• Title/Summary/Keyword: Medical Engineering

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Gangjihwan Reduces Body Weight Gain in a ob/ob Female Mice (Ob/Ob 비만마우스 모델에서 강지환(降脂丸)의 체중감량 효과)

  • Baek, Song Young;Lee, Hye Rim;Park, Ju Hye;Yoon, Michung;Yoon, Yoosik;Yang, Heejung;Choi, Yung Hyun;Shin, Soon Shik
    • Herbal Formula Science
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    • v.25 no.2
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    • pp.193-207
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    • 2017
  • Objectives : This study was designed to investigate anti-obesity effects of DF in a ob/ob mouse model. Methods : Fifteen-week-old ob/ob mice were divided into four groups: a normal lean group given a standard diet, an ob/ob control group given a standard diet, and DF(1) and DF(2) groups given a standard diet with DF(1) (300 mg/kg), and DF(2) (600 mg/kg), respectively. After 10 weeks of treatment, body weight gain, feeding efficiency ratio, blood lipid markers, fat weight and histology were examined. Results : Body weight gain and fat mass were significantly decreased in DF(1) and DF(2) groups compared with control. The extent of decreases was eminent in DF(2) group. Feeding efficiency ratio were significantly decreased in DF(2) group compared with control. Consistent with their effects on body weight gain and fat mass, circulating concentrations of LDL, total cholesterol, free fatty acid, and insulin were decreased in DF(2) group compared with control. The size of adipocytes were significantly decreased by DF(2) compared with control. Consistent with their effects on body weight gain, hepatic lipid accumulation and liver weights were reduced in DF compared with control. Conclusions : In conclusion, these results suggest that DF not only decrease feeding efficiency ratio, and blood anti-obesity biomarkers, but also reduce fat mass, contributing to the improvement of obesity. DF also inhibits hepatic lipid accumulation.

The Influence of the Front Surface Power and the Refraction Index on RMS Spot Diameter (전면 굴절력과 굴절률이 착락원의 크기에 미치는 영향)

  • Park, Seong-Jong;Shin, Cheol-Guen;Ju, Seok-Hee
    • Journal of Korean Ophthalmic Optics Society
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    • v.8 no.2
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    • pp.57-63
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    • 2003
  • To investigate the RMS SD(Root Mean Square Spot Diameter) in a back focal plane as the front surface power, the center thickness, and the refraction index vary, we use programs which are Cove V and LOSA 2.0, and consider a spectacle lens with back vertex power of -4.00D and diameter of 70 mm. We also consider the front surface power varied from 0.00 to 10.00D, the center thickness varied from 1.1 to 2.0 mm, and the indices which are $n_d$ = 1.498, 1.523, 1.586, and 1.660, respectively. As the front surface power increases the RMS SD in the back focal plane increase rapidly. When the refraction index increases, the RMS SD in the back focal plane decrease and the variation of RMS SD in the back focal plane decreases as the front surface power increases. When the center thickness of spectacle lens increases, the RMS SD in the back focal plane is constant and the edge thickness of that increases. We know from these results that the image in the back focal plane of a spherical spectacle lens improves as the front surface power increases and the refraction index decreases.

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Effect of Multifaceted Intervention Program on Multi-Dimensional Psychologic Condition, Empowerment, Work Readiness, and Functional Capacity in Industrially Injured Workers (다면재활프로그램이 산업재해근로자의 다차원 심리상태, 역량강화, 직업복귀준비 및 작업능력에 미치는 효과)

  • Noh, Dong-hee;Song, Moon-Hee;Jo, Eun-Ju;Kang, Seong-Gu;Kim, Kyoung-Hwa;Kam, Kyung-Yoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.2
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    • pp.293-301
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    • 2018
  • This study examined the effects of a multifaceted intervention program on the psychological condition, empowerment, work readiness, and functional capacity for job performance of industrially injured workers. Twelve injured workers in C hospital were included in this study. The subjects participated in a social rehabilitation program 2 hours a day, twice a week, for 8 weeks in total, as well as a work hardening program 3 to 4 hours a day, 5 times a week, for 8 weeks in total. The study was conducted from March to September, 2017. A multi-dimensional psychological examination, empowerment scale, work readiness interview and functional capacity evaluation were conducted and the test scores compared before and after the program with the Wilcoxon signed rank test. In the multi-dimensional psychological examination, there were significant differences in the levels of anxiety, depression, lack of social support, and somatization symptoms (p<.05) except anger. The participants also showed significant differences in the empowerment scale, work readiness scale, and functional capacity evaluation. This study suggests that a multifaceted intervention program can be effective in improving the psychologic condition, empowerment, work readiness, and functional capacity of industrially injured workers and, in turn, may improve their rate of returning to work.

