• 제목/요약/키워드: Membrane interaction

검색결과 471건 처리시간 0.023초

디퓨져와 노즐을 이용한 열공압형 마이크로 펌프의 열공압 및 유동특성에 관한 수치해석적 연구 (A Numerical Study on the Thermopneumatic and Flow Characteristics of Diffuser-Nozzle Based Thermopneumatic Micropumps)

  • 정진;김창녕
    • 설비공학논문집
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    • 제17권7호
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    • pp.642-648
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    • 2005
  • This study has been conducted to investigate the thermopneumatic and flow characteristics of diffuser/nozzle based thermopneumatic micropumps. In this study, a transient three-dimensional numerical analysis using FSI (Fluid-Structure Interaction) model has been employed to analyze the effects of the interaction between the membrane and two fluids (air and water) in the thermopneumtic micropump. The transient temperature and pressure in the cavity, the transient displacements of the membrane and the net flow rate of the micropump have been closely calculated for the frequency of 1 Hz. It has been found that the difference of the flow rates at the inlet and outlet is larger in the cooling period than in the heating period and that the duty ratio is very important in association with pump performance because the temperature in the cavity ascends drastically in the heating period and descends slowly in the cooling period. This study can be regarded as fundamental understandings for the design and analysis of thermopneumatic micropumps.

Evidence for Regulation of Interaction of Endogenous Protein Kinase C(Pkc) Substrates with Plasma Membrane by PKC Down-Regulation in K562 Cells

  • Kim, Young-Sook
    • Archives of Pharmacal Research
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    • 제18권5호
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    • pp.301-307
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    • 1995
  • In the particulate fraction obtained from PKC-down regulated K562 cells by treatment for 24 h with 200nM TPA, phosphorylation of two proteins with molecular weight, 100 kDa and 23 kDa (designated p100 and p23, respectvely) was depleted and addition of exogenous purified PKC to this fraction failed to testore their phosphorylation. However, in the soluble fraction, all of phosphoproteins abolished by long-term treatment with TPA were restored by exogenously added PKC. Phosphorylation of two proteins was increased by short-term tretment (20 min), and diminished with the persistant exposure to TPA as well as at a concentration as low as 1nM. When K562 cells were treated with 1 nM and 200 nM TPA for 24 h, phosphorylation of p100 was restored with or without exogenous PKC on 2-3day and 6day after removal of treated TPA, respectively. Two-dimensional electrophoresis of phosphoproteins revealed that phosphorylated p100 (pl=5.9) and p66 species were completely absent from the particulate fraction of K562 cells treated with 200nM TPA for 24 h. These results suggest that the interaction of sensitive endogenous substrates, p100 and p23 with the plasma membrane might be regulated by PKC-down regulation without displacement to the cytosol and the interaction of p100 with the membrane might be reveersible.

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Wave-blocking Efficiency of a Horizontal Porous Flexible Membrane

  • Cho, Il-Hyoung
    • International Journal of Ocean Engineering and Technology Speciallssue:Selected Papers
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    • 제6권1호
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    • pp.7-14
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    • 2003
  • The interaction of monochromatic incident waves with a submerged horizontal porous membrane is investigated in the context of two-dimensional linear hydro-elastic theory. It is assumed that the membrane is made of material with very fine pores so that the normal velocity of the fluid passing through the porous membrane is linearly proportional to the pressure difference between two sides of the membrane (e.g. Darcy's law). Using the Eigen-function expansion method, the wave-blocking performance of a submerged horizontal porous membrane is tested with various membrane tensions, porosities, lengths, and submerged depths. It is found that an optimal combination of design parameters exists for given water depth and wave characteristics.

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Localization of Sop Proteins and Interaction of Plasmid DNA with the Cell Membrane of Host Bacteria in Partitioning

  • Kim, Sung-Uk;Nagai, Kazuo;Tamura, Gakuzo;Yu, Ju-Hyun
    • Journal of Microbiology and Biotechnology
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    • 제3권4호
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    • pp.261-265
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    • 1993
  • A sopA protein (41K) encoded by plasmid pXX288 was observed in the cytoplasm, whereas a sopB protein (37K) encoded by plasmid pXX157 was observed in the membrane fraction. Most of the sopB protein was solubilized from the crude membrane by treatment with Sarkosyl, which suggested that the protein may be located in the inner membrane. The sopA protein was precipitated at the concentration of 30 to 60% ammonium sulfate. The sedimentation profile of the crude membrane fraction showed a little difference according to culture media used, and the sopB protein existed in all fractions of inner membrane. The DNA of plasmids, pXX157, pXX300, and pXX167 co-sedimented with inner membrane fraction.

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Nanofiltration of Electrolytes with Charged Composite Membranes

  • Choi, J.H.;Yeom, C.K.;Lee, J.M.;Suh, D.S.
    • 멤브레인
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    • 제13권1호
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    • pp.29-36
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    • 2003
  • A characterization of the permeation and separation using single salt solution was carried out with charged composite membranes. Various charged composite membranes were fabricated by blending an ionic polymer with a nonionic polymer in different ratios. In this study, sodium alginate, chitosan and poly(vinyl alcohol) were employed as anionic, cationic and nonionic polymers, respectively. The permeation and separation behaviors of the aqueous salt solutions have been investigated through the charged composite membranes with various charge densities. As the content of the ionic polymer increased in the membrane, the hydrophilicity of the membrane increased, and pure water flux and the solution flux increased correspondingly, indicating that the permeation performance through the membrane is determined mainly by its hydrophilicity. Electrostatic interaction between the charged membrane and ionic solute molecules, that is, Donnan exclusion, was observed to be attributed to salt rejection to a greater extent, and molecular sieve mechanism was effective for the separation of salts under a similar electrostatic circumstance of solutes.

