• Archives of Aesthetic Plastic Surgery
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• 제23권3호
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• pp.143-145
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• 2017

Medical leech therapy is a treatment for the venous congestion of tissue flaps, grafts, and replants. We report a case of methicillin-resistant Staphylococcus aureus (MRSA) following leech application at a congested flap after mastectomy. A 45-year-old woman had an invasive ductal carcinoma. Modified radical mastectomy was performed. The chest wall defect was reconstructed with a local rotation flap. On postoperative day (POD) 1, congestion and color change were observed, and 10 medical leeches were applied to the congested area. On POD 4, another 10 medical leeches were applied. On POD 12, wound necrosis progressed and a pus-like discharge appeared. A wound swab culture revealed MRSA. Debridement was carried out on POD 15. From POD 16, vancomycin and piperacillin/tazobactam were injected for 18 days. The wound culture on POD 18 also revealed MRSA. A split-thickness skin graft was performed on POD 28. MRSA has not been clearly identified in the literature as a leech enteric bacterium. Although MRSA may have come from another source, the present case raises the possibility of MRSA infections following leech application at congested flaps. When medical leeches are applied at the congestion site of a flap, an aseptic cradle will be helpful. Vancomycin irrigation may be needed if infection occurs.

• 대한한의학원전학회지
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• 제36권2호
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• pp.77-96
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• 2023

Objectives : The purpose and application method of the five kinds of Gagamjeong-gisan in the Onbyeongjobyeon were analyzed and their significance was examined. Methods : First, contents within medical texts on the Gwakhyangjeong-gisan, the original formula for the Gagamjeong-gisan were analyzed. Next, application, symptoms and pathogenic mechanism, treatment principle, composition of the Gagamjeong-gisan as written in the Onbyeongjobyeon were analyzed. Characteristics of each formula as deduced from this process were compared and examined. Results : The Gwakhyangjeong-gisan covers both external contraction and internal damage, applied regardless of external or internal symptoms. It restores the Yang qi of the Spleen and Stomach, balancing the Zheng qi to respond to the external qi. The Gagamjeong-gisan takes after the Gwakhyangjeong-gisan, reflecting such properties. However, the latter differs in that it excludes ingredients unfit for treating dampness-warmth, and uses different application methods according to the level of discharge of dampness pathogen. Conclusions : The Gagamjeong-gisan is modified from the Gwakhyangjeong-gisan, which is applied to cold damage and internal damage to better treat warm disease. It can be said to have acted as a bridge for warm disease scholars in composing formulas that deal with dampness-heat disease.

• 전자공학회논문지CI
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• 제49권1호
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• pp.46-53
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• 2012

WBAN(Wireless Body Area Network) 기술은 인체 내부 및 외부에 부착한 디바이스들을 무선으로 연결하여 통신할 수 있는 근거리 무선 통신 기술로서 IEEE 802.15.6 TG BAN을 중심으로 물리 계층, 데이터 링크 계층, 네트워크 계층 및 응용계층 등에서 표준화가 진행되고 있다. WBAN 환경을 지원하기 위해서는 센서 노드 디바이스 뿐만 아니라 WBAN 미들웨어 및 WBAN 응용 서비스 등의 WBAN 핵심 기술의 개발이 필요하다. 본 논문에서는 3G, 4G, WiFi를 통하여 환자의 생체 정보를 정확하고 신속하게 전달하기 위한 목적으로 WBAN 환경을 위한 의료용 메시지 구조를 설계하고 WBAN 게이트웨이 관리 엔진을 통하여 BN으로부터 들어온 환자의 생체 정보를 스마트폰에서 확인할 수 있는 의료용 애플리케이션을 구현하였다.

• 대한한의학원전학회지
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• 제36권1호
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• pp.45-78
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• 2023

