• 제목/요약/키워드: Measured Rate System

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자기공명영상유도 Co-60 기반 방사선치료기기의 커미셔닝 경험 (Commissioning Experience of Tri-Cobalt-60 MRI-guided Radiation Therapy System)

  • 박종민;박소연;우홍균;김정인
    • 한국의학물리학회지:의학물리
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    • 제26권4호
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    • pp.193-200
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    • 2015
  • 본 연구는 뷰레이 시스템의 커미셔닝 결과에 대한 보고이다. 먼저, 시스템 안전장치의 적절한 작동을 확인했다. 영상시스템에 대한 평가를 위해 신호 대 잡음비와 영상의 균질도, 공간적 무결성을 확인했다. 카우치 동작의 정확성 및 축교점의 일치성을 평가했다. 미국의학물리학회 특별업무단51규약 프로토콜에 따라 절대선량을 측정했다. BJR supplement 25에서 제공하는 심부선량백분율과 측정한 값의 차이, 치료계획에서 계산한 값과 측정한 심부선량백분율의 차이를 확인했다. 더불어, 출력인수에 대하여, 측정값과 계산값의 차이를 구했다. 최종 검증 단계로, 8개의 세기변조방사선치료계획을 사용하여 감마평가를 수행하였다. 커미셔닝을 수행한 결과, 모든 안전장치는 적절히 구동함을 확인했다. 신호 대 잡음비 값과 영상 균질도 값은 허용범위 이내임을 확인했다. 공간적 무결성 확인 결과, 반지름 10 cm 및 17.5 cm 안의 모든 지점에 대하여 각각 1 mm 및 2 mm 이내의 오차를 확인했다. 카우치는 x, y, z 방향으로 각각 0.2 mm, 0.1 mm, 0.2 mm의 오차를 보였다. 방사선 축교점과 가상 축교점 사이에는 x, y, z 방향으로 0 mm, 0 mm, 0.3 mm의 오차를 보였다. 영상 시스템의 축교점과 가상 축교점 사이에는 0.6 mm, 0.5 mm, 0.2 mm의 오차를 보였다. 다엽콜리메이터의 평균적 구동 오차는 0.6 mm였다. 측정한 출력의 오차는 0.5% 이내, 심부선량백분율 오차는 1% 이내, 출력인수 오차는 2% 이내였다. 세기조절방사선치료 감마평가 결과값이 $99.9%{\pm}0.1%$였다.

O2/SF6, O2/N2와 O2/CH4 플라즈마를 이용한 폴리카보네이트 건식 식각 (Dry etching of polycarbonate using O2/SF6, O2/N2 and O2/CH4 plasmas)

