• Title/Summary/Keyword: Met

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Measurement and Decomposition of Socioeconomic Inequality in Metabolic Syndrome: A Cross-sectional Analysis of the RaNCD Cohort Study in the West of Iran

  • Moslem Soofi;Farid Najafi;Shahin Soltani;Behzad Karamimatin
    • Journal of Preventive Medicine and Public Health
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    • v.56 no.1
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    • pp.50-58
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    • 2023
  • Objectives: Socioeconomic inequality in metabolic syndrome (MetS) remains poorly understood in Iran. The present study examined the extent of the socioeconomic inequalities in MetS and quantified the contribution of its determinants to explain the observed inequality, with a focus on middle-aged adults in Iran. Methods: This cross-sectional study used data from the Ravansar Non-Communicable Disease cohort study. A sample of 9975 middleaged adults aged 35-65 years was analyzed. MetS was assessed based on the International Diabetes Federation definition. Principal component analysis was used to construct socioeconomic status (SES). The Wagstaff normalized concentration index (CIn) was employed to measure the magnitude of socioeconomic inequalities in MetS. Decomposition analysis was performed to identify and calculate the contribution of the MetS inequality determinants. Results: The proportion of MetS in the sample was 41.1%. The CIn of having MetS was 0.043 (95% confidence interval, 0.020 to 0.066), indicating that MetS was more concentrated among individuals with high SES. The main contributors to the observed inequality in MetS were SES (72.0%), residence (rural or urban, 46.9%), and physical activity (31.5%). Conclusions: Our findings indicated a pro-poor inequality in MetS among Iranian middle-aged adults. These results highlight the importance of persuading middle-aged adults to be physically active, particularly those in an urban setting. In addition to targeting physically inactive individuals and those with low levels of education, policy interventions aimed at mitigating socioeconomic inequality in MetS should increase the focus on high-SES individuals and the urban population.

Higher concentrations of folic acid reduced the dietary requirements of supplemental methionine for commercial broilers

  • S. V. Rama Rao;M. V. L. N. Raju;D. Nagalakshmi;T. Srilatha;S. S. Paul;B. Prakash;A. Kannan
    • Animal Bioscience
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    • v.37 no.5
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    • pp.875-882
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    • 2024
  • Objective: An experiment was conducted to study the effect of supplementing DL methionine (DL Met) at graded concentrations on performance, carcass variables, immune responses and antioxidant variables in broiler chicken fed folic acid (FA) fortified (4 mg/kg) low-methionine diet. Methods: A basal diet (BD) without supplemental DL Met, but with higher level (4 mg/kg) of FA and a control diet (CD) with the recommended concentration of methionine (Met) were prepared. The BD was supplemented with DL Met at graded concentrations (0%, 10%, 20%, 30%, 40%, and 50% supplemental DL Met of CD). Each diet was fed ad libitum to 10 replicates of 5 broiler male chicks in each from 1 to 42 d of age. Results: Body weight gain (BWG) reduced, and feed conversion ratio (FCR) increased in broilers fed low-Met BD. At 30% and 20% inclusion of DL met, the BWG and FCR, respectively were similar to those fed the CD. Similarly, supplementation of 10% DL Met to the BD significantly increased ready to cook meat yield and breast meat weight, which were similar to those of the CD fed broilers. Lipid peroxidation reduced, the activity of antioxidant enzymes (GSHPx and GSHRx) in serum increased and lymphocyte proliferation increased with increased supplemental DL Met level in the BD. The concentrations of total protein and albumin in serum increased with DL Met supplementation to the BD. Conclusion: Based on the data, it can be concluded that supplemental Met can be reduced to less than 50% in broiler chicken diets (4.40, 3.94, and 3.39 g/kg, respectively in pre-starter, starter and finisher phases) containing 4 mg/kg FA.

