• BMB Reports
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• v.34 no.4
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• pp.305-309
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• 2001

MatR in Rhizobium trifolii is a malonate-responsive transcription factor that regulates the expression of genes, matABC, enabling decarboxylation of malonyl-CoA into acetyl-CoA, synthesis of malonyl-CoA from malonate and CoA, and malonate transport. According to an analysis of the amino acid sequence homology, MatR belongs to the GntR family The proteins of this family have two-domain folds, the N-terminal helix-turn-helix DNA-binding domain and the C-terminal ligand-binding domain. In order to End the malonate binding site and amino acid residues that interact with RNA polymerase, a site-directed mutagenesis was performed. Analysis of the mutant MatR suggests that Arg-160 might be involved in malonate binding, whereas Arg-102 and Arg-174 are critical for the repression activity by interacting with RNA polymerase.

• 한국신재생에너지학회:학술대회논문집
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• 2008.10a
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• pp.102-102
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• 2008

• 한국신재생에너지학회:학술대회논문집
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• 2008.10a
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• pp.103-103
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• 2008

• Proceedings of the Materials Research Society of Korea Conference
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• 1998.08a
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• pp.42.2-42
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• 1998

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.28 no.6
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• pp.400-402
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• 2015

The typical winter heating unit heating mat. The product is to be found in the development of new water heating mat today. The product that circulates the water through the hose inside the mat with your existing heating mat electric heated mat is different from boiling water. However, no clear standards for noise and safety, consumer choice is giving confusing information about the product is low. We were to develop a high heat retention and stability than conventional sleeping mats to produce creative than traditional hot mats, heated mats general comparison with experimental results is a more efficient heat retention mat is produced.

• 한국신재생에너지학회:학술대회논문집
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• 2008.05a
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• pp.397-397
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• 2008

• Proceedings of the Materials Research Society of Korea Conference
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• 1997.05a
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• pp.56-56
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• 1997

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6433-6438
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• 2013

In hepatocellular cancer (HCC), lack of response to chemotherapy and radiation treatment can be caused by a loss of epigenetic modifications of cancer cells. Methionine adenosyltransferase 1A is inactivated in HCC and may be stimulated by an epigenetic change involving promoter hypermethylation. Therefore, drugs releasing epigenetic repression have been proposed to reverse this process. We studied the effect of the demethylating reagent 5-aza-2'-deoxycitidine (5-Aza-CdR) on MAT1A gene expression, DNA methylation and S-adenosylmethionine (SAMe) production in the HCC cell line Huh7. We found that MAT1A mRNA and protein expression were activated in Huh7 cells with the treatment of 5-Aza-CdR; the status of promoter hypermethylation was reversed. At the same time, MAT2A mRNA and protein expression was significantly reduced in Huh7 cells treated with 5-Aza-CdR, while SAMe production was significantly induced. However, 5-Aza-CdR showed no effects on MAT2A methylation. Furthermore, 5-Aza-CdR inhibited the growth of Huh7 cells and induced apoptosis and through down-regulation of Bcl-2, up-regulation of Bax and caspase-3. Our observations suggest that 5-Aza-CdR exerts its anti-tumor effects in Huh7 cells through an epigenetic change involving increased expression of the methionine adenosyltransferase 1A gene and induction of S-adenosylmethionine production.

• Composites Research
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• v.37 no.3
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• pp.143-149
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• 2024

This paper measures the mechanical properties of corrugated cardboard, an eco-friendly packaging material, and applies these measurements to the MAT_PAPER model in LS-DYNA for finite element analysis. Although MAT_PAPER is primarily designed for modeling the behavior of paper, this research demonstrates its applicability to corrugated cardboard as well. Tensile, compression, and shear behaviors of a corrugated cardboard were measured and analyzed, and based on these results, six yield surfaces were derived and integrated into the MAT_PAPER model. By comparing the finite element analysis of the material tests and the low velocity collapse analysis of the corrugated cardboard square boxes with each experimental results, it was shown that the behavior of corrugated cardboard could be equivalently considered well by the MAT_PAPER model. However, since the model is not rate-dependent, the high strain rate properties of liner materials were measured and used for strain rate correction. Consequently, this matches well with the results of the high-speed compression tests of the corrugated cardboard square boxes.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.1
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• pp.99-108
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• 2012

Soil erosion and sediment from agricultural farmland has caused various negative impacts on environment in recent years. The effect of rice straw mat on soil erosion has been investigated by many researchers these days. In this study, the SWAT model was applied to Hongcheon watershed to evaluate SWAT flow and sediment, and the effect of rice straw mat on sediment yield at watershed outlet was evaluated. The Nash-Sutcliffe model efficiency (NSE) and coefficient of determination ($R^2$) values for flow simulation (calibration period) were 0.66 and 0.67, and the NSE values for sediment was 0.90. The calibrated parameters were used to analyze the reduction of sediment yield in the farmland with rice straw mat. Average daily sediment yield without rice straw mat was 49.8 ton/day and sediment yield with rice straw mat was 25.5 ton/day, and the reduction rate was 38.7 %. Also, average daily sediment yield with/without rice straw mat were 97.5 ton/day and 190.7 ton/day during the rainy season (Jun. 2008 - Aug. 2009), with the reduction rate 46.3 %.