• Title/Summary/Keyword: Medical papers

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Comparisons of Certification Standards for Mask and Review on Filtration Efficiency for Viruses (마스크의 인증기준 비교와 바이러스 여과효율에 대한 고찰)

  • Yoon, Chungsik;Go, Sulbee;Park, Jihoon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.30 no.2
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    • pp.109-123
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    • 2020
  • Objectives: The aims of this study were to review the standards and key components of the standards for disposable masks in Korea, the US, EU, Japan, and China and to evaluate the appropriateness of disposable masks during a virus pandemic. Methods: We reviewed the standards in the above countries and compared their key elements for each standard. For the second purpose, systemic paper gathering using key words like 'mask', 'respirator' 'virus', and 'coronavirus' in the PubMed search engine was performed. Fifty-three papers were selected and reviewed in regard to the appropriateness of test protocols with sodium chloride(NaCl) particles for virus filtration and the effectiveness against viruses. Results: The standards for masks are largely divided into two categories: US standards and EU standards. In Korea, the Ministry of Employment and Labor adapted the EU standards for workers and the Health Masks adopted the Ministry of Employment and Labor standards by the Ministry of Food and Drug Safety. Regarding airborne viral infections, WHO emphasizes only droplet infection, while many studies have shown that small particles enter the air through coughing or sneezing, which increases the possibility of airborne infection. Compared to other particles, various factors such as airborne viability and the ability to replicate the virus in the body are further involved in the virus's airborne infection rate. Airborne infection is classified into absolute air infection, preferential air infection, and opportunistic air infection. The NaCl-certified N95 mask showed good filtration efficiency against viruses and NaCl particles were proved to be a surrogate material for viruses. From this, KF94 is also expected to be effective in blocking viruses. Conclusion: The N95 test method could be used as a surrogate test method for virus filtration. N95-class masks have been found to effectively block viral infections in the air. However, surgical or medical masks are only partially effective against airborne virus infection though they could effectively block large droplet infection. However, most studies considered in this study targeted N95 in foreign countries and studies on masks actually used in Korea are very limited, so studies on microorganisms and reuse on domestic masks should be conducted in the future.

A Comparative Analysis of the Systems Related to the Production, Authorization, and Listing for Insurance of Herbal Medicine Products in South Korea and Taiwan (국내와 대만의 전통약제제 생산.허가.보험등재 관련 제도)

  • Son, Chi-Hyoung;Lim, Sabina;Lee, Eun-Kyoung;Kim, Dong-Su;Kim, Yun-Gi;Cheng, Huan-Chiang;Kim, Yong-Ho
    • The Journal of Korean Medicine
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    • v.33 no.3
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    • pp.147-159
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    • 2012
  • Objectives: Systems related to the production, authorization, and listing for insurance of herbal medicine products were compared between South Korea and Taiwan to illuminate herbal medicine products system issues in South Korea. Methods: Papers, and laws and policies related to the production, authorization, and listing for insurance of herbal medicine products in South Korea and Taiwan are analyzed to create the primary documents. The documents from South Korea were screened with the advice of a specialist, while those from Taiwan have been verified through local investigation and with the help of a related specialist. The screened documents were then compared and analyzed in the order of the systems related to the production, authorization, and listing for insurance of herbal medicine products. Results: The systems related to the production of herbal medicine products satisfy GMP requirements in both countries, while Taiwan has more specialized systems related to the production of herbal medicine products and a more strict authorization program as compared to South Korea. While South Korea has most of the herbal medicine products classified as non-prescription drugs, Taiwan has them as prescription drugs. And while South Korea does not allow new herbal medicine products to be listed for insurance, Taiwan allows for once-a-year application toward listing for insurance. Conclusions: In order to ensure the safe and effective use of herbal medicine products, systems related to the production, authorization, and listing for insurance of herbal medicine products are to be established, while the categorization of medicine products principally used by Korean medicine doctors should be prepared. Furthermore, prescription by a Korean medicine doctor for new drugs made with natural products and their listing for insurance need to be encouraged.