Effects of Different Sources of Dietary Chromium and Copper on Growth Performances, Nutrients Digestibility, Fecal Cr, Cu and Zn Excretion in Growing Pigs (크롬과 구리의 형태별 병용급여가 육성돈의 육성성적, 소화율 및 분의 Cr, Cu, Zn 배출량에 미치는 영향 미치는 영향)

  • Park, Jeoung-Keum;Kim, Jin-Woong;Yoo, Young-Beom;Lee, Jun-Yeop;Ohh, Sang-Jip
    • Journal of Animal Science and Technology
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    • v.50 no.3
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    • pp.355-362
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    • 2008
  • This study was carried out to evaluate effects of either organic or inorganic sources of both chromium and copper on growth performances, nutrients digestibility and fecal Cr, Cu, and Zn excretion in growing pigs. A total of 36 growing pigs((Landrace×Yorkshire)×Duroc, weighing 61.2kg in average) were allotted to 4 treatments with 3 replicates and 3 pigs per replicate. Four treatments were designated by supplemental sources of both chromium and copper as follows: ①200ppb Cr as Cr-methionine chelate(CrMet) and 200ppm Cuas copper methionine chelate(CuMet), ②200ppb Cr as CrMet and 200ppm Cu as copper sulfate(CuSO4), ③200ppb Cr as chromium chloride(CrCl3) and 200ppm Cu as CuMet, ④200ppb Cr as CrCl3 and 200ppm Cu as CuSO4. Growth performance was highest(p<0.05) in CrMet and CuMet supplemented diet treatment. Nutrients digestibility of diets was lowest(p<0.05) in CrMet and CuSO4 supplemented diet treatment, and highest(p<0.05) in CrMet and CuMet supplemented diet treatment. Fecal copper, zinc and chromium excretion was highest(p<0.05) in CrCl3 and CuSO4 supplementation treatment and lowest(p<0.05) in CrMet and CuMet supplementation treatment. This study showed a relatively high degree of utilization of Cr and Cu as well as Zn by supplementation of CrMet and CuMet compared with those of the inorganic sources.

Comparative analysis of energy intake and physical activity according to household type and presence of metabolic syndrome in middle-aged men based on data from the 7th Korea national health and nutrition examination survey (KNHANES) (2016-2018)

  • Park, Jonghoon;Park, Yeonhee;Lee, Youngjun;Lee, Jungwoo;Lee, Seunghee;Shin, Chulho;Sung, Eun-Sook
    • Korean Journal of Exercise Nutrition
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    • v.25 no.4
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    • pp.1-9
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    • 2021
  • [Purpose] This study analyzed data from the 7th Korean National Health and Nutrition Examination Survey (2016-2018) to compare the differences in energy intake and physical activity (PA) levels in middle-aged Korean men aged 40-59 years according to household type and the presence of metabolic syndrome (MetS). [Methods] Data from 2,266 young adults (aged >39 years and <60 years) were obtained from the KNHANES. We analyzed the differences in energy intake and PA levels according to household type and MetS. The presence or absence of MetS was determined by measuring waist circumference, blood pressure, fasting blood glucose, triglyceride, and HDL-C levels. [Results] Regarding total nutritional intake, no relationship with MetS was observed regardless of household type (interaction between MetS and household type: p = 0.875). No differences in total PA were observed between multiple- and single-person households (interaction between MetS and household type: p = 0.122). The relationship between MetS and MetS components according to nutritional intake showed that participants with a higher energy intake had a 27% lower prevalence of low high-density lipoprotein cholesterol (HDL-C) (p < 0.05) and a 36% higher prevalence of high blood pressure (p < 0.01). The relationship between MetS and MetS components according to the PA level showed significantly reduced prevalence of MetS by approximately 39%, 35%, and 43% (p < 0.01, 0.01, and 0.001) in subjects who were somewhat active, active, and very active, respectively, compared to inactivity. [Conclusion] Middle-aged men showed no difference in nutritional intake and PA between multiple- and single-person households. However, the risk of MetS was significantly higher in participants with approximately 1.5 times the energy intake compared to the group with the lowest energy intake. Moreover, higher levels of PA had a marked positive effect on the risk factors and prevalence of MetS. Therefore, we suggest that reducing the total energy intake and increasing total PA are important for preventing MetS in middle-aged men regardless of household type.