  • 주영우;박연현;노호섭;김재권;이성현;조관식;송한정;전민현;이제원
    • 한국진공학회지
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    • 제17권1호
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    • pp.16-22
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    • 2008
  • [ $O_2/SF_6$ ], $O_2/N_2$ 그리고 $O_2/CH_4$의 혼합 가스를 이용하여 폴리카보네이트의 플라즈마 식각을 연구하였다. 플라즈마 식각 장비는 축전 결합형 플라즈마 시스템을 사용하였다. 폴리카보네이트 식각은 감광제 도포 후에 UV 조사의 포토리소그래피 방법으로 마스크를 제작하여 실험하였다. 본 식각 실험에서는 $O_2$와 다른 기체와의 혼합비와 RIE 척 파워 증가에 따른 폴리카보네이트의 식각 특성 연구를 중심으로 하였다. 특히 건식 식각 시에 사용한 공정 압력은 100 mTorr로 유지하였으며 공정 압력은 기계적 펌프만을 사용하여 유지하였다. 식각 실험 후에 표면 단차 측정기, 원자력간 현미경 그리고 전자 현미경 등을 이용하여 식각한 샘플을 분석 하였다. 실험 결과에 의하면 폴리카보네이트 식각에서 $O_2/SF_6$의 혼합 가스를 사용하면 순수한 $O_2$$SF_6$를 사용한 것보다 각각 약 140 % 와 280 % 정도의 높은 식각 속도를 얻을 수 있었다. 즉, 100 W RIE 척 파워와 100 mTorr 공정 압력을 유지하면서 20 sccm $O_2$의 플라즈마 식각에서는 약 $0.4{\mu}m$/min, 20 sccm의 $SF_6$를 사용하였을 때에는 약 $0.2{\mu}$/min의 식각 속도를 얻었다. 그러나 60 %의 $O_2$와 40 %의 $SF_6$로 혼합된 플라즈마 분위기에서는 20 sccm의 순수한 $O_2$에 비해 상대적으로 낮은 -DC 바이어스가 인가되었음에도 식각 속도가 약 $0.56{\mu}m$/min으로 증가하였다. 그러나 $SF_6$ 양의 추가적인 증가는 폴리카보네이트의 식각 속도를 감소시켰다. $O_2/N_2$$O_2/CH_4$의 플라즈마 식각에서는 $N_2$$CH_4$의 양이 각각 증가함에 따라 식각 속도가 감소하였다. 즉, $O_2$$N_2$$CH_4$의 혼합은 폴리카보네이트의 식각 속도를 저하시켰다. 식각된 폴리카보네이트의 표면 거칠기 절대값은 식각 전에 비해 $2{\sim}3$ 배정도 증가하였지만 전자현미경으로 표면을 관찰 하였을 때에는 식각 실험 후의 폴리카보네이트의 표면이 깨끗한 것을 확인할 수 있었다. RIE 척 파워의 증가는 -DC 바이어스와 폴리카보네이트의 식각 속도를 거의 선형적으로 증가시켰으며 이 때 폴리카보네이트의 감광제에 대한 식각 선택비는 약 1:1 정도였다. 본 연구의 의미는 기계적 펌핑 시스템만을 사용한 간단한 플라즈마 식각 시스템으로도 $O_2/SF_6$의 혼합 가스를 사용하면 폴리카보네이트의 미세 구조를 만드는데 사용이 가능하며 $O_2/N_2$$O_2/CH_4$의 결과에 비해 상대적으로 우수한 식각 조건을 얻을 수 있었다는 것이다. 이 결과는 다른 폴리머 소재 미세 가공에도 응용이 가능하여 앞으로 많이 사용될 수 있을 것으로 예상한다.

Relationships of Circulating Concentrations of Insulin-like Growth Factor (IGF)-I and -II to Egg Production and Growth Rate in the Korean Native Ogol Chicken

  • Yun, J.S.;Kang, W.J.;Seo, D.S.;Lee, C.Y.;Oh, S.;Ko, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제16권4호
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    • pp.481-488
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    • 2003
  • Insulin-like Growth Factors (IGFs) and IGF-binding protein act as intra-ovarian regulators that modulate the proliferation and differentiation of the granulosa and theca cells. Moreover, the IGF system is involved in metabolism by modulating the synthesis and degradation of glycogen and protein in animals. However the effect of the IGF system on egg productivity or body growth in KNOC has not been studied in depth. Therefore, this study was performed to investigate differences of serum IGFs and binding protein expressions between two groups showing high and low egg production or body weight and to elucidate the relationship of IGFs with egg productivity and body growth. KNOCs were divided into high and low groups depending on their egg productivity or body growth, and sera were collected every 10 wk from 20 till 60 wk. Serum IGF-I and -II concentration were measured by RIA using human and mouse antiserum and chicken standards. IGFBP was detected by Western ligand blotting. IGF-I concentrations were significantly greater in the high egg production group compared with those in the low egg production group (30 wk, p<0.01; 20 and 40 wk, p<0.05). Also, differences in IGF-II amounts between the two groups were detected at 60 wk (p<0.05). But IGFBPs in the low egg production group were more intense than that in the high egg production group through the egg laying period. The correlation between IGF-I concentration and number of egg production is significantly positive (20 wk, r=0.2729: p<0.05; 40 wk, r=0.3500: p<0.01), while IGF-II shows no correlation with egg productivity. In male KNOC, IGF-I and -II concentrations in the high body weight group are lower than that in the low body weight group. Body weight also shows a negative correlation with the serum IGF-II concentration in male chickens (20 wk, r=-0.5901: p<0.01). Consequently, we suggest that IGFs and binding protein are (in)directly involved in the egg productivity and body growth in KNOC.

