• 제목/요약/키워드: Mean Residual Life

검색결과 123건 처리시간 0.033초

딸기의 세척 및 가공 과정에 따른 농약 잔류량 변화 (Variation of Pesticide Residues in Strawberries by Washing and Boiling Processes)

  • 곽세연;이상협;정혜린;남애지;;김효영;임채욱;조현정;김장억
    • 한국환경농학회지
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    • 제38권4호
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    • pp.281-290
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    • 2019
  • 안전한 딸기 섭취를 위해 딸기에 acetamiprid외 9종의 농약을 인위적으로 살포하여 건조시킨 후 물, 세제, 소주에 침지 및 초음파 세척하였을 경우와 가열하여 잼으로 가공하였을 때 잔류량 변화 및 가공계수를 산출하였다. 농약이 처리된 딸기를 세척 및 가공하였을 때 물에 침지하여 세척한 경우 13.9-65.1%, 세제에 침지한 경우 9.2-71.9%, 소주에 침지한 경우 12.4-61.6%, 물로 초음파 세척한 경우 22.4-62.8%, 세제로 초음파 세척한 경우 18.7-64.5%, 소주로 초음파 세척한 경우 23.1-64.4% 감소하였다. 딸기 중 잔류농약의 제거율은 농약에 따라서 다르게 나타났으나, 세척 용매 및 방법에 따라 큰 차이를 보이지 않았기 때문에 물로 세척하는 것이 가장 효율적이며 세척 횟수를 늘리는 것이 보다 효과적인 방법으로 생각되었다. 가공함에 따라 딸기의 생체량이 2.5배 감소하는 것을 반영하여 가공 전과 후의 절대량을 산출한 결과, 10종의 시험 농약 모두 59.8-98.4%감소하는 경향을 보였다.

A software reliability model with a Burr Type III fault detection rate function

  • Song, Kwang Yoon;Chang, In Hong;Choi, Min Su
    • International Journal of Reliability and Applications
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    • 제17권2호
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    • pp.149-158
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    • 2016
  • We are enjoying a very comfortable life thanks to modern civilization, however, comfort is not guaranteed to us. Development of software system is a difficult and complex process. Therefore, the main focus of software development is on improving the reliability and stability of a software system. We have become aware of the importance of developing software reliability models and have begun to develop software reliability models. NHPP software reliability models have been developed through the fault intensity rate function and the mean value functions within a controlled testing environment to estimate reliability metrics such as the number of residual faults, failure rate, and reliability of the software. In this paper, we present a new NHPP software reliability model with Burr Type III fault detection rate, and present the goodness-of-fit of the fault detection rate software reliability model and other NHPP models based on two datasets of software testing data. The results show that the proposed model fits significantly better than other NHPP software reliability models.

Seismic evaluation of self-centering energy dissipating braces using fragility curves

  • Kharrazi, Hossein;Zahrai, Seyed Mehdi
    • Steel and Composite Structures
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    • 제37권6호
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    • pp.679-693
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    • 2020
  • This paper investigates the seismic response of buildings equipped with Self-Centering Energy Dissipating (SCED) braces. Two-dimensional models of 3, 6, 12 and 16-story SCED buildings considering both material and geometric nonlinearities are investigated by carrying out pushover and nonlinear time-history analyses. The response indicators of the buildings are studied for weight-scaled ground motions to represent the Design Basis Earthquake (DBE) level and the Maximum Considered Earthquake (MCE) event. The fragility curves of the buildings for two Immediate Occupancy (IO) and Life Safety (LS) performance levels are developed using Incremental Dynamic Analysis (IDA). Results of the nonlinear response history analyses indicate that the maximum inter-story drift occurs at the taller buildings. The mean peak inter-story drift is less than 2% in both hazard levels. High floor acceleration peaks are observed in all the SCED frames regardless of the building height. The overall ductility and ductility demand increase when the number of stories reduces. The results also showed the residual displacement is negligible for all of case study buildings. The 3 and 6-story buildings exhibit desirable performance in IO and LS performance levels according to fragility curves results, while 12 and 16-story frames show poor performance especially in IO level. The results indicated the SCED braces performance is generally better in lower-rise buildings.

