• Title/Summary/Keyword: Medical Application

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Progress in the Direct Application of Pharmacogenomics to Patient Care: Sustaining innovation

  • Frueh, Felix W.;Lesko, Lawrence J.;Burckart, Gilbert J.
    • Biomolecules & Therapeutics
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    • v.15 no.1
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    • pp.1-6
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    • 2007
  • The application of the knowledge from the Human Genome Project to clinical medicine will be through both industrial drug development and the application of pharmacogenomics (PG) to patient care. The slow uptake of clinical innovations into clinical practice can be frustrating, but understanding the history of acceptance and sustaining medical innovation is critically important to position PG to succeed. This primarily means that PG tests must have legitimacy; they must be thoroughly validated, must be cost-effective, must be widely accepted by medical practitioners, must be supported by public policy, and must have a way of being easily incorporated into current medical practice. They must also lead to actionalble decisions by health care providers for their patients. Innovative PG assays should be tested in the best US laboratories, and reimbursement for testing must be accepted at the federal and state level. The companies providing these PG tests should be capable of sup-porting the interpretation and use of the test throughout medical practice. Advances such as the addition of PG information to drug labeling and the routine use of validated biomarkers to determine choice of cancer chemotherapy have been made. The PG research community must pay attention to the principles that have been previously described for acceptance and sustaining medical innovations in order for PG to be widely accepted in clinical medical practice.

Medical Application of Synchrotron Radiation in Japan

  • Toyofuku, Fukai;Tokumori, Kenji;Hyodo, Kazuyuki;Ando, Masami;Uyama, Chikao
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.32-34
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    • 2002
  • Over the past two decades there has been a tremendous growth in the number of synchrotron radiation facilities in the world and also in Japan. The high flux and brightness radiation which derive from the third generation low emittance rings provide an ideal source for many applications in the medical sciences. The application of synchrotron radiation to medical imaging started in the early 80's in U.S.A, followed by European countries such as Germany and Russia. In Japan, researchs on intravenous coronary angiography started in 1884 at the Institute for High Energy Phisics(KEK) in Tsukuba. At present, it is the only application of syncrotron radiation which is at the stage of human study. In '90s, newer techniques such as phase and refraction contrast imaging appeared which are at the in vitro or animal study stage. Various types of x-ray CT have also been developed for three-dimensional imaging of the subjects. The present status of medical applications of synchrotron radiation in Japan is reviewed.

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Clinical Application of the Spleen Daoyin Method(脾臟導引法) in the 『Donguibogam(東醫寶鑑)』 (『동의보감(東醫寶鑑)』 비장도인법(脾臟導引法)의 임상적 활용)

  • Kim, Yuna;Baik, You-sang;Jeong, Chang-hyun;Jang, Woo-chang
    • Journal of Korean Medical classics
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    • v.34 no.2
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    • pp.107-126
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    • 2021
  • Objectives : To discuss the therapeutic properties of Daoyin, and suggest ways to apply the Spleen Daoyin Method clinically. Methods : The therapeutic properties of Daoyin were examined in medical texts, after which the movements and effects of the Spleen Daoyin Method were analyzed. Based on relevant contents in the Donguibogam, symptoms and diseases for application of the Spleen Daoyin Method were studied to suggest further clinical application possibilities. Results & Conclusions : Daoyin manages the body by treating diseases, while keeping the Shen intact to manage the mind. In the case of the Five Zhang Daoyin Method, its therapeutic nature is clear as the target is focused on the Five Zhang. The Spleen Daoyin Method is mostly comprised of two movements that enable overall restoration and improvement of the Spleen function. Therefore, it could be applied in cases of Spleen-Stomach diseases where there is functional damage.

Progress in the Direct Application of Pharmacogenomics to Patient Care: Sustaining innovation

  • Burckart, Gilbert J.;Frueh, Felix W.;Lesko, Lawrence J.
    • 한국약용작물학회:학술대회논문집
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    • 2006.11a
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    • pp.23-39
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    • 2006
  • The application of the knowledge from the Human Genome Project to clinical medicine will be through both industrial drug development and the application of pharmacogenomics (PG) to patient care. The slow uptake of clinical innovations into clinical practice can be frustrating, but understanding the history of acceptance and sustaining medical innovation is critically important to position PG to succeed. This primarily means that PG tests must have legitimacy; they must be thoroughly validated, must be cost-effective, must be widely accepted by medical practitioners, must be supported by public policy, and must have a way of being easily incorporated into current medical practice. They must also lead to actionalble decisions by health care providers for their patients. Innovative PG assays should be tested in the best US laboratories, and reimbursement for testing must be accepted at the federal and state level. The companies providing these PG tests should be capable of supporting the interpretation and use of the test throughout medical practice. Advances such as the addition of PG information to drug labeling and the routine use of validated biomarkers to determine choice of cancer chemotherapy have been made. The PG research community must pay attention to the principles that have been previously described for acceptance and sustaining medical innovations in order for PG to be widely accepted in clinical medical practice.

