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Design of Gastrointestinal Diagnosis System based on Ultrasonic Response Characteristics (초음파 응답특성 분석에 의한 위장 경화 진단시스템의 설계)

  • Lim, Do-Hyung;Kim, Eun-Geun;Lee, Gyoun-Jung;Park, Won-Pil;Kim, Han-Sung;Shin, Tae-Min;Choi, Seo-Hyung;Lee, Yong-Heum
    • Journal of Biomedical Engineering Research
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    • v.28 no.2
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    • pp.250-257
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    • 2007
  • Functional gastrointestinal disorders affect millions of people of all age regardless of race and sex. There are, however, rare diagnostic methods for the functional gastrointestinal disorders because functional disorders show no evidence of organic and physical causes. Our research group identified recently that the gastrointestinal tract well in the patients with the functional gastrointestinal disorders becomes more rigid than healthy people when palpating the abdominal regions overlaying the gastrointestinal tract. The aim is, therefore, to develop a diagnostic method for the functional gastrointestinal disorders based on quantitative measurement of the rigidity of the gastrointestinal tract well using ultrasound technique. For this purpose, a preliminary ultrasound diagnostic system was developed and verified through phantom tests. The system consisted of transmitter, ultrasonic transducer, receiver, TGC, and CPLD, and verified via a phantom test. For the phantom test, ten soft-tissue specimens were harvested from porcine. Five of them were then treated chemically to mimic a rigid condition of gastrointestinal tract well, which was induced by functional gastrointestinal disorders. Additionally, the specimens were tested mechanically to identify if the mimic was reasonable. The customized ultrasound system was finally verified through application to human subjects with/without functional gastrointestinal disorders(Normal and Patient Groups). It was identified from the mechanical test that the chemically treated specimens were more rigid than normalspecimen. This finding was favorably compared with the result obtained from the phantom test. The phantom test also showed that ultrasound system well described the specimen geometric characteristics and detected an alteration in the specimens. The maximum amplitude of the ultrasonic reflective signal in the rigid specimens $(0.2{\pm}0.1Vp-p)$ at the interface between the fat and muscle layers was explicitly higher than that in the normal specimens $(0.1{\pm}0.0Vp-p)$ (p<0.05). Clinical tests using our customized ultrasound system for human subject showed that the maximum amplitudes of the ultrasonic reflective signals nea. to the gastrointestinal tract well for the patient group$(2.6{\pm}0.3Vp-p)$ were generally higher than those in normal group$(0.1{\pm}0.2Vp-p)$ (p<0.05). These results suggest that newly designed diagnostic system based on ultrasound technique may diagnose enough the functional gastrointestinal disorders.

Compensation of Error in Noninvasive Blood Pressure Measurement System Using Optical Sensor (광학 센서를 이용한 비관혈적 혈압 측정의 오차 보정)

  • Ko, J.I.;Jeong, I.C.;Lee, D.H.;Park, S.W.;Hwang, S.O.;Park, S.M.;Kim, G.Y.;Joo, H.S.;Yoon, H.R.
    • Journal of Biomedical Engineering Research
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    • v.28 no.2
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    • pp.178-186
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    • 2007
  • This study is attempted to correct an error of electronic blood pressure meter with an optical sensor. In general, for a hospitalized patient, ECG, blood pressure, oxygen saturation, and respiration are basically measured to monitor the patient's condition. Opening of a blood vessel after it is occluded by pressurizing the cuff influences the blood flow of peripheral blood vessels as well as oscillation changes in the cuff. Blood vessels are occluded and peripheral blood flow disappears at cuff pressure above the examinee's blood pressure, while blood vessels are opened and peripheral blood flow appears again at cuff pressure under the examinee's blood pressure. Then Disappear-Appear Point Length(DAPL) of peripheral blood flow can be judged with the signal of peripheral blood flow, thus is available as a factor of error correction for electronic blood pressure meter. Also, systolic or diastolic blood pressure can be corrected with Appear-Point-Pressure(APP) of cuff pressure at a point where blood flow occurs and Appear-Maximum Pressure(AMP) of cuff pressure at the maximum amplitude point of peripheral blood flow after peripheral blood flow appears again. For verification, 27 examinees were selected, and their blood value was obtained through experimental procedure of 4 stages including induction of blood pressure change. The examinees were divided into two groups of experimental group and control group, regression analysis was conducted for experimental group, and correction of a blood pressure error was verified with optical signal by applying the regression equation calculated in experimental group to control group. As an experimental result, mean of the whole measurement errors was 5mmHg or more, which did not meet the standard fur blood pressure meter. As a result of correcting blood pressure measurements with data of DAPL, APP, and AMP as drawn out of PPG signal, systolic blood pressure, mean blood pressure, and diastolic blood pressure were $-0.6{\pm}4.4mmHg,\;-1.0{\pm}3.9mmHg$ and $-1.3{\pm}5.4mmHg$, respectively, indicating that mean of the whole measurement errors was greatly improved, and standard deviation was decreased.

