• Title/Summary/Keyword: Mass Production Phase

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- The Study on Emphasis Construction Plan for Efficient SRM(Supplier Relationship Management) System- (실용적인 SRM(Supplier Relationship Management) 시스템을 위한 중점구축 방안에 관한 연구)

  • Park Yung Ki;Yang Kwang Mo;Seo Jang Hun
    • Journal of the Korea Safety Management & Science
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    • v.6 no.3
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    • pp.175-186
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    • 2004
  • The compatibility of the enterprises of Korea was the 'low cost and mass production'. That in because, the entire business transactions including production, accounting, personnel management, and logistics need to be integrated with a global perspective. Logistics information system is to support the management of such logistics activities and involves in a wide range of the business operations. In other words, the logistics information system is 0 accurately and rapidly deliver and process the information available for the logistics in order to promote more smoother and efficient logistics by using such information. I'll give a brief introduction to the SRM(Supplier Relationship Management) system and go into the problem that should be considered and which phase to emphasize when building this system.

Study on the Measurement of $^{51}Cr-tagged$ Red Cell Survival - Reevaluation of its method & the effect of Blood loss on red cell suruival with $^{51}Cr$ - (방사성동위원소(放射性同位元素) $^{51}Cr$을 이용(利用)한 적혈구수명(赤血球壽命) 측정(測定)에 관(關)한 고찰(考察) -$^{51}Cr$-적혈구수명(赤血球壽命) 측정법(測定法)의 재평가(再評價)와 실혈(失血)이 수명측정(壽命測定)에 미치는 영향(影響)에 관(關)한 연구(硏究))

  • Choi, Hak-Yong;Koh, Chang-Soon;Lee, Moon-Ho
    • The Korean Journal of Nuclear Medicine
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    • v.4 no.2
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    • pp.55-66
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    • 1970
  • Reappraisal measurements of apparent half survival time of red cell by $^{51}Cr$ method was made and effects of blood-letting over red cell survival were observed. The study was performed on 53 normal male subjects under three different experimental conditions. 1. Group 1 Mean $^{51}Cr$ red cell half survival by ACD wash method was 29.7 days. $T\frac{1}{2}$ of Ascorbic acid method was 29.0 days in group with 100 mg dose and 29.1 days in group with 50 mg dose respectively. There was no difference between these two methods in regards to red cell half survival. No difference were noted in amount of ascorbic acid administered. 2. Group 2 As daily amount of blood loss is increased the shortening of red cell half survival was noted. Rapid phase was seen when blood loss ranged 10 to 25 ml per day, while slow phase noted when more loss amounted 25 ml or more daily. Thus, it was clear that there was more than an exponential relation between $T\frac{1}{2}$ and the amount of blood loss. 3. Group 3 $T\frac{1}{2}$ measured by cpm per whole blood was within normal range and $T\frac{1}{2}$ measured by cpm per red cell mass showed shortening tendency when compared with the former in the group measured after blood loss (from 25 ml daily up to 100 ml daily in 10 days). In the group with rather constant blood loss of 100 ml daily for 10 consecutive days revealed the significant difference in two measurements (P<0.01). 4. $T\frac{1}{2}$ in non-steady state When red cell production is increased compared with red cell destruction, $T\frac{1}{2}$ measured by cpm per red cell mass being shorter than that by cpm per whole blood. Shortening of $T\frac{1}{2}$ measured by cpm per whole blood is more prominent. if red cell destrction is enhanced and exceeds production. 5. It is clear that when expressing red cell destruction rate, $T\frac{1}{2}$ measured by cpm per whole blood is more adequate and production more consistent with cpm red cell mass. 6. $T\frac{1}{2}$ measured during blood-letting, when corrected by amount of blood loss, it remains normal. It is erroneous to use conventional equational when measuring $T\frac{1}{2}$ in non-steady. $T\frac{1}{2}$ measured by cpm per whole blood is considred more applicable in clinical evaluation.