돼지와 랫트에서 sulfamethazine의 약물동태학 및 조직분포 (Pharmacokinetic profile and tissue distribution of sulfamethazine in pigs and rats)

  • 윤효인;박승춘;오태광;조준형;박종명
    • 대한수의학회지
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    • 제37권2호
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    • pp.291-299
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    • 1997
  • In order to establish optimal dosage schedules and withdrawal times for sulfamethazine(SMZ) in pigs, pharmacokinetic and tissue distribution experiments were conducted in pigs. For comparative purposes, tissue depletion kinetics are also studied in rats. From three pigs administered with SMZ i.v., the pharmacokinetic profile of SMZ in two pigs was adequately described by a one-compartment open model whereas that in one pig was patterned after a two-compartment open model. Volume of distribution(Vd) was 0.48~0.57 L/kg and biological half-life($t_{1/2}$) was 11.8-16.8 h. From three pigs dosed with SMZ p.o., pharmacokinetic profile was explainable with a one-compartment open model. Time to reach maximum SMZ concentration in serum (Tmax) was 2.8 h, 3.2 h and 7.5 h. Elimination half-life was 2.8-7.5 h. The descending order in concentration of SMZ was plsama > kidney > liver > lung > heart > pancreas > spleen > duodenum > ileum > brain > adipsoe tissue from three pigs sacrificed at 5h, 29h and 54h after the administration of SMZ, p.o.. The protein binding of SMZ in pigs was 55.2%($2.5{\mu}g/ml$), 71.5% ($5{\mu}g/kg$) and 71.5%($10{\mu}g/ml$). The mean systemic bioavailability (F) of SMZ p.o. was 49.1 %. Meanwhile the pharmacokinetic profile of SMZ in rats was adequately described by a one-compartment open model. Absorption of SMZ p.o. in the rat was very rapid. In conclusion, the oral optimal dosage regimen of SMZ for pigs was the initial dose of 45.7 mg/kg followed by the maintenance dose of 30.2 mg/kg for high specific pathogens to SMZ. The time to reach below the stipulated residual allowable concentration (0.1 ppm) was calculated 93 h after oral administration of 200 mg/kg recommended by manufactureres.

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뇌성마비 성인의 근골격계와 기능 실태 (Musculoskeletal and Functional Status of Adults with Cerebral Palsy)

  • Yoon Myung-ok;Kim Chung-sun
    • The Journal of Korean Physical Therapy
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    • 제17권1호
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    • pp.43-68
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    • 2005
  • The purpose of this study was to report the physical status of adult with cerebral palsy who live in local community areas including Seoul, Busan, Daegu in Republic of Korea at 2004. 202-individuals with cerebral palsy(140 male, 62 female; mean age 31.9 years; range 19 to 64 years) were surveyed. Measures included a 29-item self-reported health status measure focusing on musculoskeletal status and functional performances. Adult cerebral palsy required continuous management for musculoskeletal and ambulatory function through therapeutic approach. This survey is restricted to population who had cared in welfare center for cerebral palsy in local community, so it needs to investigate home-residual adults with cerebral palsy and the population in rural community. The results were as follows: 1. Participants reported that they had a limitation of a daily of life activity due to musculoskeletal pain($43\%$), there was significant differences between a limitation of a daily of life activity and the decreased ambulatory function(p<.05). 2. Thirty six point six percentile of participants had the decreased ADL function, it was significant related with the impaired body location(p<.05) 3. Thirty nine point one percentile of participants who can independently gait had the decreased ambulatory function, it was significant differences with the usage of ambulatory assistive devices(p<.05). 4. There was significant differences ambulatory function both the body region with impairment and a grade of disability(p<.05). 5. Sixteen point three percentile of participants could not ambulate any more, there was significant differences between a age and a point of time for non-ambulation(p<.05). 6. There was significant differences between ambulatory function and physical activity(p<.05).