Associations between Anemia and Glomerular Filtration Rate and Albuminuria in Korean Adults by Metabolic Syndrome Status: Analysis of KNHNES V-3 Data (대한민국 성인의 대사증후군 유무에 따른 빈혈과 사구체 여과율 및 알부민뇨의 연관성: 국민건강영양조사 V-3 분석)

  • Hyun YOON
    • Korean Journal of Clinical Laboratory Science
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    • v.56 no.2
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    • pp.125-134
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    • 2024
  • The present study was conducted to explore relationships between anemia and estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) in Korean adults with or without metabolic syndrome (MetS). The data of 4,943 adults aged ≥20 years who participated in KNHNES V-3 (2012) were analyzed. In the non-MetS group, the odds ratio (OR) for anemia of those with a decreased eGFR {eGFR<60 mL/min/1.73 m2, 3.85 (95% confidence interval [CI], 2.03~7.30)} was significant as was the OR of those with decreased eGFR plus elevated uACR (eGFR<60 mL/min/1.73 m2 and uACR≥30 mg/g, 5.81 [95% CI, 2.60~13.02]). In the MetS group, ORs for anemia for those with an elevated uACR (2.18 [95% CI, 1.11~4.27]), a decreased eGFR (3.74 [95% CI, 1.11~12.55]), or a decreased eGFR plus an elevated uACR (16.79 [95% CI, 5.93~47.57]) were significant. In conclusion, in non-MetS, anemia was associated with a low eGFR, whereas in MetS, anemia was associated with a low eGFR and an elevated uACR. In addition, the OR for anemia was greatly increased when eGFR was diminished and uACR was elevated regardless of MetS and MetS status.

A Comparative Study on the Muscle Energy Technique(MET) and Stretching Exercise Effect of Hamstring Flexibility Improvement (슬괵근 유연성 증가에 대한 근에너지기법(MET)과 스트레칭 운동의 효과 비교연구)

  • Lim, Sang-Hoon;Son, Jung-Min;Prak, Dong-Su;Jeng, Su-Hyen;Kim, Soon-Joong
    • Journal of Korean Medicine Rehabilitation
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    • v.19 no.1
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    • pp.201-211
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    • 2009
  • Objectives : The purpose of this study is to evaluate the effect of Muscle Energy Technique(MET) on the Hamstring flexibility of healthy adults by comparing stretching exercise. Methods : The subjects were consisted of healthy adults(54 male, 42 female). All subject randomly assigned to the Control group, Stretching group, MET group. stretching group received hamstring stretching for 75 seconds and MET group received Hamstring MET for 75 seconds. Then subject did the sit and reach test at before treatment, right after treatment and after 10 minutes treatment. Results : 1. Result of sit and reach test according to measurement time changed, three groups were all improved and significant difference(p<0.01) was observed among three groups. 2. Compared to before treatment and right after treatment result, MET group was more significant improved(p<0.01) than stretching group. 3. Compared to before treatment and after 10 minutes result, MET group was more significant improved(p<0.01) than stretching group. Conclusions : According to above results, improvement of hamstring flexibility, MET was more effect than stretching exercise.

The Significance of c-Met and Ki-67 Expression in the Head and Neck Squamous Cell Carcinoma (두경부 편평세포암에서 c-Met 단백과 Ki-67 발현의 의의)

  • Kim, Jun;Do, Nam-Yong;Park, Jun-Hee;Choi, Ji-Yun;Lim, Sung-Chul
    • Korean Journal of Bronchoesophagology
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    • v.16 no.1
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    • pp.39-46
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    • 2010
  • Background and Objectives Various tumor markers have been studied in an attempt to evaluate and decide the optimal treatment of the patients with head and neek squamous cell carcinoma (HNSCC). A nuclear antigen Ki-67 is a proliferative marker of tumor cells in all phases of cell cycle except G0. c-met gene, the tyrosine kinase receptor for hepatocyte growth tactor, may play various roles in malignant transformation. The authors evaluated the prognostic significance of Ki-67 and c-Met in surgical specimens of HNSCC to determine the relationship with the various clinicopathological characteristics. Materials and Methods Formatin-fixed paraffin-embedded surgical specimens were obtained from 54 patients with HNSCC. Ki-67 and c-Met expressions were analyzed by immunohistochemical staning and were compared with the clinicopathological characteristics such as, pathologic differentiation, tumor stage, clinical stage and lymph node metastasis. Results Ki-67 and c-Met over-expression was detected in 66.7% and 90.7% in HNSCC. There was positive correlation of increased expression of Ki-67 with tumor stage. and clinical stage, increased expression of e-Met with tumor stage, clinical stage, and nodal status. The expression of c-Met had a significant positive relationship with Ki-67 index (p<0.05). Conclusion Therefore, Ki-67 and c-Met are useful markers of tumor progression, aggressiveness and prognosis in HNSCC.

