• Parasites, Hosts and Diseases
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• 제53권5호
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• pp.583-595
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• 2015

DEAD/DExH-box RNA helicases catalyze the folding and remodeling of RNA molecules in prokaryotic and eukaryotic cells, as well as in many viruses. They are characterized by the presence of the helicase domain with conserved motifs that are essential for ATP binding and hydrolysis, RNA interaction, and unwinding activities. Large families of DEAD/DExH-box proteins have been described in different organisms, and their role in all molecular processes involving RNA, from transcriptional regulation to mRNA decay, have been described. This review aims to summarize the current knowledge about DEAD/DExH-box proteins in selected protozoan and nematode parasites of medical importance worldwide, such as Plasmodium falciparum, Leishmania spp., Trypanosoma spp., Giardia lamblia, Entamoeba histolytica, and Brugia malayi. We discuss the functional characterization of several proteins in an attempt to understand better the molecular mechanisms involving RNA in these pathogens. The current data also highlight that DEAD/DExH-box RNA helicases might represent feasible drug targets due to their vital role in parasite growth and development.

• 한국치위생학회지
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• 제19권3호
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• pp.399-408
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• 2019

Objectives: In this study, by a professional who provides medical services by gauging the level of personality recognition among dental hygienists, the basic data is provided to suggest the need for personality education in dental hygienists' education. Methods: A questionnaire survey was conducted with the members attending conservative education in 2018, and the results of the analysis of the total of 348 members were as follows. Results: The average age of the participants was 31.6 years, and their average career duration was 9.4 years. The total personality score was 3.74 points. The highest score was 4.10 points for conscience, and the lowest score was 2.98 points for habit. In terms of differences between general characteristics and personality domains, the personality perception score was statistically significantly higher for hygienists who were married than for those with a higher education level and working at a higher hospital level. There was a statistically significant positive correlation between the personality domains and the highest competence domain (r=0.790) in relation to total personality. The higher the competency, the higher the total score. Conclusions: Personality is not a part of being formed in the short term. It should be recognized that it is important to recognize the importance of personality in the dental hygiene education curriculum and to provide opportunities to develop personality through systematic programs.

• 대한통합의학회지
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• 제12권1호
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• pp.161-169
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• 2024

Purpose : This study investigated the correlation between social support and older people's quality of life. Methods : We conducted a questionnaire survey with 350 older participants and analyzed 320 completed surveys. The collected data were analyzed using SPSS 25.0 for Windows. The general characteristics of the participants and quality of life subdomains were analyzed using descriptive statistics and frequency analyses. Furthermore, the differences between the subdomains of social support and quality of life were analyzed using independent t-tests and a one-way ANOVA. Post-hoc tests were performed using the Scheffé test. A significance level of α=.05 was used to verify statistical significance. Results : Upon examining the sub-domain level of social support and considering general characteristics, it was found that older age correlates with increased dependency among patients with associated diseases (p<.05). Similarly, an investigation into participants' quality of life at the subdomain level, considering general characteristics, revealed higher correspondence to lower quality of life (p<.05). Differences emerged between social support and quality of life among older individuals, with a negative correlation observed between the two (p<.05). Conclusion : This study suggests the importance of actively supporting older people with chronic diseases who experience emotional and psychological instability. It advocates for promoting the use of various services, including visiting medical services, convalescent care, and assistance, to meet their needs effectively.

• 한국간호교육학회지
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• 제9권2호
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• pp.320-328
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• 2003

Nurse educators' competence is considered to be important in relation to the quality of education for nursing students. The purpose of this study was to identify the nursing faculty competence and attitude for lecture evalutaion, evlauated by nursing faculty. This article presented results focusing on South Korean nursing faculty's attutude for lecture evalutaion done by students and their opinion of the importance of nurse educator competence domains. The data collection was done from October, 2002 to August, 2003 and 151 subjects were used for the analysis. The Ideal Nursing Teacher Questionnaire was used to assess nurse faculty competence. The results showed that all of the lecture were evaluated and 59.6% of clinical practice was evaluated by nursing studuents. Nursing faculty thought that lecture evaluation by students was resonable, even though it was stressful. The most important among 5 domains of nurse educators' competence assessed by nursing faculty was nursing competence. Moreover nursing faculty responed that teaching skills domain and evaluation skills domain were more important than relationship with students domain and personality factors domain. Compared to young nursing faculty, nursing faculty who was old aged reported that nurse educators' competences in 4 domains of nursing competence, teaching skills, evaluation skills and relationship with students were more important.

