• The Journal of Korean Obstetrics and Gynecology
• /
• v.24 no.4
• /
• pp.150-162
• /
• 2011

Purpose: To investigate the change of the climacteric syndrome with women with induced menopause by hysterectomy or ovariectomy compared with women with natural menopause. Methods: Menopausal women(aged 45-55) were selected at two oriental medicine hospitals, Sam-se Oriental Medicine Hospital and Daegu Hannny Oriental Medicine Hospital. They were asked about Kupperman's Index, MENQOL and a few additional questions. They were divided into two groups: women with induced menopause by hysterectomy or ovariectomy and women with natural menopause. To analyse the Kupperman's index and MENQOL, SPSS for Windows 12.0 and Wilcoxon Ranked Sum Test were used. Results: The total sums of Kupperman's index and MENQOL were significantly correlated with women with induced menopause and women with natural menopause and women with induced menopause had higher total sums. Both the renal and urinary tract disorder and the sexual disorder were significantly correlated with women with induced menopause and women with natural menopause. The gastrointestinal and psychosocial disorder of Kupperman's index and MENQOL were not significantly correlated with women with induced menopause and women with natural menopause. Conclusions: Women with induced menopause by hysterectomy or ovariectomy experienced climacteric syndrome more severely compared with women with natural menopause, specifically the renal and urinary tract disorder and sexual disorder.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.33 no.1
• /
• pp.150-159
• /
• 2020

Objectives: This case report describes the management of three patients with menopausal disorder treated with Jaeumganghwa-tang, an herbal extract in national health insurance. Methods: Three patients suffering from Menopause disorder were hospitalized and treated with herbal extract Jaeumganghwa-tang for 4 weeks. This study was measured by Kupperman's Index, Menopause Rating Scale and EuroQol-Five Dimensions. Results: The symptoms of menopausal disorder have improved after treating with Jaeumganghwa-tang. Also the Kupperman's Index and Menopause Rating Scale have decreased, while the EuroQol-Five Dimensions has increased. Conclusions: As seen in these three cases, Jaeumganghwa-tang in herbal extract form has effects on the management of menopause disorder.

• Herbal Formula Science
• /
• v.20 no.2
• /
• pp.199-211
• /
• 2012

Objectives : The purpose of this study is to evaluate the effects of Gamisoyo-san on severe menopausal disorder patients. Methods : We recruited 2 severe menopausal disorder patients who have been suffering from hot flush and heat sensation. The patients had been administrated Gamisoyo-san. The patients of severe menopausal disorder had been estimated with Kupperman's index(KI), Menopause rating scale(MRS), Beck's depression Inventory(BDI), Visual analogue scale(VAS) and Heart rate variability (HRV). Kupperman's index, Menopause rating scale and Beck's depression inventory for every seven days. We measured VAS everyday. Heart rate variability was estimated twice, before and after treatment. Results : After the treatments, symptoms of menopausal disorder were decreased. Conclusions : This study suggests that Gamisoyo-san is significantly effective on severe menopausal disorder patients with hot flush and heat sensation.

• Journal of Oriental Neuropsychiatry
• /
• v.23 no.4
• /
• pp.199-214
• /
• 2012

Objectives : The purpose of this study is to evaluate the effects of Daeyeongjeongami-bang on menopausal disorder patients. Methods : We recruited 3 menopausal disorder patients who have been suffering from hot flush, fatigue and depression. In addition, the patients had been administrated Daeyeongjeongami-bang. The patients of menopausal disorder had been estimated with Kupperman's index, Menopause rating scale, Beck's depression Inventory, Self rating depression scale, Visual analogue scale and Heart rate variability. We measured Kupperman's index, Menopause rating scale, Beck's depression inventory and Self rating depression scale for every seven days. Heart rate variability was estimated twice, before and after the treatment. Results : After the treatments, symptoms of menopausal disorder were decreased. Conclusions : This study suggests that Daeyeongjeongami-bang is significantly effective on menopausal disorder patients with hot flush, fatigue and depression.

• Sleep Medicine and Psychophysiology
• /
• v.17 no.1
• /
• pp.11-15
• /
• 2010

Obstructive sleep apnea is a common sleep disorder that predominantly affects adult men than women. However, the prevalence in women increases with menopause dramatically. Menopause has long been described as a risk factor for obstructive sleep apnea. Recent large well-designed population studies support that menopause increases the risk for sleep-disordered breathing. The mechanism of that hypothesis is not yet clear. But, the decline in progesterone has been thought to influence the development of obstructive sleep apnea because progesterone is a respiratory stimulant and plays a protective role against sleep apnea. Increased visceral obesity and hypertension as major symptoms of metabolic syndrome are also associated with menopause and place women at increased risk for obstructive sleep apnea and other serious health problem. Hormone replacement therapy has been associated with a lower prevalence of sleep apnea. But, relative risk and benefits of hormone replacement therapy compared with other treatment options will require thorough consideration for each individual woman. Finally, attention should be drawn to the need for obstructive sleep apnea evaluation in perimenopausal and postmenopausal women.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.31 no.1
• /
• pp.138-146
• /
• 2018

Objectives: The purpose of this study is to evaluate the effects of Gamiguibi-hwan on Climacteric Syndrome. Method: We treated 50 cases menopausal disorder patients with Gamiguibi-hwan for 12 weeks. We estimated the effects by Menopause Rating Scale (MRS), Pittsburgh Sleep Quality Index (PSQI) and Beck's Depression Inventory II (BDI-II). Results: After treatment, the mean of MRS, PSQI and BDI-II score were decreased. Conclusions: This case shows that Gamiguibi-hwan is effective in treating menopausal disorder patients.

