• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2023년도 임시총회 및 춘계학술대회
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• pp.52-52
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• 2023

Ageing has been known to be deeply related to oxidative activities. Furthermore, inflammation is a response initiated by conditions such as infection and injury. It has been known that complex connections occur between oxidative stress and the inflammatory response, however underlying mechanism needs to be investigated. Chinese resource plants have been widely used as functional food and medicine for a long time, however it is not studied well how many of these resource plants work. We first decided testing anti-oxidant and anti-inflammatory activities with 95% ethanol extracts of the chinese resource plants, Boehmeria pilosinscula (Blume) Hassk., Carlemannia tetragona Hook f. and Clausena emarginata C.C.Huang. To measure anti-oxidant activity, we performed DPPH assay in Raw264.7 cells with 95% ethanol extracts. Clausena extracts showed significantly higher anti-oxidant activity than those of Boehmeria and Carlemannia. We then performed Nitric Oxide assay to measure the inflammation suppression levels with 95% ethanol extracts of these plants. Clausena extracts showed significantly higher suppression of nitric oxide production than those of Boehmeria and Carlemannia. This indicates that inflammation levels are significantly reduced by Clausena. After measuring anti-oxidant and anti-inflammatory activities, we then performed MTT assay to measure the cell survival rate of Raw264.7 cells treated with these extracts. Boehmeria showed much more cell survival rate than Carlemannia and Clausena. Taken together, this result suggests that Clausena extracts have more anti-oxidant and antiinflammatory activities than Boehmeria and Carlemannia, while Boehmeria extracts have more cell survival rate than Carlemannia and Clausena.

• Plant Resources
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• 제3권1호
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• pp.79-89
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• 2000

This study was carried out to clarify the distribution of woody resource plants in Mts. Kyeryong, Bomoon and Shikiang in Taeion area, Korea. The woody plants, collected from April 1995 to August 1998, consist of total 347 taxa; 59 families,141 genera,275 species, one subspecies,56 varieties and 15 forms. The useful resource of woody plants were categorized as edible plant(128 taxa), medical plant(117 taxa), ornament plants(107 taxa), timber plants(38 taxa), pasturage(35 taxa) and industrial plant(20 taxa).

• 한국작물학회:학술대회논문집
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• 한국작물학회 2003년도 춘계 학술대회지
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• pp.10-16
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• 2003

Natural resource plants have been useful and helpful materials for human to against diseases and Prevention since ancient Egyptian and Roman times. However, according to recent survey, its habitat and indigenous are continuously decreased and almost extinct some valuable species, as Adonis vernalis, Digitalis lanata etc., especially in Eastern Europe and east Asian countries due to radical political and social reforms. ESCOP and FAO have already initiated to protect the endangered species for conservation, protection and propagation technology but it is not easy tasks without global concerning. Most natural resource plants have volatile components in essential oils and its consumption and demanding is increased every year, which contained certain compounds have no side effects and good properties for biological activities. Essential oils of natural resource plants are also well known for medical purposes, such as Central Nervous System (CNS, linalool), anticancer (d-limonene, perillyl alcohol, etc.), microbial and fungicidal activities (menthol, borneol, etc). Essential oil also used for natural therapy to prevent and increase immune systems instead of chemical synthesis drugs. With this, researchers of natural resource plants are ultimately faced to develop and optimal technology for increasing the Korean farmer's income by high added-value herbal products in present and future.

• 한국자원식물학회지
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• 제7권2호
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• pp.149-150
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• 1994

The plants medicinal resouces of middle area of Korea were investigated 10 times from May 1, 1993 to November 30. 1994. In order to analyze the vegetation of middle wild plants structure and distribu-tion. Medical wiId plants of middle southern area consisted of 100 familis, 380 specis in all. Theresources of important herb drugs were Polypodiaceae, Graminae, Liliaceae, Polygonaceae,Ranunculaceae, Brassicaceae, Rosaceae, Fabaceae, Apiaceae, Labiatae, Solanaceae, Scrophulariaceae,Campanulaceae, Compositae. The herb drugs were comparatively more than in other mountains in ourcountry.

• Plant Resources
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• 제2권2호
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• pp.96-112
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• 1999

This study was to estimate and complete the flora of herbaceous plants found in Mt. Kyeryong National Park, Mt. Bomoon, and Mt. Shikjang in Taejon Korea. This research was conducted from April 1995 to August 1998. Herbaceous vascular plants were composed of 76 families,336 genera,574 species,4 subspecies, 105 varieties and 9 forms, totaling 691 taxa. The useful resource plants were categorized as edible plants (45.4%), medical plants (31.1%), pasture plants (28.7%), ornamental plants (16.4%) and industrial plants (1.6%).

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 1999년도 The 6th International Symposium on the Development of Anti-Cancer Resource from Plants
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• pp.84-89
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• 1999

The present study has been undertaken to detect edible medicinal plants with antineoplastic property on the basic of a number of traditional Korean medical literatures, besides studies on development of anti-cancer medical wild plants growing in Korea and to prove experimentally their efficacy by in vitro and in vivo tests.235 species from 45 family 79 genus were screened primarily as edible sources of antitumor effect. Among those the crude. extracts of 40 spp. showed considerable cytotoxicity in vitro and especially Pegangkuen(Patrinia scabiosaefolia), Deod-eog(Codonopsis lanceolata), Okssusu(Zea may), and Geureong(Eragrositis ferru-ginea) exhibited significant antitumor activity against sarcoma 180 asites mice. However, additional researches should be mode for the confirmation of their availability as antitumor plants.

