• Proceedings of the Plant Resources Society of Korea Conference
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• 2023.04a
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• pp.52-52
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• 2023

Ageing has been known to be deeply related to oxidative activities. Furthermore, inflammation is a response initiated by conditions such as infection and injury. It has been known that complex connections occur between oxidative stress and the inflammatory response, however underlying mechanism needs to be investigated. Chinese resource plants have been widely used as functional food and medicine for a long time, however it is not studied well how many of these resource plants work. We first decided testing anti-oxidant and anti-inflammatory activities with 95% ethanol extracts of the chinese resource plants, Boehmeria pilosinscula (Blume) Hassk., Carlemannia tetragona Hook f. and Clausena emarginata C.C.Huang. To measure anti-oxidant activity, we performed DPPH assay in Raw264.7 cells with 95% ethanol extracts. Clausena extracts showed significantly higher anti-oxidant activity than those of Boehmeria and Carlemannia. We then performed Nitric Oxide assay to measure the inflammation suppression levels with 95% ethanol extracts of these plants. Clausena extracts showed significantly higher suppression of nitric oxide production than those of Boehmeria and Carlemannia. This indicates that inflammation levels are significantly reduced by Clausena. After measuring anti-oxidant and anti-inflammatory activities, we then performed MTT assay to measure the cell survival rate of Raw264.7 cells treated with these extracts. Boehmeria showed much more cell survival rate than Carlemannia and Clausena. Taken together, this result suggests that Clausena extracts have more anti-oxidant and antiinflammatory activities than Boehmeria and Carlemannia, while Boehmeria extracts have more cell survival rate than Carlemannia and Clausena.

• Plant Resources
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• v.3 no.1
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• pp.79-89
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• 2000

This study was carried out to clarify the distribution of woody resource plants in Mts. Kyeryong, Bomoon and Shikiang in Taeion area, Korea. The woody plants, collected from April 1995 to August 1998, consist of total 347 taxa; 59 families,141 genera,275 species, one subspecies,56 varieties and 15 forms. The useful resource of woody plants were categorized as edible plant(128 taxa), medical plant(117 taxa), ornament plants(107 taxa), timber plants(38 taxa), pasturage(35 taxa) and industrial plant(20 taxa).

• Proceedings of the Korean Society of Crop Science Conference
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• 2003.05a
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• pp.10-16
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• 2003

Natural resource plants have been useful and helpful materials for human to against diseases and Prevention since ancient Egyptian and Roman times. However, according to recent survey, its habitat and indigenous are continuously decreased and almost extinct some valuable species, as Adonis vernalis, Digitalis lanata etc., especially in Eastern Europe and east Asian countries due to radical political and social reforms. ESCOP and FAO have already initiated to protect the endangered species for conservation, protection and propagation technology but it is not easy tasks without global concerning. Most natural resource plants have volatile components in essential oils and its consumption and demanding is increased every year, which contained certain compounds have no side effects and good properties for biological activities. Essential oils of natural resource plants are also well known for medical purposes, such as Central Nervous System (CNS, linalool), anticancer (d-limonene, perillyl alcohol, etc.), microbial and fungicidal activities (menthol, borneol, etc). Essential oil also used for natural therapy to prevent and increase immune systems instead of chemical synthesis drugs. With this, researchers of natural resource plants are ultimately faced to develop and optimal technology for increasing the Korean farmer's income by high added-value herbal products in present and future.

• Korean Journal of Plant Resources
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• v.7 no.2
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• pp.149-150
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• 1994

The plants medicinal resouces of middle area of Korea were investigated 10 times from May 1, 1993 to November 30. 1994. In order to analyze the vegetation of middle wild plants structure and distribu-tion. Medical wiId plants of middle southern area consisted of 100 familis, 380 specis in all. Theresources of important herb drugs were Polypodiaceae, Graminae, Liliaceae, Polygonaceae,Ranunculaceae, Brassicaceae, Rosaceae, Fabaceae, Apiaceae, Labiatae, Solanaceae, Scrophulariaceae,Campanulaceae, Compositae. The herb drugs were comparatively more than in other mountains in ourcountry.

• Plant Resources
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• v.2 no.2
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• pp.96-112
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• 1999

This study was to estimate and complete the flora of herbaceous plants found in Mt. Kyeryong National Park, Mt. Bomoon, and Mt. Shikjang in Taejon Korea. This research was conducted from April 1995 to August 1998. Herbaceous vascular plants were composed of 76 families,336 genera,574 species,4 subspecies, 105 varieties and 9 forms, totaling 691 taxa. The useful resource plants were categorized as edible plants (45.4%), medical plants (31.1%), pasture plants (28.7%), ornamental plants (16.4%) and industrial plants (1.6%).

