• 제목/요약/키워드: Mechanism factor

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고속카메라를 이용한 저항 점 용접의 너겟 형성 메커니즘 관찰 (Observation of Nugget Formation Mechanism by using High Speed Camera)

  • 조용준;이세헌
    • 대한용접접합학회:학술대회논문집
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    • 대한용접접합학회 2000년도 특별강연 및 추계학술발표대회 개요집
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    • pp.43-45
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    • 2000
  • Resistance Spot Welding has been one of the important process in the sheet metal fabrication of auto-body industry It is well known that the nugget formation of RSW is the major factor for the strength of the body. A high speed camera was used to consider initial melting and growth of the weld nugget in order to find out the nugget formation mechanism. It was observed that such mechanism had an effect on the dynamic resistance, which was a process parameter of resistance spot welding. Also, the relationship between the mechanism and process parameter was considered for the industrial application.

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안전한 로그인을 위한 소프트 보안카드 기반 다중 인증 시스템 (Multi-Factor Authentication System based on Software Secure Card-on-Matching For Secure Login)

  • 이형우
    • 한국콘텐츠학회논문지
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    • 제9권3호
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    • pp.28-38
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    • 2009
  • 로그인 과정에서는 사용자의 ID와 Password를 기반으로 시스템에 대한 사용권한을 확인하고 접근 권한을 부여한다. 하지만 로그인 과정에서 입력된 ID와 Password 정보는 패킷 스니핑 또는 키 로그(Key log) 프로그램 등을 이용하여 악의적인 공격자에 의해 노출될 수 있다는 취약점이 있다. 웹서버 또는 웹메일 시스템 등에 등록된 ID와 Password가 노출된다면 이는 개인 프라이버시 문제와도 연결되어 매우 심각한 문제를 야기한다. 본 연구에서는 기존의 ID/Password 기반 로그인 기법과 더불어 소프트웨어 형태의 보안카드를 핸드폰에 설치하여 유무선망을 통한 다중 인증(Multi-factor authentication) 기법을 제시한다. 제안한 소프트웨어 형태의 보안카드 기반 로그인 기법은 ID/Password와 함께 부가적으로 바이오 정보를 이용할 수 있으며 사용자의 핸드폰에 소프트 형태의 보안카드를 생성/전송/저장하게 된다. 따라서 제안한 시스템을 사용할 경우 기존의 ID 및 Password 정보에 대해 각 개인별 바이오 정보 기반 일회용 패스워드(Biometric One-Time Password) 방식으로 소프트 보안카드를 생성할 수 있으며 이를 이용하여 웹 및 인터넷 로그인 과정을 수행하기 때문에 보다 안전한 다중 인증 시스템을 구축할 수 있다.

The mechanism of human neural stem cell secretomes improves neuropathic pain and locomotor function in spinal cord injury rat models: through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities

  • I Nyoman Semita;Dwikora Novembri Utomo;Heri Suroto;I Ketut Sudiana;Parama Gandi
    • The Korean Journal of Pain
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    • 제36권1호
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    • pp.72-83
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    • 2023
  • Background: Globally, spinal cord injury (SCI) results in a big burden, including 90% suffering permanent disability, and 60%-69% experiencing neuropathic pain. The main causes are oxidative stress, inflammation, and degeneration. The efficacy of the stem cell secretome is promising, but the role of human neural stem cell (HNSC)-secretome in neuropathic pain is unclear. This study evaluated how the mechanism of HNSC-secretome improves neuropathic pain and locomotor function in SCI rat models through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities. Methods: A proper experimental study investigated 15 Rattus norvegicus divided into normal, control, and treatment groups (30 µL HNSC-secretome, intrathecal in the level of T10, three days post-traumatic SCI). Twenty-eight days post-injury, specimens were collected, and matrix metalloproteinase (MMP)-9, F2-Isoprostanes, tumor necrosis factor (TNF)-α, transforming growth factor (TGF)-β, and brain derived neurotrophic factor (BDNF) were analyzed. Locomotor recovery was evaluated via Basso, Beattie, and Bresnahan scores. Neuropathic pain was evaluated using the Rat Grimace Scale. Results: The HNSC-secretome could improve locomotor recovery and neuropathic pain, decrease F2-Isoprostane (antioxidant), decrease MMP-9 and TNF-α (anti-inflammatory), as well as modulate TGF-β and BDNF (neurotrophic factor). Moreover, HNSC-secretomes maintain the extracellular matrix of SCI by reducing the matrix degradation effect of MMP-9 and increasing the collagen formation effect of TGF-β as a resistor of glial scar formation. Conclusions: The present study demonstrated the mechanism of HNSC-secretome in improving neuropathic pain and locomotor function in SCI through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities.

