• Journal of Microbiology and Biotechnology
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• v.28 no.2
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• pp.255-261
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• 2018

Aglycon protopanaxatriol (APPT) has valuable pharmacological effects such as memory enhancement and tumor inhibition. ${\beta}$-Glycosidase from the hyperthermophilic bacterium Dictyoglomus turgidum (DT-bgl) hydrolyzes the glucose residues linked to APPT, but not other glycoside residues. ${\beta}$-Glycosidase from the hyperthermophilic bacterium Pyrococcus furiosus (PF-bgl) hydrolyzes the outer sugar at C-6 but not the inner glucose at C-6 or the glucose at C-20. Thus, the combined use of DT-bgl and PF-bgl is expected to increase the biotransformation of PPT-type ginsenosides to APPT. We optimized the ratio of PF-bgl to DT-bgl, the concentrations of substrate and enzyme, and the reaction time to increase the biotransformation of ginsenoside Re and PPT-type ginsenosides in Panax ginseng leaf extract to APPT. DT-bgl combined with PF-bgl converted 1.0 mg/ml PPT-type ginsenosides in ginseng leaf extract to 0.58 mg/ml APPT without other ginsenosides, with a molar conversion of 100%. We achieved the complete biotransformation of ginsenoside Re and PPT-type ginsenosides in ginseng leaf extract to APPT by the combined use of two ${\beta}$-glycosidases, suggesting that discarded ginseng leaves can be used as a source of the valuable ginsenoside APPT. To the best of our knowledge, this is the first quantitative production of APPT using ginsenoside Re, and we report the highest concentration and productivity of APPT from ginseng extract to date.

• The Journal of the Acoustical Society of Korea
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• v.20 no.4
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• pp.22-28
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• 2001

This paper describes the implementation of a robust speaker position location system using the voice signal received by microphone array. To be robust to the reverberation which is the major factor of the performance degradation, low-frequency phase restoration algorithm which eliminates the influence of reverberations using the low-frequency information of the CPSP function is proposed. The implemented real-time system consists of a general purpose DSP (TMS320C31 of Texas instruments), analog part which contains amplifiers and filters, and digital part which is composed of the external memory and 12-bit A/D converter. In the real conference room environment, the implemented system that was constructed by the proposed algorithms showed better performance than the conventional system. The error of the TDOA estimation reduced more than 15 samples.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.1
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• pp.28-35
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• 2007

In this paper, an ultra low voltage SRAM design method based on dual-boosted cell bias technique is described. For each read/write cycle, the wordline and cell power node of the selected SRAM cells are boosted into two different voltage levels. This enhances SNM(Static Noise Margin) to a sufficient amount without an increase of the cell size, even at sub 1-V supply voltage. It also improves the SRAM circuit speed owing to increase of the cell read-out current. The proposed design technique has been demonstrated through 0.8-V, 32K-byte SRAM macro design in a $0.18-{\mu}m$ CMOS technology. Compared to the conventional cell bias technique, the simulation confirms an 135 % enhancement of the cell SNM and a 31 % faster speed at 0.8-V supply voltage. This prototype chip shows an access time of 23 ns and a power dissipation of $125\;{\mu}W/Hz$.

• Proceedings of the Korea Information Assurance Society Conference
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• 2004.05a
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• pp.103-108
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• 2004

A Home Location Register(HLR) database system manages each subscriber's location information, which continuously changes in a cellular network. For this purpose, the HLR database system provides table management, index management, and backup management facilities. In this thesis, I propose using a two-level index method for the mobile directory number(MDN) as a suitable method and a chained bucket hashing method for the electronic serial number(ESN). Both the MDN and the ESN are used as keys in the HLR database system. I also propose an efficient backup method that takes into account the characteristics of HLR database transactions. The retrieval speed and the memory usage of the two-level index method are better than those of the T-tree index method. The insertion and deletion overhead of the chained bucket hashing method is less than that of the modified linear hashing method. In the proposed backup method, I use two kinds of dirty flags in order to solvethe performance degradation problem caused by frequent registration-location operations. I also propose using additional attributes in the HLR database scheme for location information secrecy as a suitable security method.