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Application of artificial intelligence in medical education: focus on the application of ChatGPT for clinical medical education (의학 교육에서 인공지능의 응용: 임상의학 교육을 위한 ChatGPT의 활용을 중심으로)

  • Hyeonmi Hong;Youngjoon Kang;Youngjon Kim;Bomsol Kim
    • Journal of Medicine and Life Science
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    • v.20 no.2
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    • pp.53-59
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    • 2023
  • This study explores the potential use of artificial intelligence (AI)-based services, specifically ChatGPT-3.5, in medical education. The application of this technology is acknowledged as a valuable tool for simulating authentic clinical scenarios and enhancing learners' diagnostic and communication skills. To construct a case, students received ChatGPT training using a clinical ethics casebook titled "Clinical Ethics Cases and Commentaries for Medical Students and Physicians." Subsequently, a role-play script was generated based on this training. The initial draft of the script was reviewed by two medical professors and was further optimized using ChatGPT-3.5. Consequently, a comprehensive role-play script, accurately reflecting real-world clinical situations, was successfully developed. This study demonstrates the potential for effectively integrating AI technology into medical education and provides a solution to overcome limitations in developing role-play scripts within conventional educational settings. However, the study acknowledges that AI cannot always generate flawless role-play scripts and recognizes the necessity of addressing these limitations and ethical concerns. The research explores both the potential and limitations of employing AI in the early stages of medical education, suggesting that future studies should focus on overcoming these limitations while further investigating the potential applications of AI in this field.

Comparison of Pain Management between before and after the Application of Guidelines in Cancer Emergency Room (암성통증관리지침 적용 전후 긴급진료실 내원 환자의 통증관리 비교)

  • Won, Young-Hwa;Kim, Yeon-Hee;Park, Jeong-Yun
    • Asian Oncology Nursing
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    • v.12 no.3
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    • pp.230-236
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    • 2012
  • Purpose: This study was to investigate the effect of the application of cancer pain management guidelines on pain management among patients in Cancer Emergency Room. Methods: This study was a retrospective descriptive study. Before application, data were collected by analyzing the Electronic Medical Record in Cancer Emergency Room in September, 2011, and after application in February, 2012. The subjects of this study consisted of 231 patients (pre-application group 83, post-application group 148), who stayed over 24 hours and complained of pain higher than Numeric Rating Scale score 4. The post-test was conducted after educating the nurses about the application of the pain management guidelines in the Electronic Medical Record. Results: This survey showed that, as the cancer pain management guidelines were applied for cancer patients with above moderate pain, the pain intensity decreased, the number of patients reaching the treatment goal score increased. Furthermore, the estimated time to reach the treatment goal decreased significantly. Conclusion: Pain intensity of the cancer patients was decreased through regular pain assessments by nurses and the medication of analgesics according to the cancer pain management guidelines. Therefore, it is necessary to develop the pain management program and to provide the physicians and nurses with intensive education about the pain management guidelines for systematic and effective pain management.

Development of color space conversion algorithm for application of tooth colorimetry app (치아측색용 App 적용을 위한 색공간 변환 알고리즘 개발)

  • Jo, Jae-Hyun;Kim, Seung-Hun;Lee, Sang-Sik;Jeong, Jin-Hyoung
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.15 no.1
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    • pp.62-68
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    • 2022
  • Due to medical and economic development, various treatment methods are being studied to restore or maintain beautiful and healthy teeth. In particular, interest in aesthetic treatment procedures such as prosthetic treatment and whitening to restore tooth loss is increasing. One of the important things in the field of prosthetics and esthetic treatment is to determine the correct color of teeth because harmony with natural teeth is an important factor in determining the perfection of esthetic prostheses. This study is about the development of a colorimetry application for tooth colorimetry using a smartphone camera. The colorimetry application UI was designed, the colorimetry algorithm was derived and the application was implemented, and the validity of the application was verified through testing the implemented application.

Optical Simulation of Direct-type Backlight Unit for Medical Application

  • Han, Jeong-Min;Han, Jin-Woo;Seo, Dae-Shik
    • Transactions on Electrical and Electronic Materials
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    • v.9 no.1
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    • pp.16-19
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    • 2008
  • In this study, it was investigated about optical simulation in direct-type backlight design. Direct-type backlight has been used high-brightness backlight such as medical LCD application. The key parameter in designing direct-type backlight was consists of three geometrical dimension such as the distance of two lamps, the gap of lamp and reflection plate and the number of lamps. It has many of variations in optical design and it causes the different properties in backlight system. It shows the best values of above parameters; 26 mm of the distance of two lamps, 4.5 mm of the gap of lamp and reflection plate and 16 lamps. And we produced the specimen as above condition, and acquired good result in backlight such as the value of the brightness is 6423 nit in center of emission area and less than 5 % in brightness uniformity. It shows the effective ways of designing backlight system using optical simulation method for medical LCD application.

Evaluation of the Bar Code Medication Administration and Blood Transfusion System in a Tertiary Hospital (투약.수혈 바코드 시스템 적용 평가)

  • Cho, Myung-Sook;Song, Mi-Ra;Jang, Mi-Ra
    • Journal of Korean Academy of Nursing Administration
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    • v.18 no.1
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    • pp.23-32
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    • 2012
  • Purpose: The purpose of this study was to assess the clinical application of a bar code medication administration and blood transfusion system and to identify its effects from the aspect of patient safety and nurse satisfaction in a tertiary hospital. Methods: The system in this study was PDA with bar code reading capability and wireless networking function. The logs created during application of the system and administration error reports were analyzed. For nurses' satisfaction with the system, data were collected from 337 nurses using the instrument developed by Otieno et al. and analyzed using descriptive statistics. Results: The system application rate was 98.8%, and the main failure cases in the system application included bar code or network related factors. When the system was applied, 0.02% of errors were prevented. The nurses were satisfied with the system from the aspect of patient safety, however relatively less satisfied with the system from the aspect of work efficiency. Conclusion: The results of the study indicate the usefulness for patient safety of applying the bar code medication administration and blood transfusion system to clinical practice. However technological improvements including bar code and network communication are necessary to ensure higher work efficiency in nursing practice.