• 대한족부족관절학회지
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• 제9권1호
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• pp.20-25
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• 2005

Purpose: To determine the locations and incidences of sesamoids and accessory bones of the forefoot in normal Korean adults. Materials and Methods: The plain radiographs of the forefoot of 400 volunteers, 200 males and 200 females, were taken. The three orthopedic surgeons participated in the radiographic evaluation independently. Persons who had history of foot problem or injury were excluded. Results: Sesamoids of first metatarsophalangeal joint were nearly always present; medial 99% and lateral 100%. The bipartite sesamoid was more common in medial (9.8%) and in female (17.0%) than in lateral (0.3%) and in male (2.5%). Sesamoids of the interphalangeal joint of the first toe were seen in 35.8%. Sesamoids of metatarsophalangeal joints in other four toes were rarely observed. Their incidences were 5% in second toe, 0.8% in third, 0% in fourth, and 2.8% (lateral) and 7.5% (medial) in fifth. Sesamoids of interphalangeal joint in four lesser toes were not observed except two cases (0.5%) in the fifth toe. Accessory bone was very rarely observed. Os vesalianum was observed in five feet (1.3%), Os intermetatarseum in 14 feet (3.5%), and Os cuneo-metatarsal I tibiale in none. Conclusion: We determined the location and incidences of sesamoids and accessory bones of the forefoot, and we expected this to help to diagnose the forefoot problem.

• 한국한의학연구원논문집
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• 제15권1호
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• pp.1-11
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• 2009

The eminent brother doctors Cho-Gaek Hur (Young Hur) and Cho-Sam Hur (Eon Hur) represent the medical tradition of the southeastern region of Mt. Jirisan incluiding Sancheong. This study investigated and examined their herediatary testimonies and medico-historical facts described in the literature tale, genealogy and family collection of works. At an early age after their family run away to the southern region from the harm of political struggle, they gave up taking the highest-level state examination to recruit ranking officials and set their heart on learning medicine. Their choice of medicine was the second best plan for the survival of their family and descendents from the influence of their ancestors who suffered from the party strife during the late Joseon Dynasty. The case is a good example of the deliberate action of the nobility intellectuals since the late Goryeo and early Joseon dynasties to who made attempts to have the minimum elegance and cause while securing livelihood after they have been collapsed politically. The tale of Cho-Gaek and Cho-Sam is a typical story of eminent doctors which combined reality and fiction about the persons who had outstanding medical skills. In the tale, the elder brother was good at herbal prescriptions and the younger brother was good at acupuncture, contrasting the treatment of administrative internal medicine and insertive acupuncture treatment. It shows that the prepositions for the choice of the treatment method for the public during that period were safety and fast efficacy. In their old age, they wrote a book titled Jinyangsinbang. Another Jinwoosinbang is estimated as a different kind of copy, which was a medical writing from experience that derived from the same original book as Jinyangsinbang. written by Cho-Gaek Hur and it is a valuable medical material that possesses the distinct features of the local medicine during the late Joseon Dynasty. Most of the contents are variations in application using the basis of Dongeuibogam, forming the roots of the traditional Korean medicine in Sancheong region together with the medical activities of the Hur brothers.

• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7419-7424
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• 2014

Gliomas are the most common type of primary brain tumors. The XRCC1 Arg194Trp variant affects the proliferating cell nuclear antigen(PCNA) binding region, which suggests that this mutation may contribute to gliomagenesis and a number of articles have examine the association between XRCC1 Arg194Trp and the susceptibility to glioma. However, the results were conflicting. Test of heterogeneity, sensitivity analysis, meta-analysis, and assessment of publication bias were all performed in our present meta-analysis, covering a total of 5,407 patients and 7,715 healthy persons. In the overall analysis the XRCC1 Arg194Trp polymorphism showed a significant association with glioma susceptibility in a recessive mode l(for TrpTrp vs ArgArg+ArgTrp: OR=1.918, 95%CI=1.575-2.336, $I^2$=2.3%). In addition, analysis of subgroups presented an increased risk in Asians and populations-based on hospitals. The results suggested that the XRCC1 Arg194Trp polymorphism is a genetic risk factor for glioma, especially in Asian population. To further evaluate gene-gene and gene-environment interactions on XRCC1 polymorphisms and glioma risk, thousands of subjects and tissue-specific biochemical characterizations are required.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.407-412
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• 2016