Development of the Line Scan Diffusion Weighted Imaging at Low Tesla Magnetic Resonance Imaging System (저자장 자기공명영상시스템에서 선주사확산강조영상기법 개발)

  • Hong, Cheol-Pyo;Lee, Dong-Hoon;Lee, Do-Wan;Lee, Man-Woo;Paek, Mun-Young;Han, Bong-Soo
    • Journal of the Korean Society of Radiology
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    • v.2 no.2
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    • pp.31-38
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    • 2008
  • Line scan diffusion weighted imaging (LSDI) pulse sequence for 0.32 T magnetic resonance imaging (MRI) system was developed. In the LSDI pulse sequence, the imaging volume is formed by the intersection of the two perpendicular planes selected by the two slice-selective $\pi$/2-pulse and $\pi$-pulse and two diffusion sensitizing gradients placed on the both side of the refocusing $\pi$-pulse and the standard frequency encoding readout was followed. Since the maximum gradient amplitude for the MR system was 15 mT/m the maximum b value was $301.50s/mm^2$. Using the developed LSDI pulse sequence, the diffusion weighted images for the aqueous NaCl solution phantom and triacylglycerol solution phantom calculated from the line scan diffusion weighted images gives the same results within the standard error range (mean diffusivities = $963.90{\pm}79.83({\times}10^{-6}mm^2/s)$ at 0.32 T, $956.77{\pm}4.12({\times}10^{-6}mm^2/s)$ at 1.5 T) and the LSDI images were insensitive to the magnetic susceptibility difference and chemical shift.

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Tide and Tidal Currents Around the Archipelago on the Southwestern Waters of the South Sea, Korea (한국 남서해 다도해역의 조석·조류 특성)

  • Choo, Hyo-Sang;Kim, Dong-Sun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.19 no.6
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    • pp.582-596
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    • 2013
  • In order to estimate the tide and flow properties around the archipelago, around Dolsan, Choyak, Geogeom and Jindo which located in the southwestern waters of the south sea of Korea, tidal currents, residual flows and tidal energy dissipation were investigated by using 2-dimensional numerical model. The maximum speeds of tidal currents are small around Dolsando(31.92 cm/s) and large around Jindo(87.55 cm/s). The residual flow is fastest around Choyakdo where many channels and islands as compared with other study areas. The area around Jindo has the highest currents speed, but shows the flat movements. The margins between the maximum and the minimum dispersion rates of tidal energy in the areas are estimated and designate the order of values around Dolsando($392.6{\times}10^7$ erg/s), Geogeumdo($125.7{\times}10^7$ erg/s) and Jindo($23.1{\times}10^7$ erg/s) sequently. These circumstances are same as in the amplitude of M2 constituent. This means that rapid depth changes and narrow channels play an important role in tide and tidal currents energy in archipelago.

Performance Evaluation of DSE-MMA Blind Equalization Algorithm in QAM System (QAM 시스템에서 DSE-MMA 블라인드 등화 알고리즘의 성능 평가)

