• 전자공학회논문지CI
• /
• 제40권4호
• /
• pp.193-205
• /
• 2003

지능 제어, 통신, 컴퓨터 및 센서 기술, 영상 처리, 메카트로닉스 등과 같은 다양한 분야에서 로봇 축구 시스템에 대한 연구가 진행되고 있다. 그중 전략 연구는 대부분 공격 전략 연구에 치중하고 있으며, 점차 지능적인 공격 전략을 구현하는 방향으로 흘러가고 있다. 이에 따라 과거의 단순한 수비 전략으로는 완전한 수비가 불가능하게 되었다. 따라서, 지능적인 공격을 효율적으로 수비할 수 있는 수비 전략이 필요하며, 효율적인 수비를 위하여 공격자 로봇의 의도 추출이 필요하다. 본 논문에서는, 퍼지 최대 최소 신경망을 이용한 축구 로봇의 공격 의도 추출기를 설계하였다. 첫째로 축구 로봇 시스템에서의 의도를 정의하고 의도 추출에 대하여 설명한다. 다음으로 설계한 퍼지 최대 최소 신경망을 이용하여 설계한 축구 로봇의 의도 추출기에 대하여 설명한다. 퍼지 최대 최소 신경망은 패턴분류 방법 중의 하나로 온라인 적용, 짧은 학습 시간, 소프트 결정(soft decision) 등의 많은 장점을 갖고 있다. 따라서, 다이나믹한 환경을 가진 축구 로봇 시스템의 의도 추출에 적합하다. 이 의도 추출기는 상대 팀 로봇이 공격시 어떠한 상황에서 어떠한 행동을 할 것인가를 미리 알아내어 수비 시 이용할 수 있도록 하며, 학습을 통하여 의도 추출을 함으로써 상대 팀 경기를 보고 팀의 전략을 파악하는 전략 분석기로도 사용이 가능하다. 자체 제작한 3대3 로봇 축구 시뮬레이터를 이용하여 시뮬레이션을 하였으며, 학습을 함에 따라서 의도 추출률이 증가함을 확인할 수 있었다.

• 한국전자파학회논문지
• /
• 제22권11호
• /
• pp.1078-1091
• /
• 2011

본 논문은 스파이럴 공진기(spiral resonators)와 CSRR(Complementary Split Ring Resonator)를 이용하여 삼중 대역 저지 특성을 갖는 UWB 안테나를 두 가지 타입으로 제안하였다. 제안된 안테나의 대역 저지 특성 분석을 위해 스파이럴 공진기와 CSRR의 구조 및 등가 회로를 통해 해석하였다. 첫 번째 타입의 안테나의 측정 결과는 1.16~12 GHz에서 VSWR<2 이하를 만족하였고, 3.3~3.85 GHz, 5.15~6.1 GHz, 8.025~8.5 GHz에서 대역 저지 특성이 나타났다. 두 번째 타입 안테나의 측정 결과는 1.79~12 GHz에서 VSWR<2 이하를 만족하였고, 3.3~3.88 GHz, 5.12~5.94 GHz, 8.025~8.51 GHz에서 대역 차단 특성이 나타났다. 측정결과를 통해 제안된 안테나는 노치대역을 제외하고 UWB 전 대역을 만족하였다.

• 생물환경조절학회지
• /
• 제12권4호
• /
• pp.200-206
• /
• 2003

본 연구에서는 새송이버섯을 중심으로 품질향상 및 생산량 증대를 목적으로 적정재배사의 구조설계 및 환경조절 기술을 개발 ${\cdot}$ 보급하기 위하여 서부 경남지역의 새송이버서 재배농가를 중심으로 재배사의 구조 및 환경조절장치를 조사하였다. 또한 환경조절실태를 조사하기 위하여 농가에 위치한 2개 동의 상업용 버섯재배사를 대상으로 환경인자를 계측하였다. 본 연구에서는 이들 연구 중 환경인자 계측결과를 분석하였다. 실험기간동안 외기온은 평년과 큰 차이가 없었으나, 재배사 내부의 온도가 설정온도보다 다소 낮게 유지되고 있기 때문에 진주지역의 동절기 최저 외기온을 고려하면, 난방기 용량이나 배관에 문제가 있는 것으로 판단되었다. 난방 시 상하 재배상간 온도차가 최대 2~3$^{\circ}C$ 정도로 높게 나타나 높이별 온도분포가 일정하지 않을 뿐만 아니라 또 최하단 재배상에서 균상이 지나치게 건조하게 되어 버섯의 발이가 잘 되지 않는 등의 문제도 종종 발생하였다. 그리고 상대습도는 재배 기간 동안 변화가 심하고, 평균상대습도도 일반적으로 알려져 인ㅅ는 것보다 발이기나 생육기에 모두 다소 높거나 낮게 유지되는 등 습도유지가 일정하지 않은 것을 알 수 있었다. 탄산가스 농도도 권장농도보다 높게 유지되는 등이 문제가 있었다. 조도는 권장조도보다 전반적으로 낮게 유지되고 있음을 알 수 있었다. 또한 버섯의 수확량은 평균적으로 병당 약 67~85 g 정도로 나타났고, 총 판매금액은 균상 구입비의 2배 이사인 것으로 조사되었다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권8호
• /
• pp.4119-4123
• /
• 2012