Background: Considering the rising incidence of thyroid cancer worldwide, the aim of our study was to investigate the temporal trends in the incidence of this cancer in a large population of Iranian patients. Materials and Methods: We used the Iran Cancer Data System (ICDS) Registry to assess the thyroid cancer trend from 2004 to 2010 with regard to different genders, age groups, and morphologies. To do this we analyzed the data of 10,913 new cases of thyroid cancer that occurred during these years. Results: The incidence rate (per one year) of thyroid cancer was 2.20 per 100,000 persons between 2004 and 2010 in Iran. Papillary thyroid cancer was the most common histology type, with an annual rate of 0.29 in Iran. The highest rate of prevalence in thyroid cancer was observed at the age of 45 years at the time of diagnosis. We found a female-to-male ratio of 2 in Iran. A significant decrease was detected in the trend of thyroid cancer in children <19y, which was not correlated to the trend of older patients. Conclusions: As expected, the trend of thyroid cancer increased over the 7 years, primarily contributed by papillary thyroid cancer. A rising pattern of incidence was seen in all the age groups except patients aged under 19 years.

• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3273-3277
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• 2015

Network scale up (NSU) is a novel approach to estimate parameters in hard to reach populations through asking people the number of individuals they know in their active social network. Although the method have been used in hidden populations, advantages of NSU indicate that exploration of applicability to disease like cancer might be feasible. The aim of this study was to assess the application of NSU to estimate the size of the population of breast, ovarian/cervical, prostate, and bladder cancers in the South-east of Iran. A total of 3,052 (99% response rate) Kermanian people were interviewed in 2012-2013. Based on NSU, participants were asked about if they know any people on their social network who suffered from breast, ovarian/cervical, prostate, and bladder cancers, if yes, they should enumerate them. A total of 1,650 persons living with four types of cancers (breast, ovary/cervix, prostate, and bladder) were identified by the respondents. Totally, the prevalence of people living with the four types of cancers was 228.4 per 100,000 Kermanian inhabitants. The most prevalent cancer was breast cancer, at 168.9 per 100,000, followed by prostate cancer with 116.9, ovarian/cervical cancer with 99.8, and bladder cancer with 36.3 per 100000 Kerman city population. NSU values provide a usable but not very precise way of estimating the size of subpopulations in the context of the four major cancers (breast, ovary/cervix, prostate, and bladder).

• Journal of Acupuncture Research
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• 제27권2호
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• pp.71-78
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• 2010

Objectives : This survey was accomplished to find out how Korean medical doctors take Ojeok-san prescriptions for low back pain in clinical practice. Methods : The survey questionnaire was developed by the committee of experts who major in acupuncture & moxibustion or statistics for acupuncture clinical trial protocol development. 306 persons having more than 5 years experience were randomly selected from a list of Korean medical doctors. Telephone interviews with them were conducted by the well-trained interviewers between March 21 and April 4 in 2009 and the computerized data were analyzed by STATA 9.0 SE version(Stata Corp, Colleg Station Tex, USA) statistical program. Results : 1. 192 out of 306(65.1%) Korean medical doctors taked Ojeok-san prescriptions for musculoskeletal disorders patients and 183 out of 192(95.3%) Korean medical doctors taked Ojeok-san prescriptions for low back pain treatment. 2. The rate of low back pain patients, '20~30%' was 99 people(33.6%) and the rate of Ojeok-san prescriptions for low back pain treatment, 'below 10%' was 65 people(35.5%). 3. In Ojeok-san effect of low back pain treatment, 'greate effects' 29.5%, 'tolerable effects' 66.7%, 'no effects' 3.8% were selected. In granule extracts effect, 'similar to Original herbs' 9.8%, 'unlike to Original herbs' 90.2% were selected. Conclusions : In our telephone survey, Korean medical doctors taked Ojeok-san prescriptions for low back pain treatment. Further research on this issue is needed.

