• Title/Summary/Keyword: Material Evaluations

Search Result 246, Processing Time 0.025 seconds

Radioimmunoassay Reagent Survey and Evaluation (검사별 radioimmunoassay시약 조사 및 비교실험)

  • Kim, Ji-Na;An, Jae-seok;Jeon, Young-woo;Yoon, Sang-hyuk;Kim, Yoon-cheol
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.25 no.1
    • /
    • pp.34-40
    • /
    • 2021
  • Purpose If a new test is introduced or reagents are changed in the laboratory of a medical institution, the characteristics of the test should be analyzed according to the procedure and the assessment of reagents should be made. However, several necessary conditions must be met to perform all required comparative evaluations, first enough samples should be prepared for each test, and secondly, various reagents applicable to the comparative evaluations must be supplied. Even if enough comparative evaluations have been done, there is a limit to the fact that the data variation for the new reagent represents the overall patient data variation, The fact puts a burden on the laboratory to the change the reagent. Due to these various difficulties, reagent changes in the laboratory are limited. In order to introduce a competitive bid, the institute conducted a full investigation of Radioimmunoassay(RIA) reagents for each test and established the range of reagents available in the laboratory through comparative evaluations. We wanted to share this process. Materials and Methods There are 20 items of tests conducted in our laboratory except for consignment tests. For each test, RIA reagents that can be used were fully investigated with the reference to external quality control report. and the manuals for each reagent were obtained. Each reagent was checked for the manual to check the test method, Incubation time, sample volume needed for the test. After that, the primary selection was made according to whether it was available in this laboratory. The primary selected reagents were supplied with 2kits based on 100tests, and the data correlation test, sensitivity measurement, recovery rate measurement, and dilution test were conducted. The secondary selection was performed according to the results of the comparative evaluation. The reagents that passed the primary and secondary selections were submitted to the competitive bidding list. In the case of reagent is designated as a singular, we submitted a explanatory statement with the data obtained during the primary and secondary selection processes. Results Excluded from the primary selection was the case where TAT was expected to be delayed at the moment, and it was impossible to apply to our equipment due to the large volume of reagents used during the test. In the primary selection, there were five items which only one reagent was available.(squamous cell carcinoma Ag(SCC Ag), β-human chorionic gonadotropin(β-HCG), vitamin B12, folate, free testosterone), two reagents were available(CA19-9, CA125, CA72-4, ferritin, thyroglobulin antibody(TG Ab), microsomal antibody(Mic Ab), thyroid stimulating hormone-receptor-antibody(TSH-R-Ab), calcitonin), three reagents were available (triiodothyronine(T3), Tree T3, Free T4, TSH, intact parathyroid hormone(intact PTH)) and four reagents were available are carcinoembryonic antigen(CEA), TG. In the secondary selection, there were eight items which only one reagent was available.(ferritin, TG, CA19-9, SCC, β-HCG, vitaminB12, folate, free testosterone), two reagents were available(TG Ab, Mic Ab, TSH-R-Ab, CA125, CA72-4, intact PTH, calcitonin), three reagents were available(T3, Tree T3, Free T4, TSH, CEA). Reasons excluded from the secondary selection were the lack of reagent supply for comparative evaluations, the problems with data reproducibility, and the inability to accept data variations. The most problematic part of comparative evaluations was sample collection. It didn't matter if the number of samples requested was large and the capacity needed for the test was small. It was difficult to collect various concentration samples in the case of a small number of tests(100 cases per month or less), and it was difficult to conduct a recovery rate test in the case of a relatively large volume of samples required for a single test(more than 100 uL). In addition, the lack of dilution solution or standard zero material for sensitivity measurement or dilution tests was one of the problems. Conclusion Comparative evaluation for changing test reagents require appropriate preparation time to collect diverse and sufficient samples. In addition, setting the total sample volume and reagent volume range required for comparative evaluations, depending on the sample volume and reagent volume required for one test, will reduce the burden of sample collection and planning for each comparative evaluation.