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The Clinical Study of Muscle Energy Techniques in Elector Spinae Muscle through Meridian Electromyography on Subjects (일반인에서의 근에너지 기법 시술 전과 후의 척추기립근 경근전도 변화)

  • Choi, Jin-Seo;Ahn, Jae-Min;Park, Dong-Su;Jeong, Su-Hyeon;Kim, Soon-Joong
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.7 no.2
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    • pp.101-108
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    • 2012
  • Objectives : To evaluate the clinical utility of Muscle Energy Techniques(MET) in Elector Spinae Muscle on subjects. Methods : We compared electrical activity between a before MET and a after MET in Elector Spinae Muscle on subjects in same group(n=26) in dynamic flexion-reextension state during five seconds. We analyzed amplitudes and areas of electrical activity and Asymmetry Index(AI) and Median Edge Frequency(MEF). Results : 1. After MET in Elector Spinae Muscle on subjects were lower electrical activity than before MET in Elector Spinae Muscle on subjects but it is not a pointless observation(p<0.05). 2. AI of the after MET in Elector Spinae Muscle on subjects significantly decreased compared with before MET in Elector Spinae Muscle on subjects(p<0.05). 3. MEF of the after MET in Elector Spinae Muscle on subjects decreased compared with before MET in Elector Spinae Muscle on subjects but it is not a pointless observation(p<0.05). Conclusions : According to above results, there is clinical effect MET on subjects.

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Changes of relative impulse of foot on carrying 5 types of schoolbag during level walking (가방 휴대 방법에 따른 보행 시 발의 비례추진력 변화)

  • Pack, Soo-Jin;Kim, Min-Hee;Kim, Jin-Sang
    • The Journal of Korean Physical Therapy
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    • v.21 no.3
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    • pp.61-68
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    • 2009
  • Purpose: The purpose of this study was to analyze the changes of the relative impulse of the foot when carrying 5 types of schoolbag during level walking. Methods: Forty-four normal subjects were divided into 5 groups according to the method of carrying a bag: carrying no bag (condition 1), a backpack (condition 2), a shoulder bag (condition 3), a cross bag (condition 4) and a one-hand bag (condition 5). To evaluate the partial relative impulse, 7 areas were measured on the sole of a foot: the hallux, toe, 1st metatarsal head (Met1) and the 2nd & 3rd metatarsal heads (Met2/3), the 4th & 5th metatarsal heads (Met4/5), mid foot and heel. Repeated one-way analysis of variance (ANOVA) and independent t-tests were used to analyze the statistical data. Results: In the right foot, the relative impulses in every areas revealed no significant difference (p>0.05), however, the relative impulses at Met1, Met2/3, Met4/5 and heel were significantly different between the different conditions (p<0.05). There were significant differences on comparing the relative impulse between left and right foot within one condition, the mid foot in condition 2, as well as the hallux and Met1 in condition 3 (p<0.05). In condition 4, the toe, Met1, Met4/5 and mid foot were significantly different (p<0.05). The values at the hallux, toe and Met1 in condition 5 also were significantly different (p<0.05). Conclusion: These findings showed that the symmetrical relative impulse of the foot was present in the case of carrying a backpack, but there was an extra load on specific regions and asymmetrical relative impulses in the case of carrying a shoulder bag, a across bag and a one-hand bag. (ED note: this abstract is not clear. You need to work on it.)

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