• Archives of Pharmacal Research
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• v.26 no.10
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• pp.821-825
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• 2003

The effects of purple sweet potato anthocyanin (SPA) and Cordyceps mushroom extract (CME) on lipid peroxidation, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and cognitive deficits were examined. Both SPA and CME exhibited DPPH radical scavenging activities with similar potency. In contrast, only SPA was shown to effectively inhibit lipid peroxidation initiated by $Fe^{2+}$ and ascorbic acid in rat brain homogenates. Furthermore, SPA markedly enhanced cognitive performance, assessed by passive avoidance test in ethanol-treated mice. Combined treatments with SPA and CME did not significantly influence the effects of SPA alone. These results demonstrate that anthocyanin prepared from purple sweet potato exhibits memory enhancing effects, which may be associated with its antioxidant properties.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.2
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• pp.457-464
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• 2010

The haze removal algorithm using dark channel prior, which was proposed by He et al., is an efficient algorithm and presents impressive results. But its high memory and computational requirements limit its applications. In this paper, we propose a method to improve the memory usage and calculation speed. We notice that the matting process accounts for most calculation time, so we replace the matting process with a fast bilateral filtering scheme. Using the bilateral filter, we can reduce the memory usage, but its computational complexity is still high. To reduce the computational complexity as well, we adapt a hierarchical structure for the bilateral filtering. Experimental results show that the proposed algorithm can remove haze in a picture effectively, while requiring much less computations than the He et al.'s method.

• Journal of the Korean Institute of Intelligent Systems
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• v.15 no.5
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• pp.632-638
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• 2005

This paper describes a new data-handing, based on a Spatial Human Interface as human indicator, to the Spatial-Knowledge-Tags (SKT) in the spatial memory the Spatial Human Interface (SHI) is a new system that enables us to facilitate human activity in a working environment. The SHI stores human activity data as knowledge and activity history of human into the Spatial Memory in a working environment as three-dimensional space where one acts, and loads them with the Spatial-Knowledge-Tags(SKT) by supporting the enhancement of human activity. To realize this, the purpose of SHI is to construct new relationship among human and distributed networks computers and sensors that is based on intuitive and simultaneous interactions. In this paper, the specified functions of SKT and the realization method of SKT are explained. The utility of SKT is demonstrated in designing a robot motion control.

• Molecules and Cells
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• v.44 no.2
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• pp.68-78
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• 2021

Secondary metabolites enable plants to protect themselves from herbivorous insects. Among these, cucurbitacin B (cuc-B) is a bitter-tasting compound with promising pharmacological potential. Dietary exposure to cuc-B lowered the hemolymph glucose levels of Drosophila melanogaster fed with a high carbohydrate diet, which is homologous to high blood glucose in humans, and its effect was comparable to that of metformin, a well-known glucose-lowering drug. Furthermore, cuc-B reduced tissue sugar levels and glycogen levels, as well as triacylglycerol levels. Our results thus highlight the potential applicability of this compound to treat chronic metabolic diseases such as diabetes and obesity. Additionally, we analyzed sleep quality and taste-associative memory enhancement after cuc-B and metformin treatment. Both supplements increased nighttime bout length and metformin increased memory consolidation. Therefore, discarded shell of Cucurbitaceae could be processed into health supplements.

• The Korean Journal of Rehabilitation Nursing
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• v.3 no.2
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• pp.181-195
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• 2000

The purpose of this study is to find out the effects of personal characteristics, social support, depression, and metamemory on the older adults' memory performances. The subjects of the study consisted of 95 older adults over the age of 60 who are living in Busan. Some data were collected by means of the interview method, using questionnaires for metamemory (MIA questionnaire by Dixon, et al., 1988), and depression(GDS by Yesavage and Sheikl, 1986), social resoueces(Duke university, 1978), family support(Hyun-Sook Kang, 1985). The other data were collected by the testing method on the memory performance such as the immeadiate word recall task, the delayed word recall task, the word recognition task(Elderly Verbal Learning Test by Kyung Mi Choi, 1998), and the face recognition task(Face Recognition Task tool developed by Hye-Sook Min). The results of this study were as follows; 1. The level of metamemory is 3.4 points in the 5 point scale, the grades of the task and the achievement are relatively high and the grades of the change, the control, and the anxiety are relatively low in the sub-concepts. 2. Metamemory have significant relation with age(r=-.44), educational attainment(r=.46), depression(r=-.58), family support(r=.20), social resources(r=.20). 3. The significant variables to predict older adults' metamemory are educational attainment(22%), sex(11%), age (8.3%), depression(4.7%), and illness state(3%). 4. The strong variables to predict memory performances are metamemory, age, depression, social resources, educational attainment, illness state, and limitation of daily living activity related to illness. In conclusion, the enhancement strategies of metamemory and the social support and the prevention or reduction of depression are necessary to increase older adults' memory performances. Ultimately in this respect nurses' roles are very important in developing and performing some intervention programs for old adults' memory improvement, which have significant meanings in the field of nursing science.