• 한국병원경영학회지
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• 제16권4호
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• pp.85-110
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• 2011

As Gangwon-do Province needs an environmental-friendly alternative tourism according to low carbon green growth, this study analyzes specialized fields in green health industry, selects seven specialized fields in green health industry that is fit to Gangwon-do Province, and suggests a development strategy by conducting recognition surveys on preference and impotence of the specialized fields. Surveys and interviews are conducted of 106 students at Green Health Industry Education Center which is operating by Kwandong University and 84 persons who work at medical institutions and tourism related companies in Ganwondo. The surveys and interviews were completed from November 5 to November 19 in 2010, determined factors through a factor analysis when they have many questions, and analyzed by using SPSS 14.0. Out of the seven specialized fields, rest & recuperation field is highly recognized. In order to have competitive edge compared to other self-governing provinces, Ganwon-do Province should prioritize rest and recuperation field. A healthcare program in the green health industry specific to Ganwon-do Province includes hot springs and spa programs as a priority. Gangwon-do's hot springs are deemed to be competitive resources as global medical tourists prefer spa and sauna healthcare programs, while the province promotes its spring resources and builds medical tourism infrastructures. Gangwon-do Province can promote a medical tourism industry that is well suitable for the strength and characteristics of the province. It might pursue oriental medicine therapy tourism, which is related to a recuperating medical service that uses both oriental and western medicine. It can also run such programs as forest bathing (oxygen road), spring and spa, and sea water treatment, which are the specialized fields in green health industry with respect to recreation and healthcare.

• 보건교육건강증진학회지
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• 제18권1호
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• pp.93-108
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• 2001

The purpose of this study was to identify the factors that affected to physical functions, activities of daily living (ADLs) and instrumental activities of daily living (IADLs). The subjects for this study, 236 persons, 65 years and over, who were living at rural area in Chun-Cheon city. This survey was carried out from march 3rd to April 25th, 1998. The data was analysed by using SPSS PC+ program. The results were as follows. 1.The variables that were related to the conditions of physical functions were as follows; age, sex, educational level among the general characteristics; raising ways of money, monthly using money for life, states of pocket money, obtaining method of pocket money, state of weight, problems in mind, whether or not chronic illness among socio ㆍeconoㆍphysical conditions; the level of satisfactions in life, subjective condition of health among the subjective thinking ; controlling state in smoking and drinking of alcohol among the lifestyles for promoting health. But the variables for medical utilization were not related to the level of physical function. 2. The variables that were associated with the condition of ADLs were as follows; age among the general characteristics; monthly using money for life, working amount among the socioㆍeconoㆍphysical conditions; subjective conditions of health among the subjective thinking. But The variables for medical utilization, lifestyle for promoting health were irrelevant to the conditions of ADLs. 3. The variables that were related to the conditions of IADLs were as follows; age, educational level among the general characteristics; raising ways of money, monthly using money for life, resident type in the household, procurement method of pocket money, level of weight, problems in mind, wether or not chronic illness among socioㆍeconoㆍphysical condition; regularity of health checking among lifestyles for promoting health; kinds of utilizing medical agent among the variables about utilization patterns of medical agencies; subjective condition of health among the subjective thinking In this study, in the aged there were related factors of physical and life functions, were age, working amount, subjective condition of health.

• 대한한의학회지
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• 제18권1호
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• pp.40-57
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• 1997

