• 제목/요약/키워드: Medaka

검색결과 118건 처리시간 0.022초

EFFECT OF 17 $\beta$-ESTRADIOL ON MATING BEHAVIOR AND REPRODUCTIVITY OF MALE MEDAKA (ORYZIAS LATIPES)

  • Jisung Ryu;Lee, Chul-Woo;Park, Eung-Roh;Nam, Seong-Sook;Nam, Kyu-Chan;Rhu, Hong-Il;Jeon, Seong-Hwan;Na, Jin-Gyun;Park, Kwangsik
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.135-135
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    • 2001
  • Mating behavior and reproductivity of male fish were studied as an in vivo screening method of endocrine disruptors. Male medaka (Oryzias latipes) were exposed to 17$\beta$-estradiol at nominal concentrations of 2 and 20 $\mu\textrm{g}$/L for 14 days.(omitted)

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Neurobiochemical Analysis of Abnormal Fish Behavior Caused by Copper Toxicity

  • Shin, Sung-Woo;Cho, Hyun-Duk;Chon, Tae-Soo;Kim, Jong-Sang;Lee, Sung-Kyu;Koh, Sung-Cheol
    • 한국환경독성학회:학술대회논문집
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    • 한국환경독성학회 2003년도 춘계학술대회
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    • pp.156-157
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    • 2003
  • The goal of this study is to develop a biomarker used in monitoring abnormal behaviors of Japanese medaka (Oryzias latipes) as a model organism caused by hazardous chemicals. Japanese medaka was treated under appropriate sublethal concentrations of copper and the fish were subjected to copper treatment after starvation for 48 hr. The untreated individuals showed common behavioral characteristics (i.e., smooth and linear movements with small curvatures) in the movement behaviors.

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Neurobiochemical Analysis of Abnormal Fish Behavior Caused by Fluoranthene Toxicity

  • Shin, Sung-Woo;Cho, Hyun-Duk;Chon, Tae-Soo;Kim, Jong-Sang;Lee, Sung-Kyu;Koh, Sung-Cheol
    • 한국환경독성학회:학술대회논문집
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    • 한국환경독성학회 2003년도 춘계학술대회
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    • pp.158-159
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    • 2003
  • Fluoranthene, a common polycyclicaromatic hydrocarbon (PAH), exhibits phototoxicity which may affect aquatic organisms. The eventual goal of this study is to develop a biomarker used in monitoring abnormal behaviors of Japanese medaka (Oryzias latipes) as a model organism caused by hazardous chemicals that are toxic and persistent in the ecosystem. In this study, we investigated neural toxicity of fluoranthene in Japanese medaka (Oryzias latipes) which was correlated with its behaviors.

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송사리 모델계에서 구리 노출에 대한 생물지표로서 HSC70의 동정 (The Identification of HSC70 as a Biomarker for Copper Exposure in Medaka Fish)

  • 김우근;이성규;김정상
    • Environmental Analysis Health and Toxicology
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    • 제22권3호
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    • pp.197-202
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    • 2007
  • 구리는 환경에 광범위하게 존재하며, 생물체에게 필수적인 무기질이지만 고농도로 존재할 경우 독성을 발휘한다. 본 연구는 프로티옴 기술을 응용하여 수서태계에 구리와 같은 중금속의 존재 여부를 신속하게 평가하기 위한 생물지표를 발굴하기 위하여 수행되었다. 즉, 송사리(Oryzias latipes)를 이용하여 여러 농도의 구리용액(0.1, 1, 5 mg/L)에 24시간 노출시킨 다음, 머리부분에서 선택적으로 발현이 증가되는 단백질을 동정하고자 시도하였다. 본 시스템에서 유의적으로 발현이 증가하는 것으로 나타난 단백질은 beta-tubulin, heat shock cognate 70 (hsc70)이었으며, 이 결과의 일부를 semi-quantitative RT-PCR를 이용하여 확인하였다. 이와 같이 구리 처리에 특이적으로 발현이 증가된 송사리 단백질들은 노출평가를 위한 생물지표로서 개발을 위하여 더 연구할 가치가 있는 것으로 평가된다.