Risk Factors Related with Mortality in Patient with Pulmonary Tuberculosis

  • Kim, Chong Whan;Kim, Sang-Ha;Lee, Shun Nyung;Lee, Seok Jeong;Lee, Myoung Kyu;Lee, Ji-Ho;Shin, Kye Chul;Yong, Suk Joong;Lee, Won Yeon
    • Tuberculosis and Respiratory Diseases
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    • v.73 no.1
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    • pp.38-47
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    • 2012
  • Background: The prevalence rate of pulmonary tuberculosis (PTB) is steadily decreasing in South Korea. However, PTB is a disease with relatively high mortality and morbidity rates throughout Korea. Although there are many studies and statistics about the risk factors of PTB mortality in many countries, there are only a limited number of domestic papers on this topic. The aim of this study is to determine predictive factors for mortality among in-hospital patients associated with PTB. Methods: From December 2006 to January 2011, we reviewed medical records of 2,122 adult patients diagnosed with tuberculosis at a single tertiary hospital in a suburban area. In this study period, 960 patients were diagnosed with PTB by positive Acid fast bacilli smear and/or mycobacterial culture of the respiratory specimen. We compared the groups of patients deceased and patients discharged alive with PTB. The number of dead patients was 82 (47 males, 35 females). Results: Mortality was significantly associated with increased values of white blood cells (WBC), blood urine nitrogen (BUN), creatinine, C-reactive protein (CRP), numbers of involved lung field, and length of hospitalization. Also, it was associated with the decreased values of hemoglobin, lymphocyte, sodium, albumin, and cholesterol. Furthermore, admission through the emergency department, initial intensive care unit admission, and drug resistant PTB affected mortality in PTB patients. Independent predictors associated with PTB mortality are BUN, initial intensive care unit care, and admission during treatment of tuberculosis. Conclusion: In our study, mortality of pulmonary tuberculosis was related with parameters associated with nutritional status, disease severity at the time of admission, and drug resistance.

Effective Performance Analysis of Disease-oriented Translational Research from a Point of View of Biotechnology (생명공학기술적 관점에서 질병중심 중개연구의 효율적 성과분석에 대한 실증연구)

  • Cheon, Su-Hwan;Jung, Sung-Chul;Je, Young-Tae;Kim, Gi-Tae;Kim, Myung-Hwan;Park, Seong-Ho;Jeon, Hye-Kyoung;Kwon, Jun-Young;Kim, Dong-Il;Kim, Dong-Seok;Lee, Kyung-Min;Sun, Kyung
    • KSBB Journal
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    • v.27 no.1
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    • pp.1-8
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    • 2012
  • Recently, translational research (TR) in health technology (HT) has been considered as an emerging alternative research system for the improvement of human health. TR from bench to bedside involves a strong bidirectional relationship between basic science discovery and clinical practice. To support R&D planning and policy in HT effectively, the performance of TR programs was analyzed and evaluated in a R&D project on health and medical technology. TR programs were classified into three parts: unilateral TR, bilateral TR and multilateral TR. Bibliometrics and citation analysis were performed to assess research papers and gather information for the performance analysis of TR programs. In addition, both quantitative and qualitative analysis were successfully carried out using ISI Web of Science, Google Scholar Citations, SCOPUS and Knowledgematrix. In conclusion, the performance analysis of TR programs could significantly improve the efficiency of R&D plans, R&D management and evaluation for a safe and healthy life.

Trend of Research and Industry-Related Analysis in Data Quality Using Time Series Network Analysis (시계열 네트워크분석을 통한 데이터품질 연구경향 및 산업연관 분석)

  • Jang, Kyoung-Ae;Lee, Kwang-Suk;Kim, Woo-Je
    • KIPS Transactions on Software and Data Engineering
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    • v.5 no.6
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    • pp.295-306
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    • 2016
  • The purpose of this paper is both to analyze research trends and to predict industrial flows using the meta-data from the previous studies on data quality. There have been many attempts to analyze the research trends in various fields till lately. However, analysis of previous studies on data quality has produced poor results because of its vast scope and data. Therefore, in this paper, we used a text mining, social network analysis for time series network analysis to analyze the vast scope and data of data quality collected from a Web of Science index database of papers published in the international data quality-field journals for 10 years. The analysis results are as follows: Decreases in Mathematical & Computational Biology, Chemistry, Health Care Sciences & Services, Biochemistry & Molecular Biology, Biochemistry & Molecular Biology, and Medical Information Science. Increases, on the contrary, in Environmental Sciences, Water Resources, Geology, and Instruments & Instrumentation. In addition, the social network analysis results show that the subjects which have the high centrality are analysis, algorithm, and network, and also, image, model, sensor, and optimization are increasing subjects in the data quality field. Furthermore, the industrial connection analysis result on data quality shows that there is high correlation between technique, industry, health, infrastructure, and customer service. And it predicted that the Environmental Sciences, Biotechnology, and Health Industry will be continuously developed. This paper will be useful for people, not only who are in the data quality industry field, but also the researchers who analyze research patterns and find out the industry connection on data quality.