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요실금환자의 골반근육운동에 따른 자아존중감과 배뇨증상에 관한 연구 (A Study on Self-Esteem and Urinary Symptoms in Women with Urinary Incontinence)

  • 이영희;김선아
    • 기본간호학회지
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    • 제9권3호
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    • pp.360-369
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    • 2002
  • Purpose: The purpose of this study was to help enhance the quality of life for women with urinary incontinence. Self-esteem, urinary symptoms, peak pressure and duration in seconds for vaginal contraction after pelvic muscles exercise were examined. Method: One-group pretest-posttest design was employed participants were 27 married women from G city. The instrument for this study were : the self-esteem scale developed by Rosenberg(1965). the Urinary Symptom Questionnaire, a subjective measurement of urinary incontinence, developed by Jackson et al.(1996) and the Perineometer used as an objective measurement of peak pressure and duration in seconds. Result: 1. Self-esteem showed significant improvement after the exercise (t=-3.832, p= .001). 2. Comparison of results before the pelvic muscles exercise and after showed that there was a statistically significant difference for several urinary symptoms including enuresis (t=2.833, p=.009), frequency of incontinence (t=2.964, p= .006), incontinence volume (t=2.280, p= .031), incontinence before getting to the restroom (t=3.035, p= .006), incontinence with no reason or feeling (t= 3.051, p= 005) burning sensation (t= 2.132, p=.043), and a sense of residual urine (t=2.267 p=.032). The mean scores showed improvement in the urinary symptoms of management of incontinence (M=$0.04{\pm}0.22$), daily frequency of incontinence management (M=$0.13{\pm}0.85$), urinary control (M=$0.15{\pm}0.86$), running to the restroom (M=$0.15{\pm}0.60$) incontinence caused by coughing or physical activities (M=$0.19{\pm}0.57$) and hesitancy (M=$0.07{\pm}0.55$). Overall urinary symptoms decreased significantly (t =3.073. p= .007). 3. Peak pressure showed an increase from a mean of $24.26{\pm}16.20mmHg$ before the exercise to a mean of $28.63{\pm} 17.79mmHg$ after (t=-2.399, p=.024). Duration in seconds also increased from a mean of $6.00{\pm}4.95sec$ to $9.15{\pm}5.83sec$ (t=-4.400, p= 000). Conclusion: These findings suggest that pelvic muscle exercise serves to decrease urinary problems, improve self-esteem and increase peak pressure and duration in seconds.

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비인강암종의 구제치료 (Salvage Treatment of Nasopharyngeal Carcinoma)

  • 최종욱;김용환;민헌기;최건;권희원
    • 대한두경부종양학회지
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    • 제12권1호
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    • pp.3-7
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    • 1996
  • Nasopharyngeal carcinoma(NPC) is a disease whose primary initial treatment is radiation. Results of radiation therapy in early stage disease is promising; however, in stage IV disease, the best reported five-year survival is only about 30%. In patients with post-radiation recurrent disease, radiation controls only a small portion of patients, as well as being associated with significant radiation injury. In this paper we discuss the use of salvage treatment modalities for post-radiation recurrence. A retrospective chart review and analysis of salvage treatment results were performed for 39 patients with recurrent post-radiation NPC and positive cervical lymph nodes during the period beginning 1985 until 1995. Mean age of these patients was 52.3$\pm$10.37 years and male: female ratio was 1.8 : 1. Twenty patients were treated with salvage treatment, and ten patients were treated by salvage chemotherapy. A total of nine patients underwent surgical salvage treatment, including neck dissection(6), transnasal laser surgery and booster radiotherapy(2), and primary surgery(1). Salvage treatment were effective in reducing patients' pain in twenty patients (51.3%) and prolonging life in nine patients(23.1%); however, recurrence of disease within six months and/or residual disease by clinical or radiologic exam was noted in all patients receiving salvage radiotherapy, chemotherapy, laser surgery with radiotherapy, and primary site surgery. In the group undergoing salvage neck dissection, three patients(50%) were disease free for at least two years. Of the different modalities, radiotherapy was associated with the best quality of life while catastrophic salvage surgery resulting in insignificant prolongation of life was associated with the poorest quality of life. We conclude that salvage surgery is the optimal choice of treatment for regional recurrence such as nodal failure, however palliative salvage therapy could be preferred in other cases with recurrent post-radiation NPC.