Vertical Growth of Amorphous SiOx Nano-Pillars by Pt Catalyst Films (Pt 촉매 박막을 이용한 비정질 SiOx 나노기둥의 수직성장)

  • Lee, Jee-Eon;Kim, Ki-Chul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.1
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    • pp.699-704
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    • 2018
  • One-dimensional nanostructures have attracted increasing attention because of their unique electronic, optical, optoelectrical, and electrochemical properties on account of their large surface-to-volume ratio and quantum confinement effect. Vertically grown nanowires have a large surface-to-volume ratio. The vapor-liquid-solid (VLS) process has attracted considerable attention for its self-alignment capability during the growth of nanostructures. In this study, vertically aligned silicon oxide nano-pillars were grown on Si\$SiO_2$(300 nm)\Pt substrates using two-zone thermal chemical vapor deposition system via the VLS process. The morphology and crystallographic properties of the grown silicon oxide nano-pillars were investigated by field emission scanning electron microscopy and transmission electron microscopy. The diameter and length of the grown silicon oxide nano-pillars were found to be dependent on the catalyst films. The body of the silicon oxide nano-pillars exhibited an amorphous phase, which is consisted with Si and O. The head of the silicon oxide nano-pillars was a crystalline phase, which is consisted with Si, O, Pt, and Ti. The vertical alignment of the silicon oxide nano-pillars was attributed to the preferred crystalline orientation of the catalyst Pt/Ti alloy. The vertically aligned silicon oxide nano-pillars are expected to be applied as a functional nano-material.

Evaluation and Experimental Production of Single-Phase Full-wave Rectification Type for X-ray Equipment of High Precision (고정밀도의 단상전파정류형 X선 장치의 제작 및 평가)

  • Han, Dong-Kyoon;Jung, Jae-Eun;Choi, Jun-Gu;Seoun, Youl-Hun;Ko, Shin-Gwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.1
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    • pp.413-419
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    • 2011
  • Diagnosis X-ray equipment localized at 1950's but it is developed suddenly at 1960's with demand together. Manufacture of Diagnostic X-ray equipment is controled by the KS regulation and the Ministry of Health and Welfare because of hazardous element etc. exposure by radiation. Most of diagnostic X-ray equipment ware single phase and three phase full-wave rectification but from 1980's it transforms it was exchanged in inverter type X-ray equipment. Inverter type X-ray equipment produces approximately 50~80% more average photon intensity then single phase full-wave rectification and the accuracy is high. But from a clinic it dose not use because expensive therefor the efficiency improvement of single phase full-wave rectification is necessary. We produced single phase full-wave rectification X-ray equipment control unit, high tension transformer, filament heating transformer, rectification circuit, high tension cable and others and evaluated efficiency, in result which is excellent compare with Rule of Safety Management and KS regulation.

High Time-resolution Characterization of PM2.5 Sulfate Measured in a Japanese Urban Site