Quality evaluations of bell pepper in cold system combined with TEM (thermoelectric materials) and PCM (phase change material) (PCM을 장착한 열전소자 냉각시스템의 저장 중 피망의 품질 평가)

  • Sung, Jung-Min;Kim, So-Hee;Kim, Byeong-Sam;Kim, Jong-Hoon;Kim, Ji-Young;Kwon, Ki-Hyun
    • Food Science and Preservation
    • /
    • v.23 no.4
    • /
    • pp.471-478
    • /
    • 2016
  • For the distribution of fresh produce, the thermoelectric cooling system combined with thermo electric materials (TEM) and phase change material (PCM) was studied. The PCM used this study was produced by in-situ polymerization technology which referred microencapsulation of hydrocarbon (n-tetradecane and n-hexadecane). In this study, quality characteristics of bell peppers in thermoelectric cooling system combined with TEM and PCM were analyzed and control was placed in an EPS (expanded polystyrene) box. As a result of quality characteristics analysis, weight of bell peppers decreased and moisture content of bell peppers was 90.96~94.43% during storage. Vitamin C content of bell pepper decreased during storage and reduction ratio of control was higher than that of BPT-5 treatment(bell pepper in thermoelectric cooling system with PCM which is kept the temperature at $5^{\circ}C$). The result of color value, on 21 day, ${\Delta}E$ value of BPT-5 treatment was 5.05 while that of control was 41.8. On 21 day, total bacteria count of BPT-5 treated bell pepper shown less than that of control. In conclusion, it suggested that the thermoelectric cooling system combined with PCM improved quality of fresh produce during transportation and storage.

The Effect of $\beta$-Tricalcium Phosphate and Deproteinized Bovine Bone on Bone Formation in the Defects of Rat Calvaria (흰쥐 두개골 결손부에서 베타-트리칼슘 인산염과 탈단백우골의 골형성 효과)

  • Jung, Seung-Gon;Park, Hong-Ju;Ryu, Sun-Youl
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.32 no.4
    • /
    • pp.313-323
    • /
    • 2010
  • Purpose: This study was conducted to evaluate the effect of beta-tricalcium phosphate (Cerasorb$^{(R)}$, Germany) and deproteinized bovine bone (Bio-Oss$^{(R)}$, Switzerland) grafted to the defect of rat calvaria artificially created and the effect of use of absorbable membrane (BioMesh$^{(R)}$, Korea) on new bone formation. Materials and Methods: Transosseous circular calvarial defects with diameters of 5 mm were prepared in the both parietal bone of 30 rats. In the control group I, no specific treatment was done on the defects. In the control group II, the defects were covered with absorbable membrane. In the experimental group I, deproteinized bovine bone was grafted without absorbable membrane; in the experimental group II, deproteinized bovine bone was grafted with absorbable membrane; in the experimental group III, beta-tricalcium phosphate was grafted without absorbable membrane; in the experimental group IV, beta-tricalcium phosphate was grafted with absorbable membrane. The animals were sacrificed after 3 weeks and 6 weeks respectively, and histologic and histomorphometric evaluations were performed. Results: Compare to the control groups, the experimental groups showed more newly formed bone. Between the experimental groups, beta-tricalcium phosphate showed more resorption than deproteinized bovine bone. Stabilization of grafted material and interception of the soft tissue invasion was observed in the specimen treated with membrane. There was no statistical difference between the experimental group I, III and experimental group II, IV classified by graft material, but statistically significant increase in the amount of newly formed bone was observed in the experimental group I, II and II, IV classified by the use of membrane (P<0.05). Conclusion: Both beta-tricalcium phosphate and deproteinized bovine bone showed similar osteoconductibility, but beta-tricalcium phosphate is thought to be closer to ideal synthetic graft material because it showed higher resorption rate in vivo. Increased new bone formation can be expected in bone graft with use of membrane.

