• Geomechanics and Engineering
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• v.23 no.6
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• pp.587-600
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• 2020

Shear-induced instability of jointed rock mass has greatly threatened the safety of underground openings. To better understand the failure mechanism of surrounding rock mass under shear, the flawed specimens containing a circular opening and two open joints are prepared and used to conduct direct shear tests. Both experimental and numerical results show that joint inclination (β) has a significant effect on the shear strength, dilation, cracking behavior and stress distribution around flaws. The maximum shear strength, occurring at β=30°, usually corresponds to a unifrom stress state around joint and an intense energy release. However, a larger joint inclination, such as β=90°~150°, will cause a more uneven stress distribution and a stronger stress concentration, thus a lower shear strength. The stress distribution around opening changes little with joint inclination, while the magnitude varys much. Both compression and tension around opening will be greatly enhanced by the 30°-joints. In addition, a higher normal stress tends to enhance the compression and suppress the tension around flaws, resulting in an earlier generation and a larger proportion of shear cracks.

• Clean Technology
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• v.28 no.1
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• pp.32-37
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• 2022

Food waste is produced from food factories, food services, and home kitchens. The generated mass reached 5.4 million tons/year in 2020. The basic management technology for such waste has been biological degradation under an anaerobic environment. However, the whole process is intrinsically slow and considerably affected by the inner physicochemical properties of the waste and other surrounding conditions, which makes optimization of the process difficult. The most promising options to counter this massive generation of waste are eco-friendly treatments or recycling. As a preliminary step for these options, attempts were made to evaluate the feasibility and usability of three simulative models based on reaction kinetics. Model (A) predicted relative changes over reaction time for reactant, intermediate, and product. Overall, an increased reaction rate produced less intermediate and more product, thereby leading to a shorter total reaction time. Particle diminishing model (B) predicted reduction of the total waste mass. The smaller particles diminished faster along with the dominant effect of microbial reaction. In Model (C), long-chain cellulose was predicted to transform into reducing sugar. At a standard condition, 48% of cellulose molecules having 10⁵ repeating units turned into reducing sugar after 100 h. Also it was found that the optimal enzyme concentration where the highest amount of remnant sugar was harvested was 1 mg L^-1.

• Korean Journal of Exercise Nutrition
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• v.24 no.1
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• pp.1-8
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• 2020

[Purpose] This study compared differences in trabecular bone architecture and strength caused by jump and running exercises in rats. [Methods] Ten-week-old male Wistar rats (n=45) were randomly assigned to three body weight-matched groups: a sedentary control group (CON, n=15); a treadmill running group (RUN, n=15); and a jump exercise group (JUM, n=15). Treadmill running was performed at 25 m/min without inclination, 1 h/day, 5 days/week for 8 weeks. The jump exercise protocol comprised 10 jumps/day, 5 days/week for 8 weeks, with a jump height of 40 cm. We used microcomputed tomography to assess microarchitecture, mineralization density, and fracture load as predicted by finite element analysis (FEA) at the distal femoral metaphysis. [Results] Both jump and running exercises produced significantly higher trabecular bone mass, thickness, number, and fracture load compared to the sedentary control group. The jump and running exercises, however, showed different results in terms of the structural characteristics of trabecular bone. Jump exercises enhanced trabecular bone mass by thickening the trabeculae, while running exercises did so by increasing the trabecular number. FEA-estimated fracture load did not differ significantly between the exercise groups. [Conclusion] This study elucidated the differential effects of jump and running exercise on trabecular bone architecture in rats. The different structural changes in the trabecular bone, however, had no significant impact on trabecular bone strength.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.04a
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• pp.71-71
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• 1995

The succinic semialdehyde dehydrogenase which is one of the key enzyme of GABA shunt in CNS has been purified from bovine brain homogeneously for the first time. The molecular mass of the native enzyme was estimated to be approximately 110,000 on gel filtration, The subunit molecular mass was determined by SDS-PAGE to be 54,000. These results indicate that the enzyme is a dimeric protein made up to identical subunits. Chemical modification studies of the enzyme suggest that the critical lysyl, connected with catalytic activity of the enzyme, The binding of IAF-SSDH(enzyme tagged with fluoreceine) to GABA transaminase which catalyzes the degradation of GABA was monitored by steady emission anisotropy. The changes of fluorescence anisotropy by interactions between two enzymes suggest that the formation of enzyme cluster must be invoved in the regulation of GABA concentration in brain tissues. The inhibitory effects of some antiepileptic and anticonvulsant drugs on the enzyme were also examined.

• Korean Journal of Radiology
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• v.24 no.1
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• pp.62-78
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• 2023

As the majority of incidentally detected lesions in the anterior mediastinum is small nodules with soft tissue appearance, the differential diagnosis has typically included thymic neoplasm and prevascular lymph node, with benign cyst. Overestimation or misinterpretation of these lesions can lead to unnecessary surgery for ultimately benign conditions. Diagnosing mediastinal cysts using MRI serves as a problem-solving modality in distinguishing between surgical and nonsurgical anterior mediastinal lesions. The pitfalls of MRI evaluation for anterior mediastinal cystic lesions are as follows: first, we acknowledge the limitation of T2-weighted images for evaluating benign cystic lesions. Due to variable contents within benign cystic lesions, such as hemorrhage, T2 signal intensity may be variable. Second, owing to extensive necrosis and cystic changes, the T2 shine-through effect may be seen on diffusion-weighted images (DWI), and small solid portions might be missed on enhanced images. Therefore, both enhancement and DWI with apparent diffusion coefficient values should be considered. An algorithm will be suggested for the diagnostic evaluation of anterior mediastinal cystic lesions, and finally, a management strategy based on MRI features will be suggested.

