• Title/Summary/Keyword: Maxwell

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The Presence of Neural Stem Cells and Changes in Stem Cell-Like Activity With Age in Mouse Spiral Ganglion Cells In Vivo and In Vitro

  • Moon, Byoung-San;Ammothumkandy, Aswathy;Zhang, Naibo;Peng, Lei;Ibrayeva, Albina;Bay, Maxwell;Pratap, Athira;Park, Hong Ju;Bonaguidi, Michael Anthony;Lu, Wange
    • Clinical and Experimental Otorhinolaryngology
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    • v.11 no.4
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    • pp.224-232
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    • 2018
  • Objectives. Spiral ganglion neurons (SGNs) include potential endogenous progenitor populations for the regeneration of the peripheral auditory system. However, whether these populations are present in adult mice is largely unknown. We examined the presence and characteristics of SGN-neural stem cells (NSCs) in mice as a function of age. Methods. The expression of Nestin and Ki67 was examined in sequentially dissected cochlear modiolar tissues from mice of different ages (from postnatal day to 24 weeks) and the sphere-forming populations from the SGNs were isolated and differentiated into different cell types. Results. There were significant decreases in Nestin and Ki67 double-positive mitotic progenitor cells in vivo with increasing mouse age. The SGNs formed spheres exhibiting self-renewing activity and multipotent capacity, which were seen in NSCs and were capable of differentiating into neuron and glial cell types. The SGN spheres derived from mice at an early age (postnatal day or 2 weeks) contained more mitotic stem cells than those from mice at a late age. Conclusion. Our findings showed the presence of self-renewing and proliferative subtypes of SGN-NSCs which might serve as a promising source for the regeneration of auditory neurons even in adult mice.

Isogeometric Analysis of Electrostatic Adhesive Forces in Two-Dimensional Curved Electrodes (2차원 곡면형 전극에서 정전기 흡착력의 아이소-지오메트릭 해석)

  • Oh, Myung-Hoon;Kim, Jae-Hyun;Kim, Hyun-Seok;Cho, Seonho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.34 no.4
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    • pp.199-204
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    • 2021
  • In this study, an isogoemetric analysis (IGA) method that uses NURBS (Non-Uniform Rational B-Spline) basis functions in computer-aided design (CAD) systems is employed to account for the geometric exactness of curved electrodes constituting an electro-adhesive pad in electrostatic problems. The IGA is advantageous for obtaining precise normal vectors when computing the electro-adhesive forces on curved surfaces. By performing parametric studies using numerical examples, we demonstrate the superior performance of the curved electrodes, which is attributed to the increase in the normal component of the electro-adhesive forces. In addition, concave curved electrodes exhibit better performance than their convex counterparts.

Dynamic response of FG porous nanobeams subjected thermal and magnetic fields under moving load

  • Esen, Ismail;Alazwari, Mashhour A.;Eltaher, Mohamed A;Abdelrahman, Alaa A.
    • Steel and Composite Structures
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    • v.42 no.6
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    • pp.805-826
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    • 2022
  • The free and live load-forced vibration behaviour of porous functionally graded (PFG) higher order nanobeams in the thermal and magnetic fields is investigated comprehensively through this work in the framework of nonlocal strain gradient theory (NLSGT). The porosity effects on the dynamic behaviour of FG nanobeams is investigated using four different porosity distribution models. These models are exploited; uniform, symmetrical, condensed upward, and condensed downward distributions. The material characteristics gradation in the thickness direction is estimated using the power-law. The magnetic field effect is incorporated using Maxwell's equations. The third order shear deformation beam theory is adopted to incorporate the shear deformation effect. The Hamilton principle is adopted to derive the coupled thermomagnetic dynamic equations of motion of the whole system and the associated boundary conditions. Navier method is used to derive the analytical solution of the governing equations. The developed methodology is verified and compared with the available results in the literature and good agreement is observed. Parametric studies are conducted to show effects of porosity parameter; porosity distribution, temperature rise, magnetic field intensity, material gradation index, non-classical parameters, and the applied moving load velocity on the vibration behavior of nanobeams. It has been showed that all the analyzed conditions have significant effects on the dynamic behavior of the nanobeams. Additionally, it has been observed that the negative effects of moving load, porosity and thermal load on the nanobeam dynamics can be reduced by the effect of the force induced from the directed magnetic field or can be kept within certain desired design limits by controlling the intensity of the magnetic field.