• Information and Communications Magazine
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• v.24 no.4
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• pp.27-35
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• 2007

음성 통신을 할 때 배경 잡음이 존재하게 되면 일반적으로 음질이 저하된다. 이것은 잡음 자체가 듣기 싫다거나 음성을 더 작게 들리게 만들기 때문이기도 하고 음성 코덱이 잡음이 섞이지 않은 깨끗한 음성에 최적화되어 있어서 잡음이 섞인 음성에 대한 코딩 효율이 떨어지기 때문이기도 하다. 이 논문에서는 잡음에 의한 음성 통신의 품질 저하를 막기 위한 방법으로서 음성 향상(speech enhancement) 기술과 음성 강화(speech reinforcement) 기술에 대해 소개한다. 음성 향상 기술이란 전송부의 마이크에서 녹음된 잡음과 음성이 섞인 입력 음성으로부터 깨끗한 음성을 추정하는 기술을 말한다. 음성 향상 기술은 상당히 오랜 기간 동안 연구되어 온 기술이며, 최근에는 각 파라미터의 분포에 의존하는 방법보다 확률 모델에 기반한 방법이 각광을 받고 있으며 인간의 청각 특성을 고려한 음성 향상 방법도 제안되고 있다. 음성 강화 기술이란 수신단에서 주변 잡음에 따라 전송되어 온 음성을 주파수별로 증폭하여 더 잘 들리도록 만드는 기술이다. 음성 향상이 내 주위의 잡음이 상대방에게 들리는 음성에 미치는 영향 혹은 상대방 주변의 잡음이 나에게 들리는 소리에 미치는 영향을 줄여주는 기술이라면 음성 강화는 내 주위의 잡음이 나에게 들리는 음성에 미치는 영향을 상쇄해 주는 기술이다. 이 경우 주변 잡음은 어떤 전자 시스템도 거치지 않고 귀로 직접 들어오기 때문에 잡음 자체를 줄여 주는 것은 힘들고 전송되어 온 음성을 적절히 증폭 혹은 변형함으로써 귀에 들리는 음질 또는 명료성을 개선하게 된다. 이 논문에서는 통계 모델을 기반으로 한 음성 향상 기법과 인간의 청각 특성을 고려한 음성 향상 기법, 그리고 음성 강화 기법에 대해 설명한다.을 시도한 결과 안정적이고 반복 가능한 급성 심부전 모델을 얻을 수 있었다. bench scale실험결과와 같이 AOC는 배수관망에서의 박테리아 증식과 크게 상관관계를 갖고 있는 것으로 밝혀졌다.)', 'have a headache (2.10±0.79)', 'poor memory (2.09±0.83)', 'no appetite (1.99±0.85)', As for the correlation between iron parameter and clinical symptoms related to anemia, the hematocrit rate was negatively correlated with 'get a cold easily', 'pale face', 'feeling blue', 'difficult digestion' (p<0.05). The level of iron was negatively correlated with 'tired out easily', 'get a cold easily' (p<0.05) and TS (%) were negatively correlated with 'tired out easily (p<0.05)', 'get a cold easily (p<0.01). Our study resulted that the prevalence of a iron deficiency of a middle school girl is very high, therefore the guidelines for iron supplementation and nutritional education to improve their iron status should be provided.한 질소제거를 N-balance로부터

• The Journal of Korean Institute of Communications and Information Sciences
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• v.42 no.2
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• pp.316-322
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• 2017

This paper suggests an efficient software implementation of lightweight encryption algorithm PRESENT which supports for secret key lengths of 80-bits. Each round of PRESENT is composed of the round key addition, substitution, and permutation and is repeated 31 times. Bo Zhu suggested combined substitution and permutation for efficient operation so that encryption throughput has been increased 2.6 times than processing substitution and permutation at separate times. The scheme that suggested in this paper improved the scheme of Bo Zhu to reduce the number of operation for the round key addition, substitution, and permutation. The scheme that suggested in this paper has increased encryption throughput up to 1.6 times than the scheme of Bo Zhu but memory usage has been increased.