Interstitial Pneumonia and Lung Cancer Surgery (간질성 폐렴과 폐암수술)

  • Sa Young-Jo;Wang Young-Pil;Park Jae-Kil
    • Journal of Chest Surgery
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    • v.39 no.4 s.261
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    • pp.304-309
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    • 2006
  • Background: Interstitial pneumonia is associated with an increased risk of lung cancer but the outcome of surgical resection in this setting is unknown. The purpose of this study was to determine the relationship between pre-operative interstitial pneumonia (IP) and post-operative respiratory failure. Material and Method: A retrospective review of 672 patients with lung cancer who underwent curative pulmonary resection at the Hospital of Catholic University Medical College between 1997 and 2005 was undertaken. The patients were divided into two groups according to preexisting interstitial pneumonia and not by the pre-operative chest HRCT or findings of pathologic papers. The pre-operative data and cancer-related findings were analyzed between the IP group and non-IP group, and between the respiratory failure group and non-failure group in IP patients. Result: Twenty-eight patients (4.2%) of the developed post-operative respiratory failure and this proved to be fatal in 21 of these patients. We could find preoperative interstitial pathology in 53 patients (7.9%) among the 672 patients. The incidences of respiratory failure were 11.3% (6/53 cases) and 3.6% (22/619 cases) in IP group and non-IP group respectively, Conclusion: Interstitial pneumonia was considered one of the risk factors for developing postoperative acute respiratory failure in patients with lung cancer.

A Review on Treatment of Essential Tremor in Traditional Chinese Medicine (본태성 진전에 대한 중의학 연구동향)

  • Shin, A-Ri;Bae, Yeong-Long;Lim, Jae-Yu;Lee, Seung-Hwan;Kim, Sang-Ho;Lim, Jung-Hwa
    • Journal of Oriental Neuropsychiatry
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    • v.28 no.2
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    • pp.95-107
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    • 2017
  • Objectives: This study was performed to review studies on Essential Tremor (ET) in Traditional Chinese medicine (TCM). Methods: We reviewed papers in the China National Knowledge Infrastructure (CNKI) from 2007~2016. Search keywords were 原发性震颤, 特发性震颤, essential tremor and idiopathic tremor, and excluded non-clinical studies, non-related to ET or TCM studies, theses for degrees and non-Randomized Controlled Trial (RCT). The quality of the articles was assessed by Jadad scale and the Risk of Bias (RoB). Results: Thirteen studies were selected. 'Criteria for the diagnosis of ET' was most frequently used as diagnostic criteria. 'Tremor rating scale' was primarily used for outcome measurement. Meta-analysis of nine trials revealed the effective rate of acupuncture and Western medicine (WM+Acu) groups was significantly higher compared to the WM group (RR: 1.48, 95 percent CI: 1.20 to 1.82, p=0.0002, $I^2=0$ percent) and tremor rating scale was also significantly decreased in the treatment group (MD: -1.35, 95 percent CI: -2.17 to -0.54, p=0.001, $I^2=0$ percent). Also, effective rates of Electro-acupuncture (EA) and Chinese herbal medicine (CHM) groups were significantly higher than that of the WM group {(RR: 1.53, 95 percent CI: 1.22 to 1.92, p=0.0003, $I^2=0$ percent) in EA vs. WM and (RR: 1.35, 95 percent CI: 1.16 to 1.57, p<0.0001, $I^2=0$ percent) in CHM vs. WM}. However, the quality of selected clinical studies was poor. Conclusions: Treatment of ET in TCM may be more effective and safe than in Western medicine. Therefore, we hope this study will lead to further clinical research on treatment of ET in Korean medicine.

