• 한국산학기술학회논문지
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• 제10권12호
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• pp.3963-3970
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• 2009

본 연구에서는 컴퓨터를 이용하여 미술치료에서 윤곽선의 예리성으로 형태를 평가하고 컬러이미지스케일을 통해 색채를 평가하여 '부드러운-딱딱한'의 정도를 정량적으로 평가하는 방법을 제안한다. 회귀모형을 사용하며 종속 변수는 색채 전문가가 그림을 '부드러운-딱딱한'으로 평가한 순위가 된다. 독립변수는 그림의 명도 및 채도의 평균과 표준편차, 그림의 색채 수, 픽셀의 양, 클러스터의 수, 윤곽선의 길이 및 예리성 등을 고려한다. 단계별 회귀분석에 의하여 종속변수를 설명하는 적절한 독립변수들을 선정한다. 평가자 간의 신뢰성을 살피고 평가자 순위와 시스템 순위 간의 순위상관계수를 통해 시스템의 타당성을 입증한다. 객관적이고 정량적 평가를 가능케 함으로써 색채심리 연구, 미술치료뿐만 아니라 패션, 섬유, 인테리어 산업 등에 유용한 정보를 제공한다.

• 재활치료과학
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• 제4권1호
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• pp.53-62
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• 2015

목적 : 본 연구의 목적은 치매노인에게 다감각과 신체활동을 병합한 그룹 활동 프로그램이 이상행동과 보호자 고통정도의 감소에 영향을 주는지 알아보고자 하였다. 연구방법 : 본 연구는 치매전문요양원에 입소하여 생활하는 5명의 중증 이상의 치매노인을 대상으로 4주간 프로그램을 적용하였다. 프로그램 효과를 검증하기 위해 사용한 평가도구는 신경정신행동검사(Neuropsychiatric Inventory)였고, 12가지 이상행동빈도와 이에 따른 요양보호사의 고통정도를 프로그램 전과 후로 나누어 각각 측정하였다. 결과분석은 비모수 통계방법인 윌콕슨 부호 순위 검정(Wilcoxon signed rank test)을 사용하였다. 결과 : 치매노인의 이상행동증상 빈도의 평균이 70점에서 48점으로 감소하였고, 보호자의 고통정도는 평균이 47점에서 29점으로 감소하였다. 결론 : 본 연구의 결과를 통해 요양원 거주인의 다감각과 신체활동을 적용한 그룹 활동 프로그램이 중증 이상의 치매 노인에게 이상행동과 요양보호사 고통정도가 감소하는데 긍정적인 효과가 있음이 증명되었다.

• 가족자원경영과 정책
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• 제3권1호
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• pp.1-15
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• 1999

The purpose of this study is to find out the tendency of the new generation’s consumer roles and green consumption behavior for the environmental conservation. This study is also to reveal some fundamental information for an environmental education program which si able to support the new generation consumers to participate voluntarily in an environmental activity. The 500 subjects of this study were selected from the new generation consumers who wre residing in Seoul, 1998. The 414 data wre finally analyzed by Mean, t-Test, ANOVA, and Multiple Regression Analysis. The major findings were as follows: 1) the purchasing roles of the new generation consumer tended to be higher than the citizen participation’s roles. The variables with the higher score for the new generation’s green consumption behavior were in the rank of the isolation of environmental waste, the purchasing behavior of green product, the recycling environmental resource, and citizen’s participating roles in environmental activity. 2) the new generation’s consumer roles showed a significant differences, according to variables for the environmental value, environmental education, and participation of the environmental and societal activity 3) the green consumption behavior for the new generation consumers showed a significant differences, according to sex, environmental value, participation of the environmental and societal activity. 4) the most influential variables for the green consumption behavior of the new generation consumers were in the rank of consumer roles, educational values, and the participation of the environmental activity. As we see above, the consumer education for the new generations needs to focus on consumer’s roles that let them participate voluntarily in environmental and societal activity, as well as practice positively to use green environmental products whenever they select some items in the markets.

• 대기
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• 제22권4호
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• pp.415-427
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• 2012

$CO_2$ is the most important trace gas related to climate change. Therefore, understanding surface carbon sources and sinks is important when seeking to estimate the impact of $CO_2$ on the environment and climate. CarbonTracker, developed by NOAA, is an inverse modeling system that estimates surface carbon fluxes using an ensemble Kalman filter with atmospheric $CO_2$ measurements as a constraint. In this study, to investigate the capability of CarbonTracker as an analysis tool for estimating surface carbon fluxes in Asia, an experiment with a nesting domain centered in Asia is performed. In general, the results show that setting a nesting domain centered in Asia region enables detailed estimations of surface carbon fluxes in Asia. From a rank histogram, the prior ensemble spread verified at observational sites located in Asia is well represented with a relatively flat rank histogram. The posterior flux in the Eurasian Boreal and Eurasian Temperate regions is well analyzed with proper seasonal cycles and amplitudes. On the other hand, in tropical regions of Asia, the posterior flux does not differ greatly from the prior flux due to fewer $CO_2$ observations. The root mean square error of the model $CO_2$ calculated by the posterior flux is less than the model $CO_2$ calculated by the prior flux, implying that CarbonTracker based on the ensemble Kalman filter works appropriately for the Asia region.