• Proceedings of the Plant Resources Society of Korea Conference
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• 1999.10a
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• pp.84-89
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• 1999

The present study has been undertaken to detect edible medicinal plants with antineoplastic property on the basic of a number of traditional Korean medical literatures, besides studies on development of anti-cancer medical wild plants growing in Korea and to prove experimentally their efficacy by in vitro and in vivo tests.235 species from 45 family 79 genus were screened primarily as edible sources of antitumor effect. Among those the crude. extracts of 40 spp. showed considerable cytotoxicity in vitro and especially Pegangkuen(Patrinia scabiosaefolia), Deod-eog(Codonopsis lanceolata), Okssusu(Zea may), and Geureong(Eragrositis ferru-ginea) exhibited significant antitumor activity against sarcoma 180 asites mice. However, additional researches should be mode for the confirmation of their availability as antitumor plants.

• Korean Journal of Plant Resources
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• v.27 no.6
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• pp.680-686
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• 2014

Acanthopanacis Cortex has been used for oriental medicinal purposes in Asian countries especially in Korea and China. In the Korean Pharmacopeia, the cortexes of the dried roots, stems and branches of all species in Eleutherococcus and Eleutherococcus sessiliflorus are known as 'Ogapi'. Mostly the cortexes of E. gracilistylus roots and E.senticosus roots were used as 'Ogapi' in China and Japan, respectively. Therefore, the purpose of this study was to determine and compare the molecular authentication of Korean 'Ogapi' by using the ribosomal internal transcribed spacer (ITS) region. The ITS region has the highest possibility of effective and successful identification for the widest variety of molecular authentication. The ITS region was targeted for molecular analysis with Single nucleotide polymorphisms (SNPs) specific for morphologically similar to E. gracilistylus, E. senticosus, E. sessiliflorus from their adulterant, moreover, E. sieboldianus were detected within sequence data. Thus, based on these SNP sites, specific primers were designed and multiplex PCR analysis were conducted for molecular authentication of four plants (E. gracilistylus, E. senticosus, E. sessiliflorus, and E. sieboldianus). The findings of results indicated that ITS region might be established multiplex-PCR analysis systems and hence were proved to be an effective tools for molecular evaluation and comparison of 'Ogapi' with other plants.

• CELLMED
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• v.8 no.2
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• pp.8.1-8.5
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• 2018

Nitric oxide (NO) is a small diffusible molecule which plays an important role in various physiological activities. NO is a notable molecule, functioning as a cytotoxic agent and cellular messenger. There has been considerable interest in NO production by activated macrophages because this gaseous metabolite plays a fundamental role in the cytotoxic and cytostatic effects of macrophages towards invasive micro-organisms and tumour cells. No is a bioactive free radical that has been implicated in many physiological functions, plays a critical role during inflammation and therefore constitutes a potential target for developing therapeutics for inflammatory diseases. The use of medicinal plants by the population has been an important alternative the resource in the treatment of various diseases. Its growing acceptance in the medical community has been due to the fact that several plants with biological activities have been scientifically investigated and their efficacy and safety have been proven. In this review, discussed suppressive effects of No production by traditional medicines in RAW 264.7 and THP-1 macrophages.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.2311-2314
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• 2016

Pistagremic acid (PA) is a bioactive triterpenoid isolated from various parts of Pistacia integerrima plants. The aim of this research was to investigate PA for reversion of multidrug resistant (MDR) mediated by P-glycoprotein using rhodamine-123 exclusion study on a multidrug resistant human ABCB1 (ATP-binding cassette, sub-family B, member 1) gene-transfected mouse T-lymphoma cell line in vitro. Results were similar to those with verapamil as a positive control. Docking studies of PA and standard Rhodamine123 were carried out against a P-gp crystal structure which showed satisfactory results. Actually, PA cannot bind exactly where co-crystallized ligand of P-gp is already present. However, the docking study predicted that if a compound gives a lesser score then it may have some potency. The docking scores of PA and Rhodamine were similar. Therefore, we can conclude that there are certain important chemical features of PA which are responsible for the inhibiting potency of P-gp.

• Korean Journal of Plant Resources
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• v.33 no.5
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• pp.501-515
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• 2020

This study is attempted to prepare criteria to determine target species for conservation, through analyzing vascular flora and medicinal resources plants of Mt. Daedeok and Geumdae-bong in Gangwon Province, Korea. Flora Surveys were conducted 14 times from April, 2017 to October, 2019. Total 428 taxa with 83 families, 245 genera, 356 species, 5 subspecies, 46 varieties and 21 forms were distributed in Mt. Daedeok and Geumdae-bong. Korean endemic species were composed of 19 species. Total 36 taxa of Korean rare plants species were identified including 5 taxa in the degree of CR, 2 taxa in the degree of EN, 12 taxa in the degree of VU, 14 taxa in the degree of LC and 3 taxa in the degree of DD. The naturalized plants were 5 families, 10 genera, 10 species, totaling 10 taxa and medicinal resources plants were 239 taxa with 73 families, 185 genera, 239 species, 30 varieties 4 forms, 4 subspecies. The Urbanization Index (UI) was 2.5% and the Naturalized Index (NI) was 1.9%.