• Journal of Pharmaceutical Investigation
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• v.38 no.2
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• pp.111-117
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• 2008

To overcome the solubility of poorly water-soluble drug, the formation of solid dispersion using a spray-dryer with polymeric material, that can potentially enhance the dissolution rate extend of drug absorption was considered in this study. $Eudragit^{(R)}$ E100 as carrier for solid dispersion is acrylate copolymer that soluble in acidic buffer solutions (below pH 5.0). It was used to increase dissolution of atorvastatin calcium as a water-insoluble drug in acidic environments. In this study, a spray-dryer was used to prepare solid dispersion of atorvastatin calcium and $Eudragit^{(R)}$ E100 for purpose of improving the solubility of drug. Atorvastatin calcium and $Eudragit^{(R)}$ E100 were dissolved in ethanol and spray-dryed. DSC and XRD were used to analyze the crystallinity of the sample. It was found that atorvastatin calcium is amorphous in the $Eudragit^{(R)}$ E100 solid dispersion. FT-IR was used to analyze the salt formation by interaction between atorvastatin calcium and $Eudragit^{(R)}$ E100. Comparative dissolution study exhibited better dissolution characteristics than the commercial drug ($Lipitor^{(R)}$) as control. The dissolution rate of atorvastatin calcium was markedly increased in solid dispersion system in simulated gastric juice (pH 1.2). This study proposed that this solid dispersion system improved the bioavailability of poorly water-soluble atorvastatin calcium.

• The Korean Journal of Food And Nutrition
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• v.25 no.3
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• pp.538-545
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• 2012

The objective of this work was to study the effect of far infrared ray-vacuum drying having reflection and dispersion functions(RD-FRVD) and hot air drying(HAD) on the quality changes of dried vegetable flakes. HAD was regarded as a control. Browning degrees, color value, titratable acidity and pH value were measured as chemical evaluations. Rehydration and electron micrographs were investigated as physical evaluation. Microbial cells were counted. The color value and browning degrees were increased in both RD-FRVE and HAD. In case of degree of those changes, RD-FRVD made less changes than HAD. Especially, green bean sprout had no differences in color value and browning degrees between raw material and dried-rehydrated material. There were no significance differences in titratable acidity and pH value between raw material and dried-rehydrated material. The total microbial counts were gradually reduced in RD-FRVD. The rehydration rates of dried vegetable flakes were typically increased in RD-FRVD. Also, these results were investigated electron micrographs evaluation. Therefore, these results showed that the quality of dried-rehydrated vegetable flakes was typically enhanced by using RD-FRVD.

• Transactions on Electrical and Electronic Materials
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• v.13 no.4
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• pp.196-199
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• 2012

CdS thin film was prepared on glass substrate by chemical bath deposition in an alkaline solution. The optical properties of CdS thin film were investigated using spectroscopic ellipsometry. The real (${\varepsilon}_1$) and imaginary (${\varepsilon}_2$) parts of the complex dielectric function ${\varepsilon}(E)={\varepsilon}_1(E)+i{\varepsilon}_2(E)$, the refractive index n(E), and the extinction coefficient k(E) of CdS thin film were obtained from spectroscopic ellipsometry. The normal-incidence reflectivity R(E) and absorption coefficient ${\alpha}(E)$ of CdS thin film were obtained using the refractive index and extinction coefficient. The critical points $E_0$ and $E_1$ of CdS thin film were shown in spectra of the dielectric function and optical constants of refractive index, extinction coefficient, normal-incidence reflectivity, and absorption coefficient. The dispersion of refractive index was analyzed by the Wemple-DiDomenico single-oscillator model.

• Journal of KSNVE
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• v.7 no.3
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• pp.449-455
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• 1997

A theoretical study is presented for the prediction of the scattering of obliquely incident plane acoustic wave by transversely isotropic cylindrical shells immersed in water. In dorder to illustrate the vailidity of the theory backscattering form functions are compared with the existing results for degenerated problems: the catterings by isotropic shell and transversely isotropic solid cylinder. The unidirectional fiber reinforced boron-aluminum composites are selected as a model of transversely isotropic materials having potential applications in practice. From the resonant scattering analysis of the partial backscattering form functions, the dispersion curves for fluid-borne Stoneley wave, guided wave along the shell, and the lowest three Lamb type waves can be found. The Lamb type dispersions are compared with those of the flat plate. The variation of anisotropy significantly affects the properties of circumferential waves. From these results, it can be possible to identify parametrically the material properties of anisotropic cylindrical targets.