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Effect of Housing Systems - Barn vs Cage on the First Phase Egg Production and Egg Quality Traits of Laying Pullet

  • Ahammed, Musabbir;Ohh, Sang Jip
    • Korean Journal of Poultry Science
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    • v.40 no.1
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    • pp.67-73
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    • 2013
  • With an increasing concern on laying hen welfare, barn system has appeared as one of the alternatives to replace the conventional cage. This study was conducted to compare the early laying performance and egg quality at the barn system with those at the conventional cage. A total of 288 shaver-579 brown layers were used for 9 weeks ($21^{st}$ to $30^{th}$ weeks of age) feeding study. Feed consumption and egg weight were significantly (P<0.01) higher at barn than at cage. However, there were no significant differences between two housing systems on hen day egg production (HDEP), egg mass, body weight, feed efficiency and livability. In case of egg quality parameters, shell thickness, albumen height and Haugh unit were significantly (P<0.05) different between two systems. Haugh unit and albumen height were significantly higher in eggs produced at cage (88.97 and 8.16 mm) compared than those produced at barn (83.11 and 6.87 mm), whereas shell thickness was thicker in eggs produced at barn than those produced at cage. Shape index, breaking strength, blood spots and yolk index data were not influenced significantly by the types of housing system. To implement welfare bestowing production, this study showed that the barn system can replace the conventional cage without serious sacrifices on starting phase egg production. In addition, this study suggested that the barn system need to be optimized in view of daily feed consumption.

The Long Term Effects of Fairly Low-level of Supplemental Fat on the Productive Performance of Commercial Layers

  • Bozkurt, Mehmet;Kucukyilmaz, Kamil;Cabuk, Metin;Catli, Abdullah Ugur
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.4
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    • pp.524-530
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    • 2012
  • Laying hens were fed commercial diets added with supplemented fat (SFAT) at 0.6, 1.2, and 1.8% in order to study the long term dietary effects - on - their productive performance from 22 to 75 wk of age. Five hundred and seventy six Single Comb White Leghorn hens were assigned to one of the four dietary treatments. The experimental phase consisted of three periods of 18 wk each. The final body weight and gain of hens fed on diets with SFAT at 1.2% and 1.8% were lower (p<0.05) than those hens given no SFAT. The SFAT at the 1.2% and 1.8% levels improved egg production rate, egg weight and mass, as well as FCR. Mortality and feed consumption were not affected by dietary SFAT. Administration of a diet with SFAT significantly decreased the cracked-broken egg ratio (p<0.01). The beneficial effects of SFAT on egg production performance were particularly more pronounced at intermediate and later ages. Hence, SFAT by period interactions were significant for all traits studied except feed intake. Hens fed SFAT deposited significantly higher abdominal fat than those on the no-SFAT diet. As a result, SFAT at 1.2% and 1.8% inclusion levels provided benefits in terms of efficient table egg production.

A Study on the Performance Analysis and Design of Cathode in Fuel Cells (연료전지 전극(Cathode)의 성능해석 및 설계에 관한 연구)

  • Kim, H.G.;Kang, S.S.;Song, H.Y.;Kang, Y.W.;Kwac, L.K.
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.16 no.1
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    • pp.75-79
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    • 2007
  • The cathode design is one of the most important parts in order to enhance the performance of fuel cells. A 3-D model of the porous oxygen reducing cathode with perforated current collectors is analysed for the enhanced design in fuel cells. Simulation is performed using equations of electric potential balance, momentum balance, and mass balance. The gas concentrations are quite large and are significantly affected by the reactions that take place. The weight fraction of oxygen, velocity field for the gas phase, and local overvoltage are illustrated in the porous reactive cathode layer. The current density is also analysed and the result shows the distribution and variation are stated in a wide range. It is found that the rate of reaction and the current production is higher beneath the orifice, and decreases as the distance to the gas inlet increases. The significance of the results is discussed in the viewpoint of the mass transportation phenomena, which is inferred that the mass transport of reactants dictates the efficiency of the electrode in this design and at these conditions.

Numerical and experimental studies of cryogenic reciprocating expander without inner piston