  • Ma, Chang-Jin;Kang, Gong-Unn;Kim, Ki-Hyun
    • Asian Journal of Atmospheric Environment
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    • v.9 no.4
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    • pp.280-287
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    • 2015
  • The high time-resolution monitoring data are essential to estimate rapid changes in chemical compositions, concentrations, formation mechanisms, and likely sources of atmospheric particulate matter (PM). In this study, $PM_{2.5}$ sulfate, $PM_{2.5}$, $PM_{10}$, and the number concentration of size-resolved PMs were monitored in Fukuoka, Japan by good time-resolved methods during the springtime. The highest monthly average $PM_{2.5}$ sulfate was found in May ($8.85{\mu}g\;m^{-3}$), followed by April ($8.36{\mu}g\;m^{-3}$), March ($8.13{\mu}g\;m^{-3}$), and June ($7.22{\mu}g\;m^{-3}$). The cases exceed the Japanese central government's safety standard for $PM_{2.5}$ ($35{\mu}g\;m^{-3}$) reached 10.11% during four months campaign. The fraction of $PM_{2.5}$ sulfate to $PM_{2.5}$ varied from 12.05% to 68.11% with average value of 35.49% throughout the entire period of monitoring. This high proportion of sulfate in $PM_{2.5}$ is an obvious characteristic of the ambient $PM_{2.5}$ in Fukuoka during the springtime. However, the average fraction of $PM_{2.5}$ sulfate to $PM_{2.5}$ in three rain events occurred during our intensive campaign fell right down to 15.53%. Unusually high $PM_{2.5}$ sulfate (> $30{\mu}g\;m^{-3}$) marked on three days were probably affected by the air parcels coming from the Chinese continent, the natural sulfur in the remote marine atmosphere, and a large number of ships sailing on the nearby sea. The theoretical number concentration of $(NH_4)_2SO_4$ in $PM_{0.5-0.3}$ was originally calculated and then compared to $PM_{2.5}$ sulfate. A close resemblance between the diurnal variations of the theoretically calculated number concentration of $(NH_4)_2SO_4$ in $PM_{0.5-0.3}$ and $PM_{2.5}$ sulfate concentration indicates that the secondary formed $(NH_4)_2SO_4$ was the primary form of sulfate in $PM_{2.5}$ during our monitoring period.

Korean Customer Attitudes Towards SNS Shopping

  • Cho, Young-Sang;Heo, Jeong-Yoon;Youn, Myoung-Kil
    • Journal of Distribution Science
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    • v.10 no.8
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    • pp.7-14
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    • 2012
  • As a new format of retailing, social shopping on SNS has rapidly grown in recent. Although there is much literature associated with customer behaviours in the academic world, little attention has been paid to identifying the shopping patterns of SNS shoppers. This paper will, thus, identify how perceived value has an impact on the buying intention of SNS shoppers, after illustrating what kind of factor influences the formation process of perceived value in the Korean marketplace. Given that SNS shoppers are for the most part 20s as well as 30s, the authors handed out questionnaires to them. Furthermore, based on literature review results, the conceptualised research model was developed. Despite lack of literature, the authors developed five constructs like price reduction, quantity- and time-limited message, product ranges, information-sharing, and required number of shoppers. The researchers made a considerable effort to identify the relationship between research concepts and each variable, based on a few research analysis methods such as frequency analysis, the Varimax rotation technique used orthogonal rotation, Cronbach's Alpha, PCA (Principle Component Analysis), and the like. Amongst the 5 variables used to measure the degree of influences on the perceived value as a social shopping characteristic, it has been evident that price cut, required minimum shoppers, product variety, and information-sharing have a positive impact on the perceived value formation processes of SNS customers. Also, this research implies that SNS retailers can differentiate themselves from other retailers by differently using the above factors. From a practitioner's point of view, these factors should be strategically used to increase the social shopping opportunities of SNS users. It is, furthermore, evident that the perceived value formed by the above 4 factors have played an important role in the buying decision process of SNS customers. In a sense, whether customers are aware of higher price cut rates, information-sharing, required minimum shoppers, and product variety has a positive impact on making buying decisions. From a retailer's point of view, online shopping mall operators are able to use blog as well as twitter to improve the buying intention as a marketing tool of social network, because the business activities provided by social shopping retailers, like the rapid, accurate responses to customer requirements, the provision of a variety of information, and the communications between customers are closely related to buying intentions. There are a few research limitations to conduct this empirical research. It was not easy to review prior papers, due to its lack. In spite of the increasing number of SNS shoppers in Korea, little research attention has been paid to this kind of research topic by academicians, because buying products or services through SNS is in its infancy. With regard to research populations, it would be difficult to generalise the research findings in Korea, owing to unbalanced respondent distribution. Considering the above research limitations as well as the growth of social shopping, many authors should pay considerable attention to SNS-related issues in the future, and develop the more sophisticated criteria to measure the characteristics of SNS shoppers.