Effects of Dietary Garlic Extracts on Whole Body Amino Acid and Fatty Acid Composition, Muscle Free Amino Acid Profiles and Blood Plasma Changes in Juvenile Sterlet Sturgeon, Acipenser ruthenus

  • Lee, Dong-Hoon;Lim, Seong-Ryul;Ra, Chang-Six;Kim, Jeong-Dae
    • Asian-Australasian Journal of Animal Sciences
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    • 제25권10호
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    • pp.1419-1429
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    • 2012
  • A series of studies were carried out to investigate the supplemental effects of dietary garlic extracts (GE) on whole body amino acids, whole body and muscle free amino acids, fatty acid composition and blood plasma changes in 6 month old juvenile sterlet sturgeon (Acipenser ruthenus). In the first experiment, fish with an average body weight of 59.6 g were randomly allotted to each of 10 tanks (two groups of five replicates, 20 fish/tank) and fed diets with (0.5%) or without (control) GE respectively, at the level of 2% of fish body weight per day for 5 wks. Whole body amino acid composition between the GE and control groups were not different (p>0.05). Among free amino acids in muscle, L-glutamic acid, L-alanine, L-valine, L-leucine and L-phenylalanine were significantly (p<0.05) higher in GE than in control. However, total whole body free amino acids were significantly lower in GE than in control (p<0.05). GE group showed higher EPA (C22:6n3) and DHA (C22:5n3) in their whole body than the other group (p<0.05). In the second experiment, the effects of dietary garlic extracts on blood plasma changes were investigated using 6 month old juvenile sterlet sturgeon averaging 56.5 g. Fish were randomly allotted to each of 2 tanks (300 fish/tank) and fed diets with (0.5%) or without (control) GE respectively, at the rate of 2% of body weight per day for 23 d. At the end of the feeding trial, blood was taken from the tail vein (n = 5, per group) at 1, 12, and 24 h after feeding, respectively. Blood plasma glucose, insulin and the other serological characteristics were also measured to assess postprandial status of the fish. Plasma glucose concentrations (mg/dl) between two groups (GE vs control) were significantly (p< 0.05) different at 1 (50.8 vs 62.4) and 24 h (57.6 vs 73.6) after feeding, respectively, while no significant difference (p>0.05) were noticed at 12 h (74.6 vs 73.0). Plasma insulin concentrations (${\mu}IU$/ml) between the two groups were significantly (p<0.05) different at 1 (10.56 vs 5.06) and 24 h (32.56 vs 2.96) after feeding. The present results suggested that dietary garlic extracts could increase dietary glucose utilization through the insulin secretion, which result in improved fish body quality and feed utilization by juvenile sterlet sturgeon.

선박충돌 위기상황에서 선박운항자가 지각한 충돌위험도 분석 (Analysis of Collision Risk Perceived by Ship Operators in Ship Collision Risk Situation)