Background: Neoadjuvant systemic chemotherapy is the accepted approach for women with locally advanced breast cancer. Anthracycline- and taxane-based regimens have been extensively studied in clinical trials and consequently are widely used. In this study aimed to research the complete response (pCR) rates in different regimens for neoadjuvant setting and determine associated clinical and biological factors. Methods: This study included 63 patients diagnosed with breast carcinoma among 95 patients that had been treated with neoadjuvant chemotherapy between 2007 and 2010. TNM staging system was used for staging. The histologic response to neoadjuvant chemotherapy was characterized as a pCR when there was no evidence of residual invasive tumor in the breast or axillary lymph nodes. Biologic subclassification using estrogen receptor (ER), progesterone receptor (PR), HER2 were performed. Luminal A was defined as ER+, PR+, HER2-; Luminal B tumor was defined as ER+, PR-, HER2-; ER+, PR-, HER2+; ER-, PR+, HER2-; ER+, PR+, HER2+; HER2 like tumor ER-, PR+, HER2+; and triple negative tumor ER, PR, HER2 negative. Results: Patients median age was 54.14 (min-max: 30-75). Thirty-two patients (50.8%) were premenapousal and 31 (49.2%) were postmenapousal. Staging was performed postoperatively based on the pathology report and appropriated imaging modalities The TNM (tumor, lymph node, metastasis) system was used for clinical and pathological staging. Fifty-seven (90.5%) were invasive ductal carcinomas, 6 (9.5%) were other subtypes. Thirty nine (61.9%) were grade II and 24 (38.1%) were grade III. Seven (11.1%) patients were stage II and 56 (88.9) patients were stage III. The patients were classified for ER, PR receptor and HER2 positivity. Seventeen patients had complete response to chemotherapy. Forty patients (63.5%) were treated with dose dense regimen (cyclophosphamide 600 mg/m2 and doxorubicine 60 mg/m every two weeks than paclitaxel 175 mg/m2 every two weeks with filgrastim support) 40 patients (48%) were treated anthracycline and taxane containing regimens. Thirteen patients (76%) from 17 patients with pCR were treated with the dose dense regimen but without statistical significance (p=0.06). pCR was higher in HER2(-), ER(-), grade III, premenopausal patients. Conclusion: pCR rate was higher in the group that treated with dose dense regimen, which should thus be the selected regimen in neoadjuvant setting. Some other factors can predict pCR in Turkish patients, like grade, menopausal status, triple negativity, percentage of ER positivity, and HER2 expression.

• 기본간호학회지
• /
• 제6권3호
• /
• pp.493-506
• /
• 1999

The purpose of the study is to evaluate the effectiveness and competence level of trainees of Cardiopulmonary resuscitation training targeted for nursing students. 70 nursing students of Y nursing college are recruited as subjects from Dec. 1st, 1998 through Dec. 8th. 1998. For the pre-test. demographic data related to CPR and knowledge of CPR were evaluated. For the post-test, the next week of pre-test, three difference groups of subjects were tested their knowledge of CPR. CPR training was designed by two components which were 90 mins lecture and demonstration by one professor and individual practice using two educational models with two professors. As the tool of measurement estimating pre or post knowledge of CPR. questionnaires were developed based on self-diagnosis questionnaires of American Heart Association(AHA). The questionnaires were multiple choices (50 questions) and open end questions regarding CPR process. Each multiple choices questions valued 2 points (Score varied min. 0 point to max 100 points.). Collected data were computerized and analyzed by SPSS-WIN. Frequency and percentage of each questions analyzed. The differences of the knowledge and competency level of subjects between pre and post test was analyses by paired t-test. The followings are research outcome. 1. In the pre-test, 95% of subjects answered that they already knew what CPR was. but only 82% described correctly what CPR was. 49% learned CPR before, and 80s5 of them learned at high school. 2. 37 questions scores increases, and 10 questions scores decreased. 3 questions didnt change their score. After getting training, ratio of 80% correct score significantly increased 4 times. 3. In post-test. knowledge level of trainees increased compared to that of pre-test. (t=-15.075, p=.000) 4. Competence level also increased (t=-14.86, p=.00). In result, after getting CPR training, most CPR knowledge increased except open the air tract, toddler CPR, and alternative behavior when the air tract is blocked. CPR training needs to extend the educational scope not only CPR lecture but also psychomotor skill practice. CPR trainees are in need of appropriate feedback as well as enough opportunities of skill practice.

