• Biomolecules & Therapeutics
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• 제10권4호
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• pp.281-286
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• 2002

In this study, we intended to get a preliminary data for establishing rat tracheal surface epithelial(RTSE) cell culture system as an experimental model for physiology and pharmacology of tracheal epithelial cells. Primary culture on the membrane support and application of the air-liquid interface system at the level of cell layer were performed. The cell growth rate and mucin production rate were measured according to the days in culture. The results were as follows: this culture system was found to manifest mucocilliary differentiation of rat tracheal epithelial cells, the cells were confluent and the quantity of produced and released mucin was highest on culture day 9, the mucin was mainly released to the apical side and tbe free $^3{H}$-glucosamine which was not incorporated to process of synthesis of mucin was left on the basolateral side. Taken together, we suggest that air-liquid interface culture system can be used as a substitute for immersion culture system and as an experimental model for in vivo mucus-hypersecretory diseases.

• 통합자연과학논문집
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• 제14권3호
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• pp.95-98
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• 2021

By far, studies on the effect of oral administration of peppermint essential oil on blood pressure are not consistent, increasing or decreasing. And the effect of inhalation of peppermint essential oil on blood pressure was not reported. This study was designed to clarify the effect of peppermint essential oil inhalation on the blood pressure and autonomic nervous system. Blood pressure and heart rate variability (HRV) as an indicator of autonomic nervous system activity were measured. The systolic and diastolic blood pressure was not changed significantly by inhalation of peppermint essential oil. Standard deviation of normal to normal (SDNN), a parameter of total activity of autonomic nervous system also was not changed significantly. High frequency (HF) power level, an indicator of parasympathetic nervous system activity was not changed by peppermint. These results indicate that action mechanism of peppermint essential oil on blood pressure is different by the method of administration, oral or inhalation.

• 대한물리치료과학회지
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• 제26권2호
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• pp.32-37
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• 2019

Background: The purpose of this study is to investigate the change of blood pressure and autonomic neural system through one-time bamboo stepping in hypertensive elderly people. Design: Randomized Controlled Trial. Methods: We recruited 26 elderly people aged 65 or older for study. They sat for 10 minutes in a chair, rested, and measured pre-exercise blood pressure and autonomic neural system. The blood pressure was measured three times and the mean value was used and the autonomic neural system was measured once. Bamboo stepping exercise was performed for 20 minutes. Blood pressure and autonomic neural system were measured 5 times immediately after exercise, and every 15 minutes at 60 minutes after bamboo stepping exercise. Results: There was a significant difference in the decrease of systolic blood pressure after one-time bamboo stepping exercise, the change of parasympathetic activity (HF), heart rate variability (HRV) and BPM measured immediately after exercise at 15 minutes after exercise, There was no significant difference in autonomic neural system change. Conclusion: One-time Bamboo stepping exercise is effective in decreasing systolic blood pressure of the hypertensive elderly.

• Applied Microscopy
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• 제17권2호
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• pp.55-71
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• 1987

To investigate the effects of lead on the electron transport system and ultrastructure of mouse kidney mitochondria, various lead acetate concentrations were treated in vitro and respiration rate, enzyme activities were measured. Ultrastructural changes at state IV respiration were also observed. To compare with in vivo experiments, mouse were injected intraperitoneally of 100 mg lead acetate per kg body weight and state IV respiration rate and enzyme activities were measured. Ultrastructure of renal proximal tubular cells were also observed. In in vitro treatement, decreased state IV respiration, decreased enzyme activities, ruptured membranes and inhibition of condensed to orthodox transformation were observed. In in vivo treatment, decreased state IV respiration and decreased enzyme activities were observed after 24 hrs of i.p. injection. Cytochrome c oxidase activity showed twice the inhibition compared to NADH-CoQ reductase activity at 24 hrs. Continuous decreased state IV respiration was observed after 48 and 72 hrs of injection, however, the enzyme activities were increased to control level. Lead-protein complex which probably inhibits the toxic effects of lead appeared. To conclude, dominant effect of lead on the electron transport system appeared at cytochrome c oxidase activity, and the increased enzyme activities may be a result of appearance of lead-protein complex.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
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• pp.407-408
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• 2006

Passenger safety is one of the most important considerations in the purchase of an automobile. A curtain-type air bag is increasingly adapted in deluxe cars for protecting passengers from the danger of side clash. Inflator housing is a main part of the curtain-type air bag system for supplying high-pressure gases to pump up the air bag-curtain. Although the inflator housing is fundamental in designing a curtain-type air bag system, flow information on the inflator housing is very limited. In this study, we measured instantaneous velocity fields of a high-speed flow ejecting from the inflator housing using a dynamic PIV system. From the velocity field data measured at a high frame-rate, we evaluated the variation of the mass flow rate with time. From the instantaneous velocity fields of flow ejecting from the airbag inflator housing in the initial stage, we can see a flow pattern of broken shock wave front and its downward propagation. The flow ejecting from the inflator housing was found to have large velocity fluctuations and the maximum velocity was about 700m/s. The velocity of high-speed flow was decreased rapidly and the duration of high-speed flow over 400m/s was maintained only to 30ms. After 100ms, there was no perceptible flow.