  • Kang, Dae-Soo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.13 no.6
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    • pp.115-121
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    • 2013
  • This paper related with the DSE-MMA (Dithered Sign-Error MMA) that is the simplification of computational arithmetic number in blind equalization algorithm in order to compensates the intersymbol interference which occurs the passing the nonlinear communication channel in the presence of the band limit and phase distortion. The SE-MMA algorithm has a merit of H/W implementation for the possible to reduction of computational arithmetic number using the 1 bit quantizer in stead of multiplication in the updating the equalizer tap weight. But it degradates the overall blind equalization algorithm performance by the information loss at the quantization process compare to the MMA. The DSE-MMA which implements the dithered signed-error concepts by using the dither signal before qualtization are added to MMA, then the improved SNR performance which represents the roburstness of equalization algorithm are obtained. It has a concurrently compensation capability of the amplitude and phase distortion due to intersymbol interference like as the SE-MMA and MMA algorithm. The paper uses the equalizer output signal, residual isi, MD, MSE learning curve and SER curve for the performance index of blind equalization algorithm, and the computer simulation were performed in order to compare the SE-MMA and DSE-MMA applying the same performance index. As a result of simulation, the DSE-MMA can improving the roburstness and the value of every performance index after steady state than the SE-MMA, and confirmed that the DSE-MMA has slow convergence speed which meaning the reaching the seady state from initial state of adaptive equalization filter.

Flow Visualization of Acoustic Streaming Induced by Ultrasonic Vibration Using Particle Imaging Velocimetry (PIV를 이용한 초음파 진동에 의해 유도된 음향유동의 가시화)

  • 노병국;권기정;이장연;이동렬
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.14 no.6
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    • pp.528-535
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    • 2004
  • Ultrasonic Vibrator is designed to achieve the maximum vibration amplitude at 30 kHz by in-cluding a horn (diameter, 40 mm), mechanical vibration amplifier at the top of the ultrasonic vibrator in the system and making the complete system resonate. In addition, it is experimentally visualized by particle imaging velocimetry (PIV) that the acoustic streaming velocity in the gap is at maximum when the gap between the ultrasonic vibrator and stationary plate agrees with the multiples of half-wavelength of the ultrasonic wave. This fact results from the resonance of the sound wave and the theoretical analysis of that is also accomplished and verified by experiment. It is observed that the magnitude of the acoustic streaming dependent upon the gap between the ultrasonic vibrator and stationary plate possibly changes due to the measurement of the average velocity fields of the acoustic streaming induced by the ultrasonic vibration at resonance and non-resonance. There exists extremely small average velocity at non-resonant gaps while the relatively large average velocity exists at resonant gaps compared with non-resonant gaps. It also reveals that there should be larger axial turbulent intensity at the hub region of the vibrator and at the edge of it in the resonant gap where the air streaming velocity is maximized and the flow phenomena is conspicuous than that at the other region. Because the variation of the acoustic streaming velocity at resonant gap is more distinctive than that at non-resonant gap, shear stress increases more in the resonant gap and is also maximized at the center region of the vibrator except the local position of center (r〓0). At the non-resonant gap there should be low values of vorticity distribution, but in contrast to the non-resonant gap, high and negative values of it exist at the center region of the vibrator with respect to the radial direction and in the vicinity of the middle region with respect to the axial direction. Acoustic streaming is noise-free due to the ultrasonic vibration and maintenance-free because of the absence of moving parts. Moreover, the proposed method by acoustic streaming can be utilized to the nano and micro-electro mechanical systems as a driving mechanism in addition to the augmentation of the streaming velocity.

Endogenous Rhythms of $CO_2$ Assimilation, Stomatal Conductance and Soluble Carbohydrate Concentration during Grain Filling in Rice (벼 등숙기간중 $CO_2$ 동화율, 기공전도도 및 수용성 탄수화물 농도의 내생 리듬)

  • 현동윤
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.5
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    • pp.556-561
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    • 1995
  • Persisent circadian rhythms in carbon assimilation, stomatal conductance and soluble carbohydrate concentration were investigated during grain filling period in rice plant transferred from a natural photoperiod to constant conditions. A weak rhythm in photosynthesis, measured as carbon assimilation, and stomatal opening, as conductance to water vapor, with a period of approximately 24-hours, occurred under constant condition. Carbon assimilation and stomatal conductance reached maximum values near noon and minimum values near midnight during the early stage (until 72-hour) after transferring to constant condition, and then the amplitude and phase were changed slowly, the rhythms with little damping, reaching maximum values near midnight and minimum values near noon during 96~120-hours after transferring. However, photosynthesis in plants grown for 14days after anthesis under constant moderate light(day and night) did not oscillated in constant condition unlike plants grown under a cycle of light and darkness. These phenomenon was observed in soluble carbohydrate concentration in flag leaves as well. Evidences from several approaches indicate that endogenous rhythms of $CO_2$ assimilation, stomatal conductance and soluble carbohydrate concentration are closely couped with each other and particularly important to plants, which depend on the natural day-night cycle as a external signal.

