• Korean Journal of Radiology
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• v.24 no.7
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• pp.647-659
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• 2023

Objective: The study was conducted to investigate the effect of correct occlusion of the left atrial appendage (LAA) on intracardiac blood flow and thrombus formation in patients with atrial fibrillation (AF) using four-dimensional (4D) flow magnetic resonance imaging (MRI) and three-dimensional (3D)-printed phantoms. Materials and Methods: Three life-sized 3D-printed left atrium (LA) phantoms, including a pre-occlusion (i.e., before the occlusion procedure) model and correctly and incorrectly occluded post-procedural models, were constructed based on cardiac computed tomography images from an 86-year-old male with long-standing persistent AF. A custom-made closed-loop flow circuit was set up, and pulsatile simulated pulmonary venous flow was delivered by a pump. 4D flow MRI was performed using a 3T scanner, and the images were analyzed using MATLAB-based software (R2020b; Mathworks). Flow metrics associated with blood stasis and thrombogenicity, such as the volume of stasis defined by the velocity threshold ($\left|\vec{V}\right|$ < 3 cm/s), surface-and-time-averaged wall shear stress (WSS), and endothelial cell activation potential (ECAP), were analyzed and compared among the three LA phantom models. Results: Different spatial distributions, orientations, and magnitudes of LA flow were directly visualized within the three LA phantoms using 4D flow MRI. The time-averaged volume and its ratio to the corresponding entire volume of LA flow stasis were consistently reduced in the correctly occluded model (70.82 mL and 39.0%, respectively), followed by the incorrectly occluded (73.17 mL and 39.0%, respectively) and pre-occlusion (79.11 mL and 39.7%, respectively) models. The surfaceand-time-averaged WSS and ECAP were also lowest in the correctly occluded model (0.048 Pa and 4.004 Pa^-1, respectively), followed by the incorrectly occluded (0.059 Pa and 4.792 Pa^-1, respectively) and pre-occlusion (0.072 Pa and 5.861 Pa^-1, respectively) models. Conclusion: These findings suggest that a correctly occluded LAA leads to the greatest reduction in LA flow stasis and thrombogenicity, presenting a tentative procedural goal to maximize clinical benefits in patients with AF.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.37 no.3
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• pp.307-312
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• 2013

The interest in reducing the emissions and increasing the fuel economy of ICE vehicles has prompted research on hybrid vehicles, which come in the series, parallel, and power-split types. This study focuses on the series-type hybrid electric vehicle, which has a simple structure. Because each component of a series hybrid vehicle is larger than the corresponding component of the parallel type, the sizing of the vehicle is very important. This is because the performance may be greater or less than what is required. Thus, in this research, the optimal fuel economy was determined and simulated in a real-world system. The optimal sizing was achieved based on the motor, engine/generator, and battery for 13 cycles, where DP was used. The model was developed using ASCET or a Simulink-Amisim Co-simulation platform on the rapid controller prototype, ES-1000.

• Journal of Institute of Control, Robotics and Systems
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• v.17 no.11
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• pp.1117-1124
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• 2011

An integrated fault detection and isolation method is proposed in this paper. The main objective of this paper is development fault detection, isolation and diagnosis algorithm based on the DKF (Decentralized Kalman Filter) and the bank of IMM (Interacting Multiple Model) filters using penalty scalar for both partial and total faults and the outlier detection algorithm for preventing false alarm also included. The proposed FDI (Fault Detection and Isolation) scheme is developed in four phases. In the first phase, the outlier detection filter is designed to prevent false alarm as a pre-filter. In the second phases, two local filters and master filter are designed to detect sensor faults. In the third phases, the proposed FDI scheme checks sensor residual to isolate sensor faults and 11 EKFs actuator fault models are designed to detect wherever actuator faults occur. In the last phases, four filters are designed to identify the fault type which is either the total fault or partial fault. The developed scheme can deal with not only sensor and actuator faults, but also preventing false alarm. An important feature of the proposed FDI scheme can decreases fault isolation time and figure out not only fault detection and isolation but also fault type identification. To verify the proposed FDI algorithm performance, the Simulator is also developed under the Matlab/Simulink environment.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2008.04a
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• pp.397-401
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• 2008