• 융합신호처리학회논문지
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• 제12권3호
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• pp.157-162
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• 2011

본 연구는 심폐소생술 (CPR) 중 인공호흡의 무선 전송 시스템 구현에 관한 것으로, 병원 전 단계에서의 CPR 성과를 높임으로써 응급환자의 생존율을 높이기 위한 환자-병원간 무선 통신 시스템이다. 기도삽관 기반 호흡기류센서를 적용하여 호흡량을 측정하였는데, 기도삽관을 통한 인공호흡은 기류량의 손실을 최소화하여 보다 정확한 흡기-호기량 계측이 가능하고, 기도-식도 구분을 통해 식도팽창을 방지하여 다른 인공호흡 방법에 비해 장점을 입증하였다. 또, 인공호흡 주요지표인 분당 평균호흡량 (V), 호기말 이산화탄소 농도 ($EtCO_2$), 기도압력 (Ptr)을 디지털화하여 정의하였으며 정의된 데이터를 무선 통신 시스템을 이용하여 전송망의 대역폭 및 지연시간을 확인하였다. 호흡신호를 전송하기 위해 필요한 최대대역폭 (815 Kbps) 에 비해 Wireless LAN의 대역폭 (54 Mbps) 이 충분하여 네트워크 부하는 1.5 % 미만이었으며, 전송지연시간은 0.3 초 이내로 측정되었다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 추계학술대회논문집B
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• pp.309-313
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• 2000

An experimental study was conducted to analyze the characteristics of the showcase refrigeration system during frosting and defrosting process. Test showcase was constructed with a cooling capacity of 3RT including 3 evaporators. The dynamic characteristics of the system under frosting and defrosting conditions were investigated. Refrigerant temperature and pressure of the system, dry bulb and wet bulb temperature of air passing through the evaporator, air flow rate and compressor power were measured.

• Journal of Biosystems Engineering
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• 제26권3호
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• pp.271-278
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• 2001

Many workers in the garlic peeling factory are separating the sound peeled garlics from the unpeeled and defective ones in a manual way. In order to reduce the seasonal labor requirement and operating cost, the mechanized garlic sorting system such as the vision-based garlic sorter should be developed. This study was conducted as one of basic studies on developing quality evaluation technique for peeled garlics, especially to developed the system for acquiring the whole surface images of garlics with a CCD camera. The following results were obtained from this study. 1. The belt-type garlic rotation system was devised to apply for the vision-based garlic sorter and was tested to decide the criteria of design and optimum conveying speed. 2. To evaluate the performance of the developed garlic rotation system, feeding rate and rotating rate were measured under the conditions of four experimental factors such as the inclined angle of rotating belt, the inclined angle of feeding belt, the height of plate arrays on feeding belt and the conveying speed of belts. And the capacity of the system according to mixture ratios of peeled garlics and unpeeled garlics was analyzed as a feasibility test. 3. For the inclined angle of rotating belt 20°and height of plate array on feeding belt 22㎜, the maximum rotating rate for garlic samples including unpeeled ones was 81.1% at the conveying speed of 4.2 garlic/sec. And under these condition, the maximum feeding rate was 85% at the inclined angle of feeding belt 6.5°. 4. The capacity of the developed garlic rotation system was almost constant regardless of mixture ratio of peeled garlics and unpeeled garlics and its range was 2.95∼3.92 garlic/sec. At the conveying speed of 4.2 garlic/sec, the capacity of the garlic rotation system was calculated ad 58∼64 kg/hr. 5. To improve performance of the garlic rotation system, it is recommended to develop a device to slide garlics into feeding belt.

• 디지털융복합연구
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• 제11권6호
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• pp.137-142
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• 2013

음성 인식 시스템은 부정확한 음성 신호의 입력으로 특징을 추출하여 인식할 경우 오인식의 결과가 나타나거나 유사한 음소로 인식된다. 따라서 본 논문에서는 음소가 갖는 특징을 기반으로 음소 유사율과 신뢰도 측정을 이용한 음성 인식 오류 보정 방법을 제안하였다. 음소 유사율은 학습 모델의 음소에 MFCC와 LPC 특징 추출 방법을 이용하여 구하였으며 신뢰도로 측정하였다. 음소 유사율과 신뢰도를 측정하여 오인식되는 오류를 최소화하였으며 음성 인식 과정에서 오류로 판명된 음성에 대하여 오류 보정을 수행하였다. 본 논문에서 제안한 시스템을 적용한 결과 98.3%의 인식률과 95.5%의 오류 보정율을 나타내었다.

• 한국전기전자재료학회논문지
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• 제29권5호
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• pp.284-288
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• 2016

Among the various physiological information that could be obtained from human body, heartbeat rate is a commonly used vital sign in the clinical milieu. Photoplethysography (PPG) sensor is incorporated into many wearable healthcare devices because of its advantages such as simplicity of hardware structure and low-cost. However, healthcare device employing PPG sensor has been issued in susceptibility of light and motion artifact. In this paper, to develop the real-time heart rate measurement device that is less sensitive to the external noises, we have fabricated an ultra-small wireless LC resonant pressure sensor by MEMS process. After performance evaluation in linearity and repeatability of the MEMS pressure sensor, heartbeat waveform and rate on radial artery were obtained by using resonant frequency-pressure conversion method. The measured data using the proposed heartbeat rate measurement system was validated by comparing it with the data of an commercialized heart rate measurement device. Result of the proposed device was agreed well to that of the commercialized device. The obtained real time heartbeat wave and rate were displayed on personal mobile system by bluetooth communication.