of satisfaction for life (ES=1.1737) show two largest effect sizes. In conclusion, based on the result of the research, this research suggests an alternative for a method to select students through admission counseling leadership selection system.

Relationships between dietary rumen-protected lysine and methionine with the lactational performance of dairy cows - A meta-analysis

  • Agung Irawan;Ahmad Sofyan;Teguh Wahyono;Muhammad Ainsyar Harahap;Andi Febrisiantosa;Awistaros Angger Sakti;Hendra Herdian;Anuraga Jayanegara
    • Animal Bioscience
    • /
    • v.36 no.11
    • /
    • pp.1666-1684
    • /
    • 2023
  • Objective: Our objective was to examine the relationships of supplemental rumen-protected lysine (RPL) or lysine + methionine (RPLM) on lactational performance, plasma amino acids (AA) concentration, and nitrogen use efficiency of lactating dairy cows by using a meta-analysis approach. Methods: A total of 56 articles comprising 77 experiments with either RPL or RPLM supplementation were selected and analyzed using a mixed model methodology by considering the treatments and other potential covariates as fixed effects and different experiments as random effects. Results: In early lactating cows, milk yield was linearly increased by RPL (β1 = 0.013; p<0.001) and RPLM (β1 = 0.014; p<0.028) but 3.5% fat-corrected milk (FCM) and energy-corrected milk (ECM) (kg/d) was increased by only RPL. RPL and RPLM did not affect dry matter intake (DMI) but positively increased (p<0.05) dairy efficiency (Milk yield/DMI and ECM/DMI). As a percentage, milk fat, protein, and lactose were unchanged by RPL or RPLM but the yield of all components was increased (p<0.05) by feeding RPL while only milk protein was increased by feeding RPLM. Plasma Lys concentration was linearly increased (p<0.05) with increasing supplemental RPL while plasma Met increased (p<0.05) by RPLM supplementation. The increase in plasma Lys had a strong linear relationship (R2 = 0.693 in the RPL dataset and R2 = 0.769 in the RPLM dataset) on milk protein synthesis (g/d) during early lactation. Nitrogen metabolism parameters were not affected by feeding RPL or RPLM, either top-dress or when supplemented to deficient diets. Lactation performance did not differ between AA-deficient or AA-adequate diets in response to RPL or RPLM supplementation. Conclusion: RPL or RPLM showed a positive linear relationship on the lactational performance of dairy cows whereas greater improvement effects were observed during early lactation. Supplementing RPL or RPLM is recommended on deficient-AA diet but not on adequate-AA diet.

The Effects of Music Interventions on High-risk Neonates in NICUs: Systematic Review and Meta-analysis (신생아집중치료실 고위험 신생아 대상 음악중재연구에 대한 체계적 문헌고찰 및 메타분석)

  • Kim, Hye Rang;Park, Hye Young
    • Journal of Music and Human Behavior
    • /
    • v.20 no.2
    • /
    • pp.115-142
    • /
    • 2023
  • The purpose of this study was to analyze and evaluate music intervention research conducted with high-risk neonates in NICUs in both domestic and international settings. Seventeen music intervention studies were identified, and their characteristics, including type of music, music provider, and treatment frequency, and outcomes (i.e., neonatal vital signs) were reviewed and analyzed along with meta-analysis. For music interventions targeting high-risk neonates in NICUs, the effect sizes of the neonates' vital signs were classified as either medium or large. In addition, larger effect sizes were associated with a combination of live and recorded music, nonmusical therapists as the music providers, and treatment frequency of one to five sessions per week. These research findings verify the clinical value of music for high-risk neonates and provide insights into the selection of music elements, music delivery methods, and music providers in NICU music interventions.

A Study on the Naming Rules of Metadata based on Ontology (온톨로지 기반 메타데이터 명명 규칙에 관한 연구)

  • Ko, Young-Man;Seo, Tae-Sul
    • Journal of the Korean Society for information Management
    • /
    • v.22 no.4 s.58
    • /
    • pp.97-109
    • /
    • 2005
  • To build the consistency among different metadata systems and to increase the interoperability of that systems even among different domains, naming rules and glossaries for the data elements are necessary. This study provides discussion of naming and identification of the data element concept, data element, conceptual domain, value domain, and its meta model. This study also describes example naming conventions based on ontology derived from the combination with object, properties, and representation of data elements. The naming principles and rules described in this study use I-R analysis, DC metadata set, and SHOE 1.0 as an example of the scientific documents. This study would be a guideline to build the naming rules of metadata based on ontology in various domains.