  • 김대식;임정빈
    • 대한인간공학회지
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    • 제36권5호
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    • pp.447-458
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    • 2017
  • Objective: The purpose of this study is to present the basic guidelines for preventing human error by measuring and analyzing the risk of collision perceived by the ship operator in the collision risk situation by using Korea Coast Guard patrol ships. Background: In the last 5 years, 97.5% of the causes of ship collision occurred at the sea was caused by human factors. However, the rate of marine accidents due to human error has not been reduced yet. Experiments and researches on the ship operators using the ships in actual operation are rarely performed. Method: Using two K.C.G Ships on the sea, the ship measured by 30 persons who are the subject of the ship (ship operator) when both ships approach and the relative distance gradually decreases in four encounter situations, perceived ship collision risk (PSCR) data were analyzed by statistical analysis. Results: The age and boarding career of the ship operator in the situation of ship collision risks encountered a negative impact on perceived collision risk in all four opposing encounter situations S1 ($000^{\circ}$), S2 ($045^{\circ}$), S3 ($090^{\circ}$) and S4 ($135^{\circ}$) respectively. That is, the higher the age of the ship operator, the lower the perceived risk of collision and the lower the age, the higher the risk of collision. Also, there was a difference between the average of group A (20~30 years) and group B (40~50 years) according to age of the ship operators at $000^{\circ}$, $045^{\circ}$ and $090^{\circ}$ and there was no difference at $135^{\circ}$. The mean difference of the experience of boarding career was also significantly different between group A (less than 4 years) and group B (more than 5 years), but there was no significant difference at $135^{\circ}$. Conclusion: The results showed that age and boarding career of the ship operators had negative impact on perceived collision risk and there was a difference in perceived risk of collision according to age and abundance of boarding career. As a result, by focusing on the ship operators who are in the age group of 20~30 years old and have less than 4 years of experience in boarding the ship. It is expected that the effect of prevention of marine accidents can be expected by avoiding collision avoidance. Application: The results of this study can be used as policy data of related organizations to prevent human error of ship operators and as training data of training institutes.

폐승격(肺勝格) 자침이 촌관척(寸關尺) 맥파변화에 미치는 영향 (The Effect of $Sa-Am$ Lung Sedating Acupuncture on Wrist Pulse in Healthy Human Subjects)

  • 김석주;이현
    • Journal of Acupuncture Research
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    • 제29권2호
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    • pp.43-57
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    • 2012
  • Objectives : The purpose of this study is to observe the effects of $Sa-Am$ lung sedating acupuncture (LS) on wrist pulse changes in healthy participants. Method : Forty healthy subjects participated in this study, and were divided into an acupuncture group and controlled group. Using a three-dimensional pulse imaging system (DMP-3000), wrist pulse was measured before, immediately after, 30 minutes after and 60 minutes after acupuncture in the acupuncture group, with the rest in controlled group. Sixteen parameters between the acupuncture group and the controlled group were analyzed at Cun, Guan and Chi in each time. Result : After LS acupuncture, wrist pulse sixteen parameters were changed significantly according to the time at each measuring region. 1. Heart rate significantly decreased in immediately after, 30 minutes after and 60 minutes after, Pulse period significantly increased in 30 minutes after and 60 minutes after. 2. T4 didn't significantly changed, T-T4 significantly increased in immediately after, 30 minutes after and 60 minutes after. T4/T, T4/(T-T4), T1/T, T5/T significantly decreased in immediately after, 30 minutes after and 60 minutes after. (T-T4)/T significantly decreased in immediately after, 30 minutes after and 60 minutes after. T5 significantly increased in 30 minutes after and 60 minutes after. 3. Modulus of elasticity significantly decreased in left Cun 60 minutes after, significantly increased in left Chi 30 minutes after. 4. Variance of Amplitude significantly increased in right Guan 60 minutes after. 5. Area of pulse significantly increased in left Cun 60 minutes after, left Chi 30 minutes after and right Cun 60 minutes after. Systolic pulse area significantly decreased left Chi 30 minutes after, right Cun immediately after, 30 minutes after and 60 minutes after, right Guan in immediately after. 6. Energy/min significantly decreased in left Chi 60 minutes after and right Cun immediately after. EIx significantly decreased in right Cun immediately after. 7. In both sides Cun, Guan, Chi wrist pulse, a lot of significant changes in right Cun and left Chi appeared, and then followed by the left Cun, right Guan. Conclusion : This study analyzed that the correlation between LS acupuncture and radial pulse(cun, guan, chi) is considered to be meaningful, hereafter clinical studies on this are needed.

