• Korean Journal of Biological Psychiatry
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• v.5 no.2
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• pp.235-242
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• 1998

Objectives : Alcohol-induced oxidative stress has been known to injure various tissues or organs. This stress is related with free radicals which are produced as the result of long-term alcohol consumption. Malonyldialdehyde(MDA) is produced by the interaction of free radicals and cell membrane lipids, and indicates the degree of lipid peroxidation indirectly. The purpose of this study was to investigate the relationship between red blood cell(RBC) membrane lipid peroxidation by free radicals, and associated hepatic injuries and hematologic changes. Methods : Thirty-three subjects diagnosed as alcohol dependence according to DSM-IV diagnostic criteria were evaluated within 72 hours after discontinuing alcohol drinking. Clinical characteristics were evaluated by CAGE questionnaire and Korean Michigan Alcoholism Screening Test(MAST). RBC membrane MDA level was measured as the marker of RBC membrane lipid peroxidation. Aspartate aminotransferase(AST), alanine aminotransferase(ALT) and gamma-glutamyltransferase(GGT) were used as the biochemical markers of liver damage due to alcohol ingestion. The alcohol-induced hematologic change was assessed by mean corpuscular volume(MCV). Results : The results were as follows. Clinical characteristics were not different between two groups having normal and abnormal levels of AST, ALT, GGT or MCV. The levels of MDA were not correlated with the clinical characteristics and serum levels of AST, ALT and GGT. However, there was a significant correlation between the levels of MDA and the value of MCV(p=0.017). Conclusions : These findings suggest that oxidative stress in alcohol dependence may not be reflected in liver enzyme markers such as AST, ALT and GGT, but may be reflected in MCV.

• International Journal of Highway Engineering
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• v.4 no.3 s.13
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• pp.15-23
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• 2002

The waterproofing system's performance is known to show a determing by complex interaction of material factors, design details, and the quality of construction, and the waterproofing integrity of waterproofing membranes is determined by the bond to the deck and the amount of damage to the waterproofing membrane. In this research, the basic properties of waterproofing membranes on market and the tensile adhesive chracteristics of waterproofing systems of concrete bridge deck have also been investigated in the view of the damages frequently reported from job site. For the tensile adhesive strength of sheet waterproofing membranes, the results after asphalt concrete paving tends to increase more than before those. The results of the liquid waterproofing membranes are upside-down, and the more concrete has strength, the more strength of tensile adhesive increase. The ambient temperature of asphalt concrete when application of the waterproofing membrane has considerable influence on the performance of waterproofing system. As described above, waterproofing system can be influenced by several factors. If they are not considered under construction, the overlooking will cause the damages of pavement and waterproofing system after traffic opening.

• Journal of Korean Society of Water and Wastewater
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• v.25 no.4
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• pp.479-488
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• 2011

Nanofiltration was performed with polyaluminium chloride solutions at different pH conditions to understand effects of inorganic compounds on aluminum hydrolysis products, i.e., three distinctive groups of aluminum species: polymeric Al at low pH; $Al(OH)_3$ at neutral pH; and ${Al(OH)_4}^-$ at high pH. The PACl solution was prepared to be approximately 4.0mM and adjusted to the designated pH. The influence of inorganic compounds on Al species fouling was investigated with 4.9mM $CaCl_2$ and 3.5mM $MgSO_4$ because $Ca^{2+}$, $Mg^{2+}$, $Cl^-$, ${SO_4}^{2-}$ are the most common inorganics in the drinking water. NF membrane fouling was measured by flux decline rate. The impact of $CaCl_2$ was not significant on the individual Al hydrolysis products fouling. However, the flux decline rate was drastically changed in the presence of $MgSO_4$. The concentration of particulate matters was considerably increased possibly due to interaction between Al species and ${SO_4}^{2-}$ where $MgSO_4$ was introduced. The particulates were accumulated on the membrane and enhanced the hydraulic resistance of the cake layer. In addition, conductivity removal of the membrane was decreased when Al-hydroxide was dominant due to reduction of membrane surface charge. The rejection of $Ca^{2+}$and $Mg^{2+}$ were considerably different, which implys that composition of inorganics paly a role on conductivity removal.

• Analytical Science and Technology
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• v.28 no.1
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• pp.65-71
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• 2015

Intracellular organelles in eukaryotic cells play important roles in many cellular functions. Intracellular trafficking of many proteins to specific intracellular organelles is tightly regulated by various mechanisms in cells. Therefore, elucidating the targeting mechanism of novel markers for intracellular organelles is important for cellular physiology and pathology. In this study, we tried to identify the peptides which could bind to specific glycolipid in cellular membrane using GFP-fused glycolipid-binding peptides, and analyzed their cellular localization. As a result, we could identify mitochondria-, Golgi- or plasma membrane-targeting peptides. Furthermore, we found that the plasma membrane-targeting peptide was localized to the plasma membrane via electrostatic interactions. Thus, our results suggest that various glycolipid-binding peptides could be used as intracellular organelles markers.