A Study on Availability Agent from UML Products (I) (UML 산출물로부터의 Agent 사용가능성에 관한 연구 (1))

  • Han, Hyun-Gaun;Yun, Young-Woo
    • Journal of the Korea Computer Industry Society
    • /
    • v.5 no.9
    • /
    • pp.1055-1062
    • /
    • 2004
  • Unified Modeling Language (UML) is a standard language for specifying, visualizing, constructing, and documenting the artifacts of software systems. On the other hand, XML, which is a meta-language, provides meta-data types for representing and string objects. It make software development easy because it can represent various information and share information about the software analysis and design between developers, In this paper, we apply BitWiz, one of automated software generation systems, to a bid application and analyse this in UML point of view. Also, we briefly introduce an XML documentation from UML products and a verification method of XML documents from UML products.

  • PDF

RASSF1A Gene Methylation is Associated with Nasopharyngeal Carcinoma Risk in Chinese

  • Wu, Kun;Xu, Xiao-Ning;Chen, Yu;Pu, Xiao-Lin;Wang, Bo-Yuan;Tang, Xiao-Dan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.6
    • /
    • pp.2283-2287
    • /
    • 2015
  • In order to explore the association between RASSF1A methylation and nasopharyngeal carcinoma (NPC) risk of Chinese, we carried out a meta-analysis with searches of PubMed, Web of Science, ProQest and Medline databases. Ultimately, 14 articles were identified and analysised using R Software (R version 3.1.2) including meta packages. Overall, we found a significant relationship between RASSF1A methylation and NPC risk (OR 30.7; 95 % CI, 16.71~56.23; z=11.0591; p<0.0001) in a fixed effects model and (OR 32.1; 95% CI, 14.27~72.01; z=8.3984; p<0.0001) in a random effects model pooled. In tissue and NP brushings groups, similar results were found. Hence, our study identified a strong association between RASSF1A methylation and NPC and highlighted a promising potential for RASSF1A methylation in NPC risk prediction of Chinese.

A Study on the Game Criticism: Meta-analytical Approach to Game Critiques (게임비평에 대한 연구 : 게임비평 텍스트의 메타분석적 접근)

  • Jeon, Gyongran
    • Journal of Korea Game Society
    • /
    • v.13 no.3
    • /
    • pp.19-30
    • /
    • 2013
  • Digital games have become a major part of the modern popular culture, but little attention has been paid to understanding the textuality of games and what the game texts have the cultural meanings. As the games develop, however, the academic and journalistic game critiques and reviews that try to understand and to deconstruct the game texts are on the rise. This study explores how the game criticism characterizes the game texts, creates and shapes the understanding of games. The finding shows that game criticism is rich and varied in terms of themes and approaches covered, more generally, games criticism can also help preserve game history by focusing on the distinctive game textuality, forms and meanings, and by contextualizing the links and cultural meanings that exist between games and between games and the cultural context.

Analysis of Xe Plasma by LAS (레이저 흡수법을 이용한 제논 플라즈마 분석)

  • Yang, Jong-Kyung;Her, In-Sung;Lee, Jong-Chan;Choi, Yong-Sung;Park, Dae-Hee
    • Proceedings of the KIEE Conference
    • /
    • 2005.11a
    • /
    • pp.220-222
    • /
    • 2005
  • We can classify two cases in a way to observe an atom of gas state or a molecule using the laser. First case is way to use dispersion phenomenon like Rayleigh scattering, Thomson scattering, Mie scattering, Raman Scattering. And Second case is a way to use change phenomenon like a LAS (Laser Absorption Spectroscopy), LIF (Laser Induced Fluorescent). In this paper, we have measured the meta-stable density and the distribution by using a LAS method in Xe discharge lamp. The laser absorption spectroscopy (LAS) is useful to investigate the behavior of such species. The xenon atoms in the $1S_4$ and $1S_5$ generate excited $Xe^*$(147nm) and $Xe_{2}^*$(173nm) dimers in Xe plasma. It is found that the intensity of VUV 147nm emission is proportional to that of the IR 828nm emission, and the VUV 173nm emission is roughly proportional to that of the IR 823nm emission. The laser is used CW laser that consist of AlGaAs semiconductor and energy level is used 823.16nm wavelength. We measured signal of monochrometer from the lamp center while will change a discharge electric current by 6mA in 3mA and calculated meta-stable state density of a xenon atom through a measured value.

  • PDF