• Journal of Life Science
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• v.32 no.7
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• pp.523-531
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• 2022

The purpose of this study was to evaluate the effect of antioxidant and anti-adipogenic activities in ethanol extracts from herb mixture (Ephedra sinica, Atractylodes lance, Gypsum fibrosum, and Theobroma cacao). DPPH, ABTS⁺ radical and xanthine oxidase scavenging activities were measured for antioxidant activity. Extracts of the herb mixture had 75.0, 100.8, and 79.5% scavenging activities at 1,000 ㎍/ml concentration, respectively. We investigated the inhibition of adipogenesis and adipocyte differentiation with an extract of an herb mixture in 3T3-L1 preadipocytes. An extract from the herb mixture at concentrations between 0 and 50 ㎍/ml did not affect 3T3-L1 cell viability. Treatment with herb mixture extracts of 25, 50, and 75 ㎍/ml in 3T3-L1 preadipocytes inhibited lipid accumulation in a dose-dependent manner. As a result of a Western blot experiment, it was shown that the herb mixture inhibited the differentiation transcription factors, PPARγ and C/EBPa, by 44.2 and 77.6%, respectively, at a concentration of 75 ㎍/ml in MDI-induced differentiated 3T3-L1 cells. As a result of RT-PCR, the gene expression of C/EBPa, SREBP-1c, and PPARγ was significantly inhibited by 43.4%, 59.6%, and 55.3%, respectively, at the concentration of 75 ㎍/ml of the herb mixture compared with the MDI-treated group. In addition, the expression of fatty acid synthase (FAS), a fatty acid synthesis regulator, was suppressed. These results can be applied to develop a functional food for anti-obesity with a herb mixture.

• Journal of Industrial Convergence
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• v.20 no.5
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• pp.93-100
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• 2022

This study is a descriptive survey study that applies the planned behavior theory to identify the factors influencing the childbirth intention of unmarried men and women. Data were collected from April 05 to April 23, 2021 for 168 unmarried men and women. As a result of the study, in general characteristics, male, old, highly educated, occupational, and non-regular workers had statistically significantly higher childbirth intentions. As a result of examining the correlation between the variables constituting the theory of planned behavior(TPB), it was found that the more positive the attitude toward childbirth, the greater the subjective norm, and the greater the perceived behavior control, the higher the intention to give birth. Multiple regression analyses showed that the factors affecting fertility intention on men and women. The factors affecting fertility intention in men was attitude, with an explanatory power of 62.2% and the factors affecting fertility intention in women were attitudes and perceived behavioral control, and the explanatory power of these variables on fertility intention was 69.0%. In order to increase the intention to give birth, a comprehensive approach is needed, and the research is meaningful in that the results of this study provided basic data in the development of policies and education programs related to low birth rates in the future.

• Journal of the Korean Society of Radiology
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• v.16 no.5
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• pp.553-558
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• 2022

The purpose of this work was a simulation study to evaluate the virtual monochromatic (VM) image quality of blood vessels compared to the monochromatic image. Dual-energy images were obtained based on the linear attenuation coefficients of five materials at 50 keV and 80 keV at low- and high-energies, respectively. A weighting factor is required to synthesize the VM image, and the liver and bone were used as basis materials to obtain the weighting factor. VM images were synthesized at energies ranging from 30 keV to 100 keV. Image quality was evaluated by Contrast to noise ratio (CNR) and noise by setting calcium and contrast medium as signals and blood as background. According to the results, the energies with the maximum CNR were 50 keV and 60 keV for calcium and contrast medium, respectively. The energies showing the minimum noise were 70 keV, 70 keV, and 60 keV in calcium, iodine contrast medium, and blood, respectively. The VM image can contribute to the improvement of diagnostic performance in CT examination because it can implement an image at the optimal energy that minimize noise and maximize CNR.