연구배경(硏究背景) 및 목적(目的) 최근(最近) 한방공중보건사업(韓方公衆保健事業)에 대(對)한 연구(硏究)와 제도개선(制度改善)이 이루어지면서, 한방의료시혜(韓方醫療施惠)를 통(通)해 국민(國民)들의 보건지도(保健指導) 및 건강증진(健康增進) 향상(向上)에 많은 영향(影響)을 끼칠 것으로 보인다. 1995년(年)부터 1년여(年餘)에 걸쳐 한방병원(韓方病院)과 보건소(保健所)가 함께 보건소내(保健所內) 한방의료(韓方醫療)를 실시(實施)하면서 주민(住民)들로부터 많은 호응(呼應)을 받았다. 이에 보건소(保健所)에 내원(來院)하여 한방진료(韓方診療)를 받은 환자(患者)들의 일반적(一般的)인 특징(特徵)과 질환(疾患)의 특성(特性) 및 치료효과(治療效果) 등(等)에 대(對)하여 조사(調査)하였다. 대상(對象) 및 방법(方法) 1996년(年) 1월(月) 4일(日)부터 1996년(年) 12월(月) 26일(日)까지 1년간(年間) 전라북도(全羅北道) 전주시(全州市) 완산구(完山區) 보건소(保健所)에서 주(週) 1회(回) 또는 3회(回)에 걸쳐 총(總) 60회(回)동안 실시(實施)한 한방진료(韓方診療)를 받은 환자(患者) 234명(名)의 질환(疾患) 234건(件)을 대상(對象)으로 통계연구(統計硏究)하였다. 결과(結果) 및 결론(結論) 1. 환자(患者)의 남녀비율(男女比率)은 1 : 6.8로 여성(女性)이 월등(越等)히 많았다. 2. 환자중(患者中) 51세이상(歲以上)이 88.89%로 고령환자(高齡患者)가 대부분(大部分)을 차지했다. 3. 총질환(總疾患) 238건중(件中) 근골격계(筋骨格系) 및 결합조직질환(結合組織疾患)이 82.77%로 대부분(大部分)을 차지했다. 4. 병력기간(病歷期間)은 1년(年)에서 5년(年)사이가 32.35%로 가장 높아 관련질환(關聯疾患)이 만성화(慢性化)상태임을 알려준다. 5. 초진시(初診時) 증상(症狀)은 심(甚)한 자각증상(自覺症狀)을 갖고 생활(生活)에 많은 지장을 초래(招來)하는 경우(境遇)(Grade III)가 55.88%로 가장 많았다. 6. 양호이상(良好以上)의 치료효과(治療效果)를 보인 경우(境遇)는 62.18%였고, 저효이상(抵效以上)의 효과(效果)는 78.99%로 나타났다. 7. 치료기간(治療期間)을 2회(回)에서 5회(回) 내원(來院)하여 치료(治療)받은 경우(境遇)가 34.03%로 가장 높았고, 1회(回)만 내원(來院)한 경우(境遇)에 비(比)하여 2회(回)에서 10회(回) 내원(來院)하여 치료(治療)받은 환자(患者)들이 4배정도(倍定度)의 높은 치료율(治療率)을 보였다. 8. 처방(處方)은 오적산(五積散), 팔미환(八味丸), 향사평위산(香砂平胃散), 소경활혈탕(疎經活血湯), 육미지황탕(六味地黃湯) 등(等)의 순(順)으로 많이 사용(使用)되었다. 9. 침(針)은 1일평균(日平均) 22.58명(名)을 시술(施術)하였고, 구(灸)(뜸)는 1일평균(日平均) 0.58명(名)을, 사혈(瀉血)은 1일평균(日平均) 2.28명(名)을 시술(施術)하였다. 10. 한양방향시치료시(韓洋方同時治療時) 양호이상(良好以上)의 효과(效果)를 보인 경우(境遇)가 30건중(件中) 21건(件)으로 70%의 치료효과(治療效果)를 보여 한방단일진료시(韓方單一診療時)보다 다소 높은 치료효과(治療效果)를 나타냈다. 11. 1일평균(日平均) 한방진료건수(韓方診療件數)는 26.95명(名)이었고, 1일평균(日平均) 한방초진환자수(韓方初診患者數)는 3.9명(名)으로 나타났으며, 한방진료(韓方診療)가 양한방(洋韓方) 총진료(總診療)의 23.20%를 차지했고, 1일(日) 평균(平均) 한양방(韓洋方) 총진료건수(總診療件數)에 대(對)해 1일(日) 평균(平均) 한방초진건수(韓方初診件數)가 21.51%를 차지하는 것으로 나타났다.

• 한국산학기술학회논문지
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• 제15권8호
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• pp.5124-5130
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• 2014

조영제의 희석률 변화에 따른 신호강도를 분석하여 조영증강 자기공명혈관조영검사 시 점도와 삼투압에 따른 부작용을 최소화하고 신호강도를 높여 영상의 질을 향상시키고자 하였다. 연구방법은 조영제가 혈관에 주입되면 혈액과 희석되어 mol 농도가 변화되고, 그에 따라 신호강도의 변화를 일으킴에 착안하여 phantom을 제작하였다. phantom 결과를 바탕으로 임상실험은 2013년 11월부터 2014년 1월까지 조영제를 희석한 군(30명)과 희석하지 않은 군(30명)으로 구분하여 뇌혈관의 신호강도를 비교하였다. 연구결과, 조영제 mol 농도 변화에 따른 phantom의 신호강도는 0.0125mmol부터 급격히 증가하다 20mmol에서 최고점을 이룬 후 200mmol부터 평형을 이루었다. 임상실험에서도 조영제를 희석하여 검사한 영상의 신호강도가 모두 높게 나타나, 1000mmol 조영제 사용에 비해 500mmol로 희석하여 사용함이 최고점인 20mmol에 근접하여 우수함을 알 수 있었다. 결론적으로 조영제를 희석하여 사용함으로써 점도와 삼투압을 저하시키고, 영상의 질을 향상시킬 수 있었으므로 임상적용의 유용성이 높다고 할 수 있다.