An analysis of Chinese Policy for Establishing the World Class University and the characteristics of 'Double First Class University Plan' (중국의 세계일류대학 육성정책의 성과 및 '쌍일류' 건설의 주요 내용과 특징 분석)

  • Lee, Su-Jin
    • Korean Journal of Comparative Education
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    • v.28 no.4
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    • pp.107-135
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    • 2018
  • This study examines the contents and characteristics of 'Double First Class University Plan', which is conceived by Chinese government in 2015, following the current 211, 985 projects to develop comprehensively a group of elite Chinese universities and individual university departments into world class universities and disciplines by the end of 2050. For this study, we used the literature analysis method and collected various policy documents, research papers, newspapers and books published in China regarding this plan. First, this study looks at the development process, performance and limitations of 211, 985 projects. Second, it defines the concept of the world class university mentioned in China, and looks at the objectives and highlights of the plan. Finally, this study summarizes the characteristics of 'Double First Class University Plan' and the results such as focusing on the university's tradition and characteristic, cultivation and attraction of human resources, intensive financial support, and the introduction of a competitive system. Based on the results, this study proposes several implications such as establishing and implementing long-term and comprehensive higher education policies, inducing local government participation and support, focusing on fostering talents and developing disciplines, and putting emphasis on Korean characteristics in developing world class universities.

Understanding and Prevention of Fall-related Injuries in Older Adults in South Korea: A Systematic Review (한국 노인의 넘어짐과 연계된 인체손상에 대한 이해와 예방: 체계적 문헌 고찰)

  • Lim, Ki-taek;Lee, Ji-eun;Park, Ha-eun;Park, Su-young;Choi, Woochol Joseph
    • Physical Therapy Korea
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    • v.26 no.2
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    • pp.34-48
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    • 2019
  • Background: Fall-related injuries in older adults are a major health problem, and the risks and mechanisms of these injuries should be affected by race, culture, living environment, and/or economic status. Objects: Research articles have been systematically reviewed to understand fall-related injuries in older adults in South Korea. Methods: 128 published research papers have been found through the Korea Citation Index and the Korean Studies Information Service System, and reviewed in various perspectives, including incidents, fall death rates, medical costs, causes, injury sites and types, locations where falls occurred, prevention strategies, scholarly fields interested in fall injuries, and the role of physical therapy. Results: Fall-related injuries were found to be more common in women than in men, and the number of incidents increased with age, with the highest rate found in individuals over 85 years old. Risk of fall injury was associated with education level, comorbidities, and fear of falling. Common places where falls occurred included the bathroom, living room, stairs, and hallway. Common types of injury included bruises, fractures, and sprains in the lower extremities. Intervention strategies included exercise programs, education, and protective clothing. Scholarly fields interested in fall-related injuries in older adults included medicine, nursing, physical therapy, occupational therapy, physical education, pharmacology, oriental medicine, biomedical engineering, design, clothing, and textiles. Physical therapy intervention using proprioceptive neuromuscular facilitation has been used to improve one's balance. Conclusion: Any movement during the activities of daily living can lead to a fall. Physical therapists are highly educated to analyze human movements and should be involved in more research and practices to solve fall-related injuries in older adults.

Convergence Effects of Proprioceptive Neuromuscular Facilitation on Dynamic Balance in Chronic Stroke : A Meta-Analysis (고유수용성신경근촉진법이 만성 뇌졸중 환자의 동적 균형에 미치는 융복합적 효과: 메타분석)

  • Park, Se-Ju;Lee, So-In;Jung, Ho-Jin
    • Journal of the Korea Convergence Society
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    • v.12 no.4
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    • pp.275-284
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    • 2021
  • The study attempted to systematically and comprehensively analyze individual studies in which proprioceptive neuromuscular facilitation (PNF) was performed with chronic stroke patients. Selection criteria included type of participants (stroke patients), intervention (PNF), comparison (intervention group or non-intervention group), outcomes (effect on dynamic balance), and study design (randomized controlled trial). We searched seven literature databases, and selected 17 papers that met our selection criteria. For meta-analysis, effect size of each individual study was extracted using the R project for Statistical computing version 4.0.3. Rob 2.0 tool, developed by the Cochrane group, was used to evaluate the quality of each individual study. The overall effect size PNF with dynamic balance was 0.59 (95% CI=0.41-1.77), which was significantly different than the median effect size (p<0.05). The sub-group for dynamic balance was analyzed, for effect sizes of BBS (0.50), TUG (0.78), and FRT (0.51). Thus, PNF intervention has a positive impact on improve of dynamic balance by chronic stroke patients.