• 한국자원식물학회지
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• 제27권6호
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• pp.680-686
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• 2014

Acanthopanacis Cortex has been used for oriental medicinal purposes in Asian countries especially in Korea and China. In the Korean Pharmacopeia, the cortexes of the dried roots, stems and branches of all species in Eleutherococcus and Eleutherococcus sessiliflorus are known as 'Ogapi'. Mostly the cortexes of E. gracilistylus roots and E.senticosus roots were used as 'Ogapi' in China and Japan, respectively. Therefore, the purpose of this study was to determine and compare the molecular authentication of Korean 'Ogapi' by using the ribosomal internal transcribed spacer (ITS) region. The ITS region has the highest possibility of effective and successful identification for the widest variety of molecular authentication. The ITS region was targeted for molecular analysis with Single nucleotide polymorphisms (SNPs) specific for morphologically similar to E. gracilistylus, E. senticosus, E. sessiliflorus from their adulterant, moreover, E. sieboldianus were detected within sequence data. Thus, based on these SNP sites, specific primers were designed and multiplex PCR analysis were conducted for molecular authentication of four plants (E. gracilistylus, E. senticosus, E. sessiliflorus, and E. sieboldianus). The findings of results indicated that ITS region might be established multiplex-PCR analysis systems and hence were proved to be an effective tools for molecular evaluation and comparison of 'Ogapi' with other plants.

• 셀메드
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• 제8권2호
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• pp.8.1-8.5
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• 2018

Nitric oxide (NO) is a small diffusible molecule which plays an important role in various physiological activities. NO is a notable molecule, functioning as a cytotoxic agent and cellular messenger. There has been considerable interest in NO production by activated macrophages because this gaseous metabolite plays a fundamental role in the cytotoxic and cytostatic effects of macrophages towards invasive micro-organisms and tumour cells. No is a bioactive free radical that has been implicated in many physiological functions, plays a critical role during inflammation and therefore constitutes a potential target for developing therapeutics for inflammatory diseases. The use of medicinal plants by the population has been an important alternative the resource in the treatment of various diseases. Its growing acceptance in the medical community has been due to the fact that several plants with biological activities have been scientifically investigated and their efficacy and safety have been proven. In this review, discussed suppressive effects of No production by traditional medicines in RAW 264.7 and THP-1 macrophages.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2311-2314
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• 2016

Pistagremic acid (PA) is a bioactive triterpenoid isolated from various parts of Pistacia integerrima plants. The aim of this research was to investigate PA for reversion of multidrug resistant (MDR) mediated by P-glycoprotein using rhodamine-123 exclusion study on a multidrug resistant human ABCB1 (ATP-binding cassette, sub-family B, member 1) gene-transfected mouse T-lymphoma cell line in vitro. Results were similar to those with verapamil as a positive control. Docking studies of PA and standard Rhodamine123 were carried out against a P-gp crystal structure which showed satisfactory results. Actually, PA cannot bind exactly where co-crystallized ligand of P-gp is already present. However, the docking study predicted that if a compound gives a lesser score then it may have some potency. The docking scores of PA and Rhodamine were similar. Therefore, we can conclude that there are certain important chemical features of PA which are responsible for the inhibiting potency of P-gp.

• 한국자원식물학회지
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• 제33권5호
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• pp.501-515
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• 2020

본 연구는 대덕산·금대봉 생태계보전지역 내 분포하는 관속 식물상을 파악하여 식물분포를 밝히고, 향후 대덕산-금대봉 생태계보전지역의 주요 식물에 대한 효율적인 관리와 보전을 위해 수행하였다. 2017년 4월부터 2019년 10월까지 총 14회에 걸쳐 현지조사를 실시하였다. 대덕산-금대봉 생태계보전지역에 자생하는 관속식물상은 83과 245속 372종 4아종 45변종 8품종으로 총 428분류군이 조사되었다(Appendix 1). 이 중 한국특산식물은 키버들, 참개별꽃, 진범, 갈퀴현호색 등 19분류군이며, 환경부지정 희귀 및 멸종위기 식물은 개병풍, 가시오갈피, 대성쓴풀, 복주머니란으로 총 4분류군이 조사되었고, 산림청 지정 희귀식물은 19과 34속 34종 2변종 총 36분류군이 나타났다. 침입외래식물은 토끼풀, 달맞이꽃, 지느러미엉겅퀴 등 4과 8속 8종 총 8분류군으로 조사되었으며. 도시화지수(UI)는 2.5%, 귀화율(NI)은 1.9%로 나타났다. 본 조사지역의 양치식물은 7과 9속 7종 2변종으로 총 9분류군이 나타났고, 양치식물계수는 0.52로 나타났다. 대한약전 기준 약용자원식물은 16과 24속 24종 2변종 1품종 27분류군이 확인되었다. 민속식물은 772과 175속 216종 28변종 3품종 4아종 251분류군이 확인되었으며, 대덕산·금대봉에서 출현한 428분류군 중 58.6%가 민속식물로 나타났다. 민속식물을 분류 별로 보면 가장 많은 213분류군이 식용식물로 분류되었다. 약용식물은 161분류군이었으며, 향신용식물은 11분류군으로 나타났다. 환경부에서 멸종위기 식물로 지정된 대성쓴풀과 복주머니란 등의 희귀식물은 시급히 보호 및 보전에 필요한 대책을 마련해야 할 것으로 판단되며, 나도범의귀는 북방계식물로 남한 내 자생지가 검룡소 1곳이 보고되고 있어 자생지보호의 필요성이 있을 것으로 판단된다.