• Clinical and Experimental Pediatrics
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• v.48 no.6
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• pp.580-587
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• 2005

New evidence is emerging that airway smooth muscle(ASM) may act as an immunomodulatory cell by providing pro-inflammatory cytokines and chemokines, polypeptide growth factors, extracellular matrix proteins, cell adhesion receptors and co-stimulatory molecules. ASM can promote the formation of the interstitial extracellular matrix, and potentially contribute to the alterations within the extracellular matrix in asthma. In addition, extracellular matrix components can alter the proliferative, survival, and cytoskeletal synthetic function of ASM cells through integrin-directed signaling. Increased ASM mass is one of the most important features of the airway wall remodeling process in asthma. Three different mechanisms may contribute to the increased ASM mass : cell proliferation, increased migration and decreased rate of apoptosis. The major signaling pathways of cell proliferation activated by ASM mitogens are those dependent on extracellular signal-regulated kinase and phosphoinositide 3'-kinase. The key signaling mechanisms of cell migration have been identified as the p38 mitogen-activated protein kinase and the p21-activated kinase 1 pathways. ASM cells contain ${\beta}2$-adrenergic receptors and glucocorticoid receptors. They may represent a key target for ${\beta}2$-adrenergic receptor agonist/corticosteroid interactions which have antiproliferative activity against a broad spectrum of mitogens.

• Journal of the Korean Operations Research and Management Science Society
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• v.22 no.3
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• pp.113-143
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• 1997

Most of the conflict problems between 2 persons can be represented as a bi-matrix game, because player's utilities, in general, are non-zero sum and change according to the progress of game. In the bi-matrix game the equilibrium point set which satisfies the Pareto optimality can be a good bargaining or coordination solution. Under the condition of incomplete information about the risk attitudes of the players, the bargaining or coordination solution depends on additional elements, namely, the players' methods of making inferences when they reach a node in the extensive form of the game that is off the equilibrium path. So the investigation about the players' inference type and its effects on the solution is essential. In addition to that, the effect of an individual's aversion to risk on various solutions in conflict problems, as expressed in his (her) utility function, must be considered. Those kinds of incomplete information make decision maker Bayesian, since it is often impossible to get correct information for building a decision making model. In Baysian point of view, this paper represents an analytic frame for guessing and learning opponent's attitude to risk for getting better reward. As an example for that analytic frame. 2 persons'bi-matrix game is considered. This example explains that a bi-matrix game can be transformed into a kind of matrix game through the players' implicitly cooperative attitude and the need of arbitration.

• Journal of Biomedical Engineering Research
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• v.16 no.1
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• pp.1-8
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• 1995

A variety of experiments of endothelial cell seeding onto artificial vessels have been performed. To improve endothelialization, one or two components of the extracellular matrix (ECM) have been used as an underlying matrix. In this study, the whole ECM excreted from fibroblasts was used as an underlying matrix. Fetal human fibroblasts were cultured on a polyurethane (PU) sheet. After a conflu; ence was attained, the cytoskeleton and the nuclei of the fibroblast were destroyed using Triton-X. Mitomycin, or irradiation. Omental microvascular endothelial cells from adult human were seeded onto various substrates. After 12 days in culture, the cells were counted. It was observed that the ECM treated by irradiation had the highest cell number. In addition, the cells on this substrate exhibited the most typical endothelial cell morphology. For preliminary animal experiments the PU vessels (inner diameter, 1.5mm) coated with ECM were implanted in the infrarena] abdominal aorta of rat. After the vessels had been implanted for 5 weeks, it was found that the surface of the PU vessels was completely covered with endothelia] cells. In conclusion, we can state that the fibroblast-derived whole ECM makes a better underlying substrate for the endothelialization of small diameter artificial vessels.

• Proceedings of the KIEE Conference
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• 1989.07a
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• pp.233-236
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• 1989

This paper deals with the expert system using network configuration and input information composed of protective relays and tripped circuit breakers. This system has knowlegebase independent on network dimension because network representation consists of the type of the matrix. Therefore, the knowlege of network representation is simplified, the space of knowlege is reduced, the addition of facts to the knowlege is easy and the expansion of facts is possible. In this paper, the network representation is defined to system matrix. This expert system based on the system matrix diagnoses normal, abnormal operations of protective devices as well as possible fault sections. The brach and bound search technique is used: breadth first technique mixed with depth first technique of primitive PROLOG search technique. This system will be used for real time operations. This expert system obtaines the solution using the pattern matching in working memory without no listing approach for rule control. This paper is written in PROLOG, the A.I. language.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.9
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• pp.1081-1087
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• 1999