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Metabolic Changes in Pericontusional Edematous Areas in Mild Head Injury Evaluated by Proton MRS (경도 두부외상 환자에서 뇌좌상주위 부종영역에서의 자기공명분광법을 이용한 대사변화)

  • Hong, Sang-Su;Son, Byung-Chul;Cho, Byung Gil;Kim, Euy-Nyeng;Kim, Bum-Soo;Park, Chun-Kum;Choe, Bo-Young;Kim, Moon-Chan;Kang, Joon-Ki
    • Journal of Korean Neurosurgical Society
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    • v.29 no.9
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    • pp.1233-1237
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    • 2000
  • Objectives : In order to evaluate the metabolic changes associated with pericontusional edematous area in mild head injury, proton magnetic resonance spectroscopy(1H-MRS) was performed in mild head injury patients (initial GCS score 13-15) with focal brain contusion. Methods : Seven head injury patients with initial GCS 13-15(3 males and 4 females : age range 15-65 years, mean age 33 years) have underwent 1H-MRS evaluations. The patients were examined within 7 days after injury(n=7) and 2 months after injury(n=5). The region of interest(ROI) was selected in the edematous area adjacent to traumatic brain contusion upon T2-weighted MR images and a corresponding region of the contralateral hemisphere (ROC, region of contralateral corresponding hemisphere) was examined as well. The metabolic ratios of NAA/Cr and lactate/Cr were compared between ROIs, ROCs and control values. Results : In initial NAA/Cr ratios, the values of ROIs were significantly lower than those of the controls(p=0.009), but there was no difference either between ROIs and ROCs(p=0.410) or between ROCs of patients and the control (p=0.199). In lactate/Cr ratios, the ROIs in all seven patients and the ROCs in two showed increased lactate signals. The lactate/Cr ratios of the ROIs were significantly elevated as compared to those of the ROCs(p=0.02) and the control(p=0.015). In two months follow-up, lactate signals were absent or significantly reduced(p=0.015). In no patients, clinical or radiological deterioration has been observed. Conclusion : Our 1H-MRS results demonstrate that there are significant ischemic changes in pericontusional edematous areas as indicated by elevated lactate signals in the patients with mild head injury. But there were no consistent neural loss or dysfunction in these area. There findings suggest that pericontusional edematous areas can be vulnerable to secondary brain insults even in the patients with mild head injury.

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An Efficient BC Approach to Compute Fractal Dimension of Coastlines (개선된 BC법과 해안선의 프랙탈 차원 계산)

  • So, Hye-Rim;So, Gun-Baek;Jin, Gang-Gyoo
    • Journal of Navigation and Port Research
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    • v.40 no.4
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    • pp.207-212
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    • 2016
  • The box-counting(BC) method is one of the most commonly used methods for fractal dimension calculation of binary images in the fields of Engineering, Science, Medical Science, Geology, etc due to its simplicity and reliability. It deals with only square images with each size equal to the power of 2 to prevent it from discarding unused pixels for images of arbitrary size. In this paper, we presents a more efficient BC method based on the original one, which is applicable to images of arbitrary size. The proposed approach allows the number of the counting boxes to be real to improve the estimation accuracy. The mean absolute error performance is computed on two deterministic fractal images whose theoretical dimensions are well known to compare with those of the existing BC method and triangular BC method. The experimental results show that the proposed method can outperform the two methods and assess the complexity of coastline images of Korea and Chodo island taken from the Google map.

Induction of Demyelination of Neuronal cells by Sindbis Virus (Sindbis Virus에 의한 뉴런세포의 탈수초의 유도)

  • Sa, Young-Hee;Kim, Hyun Joo;Kweon, Tae Dong;Kim, Ji-Young;Lee, Bae Hwan;Hong, Seong-Karp
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.05a
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    • pp.584-587
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    • 2018
  • Many viruses including mouse hepatitis virus, corona, measles, and sidbis viruses are known as causative virus of inducing demyelination which means destruction of myelination in nervous system of mice. The purpose of this study is to investigate processing of myelination by co-culture of Schwann cells and neuronal cells and demyelination induced by infection of sindbis virusin rat. Schwann cells and neuronal cells from dorsal root ganglion (DRG) in embryos (E16) of rat were cultured in vitro respectively. The purified neuronal cells with anti-mitotic agents and purified Schwann cells were co-cultured. After that, infection of sindbis virus into this myelinated co-culture system was performed. Myelination and demyelination process were observed using antibody of myelin basic protein meaning presence of myelination.We identified myelination and demyelination processing using antibody of peripheral myelin protein 22 (PMP 22) meaning presence of myelinated neuron. This study was supported by the Basic Research Program through the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2015R1C1A1A01053484 and 2017R1A2B3005753).

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