• Journal of Environmental Health Sciences
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• v.42 no.6
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• pp.450-464
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• 2016

Objectives: This study developed and validated reference materials (RMs) to analyze metal compounds in blood. Methods: We referred to KoNEHS (Korea National Environmental Health Survey) to estimate concentrations of blood metals (cadmium, Cd; lead, Pb; mercury, Hg) and applied analytical methods (inductively coupled plasma - mass spectroscopy, ICP-MS, for Cd and Pb; graphite furnace - atomic absorption spectrometry, GF-AAS, for Cd and Pb; and direct mercury analyzer, DMA, for Hg). Homogeneity and stability tests were carried out. In addition, certified values and uncertainties of RMs were calculated through internal and external experiments. All RMs were developed and assessed in various forms according to element, analytical method, and two types of concentration levels high concentration for occupational exposure and low concentration for environmental exposure. Results: All samples showed acceptable homogeneity, except for low concentration of Cd in the GF-AAS method. Short- and long-term stabilities were satisfied by ANOVA testing. In the inter-laboratory comparison, robust medians were lower than the certified values of all RMs (robust median/reference value; $1.301/1.327{\mu}g/L$ for Cd, ICP-MS, low concentration; $3.152/3.388{\mu}g/L$ for Cd, ICP-MS, high concentration; $1.219/1.301{\mu}g/L$ for Cd, GF-AAS, low concentration; $3.074/3.321{\mu}g/L$ for Cd, GF-AAS, high concentration; $14.473/14.516{\mu}g/L$ for Pb, ICP-MS, low concentration; $50.069/50.114{\mu}g/L$ for Pb, ICP-MS, high concentration; $12.881/14.147{\mu}g/L$ for Pb, GF-AAS, low concentration; $47.015/47.591{\mu}g/L$ for Pb, GF-AAS, high concentration; $4.059/4.218{\mu}g/L$ for Hg, DMA, low concentration; $11.474/11.181{\mu}g/L$ for Hg, DMA, high concentration). Conclusion: This study demonstrates procedures for developing and validating RMs for biomonitoring in the field of the environmental health.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.11
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• pp.1305-1310
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• 2012

The performance of a system can be affected by the variance of noise factors, which arise owing to uncertainties of the material properties and environmental factors acting on the system. For robust design optimization of the system performance, it is necessary to minimize the effect of the variance of the noise factors that are impossible to control. However, present robust design techniques consider the variation of design factors, and not the noise factors, as being important. Furthermore, it is necessary to assume a normal distribution; however, a normal distribution is often not suitable to estimate the variations. In this study, a robust design technique is proposed to consider the variation of noise factors that are estimated as non-normal distributions in a real experiment. As an example of an engineering problem, a deep-sea manganese nodule miner tracked vehicle is used to demonstrate the feasibility of the proposed method.

• Analytical Science and Technology
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• v.26 no.2
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• pp.125-134
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• 2013

This study was demonstrated to estimate the measurement uncertainty of 23 multiple-component amino acids from beef bone extract by high performance liquid chromatography (HPLC). The sources of measurement uncertainty (i.e. sample weight, final volume, standard weight, purity, standard solution, calibration curve, recovery and repeatability) in associated with the analysis of amino acids were evaluated. The estimation of uncertainty obtained on the GUM (Guide to the expression of uncertainty in measurement) and EURACHEM document with mathematical calculation and statistical analysis. The content of total amino acids from beef bone extract was 36.18 g/100 g and the expanded uncertainty by multiplying coverage factor (k, 2.05~2.36) was 3.81 g/100 g at a 95% confidence level. The major contributors to the measurement uncertainty were identified in the order of recovery and repeatability (25.2%), sample pretreatment (24.5%), calibration-curve (24.0%) and weight of the reference material (10.4%). Therefore, more careful experiments are required in these steps to reduce uncertainties of amino acids analysis with a better personal proficiency improvement.