• 대한두경부종양학회지
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• 제37권2호
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• pp.25-31
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• 2021

Background/Objectives: Although thyroid lobectomy recently is considered as sufficient for low-risk papillary thyroid carcinoma (PTC), completion thyroidectomy is required due to the insufficiency of the preoperative evaluation. The aim of this study was to investigate recurrence rate and disease free survival depending on the gross extrathyroidal extension (gETE) or the number of metastatic lymph node identified in patients with PTC. Materials & Methods: We assessed 3373 patients with PTC who underwent lobectomy at Seoul St. Mary's Hospital (Seoul, Korea) between January 2009 and December 2014. Clinicopathological characteristics and long-term surgical outcomes were retrospectively analyzed through complete chart reviews. The mean follow-up duration was 97.1 ± 21.4 months. Results: The rate of recurrence was higher in gETE group (1.8% vs. 6.0%, p=0.004), leading to decreased disease free survival in Kaplan-Meier analysis (log-rank p<0.001). N1 group (n=1389) was analyzed into two groups whether the number of positive nodes is more than 5 or less. For the group of the more metastatic nodes, the recurrence rate higher compared to the other group (3.0% vs. 9.3%, p<0.001). DFS was longer in the group that had lesser metastatic nodes (log-rank p<0.001). However, in terms of N1 group over 1cm (n=492), No statistical difference was observed according to the number of positive lymph nodes (4.5% vs. 9.1%, p=0.092) Conclusion: When it comes to node positive PTC, Despite the number of positive lymph nodes was over 5, follow-up with no further surgery can be an option.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.159-163
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• 2016

Background: Colorectal cancer (CRC) is the third most common cancer in the world, and the fourth in Iran in both genders. The aim of this study was to find predictive factors for CRC survival. Materials and Methods: Medical records of 570 patients referred to the radiotherapy oncology department of Shiraz Namazi hospital from 2005 to 2010 were retrospectively analysed. Data were collected by reviewing medical records, and by telephone interviews with patients. Survival analysis was performed using the Cox's regression model with survival probability estimated with Kaplan-Meier curve. The log-rank test was used to compare survival between strata. Data was analyzed with Stata 12. Results: The five-year survival rate and the mean survival time after cancer diagnosis were 58.5% and $67{\pm}4months$. On multivariate analysis, age of diagnosis, disease stage and primary tumor site, lymphovascular invasion and type of treatment (in colon cancer) were significant factors for survival. Conclusions: Age of diagnosis and type of treatment (adjuvant therapy in patients with colon cancer) were two modifiable factors related to survival of CRC patients. Therefore earlier diagnosis might help increase survival.

• Journal of Forest and Environmental Science
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• 제38권4호
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• pp.290-301
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• 2022

Increasing life expectancy leads to a rise in the prevalence of aging-related mental diseases and a concomitant increase in the financial and societal pressures related to their prevention and management. This issue is attracting increasing attention from researchers. Therefore, this study aimed to determine whether a healing program in a forest environment is effective for improving cognitive function, depression, anxiety, and stress in elderly people. A nonequivalent control group pretest-posttest design was used. The experimental group consisted of 18 males and females aged 60 to 80 years who participated in a forest healing program for seven days, while the comparison group comprised 10 people with similar demographics. For the process of data analysis, this study performed a cross-analysis to determine the homogeneity of the data and carried out the Wilcoxon signed-rank test, a nonparametric statistical test, to verify the significance of each group. Participation in the forest healing program led to a significant improve-ment in cognitive function (p=0.030). The levels of depression decreased, but this result was not statistically significant. The levels of anxiety decreased significantly (p=0.004). The mean cortisol score, a measurement of stress, decreased, but it was not statistically significant. These findings confirmed the effectiveness of this program for improving certain mental conditions of elderly people, and affirmed that the use of long-term forest healing programs can be expected to alleviate national pressures created by aging societies.