A machine learning-based model for the estimation of the critical thermo-electrical responses of the sandwich structure with magneto-electro-elastic face sheet

  • Zhou, Xiao;Wang, Pinyi;Al-Dhaifallah, Mujahed;Rawa, Muhyaddin;Khadimallah, Mohamed Amine
    • Advances in nano research
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    • v.12 no.1
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    • pp.81-99
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    • 2022
  • The aim of current work is to evaluate thermo-electrical characteristics of graphene nanoplatelets Reinforced Composite (GNPRC) coupled with magneto-electro-elastic (MEE) face sheet. In this regard, a cylindrical smart nanocomposite made of GNPRC with an external MEE layer is considered. The bonding between the layers are assumed to be perfect. Because of the layer nature of the structure, the material characteristics of the whole structure is regarded as graded. Both mechanical and thermal boundary conditions are applied to this structure. The main objective of this work is to determine critical temperature and critical voltage as a function of thermal condition, support type, GNP weight fraction, and MEE thickness. The governing equation of the multilayer nanocomposites cylindrical shell is derived. The generalized differential quadrature method (GDQM) is employed to numerically solve the differential equations. This method is integrated with Deep Learning Network (DNN) with ADADELTA optimizer to determine the critical conditions of the current sandwich structure. This the first time that effects of several conditions including surrounding temperature, MEE layer thickness, and pattern of the layers of the GNPRC is investigated on two main parameters critical temperature and critical voltage of the nanostructure. Furthermore, Maxwell equation is derived for modeling of the MEE. The outcome reveals that MEE layer, temperature change, GNP weight function, and GNP distribution patterns GNP weight function have significant influence on the critical temperature and voltage of cylindrical shell made from GNP nanocomposites core with MEE face sheet on outer of the shell.

Stability analysis of integrated SWCNT reposed on Kerr medium under longitudinal magnetic field effect Via an NL-FSDT

  • Belkacem Selmoune;Abdelwahed Semmah;Mohammed L. Bouchareb;Fouad Bourada;Abdelouahed Tounsi;Mohammed A. Al-Osta
    • Advances in materials Research
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    • v.12 no.3
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    • pp.243-261
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    • 2023
  • This study aims to analyze the mechanical buckling behavior of a single-walled carbon nanotube (SWCNT) integrated with a one-parameter elastic medium and modeled as a Kerr-type foundation under a longitudinal magnetic field. The structure is considered homogeneous and therefore modeled utilizing the nonlocal first shear deformation theory (NL-FSDT). This model targets thin and thick structures and considers the effect of the transverse shear deformation and small-scale effect. The Kerr model describes the elastic matrix, which takes into account the transverse shear strain and normal pressure. Using the nonlocal elastic theory and taking into account the Lorentz magnetic force acquired from Maxwell relations, the stability equation for buckling analysis of a simply supported SWCNT under a longitudinal magnetic field is obtained. Moreover, the mechanical buckling load behavior with respect to the impacts of the magnetic field and the elastic medium parameters considering the nonlocal parameter, the rotary inertia, and transverse shear deformation was examined and discussed. This study showed useful results that can be used for the design of nano-transistors that use the buckling properties of single-wall carbon nanotubes(CNTs) due to the creation of the magnetic field effect.

South-South Collaborations: A Policy Recommendation Model for Sustainable Win-Win Infrastructure Partnerships Based on Sino - Ghana and Nigeria Case.

  • Eshun, Bridget Tawiah Badu;Chan, Albert P.C.;Oteng, Daniel;Antwi-Afari, Maxwell Fordjour
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.33-41
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    • 2022
  • Infrastructure procurement has been a major engagement route between China and Africa. This contributes immensely to the gradual infrastructure development seen on the continent. However, maturing discourse purports that these infrastructure collaborations lack intentionality in the continuous development of strategic guidelines and policies for effective implementation despite their uniqueness and criticality. This study proposes that an efficient approach to policy recommendations is through the political and economic analysis (PEA) of these partnerships using public-private partnership (PPP) optics. Unquestionably, these partnerships are representative of the concept of diplomatic transnational public-private partnership (DT-PPP) where infrastructure is procured through the collaboration of public (African governments) and private sector (Chinese state-owned corporations) who provide the managerial, financial, and technical resources for the project implementation. Given the quest for sustainable win-win, this study identifies strategies towards the realization of win-win in the implementation (i.e enablers of win-win) such that fairness and co-benefit, as well as interests, will be achieved. Thus, based on the PEA framework, case scenarios from Ghana and Nigeria using expert interviews identify the criticalities and best practices for the realization of these enablers at the development phase. Findings indicate more effort is required of the public sector (African host countries) in terms of people, structure/institutions, and the implementation processes. Recommendations include improvement of environmental management structures, contract administration procedures, external stakeholders/local community engagement mechanisms, knowledge and technology transfer procedures, and sector-based project operation and maintenance culture and systems. Additionally, actors must have emotional intelligence, good problem-solving abilities, and overall ensure cordial relationships for continued bilateral cooperation.