• The KIPS Transactions:PartA
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• v.18A no.2
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• pp.61-68
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• 2011

Memory error debugging is one of the most critical processes in improving software quality. However, due to the extensive time consumed to debug, the enhancement often leads to a huge bottle neck in the development process of mobile devices. Most of the existing memory error detection tools are based on static error detection; however, the tools cannot be used in mobile devices due to their use of large working memory. Therefore, it is challenging for mobile device vendors to deliver high quality mobile devices to the market in time. In this paper, we introduce "PinMemcheck", a pin-based memory error detection tool, which detects all potential memory errors within $1.5{\times}$ execution time overhead compared with that of a baseline configuration by applying the Pin's binary instrumentation process and a simple data structure.

• Journal of Korean Academy of Nursing
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• v.49 no.3
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• pp.317-328
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• 2019

Purpose: The purpose of this study was to identify the effect of ghrelin on memory impairment in a rat model of vascular dementia induced by chronic cerebral hypoperfusion. Methods: Randomized controlled groups and the posttest design were used. We established the representative animal model of vascular dementia caused by bilateral common carotid artery occlusion and administered $80{\mu}g/kg$ ghrelin intraperitoneally for 4 weeks. First, behavioral studies were performed to evaluate spatial memory. Second, we used molecular biology techniques to determine whether ghrelin ameliorates the damage to the structure and function of the white matter and hippocampus, which are crucial to learning and memory. Results: Ghrelin improved the spatial memory impairment in the Y-maze and Morris water maze test. In the white matter, demyelination and atrophy of the corpus callosum were significantly decreased in the ghrelin-treated group. In the hippocampus, ghrelin increased the length of hippocampal microvessels and reduced the microvessels pathology. Further, we confirmed angiogenesis enhancement through the fact that ghrelin treatment increased vascular endothelial growth factor (VEGF)-related protein levels, which are the most powerful mediators of angiogenesis in the hippocampus. Conclusion: We found that ghrelin affected the damaged myelin sheaths and microvessels by increasing angiogenesis, which then led to neuroprotection and improved memory function. We suggest that further studies continue to accumulate evidence of the effect of ghrelin. Further, we believe that the development of therapeutic interventions that increase ghrelin may contribute to memory improvement in patients with vascular dementia.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.109-110
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• 2007

Plasma etching process에서 magnetic field 영향에 관한 연구이다. High level dry etch process를 위해서는 high density plasma(HDP)가 요구된다. HDP를 위해서 MERIE(Magnetical enhancement reactive ion etcher) type의 설비가 사용되며 process chamber side에 4개의 magnetic coil을 사용한다. 이런 magnetic factor가 특히 wafer edge부문에 plasma charging에 의한 damage를 유발시키고 이로 인해 device Vth(Threshold voltage)가 shift 되면서 제품의 program 동작 문제의 원인이 되는 것을 발견하였다. 이번 연구에서 magnetic field와 관련된 plasma charge damage를 확인하고 damage free한 공정조건을 확보하게 되었다.

• Journal of Life Science
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• v.19 no.6
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• pp.756-764
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• 2009

Scutellariae baicalensis GEORGt Acorus gramineus SOLAND and Gastrodia elata BLUME are traditional medicines used in the treatment of incipient stoke. In this study we investigated their effects on various aspects of neuronal differentiation in single or composite forms. Water-extracts of these medicines showed neuroprotective effects on cultured rat cortical neurons in normoxia and hypoxia. To understand the mechanism for neuroprotection we carried out various cell biological assays. They stimulated initial differentiation of neuronal development (transition from stage 1 to 2), and increased the number of spines and the length and number of dendritic processes. These effects were best manifested in the experimental group, which were given a mixture of the three kinds of extracts (p<0.01). To assess improvement of brain functions we carried out Morris water-maze tests for the mice that were fed on these extracts instead of water for 4 weeks. The experimental groups, especially those which were given the mixture of the three kinds of extract, showed significant (p<0.01) enhancement in memory as early as one day after the learning trial. These results indicate that these three kinds of extracts have synergistic effects on neuronal protection and improvement of brain functions.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2014.06a
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• pp.163-165
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• 2014

In this paper, we propose a world's first programmable video processing platform for video quality enhancement of 8K ($7680{\times}4320$) UHD (Ultra High Definition) TV at 60 frames per second. To support huge computation and memory bandwidth of video quality enhancement for 8K resolution, the proposed platform has unique features like symmetric multi-cluster architecture for data partitioning, ring data-path between clusters to support data pipelining, on-the-fly processing architecture to reduce DDR bandwidth, flexible hardware to accelerating common kernel in video enhancement algorithms. In addition to those features, general programmability of SRP (Samsung reconfigurable processor) as main core of the proposed platform makes it possible to upgrade continuously video enhancement algorithm even after the platform is fixed. This ability is very important because algorithms for 8K DTV is under development. The proposed sub-system has been embedded into SoC (System on Chip) and new 8K UHD TV using the programmable SoC is expected at CES2015 for the first time in the world.