• Journal of the Earthquake Engineering Society of Korea
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• v.9 no.3 s.43
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• pp.1-8
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• 2005

This paper describes a new objective methodology of seismic building damage assessment which is called Advanced Component Method(ACM). ACM is a major attempt to replace the conventional loss estimation procedure, which is based on subjective measures and the opinions of experts, with one that objectively measures both earthquake intensity and the response ol buildings. First, response of typical buildings is obtained analytically by nonlinear seismic static analysis, push-over analyses. The spectral displacement Is used as a measure of earthquake intensity in order to use Capacity Spectrum Method and the damage functions for each building component, both structural and non-structural, are developed as a function of component deformation. Examples of components Include columns, beams, floors, partitions, glazing, etc. A repair/replacement cost model is developed that maps the physical damage to monetary damage for each component. Finally, building response, component damage functions, and cost model were combined probabilistically, using Wonte Carlo simulation techniques, to develop the final damage functions for each building type. Uncertainties in building response resulting from variability in material properties and load assumptions were incorporated in the Latin Hypercube sampling technique. The paper also presents and compares ACM and conventional building loss estimation based on historical damage data and reported loss data.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.4
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• pp.567-576
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• 2017

In a performance-based design, the structural safety is estimated from pre- defined damage states and corresponding damage indices. Both damage states and damage indices are well defined for above-ground structures, but very limited studies have been performed on underground structures. In this study, we define the damage states and damage indices of a cut-and-cover box tunnel which is one of typical structures used in metro systems, under a seismic excitation from a series of inelastic frame analyses. Three damage states are defined in terms of the number of plastic hinges that develop within the structure. The damage index is defined as the ratio of the elastic moment to the yield moment. Through use of the proposed index, the inelastic behavior and failure mechanism of box tunnels can be simulated and predicted through elastic analysis. In addition, the damage indices are linked to free-field shear strains. Because the free-field shear strain can be easily calculated from a 1D site response analysis, the proposed method can be readily used in practice. Further studies are needed to determine the range of shear strains and associated uncertainties for various types of tunnels and site profiles. However, the inter-linked platform of damage state - damage index - shear wave velocity - shear strain provides a novel approach for estimating the inelastic response of tunnels, and can be widely used in practice for seismic designs.

• Journal of Korean Tunnelling and Underground Space Association
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• v.22 no.5
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• pp.543-561
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• 2020

This paper is the result of the study on the effect of the support structure of the tunnel steel rib. In tunnel excavation, the top and bottom half excavation methods result in subsidence of steel rib reinforcement due to insufficient support of steel rib reinforcement when the ground is poor after excavation. The foundation of the steel rib installed in the upper half excavates the bottom part of the base, causing the subsidence to occur due to various effects such as internal load and lateral pressure. As a result, the tunnel is difficult to maintain and its safety is problematic. To solve these problems, steel rib support structures have been developed. For the purpose of verification, the behavior of the supporting structure is verified by model experiments reduced to shotcrete and steel rib material similarity, the numerical analysis of ΔP and ΔP generated by bottom excavation by Terzaghi theoretical equation. As a result, it was found that the support structure of 20.100~198.423 kN is required for the 10~40 m section of the depth for each soil of weathered soil~soft rock. In addition, as a result of the reduced model experiment, a fixed level of 50% steel rib deposit of steel rib support structure was installed. The study shows that the installation of steel rib support structures will compensate for uncertainties and various problems during construction. It is also thought that the installation of steel rib support structure will have many effects such as stability, economy, and air reduction.