Load Flow calulation methods can usually be divided into Gauss-Seidel method, Newton-Raphson method and decoupled method. Load flow calculation is a basic on-line or off-line process for power system planning. operation, control and state analysis. These days Newton-Raphson method is mainly used since it shows remarkable convergence characteristics. It, however, needs considerable calculation time in construction and calculation of inverse Jacobian matrix. In addition to that, Newton-Raphson method tends to fail to converge when system loading is heavy and system has a large R/X ratio. In this paper, matrix equation is used to make algebraic expression and then to slove load flow equation and to modify above defects. And it preserve P-Q bus part of Jacobian matrix to shorten computing time. Application of mentioned algorithm to 14 bus, 39 bus, 118 bus systems led to identical results and the same numbers of iteration obtained by Newton-Raphson method. The effect of computing time reduction showed about 28% , 30% , at each case of 39 bus, 118 bus system.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2014.10a
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• pp.288-291
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• 2014

MRE(Magneto-rheological Elastomer) is a material which shows reversible and various modulus in magnetic field. Comparing to conventional rubber vibration isolator, MREs are able to absorb broader frequency range of vibration. These characteristic phenomena result from the orientation of magnetic particle (i.e., chain-like formation) in rubber matrix. In this study, Silicon was used as a matrix in order to manufacture MREs. Magnetic reactive powder(MRP), having rapid magnetic reaction, was selected as a magnetic particle to give magnetic field reactive modulus. The mechanical properties of manufactured MREs were measured with the application of magnetic field. The analysis of MR effect was carried out by FFT analyzer with various induced magnetic field. As the addition of CIP and induced magnetic field intensity increased, increment of MR effect was observed.

• Journal of Korea Foundry Society
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• v.13 no.6
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• pp.524-531
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• 1993

Dispersion behaviors of SiC particles and microstructures in Al-2%Si/SiCp composite prepared by Rheo-compocasting were studied with change of fabrication conditions(slurry temperature, agitation time) and additions of Mg($0{\sim}3wt.%$). Also, the microhardness change of matrix, interface and total in composites were examined with additions of Mg($0{\sim}3wt.%$). The dispersion of particles in the composites became relatively homogeneous with increase of Mg additions, agitation time and decrease of slurry temperature. Rate of occupied area by particle in matrix was increased as increase of Mg additions due to improvement of wettability between SiC particle and matrix. A favorable composites were obtained by melting under Ar atmospheric SiCp injection and bottom pouring system. According to the analysis of X-ray diffraction, $Mg_2Si$, $Al_4C_3$, $SiO_2$ and MgO, etc, intermetallic compounds were formed by chemical interreaction at interface of matrix and particles. The microhardness of interface is higher than that of matrix due to more strengthening of above intermetallic compounds. It was considered that the total hardness of the composites is improved by dispersing of SiCp and addition of Mg.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2007.04a
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• pp.421-426
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• 2007

A parametric study to investigate the effects of composition variables on the glass transition and mechanical properties of CNT-based nanocomposites was performed using molecular dynamics simulations. In this study, matrix chain length and CNT length were chosen as the candidate characteristic parameters. In order to understand the effect of both parameters in detail, three sample sets having different chain lengths with the same CNT configuration and two sample sets having different CNT lengths with same chain length were prepared. Other parameters such as volume fraction and density were fixed to enable rigorous comparisons. Amorphous polyethylene is used as matrix polymer and (10,0) zigzag CNT is embedded into the matrix to reinforce polymer matrix. As a result, longer polymer chain length of matrix solely increased glass transition temperature but no reinforcing enhancement was observed. CNT length showed similar increase with little enhancement of elastic modulus. In addition to this, nanocomposites showed temperature-dependent elastic modulus jump passing thorough the glass transition region agrees well with experimental results.

• Journal of Power Electronics
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• v.17 no.4
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• pp.991-1003
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• 2017

The conventional sliding mode control (CSMC) has a number of problems. It may cause dc output voltage ripple and it cannot guarantee the robustness of the whole system for a matrix rectifier (MR). Furthermore, the existence of a filter can decrease the input power factor (IPF). Therefore, a novel global sliding mode control (GSMC) based on a hyperbolic tangent function with IPF compensation for MRs is proposed in this paper. Firstly, due to the reachability and existence of the sliding mode, the condition of the matrix rectifier's robustness and chattering elimination is derived. Secondly, a global switching function is designed and the determination of the transient operation status is given. Then a SMC compensation strategy based on a DQ transformation model is applied to compensate the decreasing IPF. Finally, simulations and experiments are carried out to verify the correctness and effectiveness of the control algorithm. The obtained results show that compared with CSMC, applying the proposed GSMC based on a hyperbolic tangent function for matrix rectifiers can achieve a ripple-free output voltage with a unity IPF. In addition, the rectifier has an excellent robust performance at all times.

• The Journal of the Korea institute of electronic communication sciences
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• v.14 no.4
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• pp.729-736
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• 2019

In this paper, we propose a method to improve the background sound separation performance by adding a Wiener filter to the end of the non - negative matrix factorization method. In the case of a mixed voice signal with background sound, a part that has not yet been completely separated may remain in the signal that separated first by the non-negative matrix factorization method. In this case, it can be reduced in proportion to the size of the residual signal due to the Wiener filter, so that the background sound separation or reduction effect can be expected. Experimental results show that the addition of the Wiener filter is more effective than the case of applying the non-negative matrix factorization method.