Structural Performance Evaluation of Anchors for Power Equipment Electrical Cabinets Considering On-Site Installation Conditions (현장 설치 조건을 고려한 발전설비 전기 캐비닛 정착부 앵커의 구조성능 평가)

  • Lee, Sang-Moon;Jung, Woo-Young
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.43 no.6
    • /
    • pp.709-719
    • /
    • 2023
  • In general, most of the electrical equipment responsible for control within power plants is housed in self-standing cabinets. These cabinets are typically fixed to a slab using post-installed anchors. Although the fixation method of using post-installed anchors provides stability, there is a risk of conductor failure due to external forces, including moments. However, the performance assessment of current anchors is only evaluated through uniaxial material tests. Therefore, the primary purpose of this study is to compare the static performance of post-installed anchors, considering on-site installation conditions, with their performance in material tests and to analyze the behavioral characteristics of the anchors. While conducting experiments using actual cabinets would be ideal, practical and spatial constraints make this approach difficult. As an alternative, experiments were conducted using a test specimen consisting of a steel column and a support. As a result, the pull-out performance of anchors reflecting on-site installation conditions was measured to be about 10% higher than that observed in material tests. The trends in load reduction and the point of maximum performance for the anchors also differed. To verify the reliability of the experimental study, a 3D FEM analysis was performed, which will provide predictive information on the loads transferred to the post-installed anchors for structural performance evaluations of electrical cabinets using shaking table test in the future.

A Study on Wearable Augmented Reality-Based Experiential Content: Focusing on AR Stone Tower Content (착용형 증강현실 기반 체험형 콘텐츠 연구: AR 돌탑 콘텐츠를 중심으로)

  • Inyoung Choi;Hieyong Jeong;Choonsung Shin
    • Smart Media Journal
    • /
    • v.13 no.4
    • /
    • pp.114-123
    • /
    • 2024
  • This paper proposes AR stone tower content, an experiential content based on wearable augmented reality (AR). Although wearable augmented reality is gaining attention, the acceptance of the technology is still focused on specialized applications such as industrial sites. On the other hand, the proposed AR stone tower content is based on the material of 'stone tower' so that general users can relate to it and easily participate in it, and it is organized to utilize space in a moving environment and find and stack stones based on natural hand gestures. The proposed AR stone tower content was implemented in the HoloLens 2 environment and evaluated by general users through a pilot exhibition in a small art museum. The evaluation results showed that the overall satisfaction with the content averaged 3.85, and the content appropriateness for the stone tower material was very high at 4.15. In particular, users were highly satisfied with content comprehension and sound, but somewhat less satisfied with object recognition, body adaptation, and object control. The above user evaluations confirm the resonance and positive response to the material, but also highlight the difficulties of the average user in experiencing and interacting with the wearable AR environment.

Statistical Variability of Mechanical Properties of Reinforcements (철근 콘크리트용 봉강의 역학적 특성의 통계적 변동성)

  • Kim, Jee Sang;Paek, Min Hee
    • KSCE Journal of Civil and Environmental Engineering Research
    • /
    • v.31 no.2A
    • /
    • pp.115-120
    • /
    • 2011
  • The strength of reinforced concrete members has uncertainty from material properties of, concrete and reinforcements, section dimensions, and construction errors and so on. The accurate evaluation of these uncertainties is necessary to assure the reasonable safety. The uncertainties should be taken into account in design using structural reliability theory which requires probabilistic models for such uncertainties. In current Korean design code, most reliability evaluations were performed based on foreign data because of lack of local data. In this paper, the probabilistic models for yield strength of reinforcements were developed based on local data. The effects of various factors, nominal yield strength, diameter of reinforcements, and companies, on the models are also examined. According to data analysed, the effects of those factors are not significant. The probability model for yield strength of reinforcements in Korea can be expressed with Beta distribution based on collected data.

Evaluation of Conservation Conditions of Nara National Archives Documents (나라기록관 종이기록물의 보존 상태 평가)

  • Lee, Sang Kyu;Shin, Kwang Hyun;Kim, Hojin;Shin, Hyun Chang
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.46 no.2
    • /
    • pp.22-29
    • /
    • 2014
  • Many government agencies have used domestic deacidification equipments to stabilize archives; however, no agency has verified archives' current preservative status. We studied the Nara National Archives' documents that had treated by mass deacidification process from 2001 to 2012, in order to examine the documents' preservative status and how efficient the mass deacidification has been. Approximately 1% of total 112,970 Nara National Archives' documents treated by mass deacidification were randomly selected and evaluated on their current measure of acidity and color change. Regardless of the kinds of document material, a wide range of pH level was found. Especially those documents that were treated by mass deacidification equipment after 2006 showed acidic conditions that were less than pH 6.8 level. Those documents were probably not treated properly by deacidifying chemical because of tightly packing style. The current measures of acidity and color records will be useful as a reference for future evaluations of further decay of the documents. It was the first study to evaluate acidity and color conditions of Nara National Archives' documents treated by mass deacidification equipment. We concluded that when using mass deacidification equipment, archives should not be loaded tightly in order for them to be fully in contact with deacidifying chemical.