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Dynamic analysis of sandwich plate with viscoelastic core based on an improved method for identification of material parameters in GHM viscoelastic model

  • Mojtaba Safari;Hasan Biglari;Mohsen Motezaker
    • Steel and Composite Structures
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    • v.47 no.6
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    • pp.743-757
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    • 2023
  • In this paper, the dynamic response of a simply-supported composite sandwich plate with a viscoelastic core based on the Golla-Hughes-McTavish (GHM) viscoelastic model is investigated analytically. The formulation is developed using the three-layered sandwich panel theory. Hamilton's principle has been employed to derive the equations of motion. Since classical models, like kelvin-voigt and Maxwell models, cannot express a comprehensive description of the dynamic behavior of viscoelastic material, the GHM method is used to model the viscoelastic core of the plate in this research. The main advantage of the GHM model in comparison with classical models is the consideration of the frequency-dependent characteristic of viscoelastic material. Identification of the material parameters of GHM mini-oscillator terms is an essential procedure in applying the GHM model. In this study, the focus of viscoelastic modeling is on the development of GHM parameters identification. For this purpose, a new method is proposed to find these constants which express frequency-dependent behavior characterization of viscoelastic material. Natural frequencies and loss factors of the sandwich panel based on ESL and three-layered theories in different geometrics are described at 30℃ and 90℃; also, the comparisons show that obtained natural frequencies are grossly overestimated by ESL theory. The argumentations of differences in natural frequencies are also illustrated in detail. The obtained results show that the GHM model presents a more accurate description of the plate's dynamic response by considering the frequency dependency behavior of the viscoelastic core.

A Study on the Transport of Microplastics Contained in the Wastewater of the King Sejong Station according to the Wave Effect (파랑 효과에 따른 세종과학기지 방류수에 포함된 미세플라스틱 이송에 관한 연구)

  • Kim, Bo-Kyung;Hwang, Jin Hwan
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.245-245
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    • 2021
  • 해양으로 유출된 5 mm 이하의 크기로 분해된 미세플라스틱이 해양 환경 오염의 주요 원인으로 자리잡았다. 최근에는 청정해역으로 알려진 남극해에서도 발견되고 있어 남극해에 잔류하는 미세플라스틱 오염 수준을 이해하기 위해 노력하고 있다. 하지만, 파랑의 효과를 고려한 남극해의 해수 순환 구조와 미세플라스틱의 고유 특성을 반영한 미세플라스틱의 거동 및 공간적 분포에 대한 복합적 이해는 상대적으로 부족하다. 남극해에서 발견된 미세플라스틱은 과학기지들의 방류수나, 조사선 등과 같은 인위적인 활동으로 인해 집적될 수 있으며, 특히 영구적으로 거주하는 과학기지에서 흘려보내는 방류수에 포함된 미세플라스틱은 과학기지 주변 해수 오염에 직접적인 영향을 줄 것으로 예상된다. 따라서, 본 연구에서는 파랑 효과에 따른 남극 킹조지 섬(King George Island)에 위치한 세종과학기지의 방류수에 포함된 미세플라스틱의 이송에 대해 모의하였다. 세종과학기지가 위치한 킹조지 섬과 넬슨 섬(Nelson Island) 사이의 멕스웰 만(Maxwell Bay)의 해수 흐름을 재현하기 위하여 해수 유동 모델(Delft3D-FLOW)이 사용되었다. 또한, 해수 유동 모델에 파랑 모델(Delft3D-WAVE)을 결합하여 파랑의 효과가 미세플라스틱의 이송에 미치는 영향을 확인하였다. 세종과학기지의 방류수가 흘러나가는 마리안 소만(Marian Cove)의 유속장을 바탕으로 이송, 확산, 입자의 침강 속도를 고려하여서, 세종과학기지에서 밀물 시 방출한 입자를 라그랑지안 입자 추적(Lagrangian Particle Tracking) 방법을 이용해 추적하였다. 해수의 밀도보다 가벼운 플라스틱의 경우 해수 표층의 흐름을 따라 소만 내부로 이송되어 해안선에 도달하고, 해수의 밀도보다 무거운 플라스틱의 경우 소만 내부로 이송되나 입자의 침강 속도로 인해 방출 위치 근처에서 집적된다. 파랑의 효과를 고려하게 되면, 고려하기 전보다 두 종류의 미세플라스틱 모두 소만 내부로 더 멀리 이송되는데, 이는 파랑으로 인한 힘(wave-induced force)이 해수 유동 모델의 운동방정식에 추가되며 파랑 에너지 분산으로 인해 해수 흐름에 변화를 준 것으로 보인다.