• 환경정책연구
• /
• 제10권1호
• /
• pp.27-47
• /
• 2011

단독주택지의 도시환경보전 및 개선을 위해 서울시 강남구 수서동 일원의 단독주택지 밀집지역을 대상으로 생태 면적률 개념을 적용한 비오톱 유형화와 도시열환경 예측 시뮬레이션을 실시하였다. 생태면적률 개념을 적용하여 비오톱 유형 분류 결과 총 7개 유형으로 구분되었고 옥상녹화 미적용 건폐지비오톱(48.16%) > 불투수비건폐포장비오톱(39.75%) > 전면투수녹지비오톱(6.23%) > 틈새투수비건폐포장비오톱(3.26%) > 전면투수비건폐포장지비오톱(2.51%) > 부분투수비건폐포장지비오톱(0.04%) 순이었다. 단독주택지 외부 열환경 특성 및 변화 예측을 실시한 결과, 비오톱 유형별 지표면 온도값은 불투수비건폐포장지비오톱 > 옥상녹화미적용건폐지비오톱 > 전면투수녹지비오톱 > 투수포장지비오톱이 순이었다. 옥상녹화 100% 적용을 가정한 case 2의 경우 최대 $33.58^{\circ}C$, 최소 $23.85^{\circ}C$였고, 평균 $27.74^{\circ}C$로서 옥상녹화 전에 비해 약 $5.19^{\circ}C$ 감소한 것으로 예측되었다. 평균 외기온도는 case 2가 case 1보다 약 $0.18^{\circ}C$ 낮게 분석되었다.

• BMB Reports
• /
• 제36권6호
• /
• pp.545-551
• /
• 2003

A cDNA of bovine brain glutamate dehydrogenase (GDH) was isolated from a cDNA library by recombinant PCR. The isolated cDNA has an open-reading frame of 1677 nucleotides, which codes for 559 amino acids. The expression of the recombinant bovine brain GDH enzyme was achieved in E. coli. BL21 (DE3) by using the pET-15b expression vector containing a T7 promoter. The recombinant GDH protein was also purified and characterized. The amino acid sequence was found 90% homologous to the human GDH. The molecular mass of the expressed GDH enzyme was estimated as 50 kDa by SDS-PAGE and Western blot using monoclonal antibodies against bovine brain GDH. The kinetic parameters of the expressed recombinant GDH enzymes were quite similar to those of the purified bovine brain GDH. The $K_m$ and $V_{max}$ values for $NAD^+$ were 0.1 mM and $1.08\;{\mu}mol/min/mg$, respectively. The catalytic activities of the recombinant GDH enzymes were inhibited by ATP in a concentration-dependent manner over the range of 10 - $100\;{\mu}M$, whereas, ADP increased the enzyme activity up to 2.3-fold. These results indicate that the recombinant-expressed bovine brain GDH that is produced has biochemical properties that are very similar to those of the purified GDH enzyme.

• Journal of Mechanical Science and Technology
• /
• 제18권5호
• /
• pp.770-779
• /
• 2004

This paper describes the micro cutting of wear resistant tungsten carbides using PCD (Poly-Crystalline Diamond) cutting tools in performance with SEM (Scanning Electron Microscope) direct observation method. Turning experiments were also carried out on this alloy (V50) using a PCD cutting tool. One of the purposes of this study is to describe clearly the cutting mechanism of tungsten carbides and the behavior of WC particles in the deformation zone in orthogonal micro cutting. Other purposes are to achieve a systematic understanding of machining characteristics and the effects of machining parameters on cutting force, machined surface and tool wear rates by the outer turning of this alloy carried out using the PCD cutting tool during these various cutting conditions. A summary of the results are as follows: (1) From the SEM direct observation in cutting the tungsten carbide, WC particles are broken and come into contact with the tool edge directly. This causes tool wear in which portions scrape the tool in a strong manner. (2) There are two chip formation types. One is where the shear angle is comparatively small and the crack of the shear plane becomes wide. The other is a type where the shear angle is above 45 degrees and the crack of the shear plane does not widen. These differences are caused by the stress condition which gives rise to the friction at the shear plane. (3) The thrust cutting forces tend to increase more rapidly than the principal forces, as the depth of cut and the cutting speed are increased preferably in the orthogonal micro cutting. (4) The tool wear on the flank face was larger than that on the rake face in the orthogonal micro cutting. (5) Three components of cutting force in the conventional turning experiments were different in balance from ordinary cutting such as the cutting of steel or cast iron. Those expressed a large value of thrust force, principal force, and feed force. (6) From the viewpoint of high efficient cutting found within this research, a proper cutting speed was 15 m/min and a proper feed rate was 0.1 mm/rev. In this case, it was found that the tool life of a PCD tool was limited to a distance of approximately 230 m. (7) When the depth of cut was 0.1 mm, there was no influence of the feed rate on the feed force. The feed force tended to decrease, as the cutting distance was long, because the tool was worn and the tool edge retreated. (8) The main tool wear of a PCD tool in this research was due to the flank wear within the maximum value of $V_{max}$ being about 260 $\mu\textrm{m}$.