Knowledge of dynamic characteristics of structural elements often can make difference between success and failure in the design of structure due to resonance effect. In this paper an analytical model of a cantilever beam having midpoint load is considered for structural optimization. This involves creating the geometry which allows parametric study of all design variables. For that purpose optimization of cantilever beam is elaborated in order to find the optimum geometry which minimizes its volume eventually for minimum weight using ANSYS. But such geometry could be obtained by different combinations of width and height, so that it may have the same cross sectional area yet different dynamic behavior. So for optimum safe design, besides minimum volume it should have minimum vibration as well. In order to predict vibration different dynamic analyses are performed simultaneously to solve the eigenvalues problem assuming no damping initially through MATLAB simulations using state space form for modal analysis, which identifies the resonant frequencies and mode shapes belonging to the lowest three modes of vibration. And next by introducing damping effects tip displacement, bending stress and the vertical reaction force at the fixed end is evaluated under some dynamic load of varying frequency, and finally it is discussed how resonance can be avoided for particular design. Investigation of results clearly shows that only structural analysis is not enough to predict the optimum values of dimension for safe design. Potentially this technique will meet maintenance and cost goals of many organizations particularly for the application where dynamic loading is invertible and helps a lot ensuring that the proposed design will be safe for both static and dynamic conditions.

• Geomechanics and Engineering
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• v.14 no.6
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• pp.589-600
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• 2018

For foundations in permafrost regions, the displacement characteristics are uncertain because of the randomness of temperature characteristics and mechanical parameters, which make the structural system have an unexpected deviation and unpredictability. It will affect the safety of design and construction. In this paper, we consider the randomness of temperature characteristics and mechanical parameters. A stochastic analysis model for the uncertain displacement characteristic of foundations is presented, and the stochastic coupling program is compiled by Matrix Laboratory (MATLAB) software. The stochastic displacement fields of an embankment in a permafrost region are obtained and analyzed by Neumann stochastic finite element method (NSFEM). The results provide a new way to predict the deformation characteristics of foundations in permafrost regions, and it shows that the stochastic temperature has a different influence on the stochastic lateral displacement and vertical displacement. Construction disturbance and climate warming lead to three different stages for the mean settlement of characteristic points. For the stochastic settlement characteristic, the standard deviation increases with time, which imply that the results of conventional deterministic analysis may be far from the true value. These results can improve our understanding of the stochastic deformation fields of embankments and provide a theoretical basis for engineering reliability analysis and design in permafrost regions.

• Journal of Oral Medicine and Pain
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• v.41 no.3
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• pp.85-90
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• 2016

Purpose: The aim of this study was to develop an automated software to extract tooth and pulpal area from sectional cone-beam computed tomography (CBCT) images, which can guarantee more reproducible, objective and time-saving way to measure pulp/tooth volume ratio. Methods: The software program was developed using MATLAB (MathWorks). To determine the optimal threshold for the region of interest (ROI) extraction, user interface to adjust the threshold for extraction algorithm was added. Default threshold was determined after several trials to make the outline of extracted ROI fitting to the tooth and pulpal outlines. To test the effect of starting point location selected initially in the pulpal area on the final result, pulp/tooth volume ratio was calculated 5 times with different 5 starting points. Results: Navigation interface is composed of image loading, zoom-in, zoom-out, and move tool. ROI extraction process can be shown by check in the option box. Default threshold is adjusted for the extracted tooth area to cover whole tooth including dentin, cementum, and enamel. Of course, the result can be corrected, if necessary, by the examiner as well as by changing the threshold of density of hard tissue. Extracted tooth and pulp area are reconstructed three-dimensional (3D) and pulp/tooth volume ratio is calculated by voxel counting on reconstructed model. The difference between the pulp/tooth volume ratio results from the 5 different extraction starting points was not significant. Conclusions: In further studies based on a large-scale sample, the most proper threshold to present the most significant relationship between age and pulp/tooth volume ratio and the tooth correlated with age the most will be explored. If the software can be improved to use whole CBCT data set rather than just sectional images and to detect pulp canal in the original 3D images generated by CBCT software itself, it will be more promising in practical uses.

