• Journal of Ginseng Research
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• v.42 no.3
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• pp.270-276
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• 2018

Background: Notoginsenoside Ft1 is a promising potential candidate for cardiovascular and cancer disease therapy owing to its positive pharmacological activities. However, the yield of Ft1 is ultralow utilizing reported methods. Herein, an acid hydrolyzing strategy was implemented in the acquirement of rare notoginsenoside Ft1. Methods: Chemical profiles were identified by ultraperformance liquid chromatography coupled with quadruple-time-of-flight and electrospray ionization mass spectrometry (UPLC-Q/TOF-ESI-MS). The acid hydrolyzing dynamic changes of chemical compositions and the possible transformation pathways of saponins were monitored by ultrahigh-performance LC coupled with tandem MS (UHPLC-MS/ MS). Results and conclusion: Notoginsenoside Ft1 was epimerized from notoginsenoside ST4, which was generated through cleaving the carbohydrate side chains at C-20 of notoginsenosides Fa and Fc, and vinaginsenoside R7, and further converted to other compounds via hydroxylation at C-25 or hydrolysis of the carbohydrate side chains at C-3 under the acid conditions. High temperature contributed to the hydroxylation reaction at C-25 and 25% acetic acid concentration was conducive to the preparation of notoginsenoside Ft1. C-20 epimers of notoginsenoside Ft1 and ST4 were successfully separated utilizing solvent method of acetic acid solution. The theoretical preparation yield rate of notoginsenoside Ft1 was about 1.8%, which would be beneficial to further study on its bioactivities and clinical application.

• Korean Journal of Agricultural Science
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• v.10 no.1
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• pp.118-128
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• 1983

Simulation model of natural air grain drying was discussed and modified to predict the changes of grain moisture content and dry matter loss of rough rice drying. The modified simulation model was then validated using actual test data. A series of simulated drying tests using official weather data for 15 years from Beaumont, Texas, was taken to make minimum airflow rate and maximum bed depth of rough rice drying by natural air, under different conditions of initial moisture content of rough rice, airflow rate and harvest date.

• Food Science and Preservation
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• v.14 no.3
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• pp.308-314
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• 2007

To investigate effects of fermentation on volatile components, we analyzed volatile organic compounds of raw and fermented Rhus verniciflua S. bark. A 50%(w/v) sugar solution was used for fermentation. Volatile organic compounds of raw and fermented Rhus verniciflua S. were extracted by the simultaneous steam distillation and extraction(SDE) method, with a mixture of n-pentane and diethylether(1:1, v/v) and analyzed by gas chromatograph-mass spectrometer. A total of 51 and 27 volatile organic compounds were detected in raw and fermented samples, respectively, and were mainly alcohols. Compounds such as ethyl acetate, 2-methyl-3-buten-2-ol, 3-methylbutanal, 1-octen-3-o1, 3-methyl-2-butanone, hexanal and pentanal were detected as the primary compounds in the raw sample. The fermented sample showed sour different volatile compounds, such as ethanol, ethyl acetate, ethyl lactate and 3-methylbutanol. Thus, a number of volatile organic compounds were synthesized after fermentation of Rhus verniciflua S. bark.

• Journal of Life Science
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• v.27 no.9
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• pp.1047-1051
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• 2017

Due to aging, the physical fitness of middle-aged women decreases after menopause. This results in increased body fat and reduced lean body mass, both of which can lead to obesity. This phenomenon is accompanied by changes in hormone secretion in the body. The purpose of this study was to analyze the effects of circuit training on aging-related hormones in obese middle-aged women. The subjects were 20 obese middle-aged women. The subjects were divided into two groups: a circuit training group (n=10) and nonexercise control group (n=10). Growth hormone (GH), insulin-like growth factor-1 (IGF-1), estrogen, and DHEA-S were measured before and after the circuit training program. The circuit training group performed circuit training for 12 weeks, three times per week. Exercise intensity was increased gradually from 60% to 80% of heart rate reserve every 6 weeks. In the circuit training group, at the end of the 12-week training program, the IGF-1 levels were significantly increased compared to pre-exercise levels, and they were higher than those of the control group. GH levels were also significantly increased in the circuit training group, but the differences were not statistically significant. DHEA-S was significantly increased in the circuit training group, but the difference was not statistically significant. The results showed that circuit training improved aging-related hormones levels in obese middle-aged women.