• Journal of the Korean Association of Geographic Information Studies
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• v.25 no.1
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• pp.77-100
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• 2022

In the era of low growth, many provincial cities are experiencing population decline and aging. Population decline phenomena such as reduction of productive manpower, reduction of finances, deterioration of quality of life, and collapse of the community base are occurring in a chain and are being pushed to the brink of extinction of the cities. This study aims to propose a methodology to objectively estimate the employment creation centers and setting the basic unit of industrial-centered zoning by applying spatial statistical techniques and GIS for the application of the compact city plan as an efficient spatial management policy in a city with a declining population. In details, based on reviewing previous studies on compact city, 'employment complex index(ECI)' were defined considering the number of workers, the number of settlers, and the area of development land, the employment creation center was estimated by applying the 'Local Moran's I' and 'Getis-Ord's Hot-Spot Analysis'. As a case study, changes in the four years of 2013, 2015, 2017, and 2019 were compared and analyzed for Changwon City. As a result, it was confirmed that the employment creation center is becoming compacted and polycentric, which is a significant result that reflects the actual situation well. This results provide the basic data for functional and institutional territorial governance for the regional revitalization platform, and provide meaningful information necessary for spatial policy decision-making, such as population reduction, regional gross domestic product, and public facility arrangement that can respond to energy savings, transportation plans, and medical and health plans.

• Journal of the Korean Society of Radiology
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• v.17 no.1
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• pp.53-62
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• 2023

The purpose of this study is to find an optimized imaging technique and evaluate its usefulness by comparing and analyzing the difference in contrast enhancement of lower extremity artery according to the patient's heart rate during lower extremity Computed Tomography Angiography examination. From January 2022 to August 22nd, 139 outpatients who visited Ajou University Hospital and underwent lower extremity angio CT examination were targeted. According to the heart rate, the groups were divided into four groups: A(HR ≤65), B(65 < HR < 80), C(80≤ HR). In addition, among patients with a heart rate of 65 or less, the heart rate was considered, and the scan was divided into D, E, F group with a delay time. The time of arrival of contrast medium and the average value of contrast enhancement were compared and analyzed. As a result of quantitative evaluation, B and C groups with a heart rate of more than 65 times had better HU values in the popliteal artery than A group (HR ≤ 65), and D group showed better HU improvement effects compared to A group (p<0.001). The comparative analysis with other groups was insignificant. The difference in heart rate affected the angiographic intensity of the lower extremities artery. Therefore, it is effective to apply the appropriate test timing for each patient by using the heart rate during the lower extremity angio CT Scan.

• Therapeutic Science for Rehabilitation
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• v.11 no.3
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• pp.37-50
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• 2022

Objective : This study aimed to investigate the use of electromyography (EMG) to evaluate upper limb movement or function in stroke patients. Methods : We reviewed papers published in journals between January 2018 and December 2021 using PubMed, EMBASE, Scopus, RISS, and KISS. The main keywords of databases were ('stroke' OR 'hemiplegia') AND ('EMG' OR 'electromyography' OR 'electromyogram' OR 'muscle activity') AND ('Upper limb' OR 'Hand'). Results : Fifteen studies were selected, most of which evaluated muscle activity. Interventions performing tasks related to activities of daily living (ADLs), using assistive technology, and interventions that provide repetitive training were most frequently applied. Conclusions : When evaluating upper limb functions using electromyography, it is meaningful to present an evaluation that can be used according to the purpose of the study and to provide a basis for setting up interventions that can utilize electromyography during evaluation.