• Advances in nano research
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• v.9 no.1
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• pp.1-13
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• 2020

In this work, the electrical potential (EP) technique with an artificial neural networks (ANNs) for monitoring of nanostructures are used for the first time. This study employs an expert system to identify size and localize hidden nano-delamination (N.Del) inside layers of nano-pipe (N.P) manufactured from Basalt Fiber Reinforced Polymer (BFRP) laminate composite by using low-cost monitoring method of electrical potential (EP) technique with an artificial neural networks (ANNs), which are combined to decrease detection effort to discern N.Del location/size inside the N.P layers, with high accuracy, simple and low-cost. The dielectric properties of the N.P material are measured before and after N.Del introduced using arrays of electrical contacts and the variation in capacitance values, capacitance change and node potential distribution are analyzed. Using these changes in electrical potential due to N.Del, a finite element (FE) simulation model for N.Del location/size detection is generated by ANSYS and MATLAB, which are combined to simulate sensor characteristic, therefore, FE analyses are employed to make sets of data for the learning of the ANNs. The method is applied for the N.Del monitoring, to minimize the number of FE analysis in order to keep the cost and save the time of the assessment to a minimum. The FE results are in excellent agreement with an ANN and the experimental results available in the literature, thus validating the accuracy and reliability of the proposed technique.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2000.11a
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• pp.452-455
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• 2000

There are increasingly important financial incentives and environmental consideration to improve the effluent quality of wastewater from domestic and industrial users. The activated sludge process is a widely used biological wastewater treatment process. The activated sludge process is complicated due to the many factors such as the variation of influent flowrate and concentration, the complexity of biological reactions and the various operation conditions. Nowadays, not only suspended solids and residual carbon, but also nitrogen and phosphorous concentration of the effluent water must be taken into account for the design and operation of wastewater treatment plants. Also, the effluent quality to be met are more stringent. Therefore, an intelligent control approach is required in order to successful biological nitrogen removal. In this paper, the strategies for dosage of extra carbon in the anoxic zone and DO concentration in the aerobic zone are presented and evaluated through the simulation using the denitrification layout of the IWA simulation benchmark implemented by Matlab$\^$/5.3/Simulink$\^$/3.0. The control strategy to achieve sufficient denitrification rates in an anoxic zone. Methanol is used as an external extra carbon source. The external extra carbon source is required for the nitrogen removal process because nitrogen and organic concentration are fluctuated in the influent flowrate. The dissolved oxygen is calculated by So concentration in the activated sludge model NO.1. The air flowrate of each aerobic reactor is intelligently controlled to achieve the predefined setpoints. Air flowrate is adjusted by the fuzzy logic controller that includes two inputs and one output. The objective function for the optimization procedure is designed to improve effluent quality and reduce the operating cost.

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.1
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• pp.14-22
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• 2010

Hybrid Electronic Vehicle (HEV) is one of the solutions of high oil price and environment problem. Recently, study of HEV is important for automobile industry. However HEV has a lot of components and there are many cases for assembling, it's impossible to test results from assembling by using real vehicles. To solve this problem, hybrid system simulator is required. The purpose of this study is to develop and optimize of engine module for hybrid system simulator. The commercial 1-D engine simulation program, WAVE is used to get the engine capacity and performance data and 1-D simulation model of base engine is compared with engine experiment results. Using the data, the engine module is developed based on the MATLAB Simulink. There are blocks of base engine, Single-CVVT engine and Dual-CVVT engine. The effect of acceleration and deceleration is applied to each engine block. In addition, the control and processing logics for CIS technology are developed. Finally the simulator operates FTP-72 mode test.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1906-1909
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• 2005

This paper presents the acceleration optimization of a high-speed LCD (Liquid Crystal Display) transfer system for the minimization of vibration. To reduce vibration is one of key requirements for the dynamic control of a high-speed LCD transfer system. In this paper, the concept of finite jerk (the first derivative of acceleration) has been introduced for realizing input acceleration. The profile of finite jerk has been optimized using a genetic algorithm so that vibration effect can be minimized. In order to incorporate a genetic algorithm, the dynamic model of a LCD transfer system which is realized by using the $ADAMS^{(R){$ software has been linked to the simulation system constructed by the $MATLAB^{(R)}$. The simulation results illustrated that the duration of finite jerk can be optimized so as to minimize the magnitude of vibration. It has been also shown that the acceleration optimization with finite jerk can make the high-speed motion of a LCD transfer system result in low vibration, compared with the conventional motion control with trapezoidal velocity profile.