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How do dense cores embedded in a pc scale filamentary clouds form, by gas flow motions along filamentary clouds and/or contracting motions by themselves?

  • Kim, Shinyoung;Lee, Chang Won;Myers, Philip C.;Caselli, Paola;Kim, Mi-Ryang
    • The Bulletin of The Korean Astronomical Society
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    • v.45 no.1
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    • pp.41.2-42
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    • 2020
  • Understanding how the filamentary structure plays a role in the formation of the prestellar cores and stars is a key issue to challenge. We have observed two prestellar cores in surrounding filamentary environments in 13CO, C180 (3-2) and HCO+ (4-3) molecular lines with the Heterodyne Array Receiver Program (HARP) of the James Clerk Maxwell Telescope (JCMT), in order to search for the evidence related to the possible flow motions along the filament and/or the radial accretion (or infalling motions) of gas material toward the dense cores from their surrounding filamentary cloud. In L1544, the velocity gradient of 1.6 km s-1 pc-1 toward the core was measured in a small branch of filament lying on a radial direction of main filament while no velocity gradient along the main axis of filament in both 13CO and C18O lines. In L694-2, we found the velocity gradient of 0.6 km s-1 pc-1 along the filament in only 13CO lines. The projected accretion rate of ~6 M◉ Myr-1 was estimated in both cases. The infall (or radially contracting) velocity of gas material was measured ~0.16 km s-1 in both 13CO and HCO+ lines and in both L1544 and L694-2, which leads to estimate a mass infall rate of ~20 M◉ Myr-1. Our analysis suggests that our targets are at a stage where the gravitational contraction dominates the mass accretion through the surrounding filamentary cloud. This is consistent with the fact that our targets are highly evolved prestellar cores on a verge of star formation. More detailed results will be presented at the meeting.

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Baseflow separation methods based on a single digital filter parameter: sensitivity analysis and applicability review (단일 디지털 필터 매개변수 기반의 기저유출 분리 기법: 민감도 분석 및 적용성 검토)

  • Jin, Youngkyu;Kang, Taeuk;Lee, Namjoo;Lee, Sangho
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.435-435
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    • 2022
  • 디지털 필터 기반의 기저유출 분리 기법은 하천유량으로부터 기저유량을 분리하는 기법으로서 적절한 분석을 위해서는 필터 매개변수에 대한 추정이 요구된다. 이 연구에서는 비교적 간단한 방법으로 기저유출을 분리할 수 있는 단일 매개변수를 가진 디지털 필터 기반의 기저유출 분리 기법에 대하여 민감도 분석을 수행하였으며, 민감도 분석 결과를 바탕으로 적정 매개변수 범위를 결정하였다. 적용된 디지털 필터 기반의 기저유출 분리 기법은 Lyne-Hollick(LH), Chapman, Chapman-Maxwell(CM), EWMA 기법이다. 분석 대상 지점은 낙동강 지류 하천 중 8년이상 연속된 유량측정 기록이 존재하는 25개 수위관측소이다. 민감도 분석을 위한 기저유출 분리 기법별 매개변수 범위는 과거 연구 사례에 근거하여 LH, Chapman, CM 기법의 경우 0.9 ~ 0.99, EWMA 기법은 0.003 ~ 0.015로 선정하였다. 기저유출 분리 기법별 민감도 분석 결과, EWMA 기법이 매개변수 변화에 따른 기저유출 지표의 변화가 가장 적은 것으로 분석되었으며, LH 기법이 민감도가 가장 큰 것으로 분석되었다. 또한, LH 기법과 EWMA 기법은 수위관측소에 따라 산정된 기저유출 지수가 큰 차이를 보였으며, 이는 각 수위관측소의 유황곡선에서 10%와 90%에 해당하는 유량의 무차원 변동량에 기인한 것으로 분석되었다. 각 기저유출 분리 기법별 적용성 검토 결과, Chapman과 CM 기법은 기저유출만 존재하는 비 강우 기간에서 기저유출을 분리하는 오류가 확인됨에 따라, 비교적 유량 변동이 큰 우리나라의 유출 특성상 Chapman과 CM 기법의 적용은 부적절한 것으로 판단된다. LH 기법과 EWMA 기법은 홍수 수문곡선 상승부에 대한 기저유출의 비율, 비 강우 기간에 대한 기저유출 분리 오류 등을 검토하여, EWMA 기법은 0.012 ~ 0.015, LH 기법은 0.950 ~ 0.975로 선정하였다.

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