• The Journal of Korean Medicine
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• v.43 no.1
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• pp.73-86
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• 2022

Objectives: In the health care industry, the influence of online reviews is growing. As medical services are provided mainly by providers, those services have been managed by hospitals and clinics. However, direct promotions of medical services by providers are legally forbidden. Due to this reason, consumers, like patients and clients, search a lot of reviews on the Internet to get any information about hospitals, treatments, prices, etc. It can be determined that online reviews indicate the quality of hospitals, and that analysis should be done for sustainable hospital marketing. Method: Using a Python-based crawler, we collected reviews, written by real patients, who had experienced Korean medicine, about more than 14,000 reviews. To extract the most representative words, reviews were divided by positive and negative; after that reviews were pre-processed to get only nouns and adjectives to get TF(Term Frequency), DF(Document Frequency), and TF-IDF(Term Frequency - Inverse Document Frequency). Finally, to get some topics about reviews, aggregations of extracted words were analyzed by using LDA(Latent Dirichlet Allocation) methods. To avoid overlap, the number of topics is set by Davis visualization. Results and Conclusions: 6 and 3 topics extracted in each positive/negative review, analyzed by LDA Topic Model. The main factors, consisting of topics were 1) Response to patients and customers. 2) Customized treatment (consultation) and management. 3) Hospital/Clinic's environments.

• Genomics & Informatics
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• v.21 no.4
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• pp.46.1-46.10
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• 2023

Colon adenocarcinoma (COAD) is the predominant type of colorectal cancer. Early diagnosis and treatment can significantly improve the prognosis of COAD patients. Anoctamin 7 (ANO7), an anion channel protein, has been implicated in prostate cancer and other types of cancer. In this study, we analyzed the expression of ANO7 and its correlation with clinicopathological characteristics among COAD patients using the Gene Expression Profiling Interactive Analysis 2 (GEPIA2) and the University of Alabama at Birmingham CANcer (UALCAN) databases. The GEPIA2, Kaplan-Meier plotter, and the Survival Genie platform were employed for survival analysis. The co-expression network and potential function of ANO7 in COAD were analyzed using GeneFriends, the Database for Annotation, Visualization and Integrated Discovery (DAVID), GeneMANIA, and Pathway Studio. Our data analysis revealed a significant reduction in ANO7 expression levels within COAD tissues compared to normal tissues. Additionally, ANO7 expression was found to be associated with race and histological subtype. The COAD patients exhibiting low ANO7 expression had lower survival rates compared to those with high ANO7 expression. The genes correlated with ANO7 were significantly enriched in proteolysis and mucin type O-glycan biosynthesis pathway. Furthermore, ANO7 demonstrated a direct interaction and a positive co-expression correlation with mucin 2 (MUC2). In conclusion, our findings suggest that ANO7 might serve as a potential prognostic biomarker and potentially plays a role in proteolysis and mucin biosynthesis in the context of COAD.

• Journal of Biomedical Engineering Research
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• v.36 no.1
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• pp.7-15
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• 2015

The egg white phantom is a thermal lesion visualization phantom able to illustrate a thermal lesion. It is often used to evaluate the performance of HIFU and is less expensive than the BSA phantom. This study determined the optimal phantom composition for evaluated therapeutic ultrasound machines by varying the egg white concentration in the egg white phantom and demonstrated its utility as a therapeutic ultrasound phantom. The egg white phantom at varying egg white concentrations (10-40% in 10% intervals) was fabricated, and its thermal properties and acoustic properties were assessed. In addition, the size and shape of the formed lesion were compared between the egg white phantom and bovine liver tissue according to the electrical power. The results showed that 30% egg white phantom was optimal for the performance evaluation due to its thermal and acoustic properties. The generated thermal lesions formed sequentially as a cigar, ellipse, tadpole, and cone shapes according to the electrical power; a similar tendency was observed in the liver tissue. Hence, we conclude that the egg white phantom will prove useful in quantitatively evaluating the thermal effects of therapeutic ultrasound.

• International Journal of Knowledge Content Development & Technology
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• v.10 no.2
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• pp.51-69
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• 2020

This paper describes global research in the field of augmented reality (22078) as indexed in Scopus database during 1992-2019, using a series of bibliometric indicators. The augmented reality (AR) research registered high 54.23% growth, averaged citation impact of 8.90 citations per paper. Nearly 1% of global output in the subject (226 papers) registered high-end citations (100+) per paper. The top 15 countries accounted for 87.05% of global publications output in the subject. The USA is in leadership position for its highest publications productivity (19.25% global share). The U.K. leads the world on relative citation index (2.05). International collaboration has been a major driver of AR research pursuits; between 11.89% and 44.04% of national share of top 15 countries in AR research appeared as international collaborative publications. AR research productivity by application types was the largest across sectors, such as education, industry and medical. Computer science has emerged as the most popular areas in AR research pursuits. Technical University of Munich, Germany and Osaka University, Japan have been the most productive organizations and Nara Institute of S&T, Japan (66.55 and 7.48) and Imperial College, London, U.K. (57.14 and 6.42) have been the most impactful organizations. M. Billinghurst and N. Navab have been the most productive authors and S. Feiner and B. MacIntyre have been the most impactful authors. IEEE Transactions on Visualization & Computer Graphics, Multimedia Tools & Applications and Virtual Reality topped the list of most productive journals.