Objectives : Based on the Zangfuyaoshibuzheng of Zhang Shanlei, this paper examines the tip/root division of the Zangfu, features of medicinal application according to deficiency/excess or cold/heat, and erroneous cases in the Zangfuxushibiaobenyongyaoshi of Zhang Jiegu. Methods : Categorization according to tip/root, cold/heat, deficiency/excess and respective medicinal applications in the Zangfuxushibiaobenyongyaoshi were organized, followed by thorough analysis based on the annotations in the Zangfuyaoshibuzheng. Results : First, in the treatment principle of the Zangfu diseases, each of their physiological function and pathological mechanism were analyzed so that the disease patterns are understood accurately and treated accordingly. Second, in categorizing treatment methods, terminology application was modified in overlapping or ambiguous cases so that they could be better distinguished. Third, medicinal categories that were designated to treat each Zangfu disease were explained well based on unique features. In cases where medicinals were falsely included, they were identified and corrected based on sound reasoning. Conclusions : The pattern diagnosis in the Zangfuyaoshibuzheng is clear, and medicinal application analysis is intelligible. As it thoroughly corrects and revises errors in Zhang Jiegu's theories, it could provide valuable assistance in selecting each medicinals when treating disease patterns of the Five Zang.

• 대한의용생체공학회:의공학회지
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• 제43권4호
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• pp.199-213
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• 2022

EN ISO 14971:2012 a risk management standard approved and applied as a European standard in 2012, will be adopted and applied as ISO 14971:2019 published in December 2019, ISO/TR 24971(Guidance) published in June 2020 from May 2022. After that, it is applied to IVDD surveillance and IVDR new and conversion, and the manufacturer is already preparing for application or is starting preparation for application. In addition, 98/78/EEC IVDD applied from 1998 will also be applied as REGULATION (EU) 2017/746 IVDR from May 2022. In particular, in IVDR, the requirements for post-marketing investigations such as Post Market Surveillance (PMS), Summary of safety and performance(SSP), Periodic Safety Update Report(PSUR) and Post Market Performance Follow Up(PMPF), which were not required in the existing IVDD, increased, and the contents were also specified. This study focused on ISO14971:2019 among these strengthened and newly applied regulations, and tried to present a detailed analysis and application plan of Post Market Surveillance (PMS) required by 2017/746 IVDR.

• 대한방사선기술학회지:방사선기술과학
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• 제38권3호
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• pp.213-220
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• 2015

본 연구는 3차원 입체정위 유방생검술의 정확도를 알아보고, 심부침생검을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도를 평가하고자 한다. Stereotactic QC phantom을 이용하여 실제 5개의 target 위치로 3D sterotactic machine의 정확도를 측정하고, CT장비로 Scan하여 실측을 구해 X, Y, Z의 길이의 정밀도를 비교한다. 유방조직과 유사하게 제작한 Agar power phantom을 이용하여 5개의 각기 다른 needle tip Target을 통해 3D sterotactic machine과 2D ultrasound machine의 정확도를 비교하고, Z축을 장비별로 실측하여 정밀도와 신뢰도를 비교하며, 6개의 모조병소 Target을 심어놓은 Medical application phantom으로 표적하여 육안검사와 Specimen검사를 통해 정확도를 확인하였다. Stereotactic QC phantom으로 측정한 3D sterotactic machine의 정확도는 100%였으며, CT와 비교한 정밀도는 X, Y, Z축이 모두 p>0.05로 나타났다. Agar powder phantom으로 측정한 두 장비의 정확도는 100%의 정확도를 보였으며, CT와 두 장비 사이에는 p > 0.05로 차이가 없었다. 그러나 2명의 방사선사가 측정한 신뢰도분석에서 3D sterotactic machine은 ICC가 0.954였고, 2D ultrasound machine은 0.785로 2D ultrasound machine이 술자에 따라 차이가 있었다. Medical application phantom의 실험에서 3D sterotactic machine은 Sliced boneless ham을, 2D ultrasound machine은 small chalk powder group를 찾을 수 없었다. Phantom을 이용한 3차원 입체정위 유방생검술의 정확성은 우수하게 나타났고, 인체조직과 비슷한 Agar powder phantom과 유방 조직과 비슷한 Medical application phantom을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도 모두 우수하게 나타났다. 또한 Medical application phantom의 심부침생검의 정확성 평가에서 각 검사에 따라 생검 표본이 병소의 형태에 따라 상이하게 채취되었고, 3차원 입체정위 유방생검술의 재현성이 유방 초음파검사보다 술자의 영향없이 우수하였다.