• Bulletin of the Korean Chemical Society
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• v.12 no.5
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• pp.474-477
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• 1991

The preferential transport phenomena of neutral cation-anion moieties in neutral macrocycle-facilitated emulsion liquid membrane were described in this study. Emulsion membrane systems consisting of (1) aqueous source phase containing 0.001 M M($NO_3$)$_2(M=Mn^{2+},\;Co^{2+},\;Ni^{2+},\;Cu^{2+},\;Zn^{2+},\;Sr^{2+},\;Cd^{2+},\;and\;Pb^{2+})$ (2) a toluene membrane containing 0.01 M ligand $(DBN_3O_2$, DA18C6, DT18C6, TT18C6, HT18C6) and the surfactant span 80 (sorbitan monooleate) (3% v/v) and (3) an aqueous receiving phase containing $Na_2S_2O_3$ or $NaNO_3$ were studied with respect to the disappearence of transition metal ions from the source phase as a function of time. Cation transports for various two component or three component equimolar mixture of transition metal and $Cu^{2+}$ in a emulsion membrane system incorporating macrocyclic ligand (HT18C6) as carrier were determinded. $Cu^{2+}$ was transported higher rates than the other $M^{2+}$ in the mixture solution. Equilibrium constants for cation-source phase co-anion, cation macrocycle and cation-receiving phase reagent interaction are examined as parameters for the prediction of cation transport selectivities.

• Membrane Journal
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• v.34 no.3
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• pp.182-191
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• 2024

This review addresses the pressing need for effective wastewater treatment methodologies by exploring advanced thin-film nanocomposite (TFN) nanofiltration membranes aimed at efficient dye removal from industrial effluents. Utilizing insights from recent research, the review focuses on the fabrication of TFN membranes incorporating innovative materials such as nanocarbons, silica nanospheres, metal-organic frameworks (MOFs), and MoS₂. The primary goals are to enhance dye removal efficiency, improve antifouling properties, and maintain high selectivity for dye/salt separation. By leveraging the distinct advantages of these nanomaterials-including large surface areas, mechanical robustness, and specific pollutant interaction capabilities-this review aims to overcome the limitations of current nanofiltration technologies and provide sustainable solutions for water treatment challenges.

• Journal of Photoscience
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• v.9 no.2
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• pp.102-105
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• 2002

Phoborhodopsin (pR or sensory rhodopsin II, sRII; the absorption maximum of ∼ 500 nm) is a retinoid protein and works as a photoreceptor of the negative phototaxis of Halobacterium salinarum. pharaonis phoborhodopsin (ppR or pharaonis sensory rhodopsin II, psRII) is a corresponding protein of Natronobacterium pharaonis. These sensory proteins form a complex with a cognate transducer protein in the membrane, and this complex transmits the light-signal to the cytoplasm to evoke avoidance reaction from blue-green light. Recently, the functional expression in Escherichia coli membrane of ppR was achieved, which can afford a large amount of the protein and enables mutant studies to clarify the role of various amino acid residues. A truncated transducer which can bind to ppR is also expressed in Escherichia. coli membrane. In this article, we will review properties of ppR mainly using observations of our laboratory; which contains photochemistry (photocycle), light-driven proton uptake, release and transport, F -helix titling during photocycle and association of the transducer.

• Proceedings of the Korea Concrete Institute Conference
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• 2002.05a
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• pp.373-378
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• 2002

The waterproofing system's performance is known to show a determining by complex interaction of material factors, design details, and the qualify of construction, and the waterproofing integrity of waterproofing membranes is determined by the bond to the deck and the amount of damage to the waterproofing membrane. In this research, the basic properties of waterproofing membranes on market and the tensile adhesive characteristics of waterproofing systems of concrete bridge deck have also been investigated in the view of the damages frequently reported from job site. As a results of tensile adhesive strength of waterproofing system, tensile strength is decrease with surface moisture contents except for inorganic-elastomeric liquid waterproofing membrane, and increase with strength of deck slab. Also tensile adhesive strength is generally increase in case of moisture curing of specimen because of pore structure and surface leveling. The after asphalt concrete paving tends to increase more than before those. The results of the liquid waterproofing membranes are upside-down, and the more concrete has strength, the more strength of tensile adhesive increase. The ambient temperature and the rolling temperature of asphalt concrete when application of the waterproofing membrane has considerable influence on the performance of waterproofing system.

• Journal of Microbiology and Biotechnology
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• v.27 no.1
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• pp.43-48
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• 2017

In a previous study, we analyzed the transcriptome of Scolopendra subspinipes mutilans using next-generation sequencing technology and identified several antimicrobial peptide candidates. One of the peptides, scolopendrasin V, was selected based on the physicochemical properties of antimicrobial peptides using a bioinformatics strategy. In this study, we assessed the antimicrobial activities of scolopendrasin V using the radial diffusion assay and colony count assay. We also investigated the mode of action of scolopendrasin V using flow cytometry. We found that scolopendrasin V's mechanism of action involved binding to the surface of microorganisms via a specific interaction with lipopolysaccharides, lipoteichoic acid, and peptidoglycans, which are components of the bacterial membrane. These results provide a basis for developing peptide antibiotics.

• Journal of the Society of Naval Architects of Korea
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• v.48 no.5
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• pp.451-456
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• 2011

To ensure structural integrity of membrane type LNG tank, the rational assessment of the sloshing impact responses of tank structures should be preceded. The sloshing impact pressures acting on the insulation system of LNG tank are typical irregular loads and the resulting structural responses show very complex behaviors accompanied with fluid structure interaction. So it is not easy to estimate them accurately and immense time consuming calculation process would be necessary. In this research, a simplified method to analyse the dynamic structural responses of LNG tank insulation system under pressure time histories obtained by sloshing model test or numerical analysis was studied. The proposed technique based on the concept of linear combination of the triangular response functions which are the transient responses of structures under the unit triangular impact pressure acting on structures. The validity of suggested method was verified through the example calculations and applied to the dynamic structural response analysis of a real Mark III membrane type insulation system using the sloshing impact pressure time histories obtained by model test.