• 대한핵의학회지
• /
• 제33권2호
• /
• pp.163-171
• /
• 1999

목적 : 혈관 재협착을 막기 위하여 풍선에 용액 형태의 베타 방출 핵종을 넣어 사용하는 방법이 연구되고 있다. 이 연구에서는 Re-188-DTPA를 풍선에 넣어 사용하는 경우 주위 혈관에 대한 에너지 분포와 용액이 풍선에서 누출되는 경우 주요 장기와 전신에의 흡수 선량을 계산하였다. 대상 및 방법: 전자와 광자의 물에서의 운반은 몬테카를로 EGS4 코드를 사용하였으며 풍선은 직경 3 mm, 길이 20 mm의 원기둥으로 대체하였다. 개에게 Re-188-DTPA 370MBq를 주사하여 감마카메라로 영상을 얻어 주요장기의 잔류 시간을 구하였고 전신과 주요 장기에의 흡수 선량은 MIRDOSE3와 ICRP Dynamic Bladder모델을 사용하여 계산하였다. 결과: 3,700 MBq/1ml을 100초 동안 조사하였을 때 풍선 표면에 전달된 에너지는 17.6 Gy, 표면으로부터 0.5 mm 떨어진 곳에서 9.5 Gy이었다. 풍선에서 용액이 누출되었을 경우 전신에 0.005 mGy/MBq, 방광에 2.39 mGy/MBq의 흡수 선량이 전달되었다. 결론: 관상동맥 풍선 성형술용 풍선에 Re-188-DTPA를 주입하여 사용하는 방법이 목표선량을 조사하는 데 적절하고 방사선 안전의 관점에서 사용 가능한 방법이라고 생각한다.

• 한국미생물·생명공학회지
• /
• 제24권1호
• /
• pp.9-18
• /
• 1996

Streptococcus mutans has been implicated as primary causative agents of dental caries by insoluble glucan (IG) in human and experimental animals. An attempt was made to search for the ${\alpha}$-1,3 glucanase that degrades IG produced by S. mutans. ${\alpha}$-1,3 glucanase was detected in the culture supernatant of microorganisms, which are isolated from soils on agar medium containing IG as a sole carbon source. This Streptomyces sp. hydrolysed IG produced by immobilized S. mutans and was named as Y9373. This enzyme required ${\alpha}$-1,3 glucan (IG) as an inducer. The optimum conditions for enzyme production were studied. The enzyme was purified by 30~70% $(NH_4)_2SO_4$ precipitation, anion exchange chroma tography on DEAE-cellulose and gel filtration on Sepadex G-75. The purified enzyme has a specific activity of 7840.0 U/mg protein giving 32.1-fold purification and final yield of 0.53%. The molecular weight was estimated to be about 22.5 kDa by SDS-PAGE. The optimum pH and temperature for enzyme reaction were 6.5 and 37$^{\circ}C$, respectively and the enzyme was relatively stable at the temperature below 60$^{\circ}C$. The activity of purified enzyme was enhanced by adding $Co^{2+},\;Mn^{2+}\;and\;Mg^{2+}$ into the medium, whereas inhibited by adding $Hg^{2+},\;Zn^{2+}$ and SDS. The $K_m\;and\;V_{max}$ value of ${\alpha}$-1,3 glucanase for IG were estimated to be 2.50 mM and 0.0431 mM/min, respectively. The thin layer chromatographic analysis of hydrolysates from IG with ${\alpha}$-1,3 glucanase showed that glucose was the main product of reaction. This enzyme activity was about 14 times higher than marketing dextranase as preventive agent against artificial dental caries by S. mutans in TH medium including 5% sucrose after 30 minutes.