• 지식경영연구
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• 제25권2호
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• pp.155-176
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• 2024

본 연구는 의료 및 금융 서비스 영역에 대해 인간과 AI 에이전트에 대한 소비자의 선호도가 어떻게 달라지는지 확인하고자 하였다. 연구 1은 각 서비스 영역에서 인간과 AI 에이전트 중 소비자가 선호하는 정도에 차이가 있는지 확인하였으며, 그 결과, 의료 서비스에 대해서는 AI 에이전트보다 인간 에이전트가 더 선호되고, 금융 서비스에서는 이와 반대로, 인간 에이전트가 보다 AI 에이전트가 더 선호되는 결과가 나타났다. 연구 2는 의료 및 금융 서비스 영역에 대한 인간-AI 에이전트 선호도가 달라지는 이유를 각 서비스 영역별로 소비자가 지각하는 특정 능력(예: 지각된 공감 능력, 경험치, 주체성)의 중요성의 차이로 설명할 수 있는지 확인하고자 하였다. 그 결과, 서비스 영역에 따른 인간-AI 에이전트 선호도 경향이 소비자가 지각하는 공감 능력의 중요성에 의해 매개된다는 것을 확인하였다. 또한, 지각된 공감 능력이 다른 능력들(경험치, 주체성)에 비해, 두 서비스 영역 간 인간-AI 에이전트 선호를 결정하는 데 더 중요한 역할을 하는 것을 확인하였다. 본 연구는 의료 및 금융 서비스 영역에 대해서 인간과 AI 에이전트에 대한 소비자의 선호도 차이와 그 이유를 확인한 연구라는 점에서 의의가 있다. 이는 인간과 AI 에이전트 선호도에 영향을 미치는 잠재적으로 중요한 요인들에 대한 이론적 이해를 확장하고, 서비스 영역에 따라, 지각된 공감 능력과 같이 인간의 경험적 역량이 인간과 AI 에이전트 선호도를 결정하는데 중요한 역할을 할 수 있다는 점을 강조한다.

• 한국정보통신학회논문지
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• 제15권2호
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• pp.292-298
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• 2011

생체신호 데이터의 의미와 그들 간의 연관관계를 정의하여 새로운 정보를 획득할 수 있는 형태의 모델링방법으로 온톨로지가 제시되고 있다. 온톨로지를 이용하여 생체신호 데이터를 지속적으로 관리함으로써 생체 신호 데이터의 체계적이고 논리적으로 표현이 가능하고, 이는 나아가 의료정보, 건강서비스 등 다양한 분야에서 질적으로 향상된 서비스를 제공하게 해주는 지식 자원으로 활용된다. 하지만 현재로는 생체 신호간의 연관 관계 중요성에 비해서 관련 연구가 활발하게 이루어지지 않고 있다. 따라서 생체 신호간의 연관관계를 찾아서 정의하고, 생체정보간의 의미표현이 필요하다. 그러기 위해서는 다양한 생체정보간의 연관 관계를 통해 체계적이고 구조화 된 정보를 만드는 것이 필요하다. 본 논문에서는 생체정보를 체계적이고 구조화 된 도메인 지식으로 활용하기 위한 모델로써 온톨로지를 이용하여 생체정보 온톨로지를 구축하고, 시나리오를 통해서 생체정보 온톨로지의 유용성을 검증하였다.