• Korean Journal of Agricultural and Forest Meteorology
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• v.16 no.3
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• pp.188-196
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• 2014

This study aimed to understand the nutrient absorption, usage and allocation of Carpinus cordata in different soil and light environments. Seasonal changes of foliar nitrogen, phosphorous, chlorophyll contents, leaf mass per area (LMA) and nutrient retranslocation rates were investigated for C. cordata saplings growing in a natural deciduous broadleaved forest and an Manchurian fir (Abies holophylla) plantation in Gwangneung, Kyunggido. The deciduous forest had lower leaf area, higher light penetration, and better soil fertility than the Manchurian fir forest. However, available soil phosphorous content in the deciduous forest was only one third of that in the Manchurian fir forest, which caused lower foliar phosphorous content and higher P retranslocation rate of C. cordata in the deciduous forest than that in the Mancurian fir forest. Soil nitrogen contents in the deciduous forest were higher than that in the Manchurian fir forest, however, no differences in foliar nitrogen content and retranslocation rate in C. cordata between the two stands were found. C. cordata in the Manchurian fir forest with high LAI throughout a year, had lower LMA, foliar nitrogen content and chlorophyll a/b, while had higher total chlorophyll content and chlorophyll/N than that in the deciduous forest. These results implied C. cordata under different environments are using different strategies for nutrient use and allocations.

• Journal of Sensor Science and Technology
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• v.8 no.5
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• pp.368-376
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• 1999

This paper predicts the changes in the spring constant, the resonant frequency, the electrostatic force, and the displacement of a resonant structure due to non-ideal anisotropic RIE etching process. First, a $6\;{\mu}m$ thick polysilicon was etched by RIE and the anisotropy of the etched structure was measured as a function of a RF power, a $Cl_2$ flow rate and a chamber pressure. In the experimental results, an anisotropy was decreased as the RF power, the $Cl_2$ flow rate, or the chamber pressure was increased. A comb actuator's operation characteristic was predicted depending on the anisotropy variations in RIE etching. Comb actuators with three different support beam structures were investigated : fixed-fixed, crab-leg, and double crab-leg. As the RIE etch anisotropy becomes non-ideal, i.e. the cross section becomes rather a trapezoidal than a rectangular shape, it decreases spring constant, resonant frequency and electrostatic force of a comb actuator but it increases the displacement of the mass. Among the three structures, the comb actuator with double crab-leg support beams is more influenced by anisotropy variation in RIE etch than other two.

• Economic and Environmental Geology
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• v.35 no.3
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• pp.273-284
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• 2002

The Gravity-Geologic Method (GGM) was implemented for bathymetric determinations in the Drake Passage, Antarctica, using global marine Free-air Gravity Anomalies (FAGA) data sets by Sandwell and Smith (1997) and local echo sounding measurements. Of the 6548 bathymetric sounding measurements, two thirds of these points were used as control depths, while the remaining values were used as checkpoints. A density contrast of 9.0 gm/㎤ was selected based on the checkpoints predictions with changes in the density contrast assumed between the seawater and ocean bottom topographic mass. Control depths from the echo soundings were used to determine regional gravity components that were removed from FAGA to estimate the gravity effects of the bathymetry. These gravity effects were converted to bathymetry by inversion. In particular, a selective merging technique was developed to effectively combine the echo sounding depths with the GGM bathymetiy to enhance high frequency components along the shipborne sounding tracklines. For the rugged bathymetry of the research area, the GGM bathymetry shows correlation coefficients (CC) of 0.91, 0.92, and 0.85 with local shipborne sounding by KORDI, GEODAS, and a global ETOPO5 model, respectively. The enhanced GGM by selective merging shows imploved CCs of 0.948 and 0.954 with GEODAS and Smith & Sandwell (1997)'s predictions with RMS differences of 449.8 and 441.3 meters. The global marine FAGA data sets and other bathymetric models ensure that the GGM can be used in conjunction with shipborne bathymetry from echo sounding to extend the coverage into the unmapped regions, which should generate better results than simply gridding the sparse data or relying upon lower resolution global data sets such as ETOPO5.