아크릴계 이온교환섬유를 이용한 수중 크롬(VI) 제거 (Chromium(VI) Removal from Aqueous Solution using Acrylic Ion Exchange Fiber)

  • 남아름;박정안;도태구;최재우;최웅수;김경남;윤성택;이상협
    • 대한환경공학회지
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    • 제39권3호
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    • pp.112-117
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    • 2017
  • PAN 기반 아크릴계 섬유와 DETA 및 $AlCl_3{\cdot}6H_2O$를 반응시켜 아민기($-NH_2$)를 가진 이온교환섬유 PADD를 합성하였다. 개발된 섬유상 소재는 FT-IR과 SEM을 이용하여 그 특성을 확인해 보았다. 회분식 실험으로 수행된 PADD를 이용한 크롬제거 실험 결과는 Langmuir 등온흡착모델에 잘 적용되었으며, 이때 계산된 이론적 최대흡착능 ($Q_{max}$)은 6.93 mmol/g으로 나타났다. 한편 동적흡착실험은 Lagergren 유사이차속도모델에 잘 부합되었다. PADD의 크롬 흡착능은 pH 2에서 가장 높은 값인 4.11 mmol/g을 나타내었고 pH 변화에 많은 영향을 받는 것으로 확인되었다. 또한, 인산과 비소(V)에 대한 공존이온 실험을 통해 PADD가 크롬에 대한 높은 선택성을 갖고 있음을 확인할 수 있었다. 산-염기 역적정으로 구한 PADD의 총이온교환능 (4.70 mmol/g)을 통해 소재의 선택적 제거 가능성을 검증하였다.

정압주입시험을 이용한 지하수유동차원 해석 (Flow Dimensional Analysis for Constant Pressure Injection Test)

  • 이은용
    • 지질공학
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    • 제3권2호
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    • pp.149-165
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    • 1993
  • 지하매질의 유동특성을 알기 위한 직접적인 방법은 아직도 현장수리시험에 의존하고 있다. 열극암반에서 유동모델의 개념정립을 위하여는 열극체계분포와 특히, 수리시험해석결과가 중요시되고 있다. 국내에서 수행되고 있는 수리시험은 조사공구간별에 따른 수리전도도를 방사상의 정상류로 가정하여 결과를 해석하고 있다. 또한 시험대상 매질을 균질한 대수층 또는 단순한 기하학적 형태의 매질로 간주하며 구간별 투수량계수는 시험구간을 가로지르는 각 열극의 투수량계수의 합과 같다고 가정한다. 국내 기존의 수리시험 및 해석방법으로는 수리학적 경계면의 영향(boundary effects)이나 유동로의 기하학적 형태(flow geometry)에 대한 자료를 얻기가 힘들며, 일정한 조사공 주변을 벗어나면 투수성열극의 연결성에 대한 정보를 구할 수 없다. 열극특성을 고려한 지하수유동 해석을 위하여 단일공 정압주입시험을 실시하였으며, 비정상류해석방법을 통하여 유동차원(flow dimension)에 대한 분석을 시도하였다. 시추시에는 단일패커시험을 일정구간별로 시행하였으며, 조사공의 시추후에는 이중패커에 의한 구간별 시험을 실시하였다. 비정상류해석으로 구한 수리전도도값은 정상류해석의 결과와 큰 차이(10배 이내)는 없었으나, 정압하에서 도출된 유동량변화곡선에서 유동차원분석이 가능하였다. 상부구간(<10m 깊이)의 단일 및 이중패커시험결과는 모두 정상류의 유동차원이 나타났으며, 이는 영향반경의 경계면이 open system임을 알 수 있다. 15m 깊이에서 도출된 유동량변화곡선은 1차원 유동상태에서 3차원(구상유동)으로 변화하였다. 하부구간(25m 깊이)의 시험결과는 closed system 특성이 관찰되었으며, 이는 조사구간에서 연결된 열극이 수리적으로 격리되어 있음을 알 수 있다. 현장수리시험으로부터 보다 많은 자료를 도출하기 위하여는 무엇보다도 수리시험장비의 보완이 필요하다. 특히 조사구간을 완벽하게 분리할 수 있는 패커장비와 미세한 유동량변화를 계측할 수 있는 유량계의 확보가 필수적이며, 조사구간의 압력변화를 자동기록할 수 있는 계측기기가 필요하였다.