• 대한의생명과학회지
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• 제29권4호
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• pp.355-362
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• 2023

This study aimed to determine whether smoking affects the metabolic syndrome and its components through long-term follow-up. Of the 10,030 cohort subjects in the community-based Korean Genome and Epidemiology Study (KoGES) from 2001 to 2018, 2,848 people with metabolic syndrome and 4,854 people with insufficient data for analysis were excluded for this study. The study population comprised 2,328 individuals (1,123 men, 1,205 women) who were eligible for inclusion. The mean age of the participants was 49.2±7.5 years, and 21.9% were current smoker. In log rank test, current smoker had a significantly higher cumulative incidence of metabolic syndrome compared with non smoker (P<0.001). In the Cox proportional hazards model adjusted for key variables, metabolic syndrome (hazard ratio [HR] 1.57, P<0.001), high fasting glucose (HR 1.40, P<0.01), hypertriglyceridemia (HR 1.60, P<0.001), low HDL-cholesterol (HR, 1.30, P<0.01), and abdominal obesity (HR 1.32, P<0.01) in current smoker compared with non smoker were statistically significant, respectively, but not hypertension (HR 1.00, P>0.05). After adjustment for confounders, the time (P-time<0.001) and group (P-group<0.001) effects on metabolic syndrome score change were statistically significant. Furthermore, the interaction analysis of time and smoking group on the change in metabolic syndrome score was statistically significant (P-interaction<0.001). In long-term follow-up, smoking worsens metabolic syndrome.

• Korean Journal of Radiology
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• 제21권6호
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• pp.707-716
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• 2020

Objective: To evaluate pharmacokinetic variables from contrast-enhancing lesions (CELs) and non-enhancing T2 high signal intensity lesions (NE-T2HSILs) on dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging for predicting progression-free survival (PFS) in glioblastoma (GBM) patients. Materials and Methods: Sixty-four GBM patients who had undergone preoperative DCE MR imaging and received standard treatment were retrospectively included. We analyzed the pharmacokinetic variables of the volume transfer constant (Ktrans) and volume fraction of extravascular extracellular space within the CEL and NE-T2HSIL of the entire tumor. Univariate and multivariate Cox regression analyses were performed using preoperative clinical characteristics, pharmacokinetic variables of DCE MR imaging, and postoperative molecular biomarkers to predict PFS. Results: The increased mean Ktrans of the CEL, increased 95th percentile Ktrans of the CELs, and absence of methylated O⁶-methylguanine-DNA methyltransferase promoter were relevant adverse variables for PFS in the univariate analysis (p = 0.041, p = 0.032, and p = 0.083, respectively). The Kaplan-Meier survival curves demonstrated that PFS was significantly shorter in patients with a mean Ktrans of the CEL > 0.068 and 95th percentile Ktrans of the CEL > 0.223 (log-rank p = 0.038 and p = 0.041, respectively). However, only mean Ktrans of the CEL was significantly associated with PFS (p = 0.024; hazard ratio, 553.08; 95% confidence interval, 2.27-134756.74) in the multivariate Cox proportional hazard analysis. None of the pharmacokinetic variables from NE-T2HSILs were significantly related to PFS. Conclusion: Among the pharmacokinetic variables extracted from CELs and NE-T2HSILs on preoperative DCE MR imaging, the mean Ktrans of CELs exhibits potential as a useful imaging predictor of PFS in GBM patients.

• Archives of Plastic Surgery
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• 제48권4호
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• pp.457-461
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• 2021

Background Pedicled perforator flaps can present postoperative complications similar to those encountered in free flap surgery. Beyond a clinical evaluation, there is still no reliable technical aid for the early prediction of vascular issues. The aim of this study was to assess the support of near-infrared spectroscopy technology as an intraoperative tool to anticipate postsurgical flap ischemia. Methods We prospectively enrolled 13 consecutive patients who were referred to our hospital from March 2017 to July 2018 and required a reconstructive procedure with a pedicled fasciocutaneous perforator flap. We measured flap peripheral capillary oxygen saturation (SpO₂) in each patient with a Somanetics INVOS 5100C Cerebral/Somatic Oximeter (Medtronic), both before and after transposition. Patient demographics, operative data, and complications were then recorded during the following 6 months. We analyzed the data using the Wilcoxon signed-rank test and linear regression. Results The mean flap SpO₂ before and after transposition was 92%±3% and 78%±19%, respectively. The mean change in SpO₂ was 14%±17%, with a range of 0% to 55%. The change in saturation and mean saturation ratio were significantly different between patients with and without postoperative flap necrosis. Conclusions An immediate quantitative analysis of flap peripheral capillary SpO₂ after transposition has never before been described. In our experience, an intraoperative drop in SpO₂ equal to or greater than 15%-20% predicted vascular complications in pedicled perforator flaps. Conversely, flap size and rotation angle were not correlated with the risk of flap necrosis.