• Title, Summary, Keyword: Medical Engineering

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A Study on Breakdown Patterns which influence Down-Time of Medical Equipment (의료기기의 Down-Time에 영향을 미치는 고장유형에 관한 연구)

  • Seo, G.H.;Han, K.D.;Kim, H.K.;Lee, H.S.;Lim, H.S.;Kwon, H.N.
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.100-101
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    • 1998
  • In this paper, we've studied on the Breakdownpatterns which hove an effect on Down-Time of Medical Equipment. This study is based on the statistics of MMS(Maintenance Management System) accumulated since the opening of Samsung Medical Center. We hope that this paper, which is acquired through the analysis about the seasonal feature, the work pattern feature and the period used, is useful to reduce a term of Down-Time and to retrench hospital management cost.

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HOW TO COMPOSE AND UTILIZE COMPARISION CHART OF MEDICAL EQUIPMENT FOR PURCHASING (의료기기 구입을 위한 의료기기(醫療機器)비교표 작성방법 및 활용방안)

  • Kim, Won-Kyou;Kang, Hee-Suk;Park, Min-Su;Kim, Tae-Jong;Kwon, Hyuk-Nam
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.108-109
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    • 1998
  • As the need of enhanced medical treatment grows up, Purchasing step which include medical engineer's opinion has to be required. On this procedure, Medical Engineer Departments has used $\ulcorner$comparision chart$\lrcorner$. In this paper, How to compose and utilize comparison chart for purchasing of medical equipment by medical engineer in the hospital. It is made through the technical and objective investigation. From these points, We think that it can be available for proper installation and improved maintenance.

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Siderophore Production by Rhizosphere Biological Control Bacteria Brevibacillus brevis GZDF3 of Pinellia ternata and Its Antifungal Effects on Candida albicans

  • Sheng, Miaomiao;Jia, Huake;Zhang, Gongyou;Zeng, Lina;Zhang, Tingting;Long, Yaohang;Lan, Jing;Hu, Zuquan;Zeng, Zhu;Wang, Bing;Liu, Hongmei
    • Journal of Microbiology and Biotechnology
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    • v.30 no.5
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    • pp.689-699
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    • 2020
  • Brevibacillus brevis GZDF3 is a gram-positive, plant growth-promoting rhizosphere bacterium (PGPR) isolated from the rhizosphere soil of Pinellia ternata (an important herb in traditional Chinese medicine). The GZDF3 strain produces certain active compounds, such as siderophores, which are the final metabolite products of non-ribosomal peptide synthetase (NRPS) and independent non-ribosomal peptide synthetase (NIS) activity. With the present study, we attempted to investigate the siderophore production characteristics and conditions of Bacillus sp. GZDF3. The antibacterial activity of the siderophores on pathogenic fungi was also investigated. Optimal conditions for the synthesis of siderophores were determined by single factor method, using sucrose 15 g/l, asparagine 2 g/l, 32℃, and 48 h. The optimized sucrose asparagine medium significantly increased the production of siderophores, from 27.09% to 54.99%. Moreover, the effects of different kinds of metal ions on siderophore production were explored here. We found that Fe3+ and Cu2+ significantly inhibited the synthesis of siderophores. The preliminary separation and purification of siderophores by immobilized-metal affinity chromatography (IMAC) provides strong antibacterial activity against Candida albicans. The synergistic effect of siderophores and amphotericin B was also demonstrated. Our results have shown that the GZDF3 strain could produce a large amount of siderophores with strong antagonistic activity, which is helpful in the development of new biological control agents.

The Effect of Pulsatile Flow on Ultrafiltration In-Vitro Study and Comparison with Roller Pump

  • Lee K.;Jeong J. H.;Mun C. H.;Lee J. C.;Min B. G.
    • Journal of Biomedical Engineering Research
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    • v.26 no.5
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    • pp.337-341
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    • 2005
  • Blood pulsation has been reported to have an advantageous effect on extracorporeal blood circulation. However, the study of pulsatile blood flow in renal replacement therapy is very limited. The in-vitro experimental results of pulsatile blood flow on ultrafiltration, when compared with the conventional roller pump, are described in this paper. Methods: Blood flow rate (QB) and transmembrane pressure (TMP) were considered as regulating factors that have an influence on ultrafiltration. Experiments were performed under the condition of equal TMP and OB in both pulsatile and roller pump groups, Several kinds of hollow fiber dialyzers were tested using distilled water containing chemicals as a blood substitute. Mean TMP (mTMP) varied from 10 to 90mmHg while the QB was 200ml/min. Results: Ultrafiltration rate (QUF) was found to be linearly proportional to TMP, whereas QB had little influence on QUF. In addition, QUF was higher in the pulsatile group than the roller pump group at the identical TMP. Conclusion: In the controlled test, QUF increased solely as a consequence of blood pulsation, which implies that the pulse frequency represents an additional and important clinical variable during renal replacement therapy.