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지하 수위가 다른 조건에서 콩의 초장과 경태 모델링 (Modeling Growth of Canopy Heights and Stem Diameters in Soybeans at Different Groundwater Level)

  • 최진영;김동현;권순홍;최원식;김종순
    • 한국산업융합학회 논문집
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    • 제20권5호
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    • pp.395-404
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    • 2017
  • Cultivating soybeans in rice paddy field reduces labor costs and increases the yield. Soybeans, however, are highly susceptible to excessive soil water in paddy field. Controlled drainage system can adjust groundwater level (GWL) and control soil moisture content, resulting in improvement soil environments for optimum crop growth. The objective of this study was to fit the soybean growth data (canopy height and stem diameter) using Gompertz model and Logistic model at different GWL and validate those models. The soybean, Daewon cultivar, was grown on the lysimeters controlled GWL (20cm and 40cm). The soil textures were silt loam and sandy loam. The canopy height and stem diameter were measured from the 20th days after seeding until harvest. The Gompertz and Logistic models were fitted with the growth data and each growth rate and maximum growth value was estimated. At the canopy height, the $R_2$ and RMSE were 0.99 and 1.58 in Gompertz model and 0.99 and 1.33 in Logistic model, respectively. The large discrepancy was shown in full maturity stage (R8), where plants have shed substantial amount of leaves. Regardless of soil texture, the maximum growth values at 40cm GWL were greater than the value at 20cm GWL. The growth rates were larger at silt loam. At the stem diameter, the $R_2$ and RMSE were 0.96 and 0.27 in Gompertz model and 0.96 and 0.26 in Logistic model, respectively. Unlike the canopy height, the stem diameter in R8 stage didn't decrease significantly. At both GWLs, the maximum growth values and the growth rates at silt loam were all larger than the values at sandy loam. In conclusion, Gompertz model and Logistic model both well fit the canopy heights and stem diameters of soybeans. These growth models can provide invaluable information for the development of precision water management system.

성대폴립, 성대낭종 환자들의 Laryngeal Micro Surgery 수술 전, 후 공기역학적 비교: Running Speech 중심으로 (Aerodynamic Characteristics of Voice Disorders (Polyp, Cyst) before and after Laryngeal Micro Surgery: Focus on Running Speech)

  • 문태훈;심미란;황연신;김근전;이동현;선동일
    • 대한후두음성언어의학회지
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    • 제30권2호
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    • pp.95-100
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    • 2019
  • Background and Objectives For patients with polyps and cysts, glottal gaps resulting from their lesions have negative respiratory effects when they vocalize. Phonatory Aerodynamic System is clinically used, but is often limited in the measurement of vowels. So the researchers attempted to verify the usefulness of Phonatory Aerodynamic System by comparing differences in respiratory characteristics and patterns which can be measured by the level of connected speech. Materials and Method Among the subjects who were diagnosed through a stroboscopy, there were 33 patients with polyps and 23 patients with cysts. Then, 36 subjects who were found to have no specific findings through a stroboscopy and perceptual test were selected to the normal group. We compared respiratory characteristics and patterns. And compared vocal polyps and cysts before and after laryngeal micro surgery (LMS). Results First, difference in respiratory patterns between the normal group and the patients with polyps and cysts were examined to show that breath groups, breath group syllables, and expiratory·inspiratory volume were significantly higher in the polyp/cyst group than those in the normal group, indicating that precision was lowered during the conversation, due to reduction in speech intelligibility and interruption of communication. Second, there were significant differences in maximum phonation time, mean flow rate, and subglottal pressure among respiratory characteristics, breath groups, breath group syllables, and inspiratory volume before and after LMS, which appeared to be similar to the normal group. Conclusion The understanding of respiratory characteristics and patterns produced by patients in connected speech which is most similar to natural speech was found to be the objective and useful method for examining characteristics of the subjects.