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Cadmium and Zinc Uptake Characteristics of Corn Plant in Arable Soil Contaminated by Smelting Factory Source

  • Hong, Chang-Oh;Gutierrez, Jessie;Oh, Ju-Hwan;Lee, Yong-Bok;Yu, Chan;Kim, Pil-Joo
    • 한국환경농학회지
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    • 제26권3호
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    • pp.210-216
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    • 2007
  • The cadmium (Cd) and zinc (Zn) contamination of soils and cultivated crop plants by zinc smelting activities was studied. In the study area of the vicinity of ${\triangle}{\triangle}$ zinc smelting factory in Korea, soils and corn plants were sampled at corn harvesting stage and analyzed Cd and Zn concentration as well as Cd and Zn fraction and chemical properties in soils. At 600 m radius of studied area, Cd and Zn were highly accumulated in the surface soils (0 - 20 cm) showed greater than the Korean warning criteria (Cd 1.5, Zn 300 mg $kg^{-1}$) with corresponding values 1.7 and 407 mg $kg^{-1}$, respectively. The leaf part gave higher Cd concentration with the corresponding value of 9.5 mg $kg^{-1}$ as compared to the stem and grains pare (1.6 and 0.18 mg $kg^{-1}$), respectively. Higher Zn concentration was also obtained from the leaf part of the corn plant which gave the value of 1,733 mg $kg^{-1}$. The stem and grain part gave corresponding values of 547 and 61 mg $kg^{-1}$. The order of the mean Cd concentration in fractions is F3 (oxidizable fraction) > F2 (reducible fraction) > F4 (residual fraction) > F1 (exchangeable + acidic fraction). A highly positive correlation is observed between F2 and concentration of Cd and Zn in both plant pare, leaf and grain. Highly positive correlations are shown in the pH exchangeable Ca and Mg, and CEC when correlated with Cd and Zn bound to F4 fractions. To reduce Cd and Zn uptake by corn plant in an arable land heavily contaminated with Cd and Zn as affected by smelting factory, an efficient and effective soil management to increase soil pH and CEC is thus recommended.

충남지역 일부 남자 고등학생들의 스트레스와 구강건강관련 삶의 질과의 관련성 연구 (A Study of the Relation of Stress to Oral Health-Related of Life in Male High School Students of Chungnam)