• Archives of design research
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• v.17 no.1
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• pp.231-240
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• 2004

Space design in the 21st century has been developed in connection with media more various than ever. In the age of image represented by popular culture, space design connected with media is based on post-reason thoughts constituting the post-modern society, and reflects polysemously and pluralistically changes in the society through the identification of art with life. The movie, which is an image perceived particularly sensibly and the most impractical simulated image among various illusionary media images composing the contemporary society, is growing rapidly in interrelation with various fields of art based on its peculiar nature, and its influence is getting more extensive. The movie manipulates mass society to create what does not exist and restore lost images into new realities through the reproduction of extremely realistic senses, and uses them in establishing virtual realities and creating illusionary images representing the age of simularc. The illusionary expression of the movie produces new meanings through disintegrating existing meanings and recombining them, and expresses popular culture from a position closest to our everyday life. Such an analytical attitude toward the illusionary movie reflecting our society can be a new approach to space design. The present study attempts to suggest the possibility of applying such an illusionary characteristic of the movie as a methodology of space design by utilizing the characteristic as a conceptual language of space design.

• Polymer(Korea)
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• v.26 no.5
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• pp.691-700
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• 2002

Interstitial therapy using biodegradable polymeric device loaded with anticancer agent can deliver the drug to the tumor site at high concentration, resulting in an increase of therapeutic efficacy. 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, carmustine) is most commonly used as chemotherapeutic agent for brain tumors. The design of implantable device is regarded as an important factor lot the efficient delivery of antitumor agent to targeting site. In order to control the release profile of drug, the release pattern of BCNU with the changes of various dimension and additives was investigated. The PLGA wafers containing 3.85, 10, 20 and 30% of BCNU were prepared in various shape (diameter of 3, 5 and 10 mm, thickness of 0.5, 1 and 2 mm) by direct compression method. In vitro drug release profile of BCNU-loaded PLGA wafers could be controlled by changing the dimension of wafers such as initial drug content, weight, diameter, thickness, volume and surface area of wafers, as well as PLGA molecular weight and additives. Drug release from BCNU-loaded PLGA wafers was facilitated with an increase of BCNU-loading amount or presence of poly(N-vinylpyrrolidone)(PVP) or sodium chloride (NaCl). The effects of various geometric factors and additives on the BCNU release pattern were confirmed by the investigation of mass loss and morphology of BCNU-loaded PLGA wafers.

• Journal of the Korean Wood Science and Technology
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• v.37 no.6
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• pp.487-496
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• 2009

The sapwood of yellow poplar is very bright while its heartwood is usually greenish which changes to dark brown with weathering. This difference in color value between sapwood and heartwood causes difficulty in using yellow poplar as higher value added materials such as interior finish and furniture part. In this study, hot-water treatment, vacuum-heat treatment and oven-heat treatment were carried out to reduce the difference in color value between heartwood and bright sap wood and to increase durability. FT-IR analysis, contact angle measurement and decay test were carried out to find out the mechanism of functional group change and the increment of durability by heat treatment. The result of decrement ratio of color difference were 45.7% by hot-water treatment, 26.8% by vacuum-heat treatment, and 60.2%, 87.8%, and 88.8% by $180^{\circ}C$, $200^{\circ}C$ and $220^{\circ}C$ oven-heat treatments respectively. Furthermore, it has been found that oven-heat treatment causes decrement of mass loss by decay in this study. It is suggested that oven-heat treatment could be environmentally friendly preservative treatment without chemicals.