SCH 양자우물 레이저 다이오드의 수송기구와 변조응답 특성에 관한 연구 (A Study on the Transport Mechanism of a SCH Quantum-Well Laser Diode and on the Modulation Characteristics)

  • 김종기;정재용;서정하
    • 대한전자공학회논문지TE
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    • 제37권1호
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    • pp.27-34
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    • 2000
  • 본 논문에서는 SCH 양자우물 구조를 가진 레이저 다이오드에서의 캐리어 수송기구와 변조응답 특성에 대해 고찰하였다. 캐리어 수송구조 고찰을 위해 캐리어 밀도분포및 다이오드전류를 계산하였다. 또한 우물내에서의 캐리어 재결합율을 SCH길이의 함수로 도출하였다. 변조응답 특성에서는 캐리어와 광자에 대한 3쌍의 비율 방정식을 도출, 해석하여 SCH 길이에 따른 변조 대역폭과 완화 진동 주파수, 감쇄 비율과 K-factor의 특성에 대하여 고찰하였다.

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과루인 에탄올 추출물의 혈관신생 억제효과 (Inhibitory Effect of the Ethanolic Seed Extract of Trichosanthes kirilowii on Angiogenesis in Human Umbilical Vein Endothelial Cells)

  • 박신형;박현지
    • 동의생리병리학회지
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    • 제36권5호
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    • pp.175-180
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    • 2022
  • The seeds of Trichosanthes kirilowii (STK) used in traditional Oriental medicine for the treatment of dry cough and constipation have diverse pharmacological activities, including hypolipidemic, antioxidant, immunosuppressive, and anticancer effects. However, the effect of STK on angiogenesis has not been studied yet. In this study, we investigated whether the ethanolic extract of STK (ESTK) can regulate the migration and tube formation of human umbilical vein endothelial cells (HUVECs) and explored the underlying mechanism. Results of transwell assay showed that ESTK treatment dose-dependently suppressed the migration of HUVECs. The conditioned medium collected from H1299 human lung cancer cells was used as a chemoattractant. Our observation suggests that ESTK would inhibit the recruitment of endothelial cells into tumors. In addition, ESTK treatment significantly reduced the tube formation of HUVECs. As a molecular mechanism, we found that vascular endothelial growth factor (VEGF)-induced phosphorylation of VEGF receptor 2 (VEGFR2) was completely blocked by ESTK treatment. The expression of angiogenic factors, including VEGFA, fibroblast growth factor 2 (FGF2), angiopoietin, placental growth factor (PGF), platelet derived growth factor (PDGF), angiogenin, and tumor necrosis factor (TNF)-α, was commonly decreased by ESTK treatment in H1299 cells, indicating that ESTK would reduce the production of angiogenic factors from cancer cells. Taken together, our results clearly demonstrated that ESTK exhibited anti-angiogenic effects in HUVECs, which provides another possible mechanism underlying the anticancer activities of STK.

무선 센서 네트워크에서 빠른 코드분배를 위한 다수분배자 선정 방법 (A Multiple-Disseminators Determining Mechanism for Fast Code Dissemination in Wireless Sensor Networks)

  • 김미희;홍준석
    • 한국IT서비스학회지
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    • 제10권2호
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    • pp.247-257
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    • 2011
  • In this paper, we propose a multiple-disseminators determining mechanism for Efficient Code Dissemination with low-delay(ECoDi) for wireless sensor networks (WSN). Code dissemination is in the spotlight as an important research issue since sensor nodes are necessary for updating new software remotely or fixing bugs dynamically. In particular, the time factor for code dissemination is the most important factor in order that the normal operation of nodes can be continuously performed as soon as finishing the dissemination. For this factor, ECoDi determines the set of disseminators through regression analysis based on the size of distributed code and the time of past unicasts and broadcasts. Then it transmits the entire code as a unicast to multiple disseminators, and the disseminators broadcast the code to the remaining neighbor nodes. Performance results on a testbed show that ECoDi reduces dissemination time significantly compared to a conventional scheme.

SET기반 전자상거래의 보안위협요소 분석 및 대응 방안에 관한 연구 (A Study on the Security Vulnerabilities and Defense Mechanism for SET-based Electronic Commerce)

  • 김상균;강성호
    • 한국전자거래학회지
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    • 제4권2호
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    • pp.59-79
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    • 1999
  • In order to construct a successful electronic commerce system, three main essential factors must be satisfied to obtain the best effective outcomes. The three main essential factors are as follows : economic factor, effectiveness factor and convenient factor. In order to understand the role of these three factors, one must have some insight knowledge about security to assist him to implement these three factors in his construction of an electronic commerce system. This paper analyses a implementation mechanism of security systems based on the SET 1.0 standard for electronic commerce systems, thus providing an effective plan for the construction of a security system in the SET-based electronic commerce field. This paper helps to analyse the elements of security vulnerabilities in the SET 1.0 standard implementation and also helps to understand the SET 1.0 protocol.

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