• Analytical Science and Technology
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• v.23 no.3
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• pp.284-294
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• 2010

In this study, river water-based reference materials (RMs), NIER-I08RW and NIER-I09, for trace metal analysis were prepared and certified for Pb, Cd, Cr and Cu with evaluation of uncertainties. The RMs were confirmed to be homogeneous enough to be used as proficiency testing materials since within-bottle homogenieties of the RMs were lower than 0.3 times of targeted standard deviation of proficiency testing. The RMs were distributed to environmental testing laboratories for the proficiency testing and the variation of Z scores of the proficiency testing results were compared for different assigned values. The relative bias, $B_{relative}$, deviations between reference values and consensus values, were lower than ${\pm}$1 except for cadmium of NIERI08RW. The results showed both values were in a good agreement and only 2.9% of Z scores changed by using a different assigned values such as consensus and reference values.

• Journal of the Korean Society of Radiology
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• v.14 no.1
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• pp.7-14
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• 2020

The purpose of this study is to assess the usefulness of IR to compensate for uncertainties in inserting high density artificial objects in radiation treatment planning in the 3D-CRT treatment technique. CT images of the subjects with phantom and titanium inserted were obtained from images without IR and images with IR, and the dose evaluation factors HI, MU and volume evaluation factors Volume and PCI were compared. The results of the stainless steel and titanium phantom experiments showed that the volume of high density artificial material was reduced by 4.850% and 11.456% respectively when applying IR. MU decreased 0.924% and 1.181%. HI was down 0.106% and 0.272%. PCI decreased 0.358% and 0.867%. When IR was applied to CT images of subjects with vertebroplasty, Femur alignment pin and wrist alignment pin, the volume of artifacts decreased by 47.76%, 23.841%, and 49.339%. MU also decreased 0.924%, 0.294% and 1.675%, while HI decreased 1.232%, 0.412% and 1.695%. PCI decreases 4.022%, 0.512%, and 13.472%. In conclusion, When IR was applied to 3D-CRT treatment plan, both dose and volume in phantom and subject case with high density artificial insert were reduced.

• Korean Journal of Food Science and Technology
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• v.35 no.6
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• pp.1053-1059
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• 2003

This study aimed to determine the amount of vitamin C from vegetable & fruit juice by high performance liquid chromatograhy (HPLC). Components for estimation of measurement uncertainty associated with the analysis of vitamin C, such as standard weight, purity, molecular weight, dilution of standard solution, calibration curve, recovery, and precision, were importantly applied. The estimation of uncertainty obtained with systematic and random error based on the GUM (Guide to the expression of uncertainty in measurement) and EURACHEM document with mathematical calculation and statistical analysis. The components, evaluated ty either Type A or Type B methods, were combined to produce an overall value of uncertainty known as the combined standard uncertainty. An expanded uncertainty was obtained by multiplying the combined standard uncertainty with a coverage factor (k) calculated from the effective degree of freedom. The content of vitamin C from vegetable and fruit juice was 27.53 mg/100g and the expanded uncertainty by multiplying by the coverage factor (k, 2.06) was 0.63 mg/100g at a 95% confidence level. It was concluded that the main sources were, in order of recovery and precision, weight and purity of the reference material, dilution of the standard solution, and calibration curve. Careful experiments on other higher uncertainties is further needed in addition to better personal proficiency in sample analysis in terms of accuracy and precision.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.19 no.4 s.74
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• pp.389-398
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• 2006

Structural optimization design has been developed with finite element analysis using effective and fast computational technology. Especially topology optimization design has been recently often used since it yields an optimal topology as well as an optimal shape under satisfied constraints. In general in finite element analysis, it is assumed that the structural material properties such as Young's modulus and Poisson's ratio and the variable of applied loading are fixed with obvious values in structure. However practically these values may take uncertainties because of environmental effect or manufactural error of structures. Therefore static or dynamic analysis of the structures may make an error, then finally it may have an influence on qualify of optimal design. In this study, the topology optimization design of structure is carried out using so called the interval finite element method, and the analysis method Is proposed. The results are also validated by comparing with conventional topology optimization results of density distribution method and finite element analysis results. The present method can be used to predict the optimal topology of linear elastostatic structures with respect to structural uncertainty of behavior.