• Journal of Biomedical Engineering Research
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• v.31 no.2
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• pp.134-140
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• 2010

Readily available high resolution brain MRI scans allow detailed visualization of the brain structures. Researchers have focused on developing methods to quantify shape differences specific to diseased scans. We have developed a novel method to quantify shape information for a specific population based on Multidimensional scaling(MDS). MDS is a well known tool in statistics and here we apply this classical tool to quantify shape change. Distance measures are required in MDS which are computed from pair-wise image registrations of the training set. Registration step establishes spatial correspondence among scans so that they can be compared in the same spatial framework. One benefit of our method is that it is quite robust to errors in registrations. Applying our method to 13 brain MRI showed clear separation between normal and diseased (Cushing's syndrome). Intentionally perturbing the image registration results did not significantly affect the separability of two clusters. We have developed a novel method to quantify shape based on MDS, which is robust to image mis-registration.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2013.06a
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• pp.167-170
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• 2013

의료 영상의 3차원 가시화는 최근에 교육 진단 수술 리허설 등의 목적으로 많은 관심을 받고 있다. 하지만 관심영역을 3차원으로 가시화 하는 작업은 복잡하고 시간이 많이 소요되는 과정이기 때문에, 대부분 ITK, VTK 같이 가시화 알고리즘이 구현된 오픈소스 라이브러리들이 사용되고 있다. 또한 인터페이스의 구현을 위해 Win32 API, MFC, Java SWT와 같은 플랫폼 또는 라이브러리들이 사용되고 있는 상황인데, 이러한 경향으로 인해 실제로 일련의 알고리즘을 모두 이해하고 직접 구현하는 경우는 거의 찾아보기 힘들다. 이에 본 논문은 의료 영상의 3차원 가시화를 위해 필요한 여러 기술들에 대해 설명하고, 이를 사용자와 상호작용 하는 인터페이스를 구현한 대화형 3차원 의료 가시화 소프트웨어를 구현하였다.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.253-256
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• 1995

Polymers have been one of the emerging biomedical materials in the area of biomedical research which are applicable to the human body. For human applications, noninvasive characterization of the biomedical polymers has been one of the important topics, and is valuable information. Among others, the swelling rate is one of the important measurements needed for the hydrophilic polymers. NMR imaging has been a suitable method for the noninvasive study of such a material since it is sensitive to many physical and biochemical changes of the specimens. In addition, NMR techniques possess many useful intrinsic properties such as the relaxation and diffusion effects. The present study has provided a noble and noninvasive method of measuring the process of swelling as well as volumetric changes occurred in polymers and drug delivery processes in a drug delivery system (DDS) together with changes of released drug. This gives information, relating with both water ingress process, volumetric changes of polymer specimens and the visualization of sequential drug delivery process. Also, this study provides more reliable method to ascertain the time dependent swelling process compared to the conventional method. The important aspects is that the proposed method is truly noninvasive and is able to ascertain time dependent processes.

• Journal of Biomedical Engineering Research
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• v.20 no.2
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• pp.155-164
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• 1999

In this paper, the prototype of SIS(Simulated Implantation System) for human femoral head is introduced. SIS is a software which carries on a virtual femoral head replacement surgery including 3d visualization as well as various numeric analyses between a patient's femur and artificial femur through certain stages of the image processing and of the computer graphics. Also, processes required after acquiring consecutive CT-images and projected image of an artificial femur are discussed, and the corresponding results including prototype of SIS are given.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.72-74
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• 1997

We have developed a 3-D image processing and display technique that include image resampling, modification of MIP, and fusion of MIP image and volumetric rendered image. This technique facilitates the visualization of the three-dimensional spatial relationship between vasculature and surrounding organs by overlapping the MIP image on the volumetric rendered image of the organ. We applied this technique to a MR brain image data to produce an MRI angiogram that is overlapped with 3-D volume rendered image of brain. MIP technique was used to visualize the vasculature of brain, and volume rendering was used to visualize the other structures of brain. The two images are fused after adjustment of contrast and brightness levels of each image in such a way that both the vasculature and brain structure are well visualized either by selecting the maximum value of each image or by assigning different color table to each image. The resultant image with this technique visualizes both the brain structure and vasculature simultaneously, allowing the physicians to inspect their relationship more easily. The presented technique will be useful for surgical planning for neurosurgery.

• 한국HCI학회:학술대회논문집
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• 2008.02b
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• pp.227-232
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• 2008

Since 2000, there have been many changes in the residential types, such as an intelligent apartment which integrates both resting space and production space with comfort able, pleasant and safe environments based on internet systems. As the result of the rapid decrease in the birth rate and the prolonged lifespan around the world, it is expected that we will enter into an aging society by 2026. With such the expected change in the living patterns, many issues concerning the increased number of the elderly people have emerged as major social problems such as changes of family formation, its function and values, responsibility of caring for the aged, health and medical care, habitation policies and so on, and it is required to reconsider the social awareness on the living qualities of each old person. However, we have not yet satisfied such requirements with appropriate policies for the improvement of the living environment for them. It is considered, therefore, that we need to develop a new tool that, according to our goals, can give us a broad understanding on several considerations in designing the future homes for the elder people, making it possible to check the process changed by residents' needs in real time and apply it immediately to the space. As we have seen, it is required that spatial design process and design methodology should be considered in designing the homes for the aged for the pre-occupancy design evaluation.