• Journal of IKEEE
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• v.10 no.2 s.19
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• pp.156-160
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• 2006

Capacitance versus voltage (C-V) curves of Ge-nanocrystal (NC)-embedded MOS capacitors with and without a single capping Al2O3 layer are characterized in this work. C-V curves of the Ge-NC-embedded MOS capacitor with the A12O3 layer are counterclockwise in the voltage sweeps, which indicates tile presence of charge storages in the Ge NCs by the tunnelling of charge carriers between the Si substrate and the Ge NCs. In the Ge-NC-embedded MOS capacitor without Al2O3 layer, clockwise hysteresis of the C-V curves and leftward shifts of the flat band voltages are observed for the embedded MOS capacitor without the Al2O3 layer. It is suggested that the characteristics of the C-V curves are due to the charge trapping at oxygen vacancies within a SiO2 layer. In addition, the illumination of the white light enhances the lower capacitance part of the C-V hysteresis. The origin for the enhancement is discussed in this paper.

• Journal of Practical Engineering Education
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• v.12 no.1
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• pp.41-47
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• 2020

This study aims to investigate effects of brain-based learning. 27 primary studies were selected through rigorous search process and analyzed through meta-analytic methods. Research findings are as follows. First, the total effect size was .67. Second, the effect of dependent variables was academic achievement, cognitive domain, and affective domain in order. Third, with respect to types of cognitive domain, the effect was self-regulation, creativity, competence, communication, and research ability in order. Fourth, the effect of affective domains was sociality, learning interest, and subject attitude in order. Fifth, regarding development of cognitive ability, the effect size was combined, brain training, learning environments, and right brain activities in order. Sixth, the effect of learning activities was memory improvement and attention enhancement in order.

• Korean Chemical Engineering Research
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• v.47 no.1
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• pp.1-10
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• 2009

As a demand for the portable device requiring smaller size and better performance is in hike, reducing the size of conventionally used planar 2 dimensional chip cannot be a solution for the enhancement of the semiconductor chip technology due to an increase in RC delay among interconnects. To address this problem, a new technology - "3 dimensional (3D) IC chip stack" - has been emerging. For the integration of the technology, several new key unit processes (e.g., silicon through via, wafer thinning and wafer alignment and bonding) should be developed and much effort is being made to achieve the goal. As a result of such efforts, 4 and 8 chip-stacked DRAM and NAND structures and a system stacking CPU and memory chips vertically were successfully developed. In this article, basic theory, configurations and key unit processes for the 3D IC chip integration, and a current tendency of the technology are explained. Future opportunities and directions are also discussed.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.10B
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• pp.630-638
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• 2005

As real-time media applications based on IP multicast networks spread widely, the end-to-end QoS (quality of service) provisioning for these applications have become very important. To guarantee the end-to-end QoS of multi-party media applications, it is essential to monitor the time-varying status of both network metrics (i.e., delay, jitter and loss) and system metrics (i.e., CPU and memory utilization). In this paper, targeting the multicast-enabled AG (Access Grid) group collaboration tool based on multi-Party real-time media services, a hybrid monitoring scheme that can monitor the status of both multicast network and node system is investigated. It combines active monitoring and passive monitoring approaches to measure multicast network. The active monitoring measures network-layer metrics (i.e., network condition) with probe packets while the passive monitoring checks application-layer metrics (i.e., user traffic condition by analyzing RTCP packets). In addition, it measures node system metrics from system API. By comparing these hybrid results, we attempt to pinpoint the causes of performance degradation and explore corresponding reactions to improve the end-to-end performance. The experimental results show that the proposed hybrid monitoring can provide useful information to coordinate the performance improvement of multi-party real-time media applications.