• 중환자간호학회지
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• 제12권3호
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• pp.50-60
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• 2019

Purpose : The purpose of this study was to explore and describe the meanings of hands among clinical nurses. Methods : A descriptive qualitative study design was used. Participants were 1,048 nurses working in a tertiary hospital in G city. From April to May 2018, an open-ended survey on how nurses felt about their hands and what their hands meant to them was conducted. The collected data were analyzed using MAXQDA 2018 version as well as content analysis. Results : A total of 1,048 pieces of data were analyzed, and 2,094 units of analysis were categorized based on their attributes, resulting in physical, emotional, and social domains. The data in the social domain were reported in a narrative format; thus, they were analyzed using content analysis. Three themes and eight sub-themes were elicited. The three themes included "meaning as an instrument," "meaning of infection control," and "meaning of caring." Conclusion : Nurses imbue essential meanings of caring on their hands even though they face negative skin symptoms. Furthermore, nurses understand the importance of hand hygiene on infection control. The findings of this study provide an in-depth look into nurses' perceptions of their hands.

• 디지털융복합연구
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• 제17권1호
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• pp.219-227
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• 2019

본 연구는 보건계열 학생을 대상으로 환자안전 지식과 환자안전 수행자신감을 파악하기 위해 수행되었다. 보건계열학생 349명이 참여하였고, 자료분석은 SPSS 21.0을 이용하여 분석하였다. 연구결과 환자안전지식 정답률은 평균 65.7%였다. 환자안전 수행자신감은 평균 $7.11{\pm}1.74$점이었으며 문항별로 살펴보면 환자확인이 높았으며 효과적 의사소통이 낮게 나타났다. 환자안전지식과 환자안전 수행자신감의 하부영역인 환자확인, 의사소통, 수술시술, 낙상, 환자안전사고보고는 양의 상관관계였고, 환자안전지식과 감염관리, 시설환경은 음의 상관관계였다. 보건계열학생들에게 임상실습 전 환자안전에 대한 중요성을 높이고 안전한 임상실습이 수행될 수 있도록 환자안전교육프로그램을 개발하는 것이 필요하다.

• 동의생리병리학회지
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• 제38권2호
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• pp.49-58
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• 2024

The rapid advancement of generative large language models has revolutionized various real-life domains, emphasizing the importance of exploring their applications in healthcare. This study aims to examine how generative large language models are implemented in the medical domain, with the specific objective of searching for the possibility and potential of integration between generative large language models and East Asian medicine. Through a comprehensive current state analysis, we identified limitations in the deployment of generative large language models within East Asian medicine and proposed directions for future research. Our findings highlight the essential need for accumulating and generating structured data to improve the capabilities of generative large language models in East Asian medicine. Additionally, we tackle the issue of hallucination and the necessity for a robust model evaluation framework. Despite these challenges, the application of generative large language models in East Asian medicine has demonstrated promising results. Techniques such as model augmentation, multimodal structures, and knowledge distillation have the potential to significantly enhance accuracy, efficiency, and accessibility. In conclusion, we expect generative large language models to play a pivotal role in facilitating precise diagnostics, personalized treatment in clinical fields, and fostering innovation in education and research within East Asian medicine.

• Journal of Preventive Medicine and Public Health
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• 제57권2호
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• pp.138-147
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• 2024

Objectives: Fine particulate matter pollution has emerged as a significant life-threatening issue in Thailand. Recognizing the importance of environmental health literacy (EHL) in disease prevention is crucial for protecting public health. This study investigated EHL levels and aimed to identify associated factors among village health volunteers (VHVs) in the upper northern region of Thailand. Methods: A cross-sectional study was conducted to collect data from 710 VHVs using the EHL assessment tool developed by the Department of Health, Thailand. Results: The overall EHL score was moderate (mean, 3.28 out of a possible 5.0), with the highest and lowest domain-specific mean score for the ability to make decisions (3.52) and the ability to access (3.03). Multiple linear regression revealed that the factors associated with EHL score were area of residence (urban areas in Chiang Mai: B=0.254; urban areas in Lampang: B=0.274; and rural areas in Lampang: B=0.250 compared to rural areas in Chiang Mai), higher education levels (senior high school: B=0.212; diploma/high vocational certificate: B=0.350; bachelor's degree or above: B=0.528 compared to elementary school or lower), having annual health checkups compared to not having annual health check-ups (B=0.142), monthly family income (B=0.004), and individuals frequently facing air pollution issues around their residence (B=0.199) compared to those who reported no such issues. Conclusions: The VHVs exhibited moderate EHL associated with residence area, education, health check-ups, family income, and residential air pollution. Considering these factors is vital for enhancing VHVs' EHL through strategic interventions.