• The Journal of Internal Korean Medicine
• /
• v.38 no.5
• /
• pp.576-582
• /
• 2017

Objectives: Hormone replacement therapy may relieve many symptoms of menopause; however, hormone replacement therapy may increase the risk of breast cancer, stroke, and dementia. This case study describes the effect of Hoechunboeum-tang on the menopausal disorder of hot flashes, which has been well documented as a cause of distress to patients undergoing menopause. Methods and Results: Two female patients suffering from severe hot flashes related to menopausal disorders were administered the herbal medicine, Hoechunboeum-tang. Measurements included hot flash frequency over a 24 hour period, hot flash severity (visual analogue scale), and hot flash-related daily interference and were recorded during the last week before herbal medicine and again after 7 and 15 days of herbal treatment. The patients were asked about their hot flash symptoms 6 months later and both reported that the symptoms had been successfully reduced after herbal treatment and were still reduced after 6 months. Conclusions: Hoechunboeum-tang could have a beneficial effect on menopausal disorder with hot flashes.

• Sleep Medicine and Psychophysiology
• /
• v.9 no.2
• /
• pp.96-99
• /
• 2002

Menopause, the cessation of menstruation caused by the decline in estrogen production, occurs in 95% of women between 40 and 60 years. Sleep disturbance is a frequent complaint during the perimenopause period. In contrast to premenopausla women, menopausal women experience more reduction in the total sleep hours and report more sleep disturbances, such as insomnia, noctiria and sleep disordered breathing. But the prevalence, etiology and treatment of sleep disturbances in menopause are still controversal. So further investigations are required to elucidate the factors that account for the differences in sleep disturbance between premenopausal and postmenopausal women. There are suggestive data that estrogen and progesterone deficiency may increase the susceptibility for sleep disorder in menopause. Furthermore, there are suggestive evidence from observational studies and a limited number of randomized, controlled trials that hormone replacement therapy after menopause improves sleep. However, the clinical relevance of hormone replacement therapy is unproved. So the overall benefit of hormonal replacement in postmenopausal women with sleep related disorders should be individualized to avoid potential side effects. Several studies evaluated the role of melatonin, because this hormone has effects on core body temperature & insomnia. But the exact dosage and the effects of long-term use of melatonin are unclear. So, caution is indicated in melatonin administration.

• Journal of Oriental Neuropsychiatry
• /
• v.23 no.2
• /
• pp.67-84
• /
• 2012

Objectives : The purpose of this study is to evaluate the effects of Yeongkyekamjo-tang on patients with menopausal disorder. Methods : We recruited 3 patients with menopausal disorder, who have been suffering from palpitation and depression. In addition, the patients had been administrated Yeongkyekamjo-tang. The patients of menopausal disorder had been estimated with Kupperman's index, Beck's Depression Inventory, The Menopause Quiz of Argosy University, visual analogue scale and Heart rate variability. We measured the Kupperman's index, Beck's Depression Inventory and The Menopause Quiz of Argosy University for every seven days. The heart rate variability was estimated twice, before and after the treatment. Results : After the treatments, symptoms of menopausal disorder were decreased. Conclusions : This study suggests that Yeongkyekamjo-tang is significantly effective on patients with menopausal disorder as well as palpitation and depression.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.34 no.4
• /
• pp.78-96
• /
• 2021

Objectives: It is a statistical study to examine the data of CaPSPI (Diagnostic System for Climacteric and Postmenopausal Syndrome Pattern Identification), developed for diagnosis of menopause disorders and to record the status of treatment of it. Methods: From November 1, 2020 to June 19, 2021, 36 cases of data of 33 respondents of the CaPSPI were analyzed. For the use of the basic data of the clinical menopausal disorder, we investigated frequency of menopausal symptoms and the difference between them depending on the period of menopause, and the presentation of usage prescriptions. And the diagnostic results for three kinds' diagnosis [for examination (D1), for treatment (D2), by doctors (D3)] were compared. The diagnostic consistency of D1 and D3 and the statistical significance between DT and disease elements (證素) was investigated. Results: 1. Hot flush was the highest in the symptom survey of the menopause that the subjects complained of, followed by insomnia. There was no significant difference in symptom expression according to menopausal period. 2. The diagnostic consistency of D1 and D2 showed significant diagnostic consistency only in liver depression, and the diagnostic consistency of D1 and D3 showed significant consistency in liver depression and Dual Deficiency of Heart and Spleen. 3. D3' diagnosis and disease elements had statistical significance for cases of P<0.1 was found to be related to the theory of oriental medicine. Conclusions: It is needed to continue to accumulate diagnosis and treatment results through CaPSPI in the future to strengthen the basis for patten identification and treatment of menopause disorders.