• The Journal of the Convergence on Culture Technology
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• v.8 no.3
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• pp.15-23
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• 2022

This study is a non-equivalent control group quasi-experimental design to test the effectiveness of educational programs on human tissue donation for nursing students to change the perception of human tissue donation. The subjects of the study were 75 nursing students located in U city, 38 in the experimental group and 37 in the control group. The data were analyzed using SPSS/WIN 23.0. The average age was 22.39±0.75 years old, women 84.2% and there was no difference in general characteristics and prior data between the two groups. Knowledge (F=-8.921, p<).001, Attitude (F=-5.414, p<).001, perception of death (F=-3.075, p=).004) showed a significant difference, and the educational intervention of nursing students developed to promote human tissue donation showed a positive effect on human tissue donation. When programs to be applied to educational institutions that train not only medical personnel but also experts in other fields must be developed, the establishment and stability of the human tissue donation culture will be solidified. It is also suggested that health care campaigns and education in public educational institutions should be conducted together.

• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.107-119
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• 2022

This study was a descriptive research study to identify the effects of related knowledge to COVID-19, infection control performance, and job stress in emergency department nurses due to COVID-19 on nursing performance, to improve emergency department nurses' ability to cope with emerging infectious diseases and to prepare basic data for effective nursing work. This study was collected data from August, 10 until September, 10, 2021, for 165 emergency department nurses in 26 hospitals, which were located in G province and designated as regional emergency medical institutions, and total 150 copies were finally analyzed. Data were analyzed using descriptive statistics, t-test, ANOVA, correlation, and multiple regression. As a result of analyzing the variables affecting the subject's nursing job performance by multiple regression using the hierarchical selection method, the higher the infection control performance and the higher the job stress, the more higher the nursing job performance, and the explanatory power was 18.4%. The study results showed that infection control performance, job stress, and non-shift work had an effect on nursing performance. It was thought that various plans to protect them, reduced tasks to efficiently perform and the nursing ability to cope with emerging infectious disease should be prepared to improve and reduce the job stress of emergency department nurses.

• Journal of Service Research and Studies
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• v.13 no.1
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• pp.76-95
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• 2023

As information and communications technology-based "smart hospitals" and "digital healthcare" have become a hot topic in the healthcare field, hospital mobile apps are gaining attention; but, the utilization rate is low due to lack of publicity, unstable systems, and late updates. In this situation, systematic research is needed to increase the utilization rate of hospital mobile apps, but related research has been rare. Therefore, this study integrates the information systems success model (ISSM) from the technical perspective and the expectation-confirmation model (ECM) from the cognitive perspective to demonstrate the influence mechanism on the continuous use intention of hospital mobile apps. For this purpose, an online survey was conducted among 181 Korean adults who have used hospital mobile apps. The results of the structual equation modeling showed that most of the quality factors have significant effects on expectation confirmation, perceived usefulness, and satisfaction. Additionally, expectation confirmation significantly affects perceived usefulness and satisfaction, and both perceived usefulness and satisfaction significantly affect the continuous use intention of hospital mobile apps. This study is of importance in that it integrates the ISSM and ECM and applies them to the context of using hospital mobile apps, which are underutilized in the healthcare field, and provides practical implications for increasing the utilization rate of hospital mobile apps and operating effective and efficient services through the findings.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.355-363
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• 2023

The purpose of this study was attempted to confirm the relationship between medical workers' knowledge of the elderly, burn out, job satisfaction and awareness of elder abuse. The study was conducted on 371 doctors, nurses, and nurse's aides working at eight health centers, 15 nursing hospitals, and 30 university hospital institutions. Looking at the relationships between variables, this study found that knowledge of the elderly was a significant positive correlation with awareness of elder abuse(r=.14, p<.01), and burn out was a significant negetive correlation with job satisfaction(r=-.55, p<.01) and awareness of elder abuse(r=-.10, p<.05). Job satisfaction was a significant positive correlation with awareness of elder abuse(r=.13, p<.01). Awareness of elder abuse was a significant positive correlation with knowledge of the elderly(r=.14, p<.01) and was a significant negetive correlation with burn out(r=-.10, p<.05). As a result of this study, it is expected that Hospital workers can have a positive perception and attitude toward the elderly by reducing their burnout and improving their job satisfaction.