• Structural Engineering and Mechanics
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• v.74 no.4
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• pp.547-557
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• 2020

In this paper, an automatic adaptive mesh refinement procedure is presented for two-dimensional problems on the basis of a new probabilistic error estimator. First-order perturbation theory is employed to determine the lower and upper bounds of the structural displacements and stresses considering uncertainties in geometric sizes, material properties and loading conditions. A new probabilistic error estimator is proposed to reduce the mesh dependency of the responses dispersion. The suggested error estimator neglects the refinement at the critical points with stress concentration. Therefore, the proposed strategy is combined with the classic adaptive mesh refinement to achieve an optimal mesh refined properly in regions with either high gradients or high dispersion of the responses. Several numerical examples are illustrated to demonstrate the efficiency, accuracy and robustness of the proposed computational algorithm and the results are compared with the classic adaptive mesh refinement strategy described in the literature.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.133-134
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• 2006

In contrast to paints, the surface appearance of adhesive materials is of minor importance, because the adhesive is invisible between the two substrates. Therefore, the rheological properties needed to apply an adhesive dispersion by spray coating can be quite different. The influence of three different kinds of thickeners on the spraying behaviour of polyurethane adhesive dispersions was investigated. The associative thickener showed only minor changes, whereas the higher molecular weight soluble thickeners dramatically changed the spraying angle and the amount of overspray. Determination of the elongational viscosity by means of the CaBER rheometer proved to be of limited use for thickened dispersions.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.33A no.7
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• pp.245-252
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• 1996

$\lambda$/4 phase-shifted DFB lasers with nonideal grating structure have been studied by using an effective-index transfer matrix method where material dispersion, vwaveguide dispersion and waveguide-structuredependent loss are taken into consideration. Nonideal grating structure in the center phase-shift region does not incur serous degradation of laser characteristics. Phase-shift error from the ideal shift of $\pi$ causes a decrease in the threshold gain difference and lasing wavelength shift and should be less than $\pi$/4 when residual facet reflectivity is 0.7%. also, positional error of the phase-shift should be less than 9% of the cavity length in order for the threshold gain difference to be decreased less than 10%.

• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.1378-1381
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• 2006

The CNTs are the most extensively studied material which are characterized by the complete property of matter, structure, and the large thermal conductivity (Thermal conductivity of $CNTs\;{\sim}>2000W/mK$ vs. Thermal conductivity of Aluminum ${\sim}\;>204W/mK$). Thus, they are successfully applied to the various fields. However, due to the strong agglomeration caused by the van der waal's force, their applications are limited. In the present study, a new method for CNTs dispersion was developed by using the mechanical dispersion, acid treatment, and then Cu was coated. This process produces CNTs/Cu nanocomposite powders, whereby the CNTs are homogeneously located within the Cu powders. The thermal properties of the CNTs/Cu nanocomposite were investigated.

• Electrical & Electronic Materials
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• v.8 no.3
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• pp.332-339
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• 1995

In this paper, it was investigated the guided field intensity distribution of the channel in the silver & potassium ion-exchange glass-waveguide. The guided field intensity distribution analysis of ion-exchange glass-waveguide was based on the combination of the WKB dispersion relationship method with a Gaussian distribution function of refractive index profile and the Field Shadow method to the modeling of the channel waveguide. As the results of the channel waveguide modeling, it was represented 2-dimensional and 3-dimensional field distribution of ion-exchange glass waveguide.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.49 no.3
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• pp.75-81
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• 2012

In this paper, an efficient means to estimate the dispersion characteristics of active FSS (or ESS) is presented. We numerically investigate the effective permittivity and the transmission coefficient of 2D metal-fiber composites using linear-lumped impedance loading. We modify the GEC method which is applied to 2D fiber composite material with arbitrary fiber orientation. We show that by varying the impedance value it is possible to control the resonance frequency of the array as well as the bandwidth.