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Clinical Observation on Voice Disorder (음성장애에 대한 임상적고찰)

  • 이종원
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1979.05a
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    • pp.7.2-8
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    • 1979
  • The tests related to air usage are valuable for evaluating phonatory function of clinical cases having glottic incompetence. Measurement of mean air flow rate, maximum phonation time and phonation quotient are important test for voice disorder. Stroboscopy is very useful for clinical evaluation of abnormality in the mode of vocal cord vibration. Author obtained following clinical result from 56 cases of laryngeal disorders in Kurume medical school in Japan. 1) Unilateral laryngeal lesions, are 35 cases (62.5%) and bilateral laryngeal lesions are 21 cases (37.5%). 2) Sex ratio is 39 cases (69.8%) of male and 17 cases (30.2%) of female. 3) In maximum phonation time below 10 seconds are 26 cases (46.4%) and above 10 seconds are 30 cases (53.6%). 4) In phonation quotient below 300 ml/sec are 33cases (58.9%). and above 300ml/sec are 23 cases (41.0%). 5) In mean air flow rate below 300ml/sec are 37 cases (66.1%) and above 300ml/sec are 19 cases (33.9%). 6) Symmetry of vibratory movement of the vocal cord, regularity of vibration, amplitude of vibration, wave on the mucosa and glottic closures are observed by stroboscopic examination. 7) Postoperative voice test and stroboscopic examination revealed good result in compare pre-operation with post-operation.

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The Behavior of Dry Sand under Dynamic Loading -A Study on the Vertical Vibration (건조사질토의 동적거동 -수직진동에 의한 연구)

  • Kim, Su-Il;Jeong, Sang-Seom;An, Yeong-Hun
    • Geotechnical Engineering
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    • v.11 no.4
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    • pp.37-48
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    • 1995
  • The dynamic behavior of dry sand under different vibration conditions is studied through laboratory experiments. Sinusoidal and random vibration experiments of sand are carried out in vertical direction under various surcharge loads. Five different sand samples are selected for the azperiment. They are composed of four different -size samples of particles and one sample which is simulated the field condition. In case of sinusoidal vibration, the change in relative density is measured with acceleration levels. To produce an acceleration, the vibration amplitude is maintained within the range of 0.4mm~0.6mm and the vibration frequency is changed within the range of 3Hz~40Hz. In case of random vibration, the combined sinusoidal acceleration is produced by a random vibration generator and the change in relative density is measured by an accelerometer. Based on the experimental results, it is found that the sandy soil is compacted to 94%~99% of relative density by vertical acceleration and the peak acceleration producing the maximum relative density is proportional to the difference between maximum and minimum void ratios. It is also found that the effect of surcharge loading : the greater the surcharge loading, the larger the change in relative density and the greater the acceleration required to change the relative density.

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Study on Characteristics of SCC and AE Signals for Weld HAZ of HT-60 Steel (HT-60강 용접부의 SCC및 AE신호특성에 관한 연구)

  • Na, Eui-Gyun;Yu, Hyo-Sun;Kim, Hoon
    • Journal of the Korean Society for Nondestructive Testing
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    • v.21 no.1
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    • pp.62-68
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    • 2001
  • In order to characterize the microscopic fracture behaviour of the weldment din stress corrosion cracking(SCC) phenomena, SCC and acoustic emission(AE) tests were carried out simultaneously and the correlation between mechanical paramenters obtained from SCC and AE tests was investigated. In the case of base metal, much more AE events were produced at -0.5V than at -0.8V because of the dissolution mechanism before the maximum load. Regardless of the applied voltages to the specimens, however, AE events decreased after the maximum load. In the case of weldment, lots of AE events with larger amplitude $range(40{\sim}100dB)$ were produced because of the singularities of weld HAZ in comparision to the base metal and post-weld heat-treated(PWHT) specimens. Numerous and larger cracks for the weldment were observed on the fractured surfaces by SEM examination. From these results, it was concluded that SCC for the weldment appeared most severely in synthetic seawater. Weld HAZ was softened by PWHT which also contributed to the reduced susceptibility to corrosive environment in comparison to the weldment.

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