Characterization and pervaporation of chitosan/ polyacrylic acid polyelectrolyte complex membranes

  • Nam, Sang-Yong;Lee, Young-Moo
    • 한국막학회:학술대회논문집
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    • 한국막학회 1996년도 춘계 총회 및 학술발표회
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    • pp.60-61
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    • 1996
  • Polyanion-polycation complexes had been known for a long time on an empirical basis fromthe mutual precipitation of proteins, before Kossel at the end of the previous century recognized the electrostatic nature of the interaction between oppositely charged polyions. The formation of polyelectmlyte complexes is essentially a result of the electrostatic nature of the interaction between oppositely charged polyions. This interaction in the macroscopic homogeneous system the phase transition by polysalt precipitation as well as the chemical and physical structure of polyelectrolyte complex membranes have been intensively investigated from the themodynamical and kinetical point of view.

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Evolutionary Signature of Information Transfer Complexity in Cellular Membrane Proteomes

  • Kim, Jong-Min;Kim, Byung-Gee;Oh, S.-June
    • Genomics & Informatics
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    • 제7권2호
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    • pp.111-121
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    • 2009
  • Cell membrane proteins play crucial roles in the cell's molecular interaction with its environment and within itself. They consist of membrane-bound proteins and many types of transmembrane (TM) proteins such as receptors, transporters, channel proteins, and enzymes. Membrane proteomes of cellular organisms reveal some characteristics in their global topological distribution according to their evolutionary positions, and show their own information transfer complexity. Predicted transmembrane segments (TMSs) in membrane proteomes with HMMTOP showed near power-law distribution and frequency characteristics in 6-TMS and 7-TMS proteins in prokaryotes and eukaryotes, respectively. This reaffirms the important roles of membrane receptors in cellular communication and biological evolutionary history.

정밀여과에서 임계플럭스(Critical flux)에 관한 이론 및 실험적 고찰 (The Critical Flux in Microfiltration: Comparison between Theoretical and Experimental Values)

  • 윤성훈;이정학
    • 멤브레인
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    • 제7권3호
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    • pp.150-156
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    • 1997
  • 입자의 정밀여과에 있어 임계플럭스의 이론치를 계산하기 위해 확산(diffusion), 횡방향이동(lateral migration), 전단유도확산(shear induced diffusion), 그리고 입자의 정전기적 반발력에서 기인하는 상호작용에 의한 상승이동(interation enhanced migration) 등의 입자의 역전달 이동을 고려하였다. 보통의 여과조건에서 제타전위의 절대치가 20~40mV이고 직경이 0.1$\mu{m}$~10$\mu{m}$인 입자의 경우 상호작용에 의한 이동이 가장 중요한 역전달 메카니즘이었다. 입자크기에 따라 계산된 임계플럭스값을 실험적으로 확인하기 위해 다양한 크기를 갖는 구형인 적철광(hematite)입자를 합성하여 여과실험을 수행하였다. 이 실험치는 역전달 이론에 의해 예측된 플럭스의 이론치와 비교적 잘 일치하였다.

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SOLUTION CHARACTERISTICS AND MEMBRANE FORMATION OF PARTIALLY IMIDIZED POLY (AMIC ACID)

  • Lee, Hyuck-Jai;Won, Jong-Ok;Park, Hyun-Chae;Lee, Hoo-Sung;Kang, Yong-Soo
    • 한국막학회:학술대회논문집
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    • 한국막학회 1999년도 The 7th Summer Workshop of the Membrane Society of Korea
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    • pp.83-86
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    • 1999
  • The imidization effect of a poly (amic acid) dope solution on membrane formation has been investigated. Poly (amic acid) solution in S-methyl-2-pyrrolidione hs been thermally imidized at $120^{\circ}C$ with different curing time and its degree of imidization was determined by infrared spectroscopy. The solution properties have been studied as a function of concentration and curing time by dynamic light scattering. The quality of a solvent was changed from good to poor with increasing imidization of poly(amic acid).The reduced polymer-solvent interaction diminishes the membrane formation time. The morphology of a membrane was able to be controlled by the characteristics of dope solution.

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Pontoon and Membrane Breakwater

  • 기성태
    • 한국해양공학회:학술대회논문집
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    • 한국해양공학회 2003년도 춘계학술대회 논문집
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    • pp.185-191
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    • 2003
  • A numerical study on the hydrodynamic properties of a floating flexible breakwater consisting of triple vertical porous membrane structures attached to a floating rigid pontoon restrained by moorings is carried out in the context of two-dimensional linear wave-flexible body interaction theory. The tensions in the triple membranes are achieved by hanging a clump weight from its lower ends. The clump weight is also restrained properly by moorings. The dynamic behavior of the breakwater was described through an appropriate Green function, and the fluid multi-domains are incorporated into the boundary integral equation. Numerical results are presented which illustrate the effects of the various wave and structural parameters on the efficiency of the breakwater as a barrier to wave action. It is found that the wave reflection and transmission properties of the structures depends strongly on the membrane length taking major fraction of water column, the magnitude of tensions on membrane achieving by the clump weight, proper mooring types and stiffness, the permeability on the membrane dissipating wave energy.

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