Evaluations of Magnetic Abrasive Polishing and Distribution of Magnetic Flux Density on the Curvature of Non-Ferrous Material (곡면 자기연마에서의 자기력 형성과 가공특성에 관한 연구)

  • Kim, Sang-Oh;Kwak, Jae-Seob
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.36 no.3
    • /
    • pp.259-264
    • /
    • 2012
  • Automatic magnetic abrasive polishing (MAP), which can be applied after machining of a mold on a machine tool without unloading, is very effective for finishing a free-form surface such as a complicated injection mold. This study aimed to improve the efficiency of MAP of a non-ferrous mold surface. The magnetic array table and control of the electromagnet polarity were applied in the MAP of a free-form surface. In this study, first, the magnetic flux density on the mold surface was simulated to determine the optimal conditions for the polarity array. Then, the MAP efficiency for polishing a non-ferrous mold surface was estimated in terms of the change in the radius of curvature and the magnetic flux density. The most improved surface roughness was observed not only in the upward tool path but also in the working area of larger magnetic flux density.

A Study on the Material Characteristics of Contacts on Bias Track Relay (바이어스 궤도계전기 접점의 재질 특성에 관한 연구)

  • Kim, Hee-Dae;Lee, Sung-Il
    • Journal of the Korean Society for Railway
    • /
    • v.15 no.6
    • /
    • pp.597-603
    • /
    • 2012
  • The cases for selecting contact materials of Ag and AgC for Bias Track Relay are the studies and their safety evaluations are proposed in this paper. The welding at the relative low current has occurred in Ag contacts, but the one has not occurred in AgC contacts although the high currents flow since it has an excellent temperature characteristic. In the repetitive switching experiment, more unstable resistance and transfer phenomena has occurred in contacts as the switching numbers of AgC contacts increase, which results in more consumption of contacts. In the experiments, there exists a trade off relationship between welding and resistance variation. AgC contacts have excellent characteristics in welding, but the caution is required in using them since a lot of repetition switching produces much resistance variation. However, Ag contacts have excellent characteristics in repetitive switching, but weak ones in welding.

Engineering properties of expansive soil treated with polypropylene fibers

  • Ali, Muhammad;Aziz, Mubashir;Hamza, Muhammad;Madni, Muhammad Faizan
    • Geomechanics and Engineering
    • /
    • v.22 no.3
    • /
    • pp.227-236
    • /
    • 2020
  • Expansive soils are renowned for their swelling-shrinkage property and these volumetric changes resultantly cause huge damage to civil infrastructures. Likewise, subgrades consisting of expansive soils instigate serviceability failures in pavements across various regions of Pakistan and worldwide. This study presents the use of polypropylene fibers to improve the engineering properties of a local swelling soil. The moisture-density relationship, unconfined compressive strength (UCS) and elastic modulus (E50), California bearing ratio (CBR) and one-dimensional consolidation behavior of the soil treated with 0, 0.2, 0.4, 0.6 and 0.8% fibers have been investigated in this study. It is found that the maximum dry density of reinforced soil slightly decreased by 2.8% due to replacement of heavier soil particles by light-weight fibers and the optimum moisture content remained almost unaffected due to non-absorbent nature of the fibers. A significant improvement has been observed in UCS (an increase of 279%), E50 (an increase of 113.6%) and CBR value (an increase of 94.4% under unsoaked and an increase of 55.6% under soaked conditions) of the soil reinforced with 0.4% fibers, thereby providing a better quality subgrade for the construction of pavements on such soils. Free swell and swell pressure of the soil also significantly reduced (94.4% and 87.9%, respectively) with the addition of 0.8% fibers and eventually converting the medium swelling soil to a low swelling class. Similarly, the compression and rebound indices also reduced by 69.9% and 88%, respectively with fiber inclusion of 0.8%. From the experimental evaluations, it emerges that polypropylene fiber has great potential as a low cost and sustainable stabilizing material for widespread swelling soils.