• Journal of the Korean Society of Radiology
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• v.84 no.5
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• pp.1176-1180
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• 2023

Granular cell tumors (GCTs) are rare soft tissue tumor, originating from neural or perineural cells. We present a case of axillary GCT in a 69-year-old woman with breast cancer history and discuss the various radiologic findings. US revealed a circumscribed oval heterogeneous iso- and hyperechoic mass in the left axilla. Chest CT showed a well-defined, oval, and mildly enhancing mass in the left axilla on the lateral aspect of the pectoralis muscle. A final diagnosis of GCT was made through US-guided core needle biopsy. Follow-up US showed no significant changes in the axillary GCT. Familiarity with GCT may facilitate early diagnosis and subsequent management.

• Fashion & Textile Research Journal
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• v.26 no.3
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• pp.273-278
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• 2024

Consumer preferences for food are influenced by personal values and personalities. Social, economic, and cultural developments in modern society have influenced consumer lifestyles and brought about multiple changes in consumption patterns. In the beauty market, consumers are now more interested in specialized offerings, and an increasing number of people are opting for customized products in a market structure where mass production has led to mass consumption. Hair products are now manufactured as functional cosmetics designed to maintain and improve scalp health and hair growth by removing waste from the scalp and adding fragrance for cleanliness, breaking away from the concept of general cosmetics. Many studies have focused on personalized products in the cosmetics industry. This study aimed to accurately determine scalp types and further diagnose individual scalp conditions using a scalp diagnostic device. Based on the diagnoses, it recommended and provided personalized shampoos in order to understand how these shampoos improved scalp health. By objectively analyzing and comparing scalp conditions before and after using customized shampoos, the study demonstrated a significant effect on scalp health. The results of this study confirmed the perception and effectiveness of personalized shampoos.

• Composites Research
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• v.37 no.5
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• pp.416-421
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• 2024

Satellites operating in low Earth orbit environments (400~700 km) are constantly subjected to severe thermal cycles, ultraviolet radiation, and collisions with atomic oxygen (AO), which might cause continuous damage. Particularly, collisions with AO oxidize and erode polymer matrices, reducing surface mass and degradation of material properties. Therefore, to analyze these effects, Reax-FF molecular dynamics simulations were adopted. More than qualitative studies of mass loss due to AO interactions between materials in the previous NVE analysis, we quantified erosion rates as a function of temperature within the operational range of actual satellites (200 K~400 K) using NVT analysis. We also analyzed changes in reaction patterns occurring on the surface and effects due to polymer phase transitions.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.36 no.5
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• pp.185-191
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• 2014

Purpose: Although there have been several studies of reduced airway space after mandibular setback surgery using the sagittal split ramus osteotomy technique, research on the risk factors for changes of the airway space is lacking. Therefore, this study was performed to examine airway changes and the position of the hyoid bone after orthognathic surgery, and to assess possible risk factors. Methods: In this retrospective study, 50 patients who underwent posterior displacement of the mandible by the bilateral sagittal split ramus osteotomy technique were included. Changes of the position of the hyoid bone and the airway space were analyzed over various follow-up periods, using cephalometric radiography taken preoperatively, immediately after surgery, eight weeks after surgery, six months after surgery, and one year after surgery. To identify risk factors, multiple regression analysis of age, gender, body mass index (BMI), posterior mandibular movement, and the presence of genioplasty was performed. Results: Inferor and posterior movement of the hyoid bone was observed postoperatively, but subsequent observations showed regression towards the anterosuperior aspect. The airway space also significantly decreased after surgery (P<0.05), and increased slightly up until six months after surgery. The airway space significantly decreased (${\beta}=0.47$, P<0.01) as the amount of mandibular setback increased. However, age, sex, BMI, and presence of genioplasty were not associated with airway reduction. Conclusion: The amount of mandibular set back was significantly associated with postoperative reduction of airway space. It is necessary to establish a treatment plan considering this factor.

• Journal of Korean Tunnelling and Underground Space Association
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• v.6 no.1
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• pp.71-83
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• 2004

The purpose of this study is to present an analysis method for the prediction of the changes m ground conditions. To this end, three dimensional convergence displacements are analyzed in several ways to estimate the trend of displacement changes. Three-dimensional arching effect is occurred around the unsupported excavation surface including tunnel face when a tunnel is excavated in a stable rock mass. If the ground condition ahead of tunnel face changes or a weak zone exists, a diagnostic trend of displacement change is observed by the 3 dimensional measurement and numerical analysis. Therefore, the change of ground condition and the existence of a weak zone ahead of tunnel face can be predicted by monitoring 3-dimensional absolute displacements during excavation, and applying the methodology (the ratio of L/C, $C/C_o$, etc.) presented in this study.