• 한국동물학회지
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• 제24권3호
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• pp.151-161
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• 1981

水畓棲息의 主要 모기 幼蟲과 기타 昆蟲의 個體群密度를 調査하기 위하여 京畿道 高揚郡 條里面 廣탄 3里의 一個 自然部落을 調査地域으로 選定하여 1980年 6月부터 9月末까지 週別로 채집을 實施하였다. 1. Culex tritaeniorhynchus 幼蟲 個體群密度의 계절적 변동은 다량의 降雨후에 급격한 증가 형상을 보였고 살충제 살포에 대해서 어느정도의 감소 영향을 받았다. 2. Anopheles sinensis 幼蟲의 個體群密度는 계절적으로 안정되어 있어 큰 변동을 나타내지 않았으며 강수량과 살충제 살포에 영향을 받지 않았다. 3. Odonata와 Ephemeroptera의 경우는 살충제 살포가 결정적인 억제 요인으로 작용하여 Odonata는 6월 중순의 첫 살포후에, Ephemeroptera는 7월 중순의 두 번째 살포후 각각 완전히 자취를 감추었고 그 후 個體群密度의 회복은 불가능 하였다. 4. Coleoptera의 個體群密度는 週別 변동이 심하였으며 이는 主로 살충제 살포에 의한 결과로 해석된다. 살충제 살포 前週와의 비교에 의한 감소율을 보면 Coleoptera는 69.5% (幼蟲 75%, 成蟲 58.3%)였고, Hemiptera의 경우는 75.5%였다. 5. 水畓에 棲息하는 planaria 1種의 個體群密度는 강수량에 영향을 받으며 살충제 살포에 對한 억제효과는 없는 것으로 나타났다.

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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• pp.281.1-281.1
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• 2001

• International Journal of Quality Innovation
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• 제9권3호
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• pp.29-56
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• 2008

Since the execution of National Health Insurance system in Taiwan, the competition of medical industry is becoming more and more severe. The ways the hospital operate knowledge management (KM) concept, combine current human resources and professional knowledge by information techniques and upgrade the competitiveness through reinvention of organizational culture have become the important issues. This research is based on the relationship between KM and organizational operation, integrates the characteristic of medical institutions and framework of medical knowledge cycle and starts the research subject by questionnaires from three dimensions: current situation of KM construction in medical organizations, executive effect of KM activities and the challenges faced by KM; subsequently, from qualitative interview, this research attempts to understand how a medical organization executes and adjusts in the consideration of theory and reality as well as quality and costs when actually operates the organization. This research accesses to KM system application of medical institutions and the empirical executive benefits and difficulties through questionnaires. The research results are as follows: (1) having initial understanding toward current KM establishment of medical institutions; (2) confirming the most important items of KM establishment of medical organizations; (3) understanding the most difficulty which the medical organizations encounter when executing KM; (4) establishing medical knowledge cycle figure of the hospitals receiving interviews. Through case interview, this research profoundly accessed to the actual operation of KM application of medical organizations. The target hospitals intended to try many medical KM measures; however, during to complicated hospital organizations and cultural characteristics, the promotion was not successful and the results were not apparent. The most difficulty was to change the employees’ behavior. The targets believed that only the continuous promotion of KM can allow it to be an important aspect of organizational culture and the competitiveness could constant be upgraded.

• 대한의용생체공학회:의공학회지
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• 제44권3호
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• pp.204-210
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• 2023

This study focuses on analyzing medical device standards and regulatory requirements in the medical device industry, based on the Medical Device Act in Korea. The objective of this analysis is to determine whether the domestic standards for medical devices in Korea align with international and regional standards. Furthermore, it aims to identify the current application of domestic standards in ensuring the safety and essential performance of medical devices. The analysis revealed that out of a total of 281 domestic standards, 127 standards reference international standards. In terms of the application of domestic standards to specific items, there were 473 types of instruments/machines, 30 types of medical supplies, and 45 types of dental materials. However, the level of compliance with international standards among the domestic medical device standards was only 21%. Upon detailed analysis, general and collateral standards accounted for 24%, while particular standards accounted for 19%. This indicates a significant deviation from the latest international standards. On the other hand, the level of compliance with international standards was analyzed to be 60% for particular standards and 72% for general and collateral standards in Korean industrial standards (KS). Considering these results, the disparities between domestic standards and international standards underscore the need for discussions on domestic medical device regulation and standardization. In conclusion, this study emphasizes the significance of maintaining up-to-date medical device standards and ensuring their alignment with international standards to ensure the safety and quality of medical devices. The findings highlight the necessity for further efforts to strengthen the domestic standardization system in order to promote the development of safe and high-quality medical devices.