• Title/Summary/Keyword: Medical college

Search Result 30,787, Processing Time 0.053 seconds

Endothelial Aquaporin-1 (AQP1) Expression Is Regulated by Transcription Factor Mef2c

  • Jiang, Yong;Liu, He;Liu, Wen-jing;Tong, Hai-bin;Chen, Chang-jun;Lin, Fu-gui;Zhuo, Yan-hang;Qian, Xiao-zhen;Wang, Zeng-bin;Wang, Yu;Zhang, Peng;Jia, Hong-liang
    • Molecules and Cells
    • /
    • v.39 no.4
    • /
    • pp.292-298
    • /
    • 2016

  • Aquaporin 1 (AQP1) is expressed in most microvasculature endothelial cells and forms water channels that play major roles in a variety of physiologic processes. This study aimed to delineate the transcriptional regulation of AQP1 by Mef2c in endothelial cells. Mef2c cooperated with Sp1 to activate human AQP1 transcription by binding to its proximal promoter in human umbilical cord vein endothelial cells (HUVEC). Over-expression of Mef2c, Sp1, or Mef2c/Sp1 increased HUVEC migration and tube-forming ability, which can be abolished AQP1 knockdown. These data indicate that AQP1 is a direct target of Mef2c in regulating angiogenesis and vasculogenesis of endothelial cells.

  • https://doi.org/10.14348/molcells.2016.2223 인용 PDF KSCI

Does colonic dilation infer the colonic diseases?

  • Cheon, Haeng-Bok;Cho, Hang-Myo;Kim, Ju-Hyung;Chun, Hae-Young;Baik, Chul;Yun, Seok-Ju;Kim, Min-Hyuk;Kim, Gon-Hyoung;Chang, Dong-Woo
    • Proceedings of the Korean Society of Veterinary Clinics Conference
    • /
    • 2008.05a
    • /
    • pp.116-116
    • /
    • 2008

  • PDF

The First Living-Donor Lobar Lung Transplantation in Korea: a Case Report

  • Choi, Sehoon;Park, Seung-Il;Lee, Geun Dong;Kim, Hyeong Ryul;Kim, Dong Kwan;Jung, Sung-Ho;Yun, Tae-Jin;Kim, In Ok;Choi, Dae-Kee;Choi, In-Cheol;Song, Jong-Min;Hong, Sang-Bum;Shim, Tae Sun;Jo, Kyung-Wook;Lee, Sang-Oh;Do, Kyung-Hyun;Chae, Eun Jin
    • Journal of Korean Medical Science
    • /
    • v.33 no.43
    • /
    • pp.282.1-282.6
    • /
    • 2018

  • Lung transplantation is the only treatment for end-stage lung disease, but the problem of donor shortage is unresolved issue. Herein, we report the first case of living-donor lobar lung transplantation (LDLLT) in Korea. A 19-year-old woman patient with idiopathic pulmonary artery hypertension received her father's right lower lobe and her mother's left lower lobe after pneumonectomy of both lungs in 2017. The patient has recovered well and is enjoying normal social activity. We think that LDLLT could be an alternative approach to deceased donor lung transplantation to overcome the shortage of lung donors.

  • https://doi.org/10.3346/jkms.2018.33.e282 인용 KSCI