  • 정유연
    • 치위생과학회지
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    • 제14권2호
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    • pp.158-166
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    • 2014
  • 본 연구는 남자 고등학생들의 스트레스와 구강건강의 중요성 및 주관적 구강건강상태 인식, 칫솔질 횟수에 따른 스트레스와 구강건강관련 삶의 질에 대한 연관성을 파악하여 고등학생들에 대한 실질적인 구강보건교육 필요성을 강조하며 청소년기의 구강위생관리가 올바르게 이루어져 성인 및 노인기까지 구강건강이 유지 증진되어 전반적인 삶의 질이 향상될 수 있는 기초자료를 제공하고자 한다. 2013년 5월부터 7월까지 충남에 위치한 2개 고등학교 1, 2학년을 대상으로 편의표본추출법에 의한 자기기입식으로 설문조사를 실시하였다. PASW Statistics 18.0과 AMOS 5.0 프로그램을 이용하여 다음과 같은 결과를 얻었다. 잠재변수 스트레스가 하위 5가지 영역의 스트레스와 구강건강관련 삶의 질과의 관련성을 분석결과 모두 유의한 것으로(p<0.001)로 나타났으며, 스트레스가 구강건강관련 삶의 질에 주는 영향력은 구강건강의 중요성 인식에 따라 구강건강이 중요하지 않다고 인식할 때보다(-0.38, p<0.001), 중요하다고 인식할 때(-0.32, p<0.001) 구강건강관련 삶의 질이 높은 것으로 나타나 스트레스의 영향이 낮은 것을 알 수 있으며, 주관적 구강건강 인식에서 또한 스스로 구강건강이 좋다고 인식할 때 스트레스의 영향력이-0.14 (p<0.05)로 낮게 나타나 구강건강관련 삶의 질이 높은 것으로 나타났다. 구강건강관리 행태와의 관련성에서는 하루 칫솔질 횟수가 1회로 낮을 때 스트레스가 구강건강의 삶의 질에 주는 영향력이 -0.69 (p<0.001)로 매우 높아 구강건강관련 삶의 질에도 매우 부정적인 영향을 주었다. 이상의 결과를 바탕으로 모델의 적합도 검정결과 GFI, AGFI, CFI, NFI에서 모두 0.9 이상을 보였으며, RMR과 RMSEA 값이 모두 0.1보다 작은 값이 추정되어 양호한 모형이다. 본 연구결과 스트레스와 구강건강관련 삶의 질은 연관성이 있다고 볼 수 있다. 또한 학생들의 구강건강 중요성 인식과 주관적 구강건강 인식도는 구강건강관련 삶의 질과 연관성이 있음을 확인되었고, 구강위생 관리 행태 중 칫솔질 횟수와도 연관성이 나타났다. 그러므로 본인의 구강건강을 스스로 책임져야 할 시기인 고등학생들이 구강건강을 위하여 바람직한 인식과 습관 형성을 위한 실질적이고 체계적인 구강보건교육이 시행되야 할 것이다.

초산부, 경산부 초유 중 PCDDs, PCDFs, dioxin-like PCBs의 축적수준 및 상관성 평가 (Residual Consistency and Interrelationship Estimation of PCDDs, PCDFs, Dioxin-like PCBs in Colostrum of Primipara and Multipara)

  • 위성욱;김기호;조유진;조봉희;박상아;백인천;강성훈;윤조희;민병윤
    • 생명과학회지
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    • 제20권7호
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    • pp.1078-1085
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    • 2010
  • PCDDs, PCDFs, dl-PCBs는 많은 역학 연구에서 독성오염물질이라고 간주되고 있는 생물축적 화학물질이다. 본 연구는 산모 초유 중에 이들 오염물질을 조사 분석하여 산모특성에 따른 축적성 및 상관성을 평가한 것으로, 실험대상 산모는 2007년에 평균연령 31.5세(표준편차=3.6세)의 건강한 초산부와 경산부이다. PCDDs 7개 이성질체, PCDFs 10개 이성질체, non-ortho PCBs 4개와 mono-ortho PCBs 8개 이성질체가 HRGC/HRMS로 분석되었다. 총 WHO-TEQs 평균값은 9.41 pg TEQ/g lipid로 다른 나라 농도에 비하여 낮은 수준이었다. 백분율의 증가와 함께 총 WHO-TEQs의 주요 기여자는 2,3,4,7,8-PeCDF, 1,2,3,7,8-PeCDD 및 3,3‘,4,4’,5-PCB (#126)이며, 총 WHO-TEQs의 60% 이상으로 나타났다. PCDFs 농도와 총 WHO-TEQs는 출산경험에 대해서는 음의 상관관계를 나타내었으며(p<0.05) 산모의 연령은 총 WHO-TEQs에 대해서 양의 상관관계를 나타내었다(p<0.01). 그러나, 임신 전 체질량지수와 어류섭취의 상관관계는 유의성이 없었다. 이들 결과로부터 출산경력과 산모 연령은 모유 내의 PCDD/DFs 및 dl-PCBs의 농도에 영향을 미치는 중요한 인자로 판단된다.