  • Park, Sehyeon;Bae, Junhyuk;Kim, Kyoungjoong;Jeong, Sangkwon
    • Progress in Superconductivity and Cryogenics
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    • v.20 no.3
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    • pp.21-27
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    • 2018
  • It is difficult to fabricate and maintain moving parts of expander at cryogenic temperature. This paper describes numerical analysis and experimental investigation on a cryogenic reciprocating expander without moving piston. An intake valve which takes high-pressure gas, and an exhaust valve which discharges low-pressure gas, are connected to a tube. The inside pressure of the tube is pulsated for work production. This geometric configuration is similar to that of pulse tube refrigerator but without regenerator. An orifice valve and a reservoir are installed to control the phase of the mass flow and the pressure. At the warm end, a heat exchanger rejects the heat which is converted from the produced work of the expanded gas. For the numerical analysis, mass conservation, energy conservation, and local mass function for valves are used as the governing equations. Before performing cryogenic experiments, we carried out the expander test at room temperature and compared the performance results with the numerical results. For cryogenic experiments, the gas is pre-cooled by liquid nitrogen, and then it enters the pulse tube expander. The experiments are controlled by the opening of the orifice valve. Numerical analysis also found the expander conditions that optimize the expander performance by changing the intake pressure and valve timing as well as the opening of the orifice valve. This paper discusses the experimental data and the numerical analysis results to understand the fundamental behavior of such a newly developed non-mechanical expander and elucidate its potential feature for cryogenic application.

A Morphological Study on the Titanium-Oxide Foams Processed Using Freeze-Casting (동결 주조법으로 제조된 티타늄 옥사이드 폼의 구조 연구)

  • Yoon, Hyunjung;Choe, Heeman;Choi, Hyelim
    • Journal of the Korean Ceramic Society
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    • v.49 no.5
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    • pp.427-431
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    • 2012
  • The $TiO_2$ foam synthesized using freeze-casting is a promising photocatalyst and photovoltaic electrode for a variety of energy applications, because the freeze-casting technique is easy to use, cheap, and suitable for mass-production. Despite its several advantages, little scientific information is available on the processing and morphology of the $TiO_2$ foams processed by freeze-casting. In particular, no systematic study has been performed on the microstructural evolution and morphological change of the rutile-phase $TiO_2$ foams during sintering. Therefore, in the present study, several $TiO_2$ foam samples were produced using the freeze-casting technique, which were then sintered at a relatively high temperature of $1200^{\circ}C$ for 1, 2, and 4 h to compare the morphological changes in the microstructure and to understand the effects of processing parameters of the rutile-phase $TiO_2$ foams. The foam ligament size increased near linearly with increasing sintering time whereas the average pore size decreased only slightly with increasing sintering time, with changes in particle morphology from sphere to rod and complete phase transformation from anatase to rutile.

The Fabrication of Gallium Phosphide Red Light Emitting Diode by Liquid Phase Epitaxy (갈륨인 단결정 성장으로 이룩한 적색 발광 다이오드의 제작)

  • 김종국;민석기
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.10 no.3
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    • pp.1-9
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    • 1973
  • Gallium phosphide light emitting diode (LED) has been fabricated first time for pilot lamp and numeric display purposes. Bright red light is obtained in forward bias at very low current of one to five mA. A typical p-n junction is formed by liquid phase epitaxial growth on a n-type gallium physphide substrate. The crystal growth is achieved at about 1300$^{\circ}$K after the equilibrium of the gallium solution followed by tipping operation. The ohmic contact is made by wire bonding by thermal compression technique. The entire process is well fit for laboratory scale to fabricate a few hundred diodes for mainly demonstration purpose. For mass production, a large sum of the capital investment is required. The great merit of gallium phosphide LED is at low current operation, and green light emission is also obtainable by nitrogen doping.

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On Coping with the Design Change Request by Utilizing DB Traceability in the Operational Phase of Safety-critical Weapon Systems (운영단계 안전중시시스템에서 제기되는 설계변경요구에 대해 아키텍처 DB의 추적성을 통한 변경프로세스의 개선)

  • Kim, Young Min;Lee, Jae-Chon
    • Journal of the Korea Safety Management & Science
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    • v.16 no.1
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    • pp.69-77
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    • 2014
  • The environment and requirements of modern war fields have been affected and thus changed by a variety of issues. To this end, the development of safety-critical weapon systems frequently need to meet those changes even in the operational phase. The necessity of the changes may be due to the preparation for mass-production or the request originated from the user military forces. To meet such a need can be even tougher in the development of safety-critical weapon systems since the integration of the requirements for both systems design and systems safety would make it troublesome. To handel the matter in this paper, utilization of architecture DB is proposed. Specifically, the situation in demand has first been analyzed and then a problem-solving process to accommodate the design changes has been constructed. In doing so, the concept of the aforementioned integration is particularly focused on the functional architecture, which could be a core concept of our approach to solving the problem. The result of a case study demonstrating the method studied using a computer-aided systems engineering tool is also presented.

Recombinant Glargine Insulin Production Process Using Escherichia coli

  • Hwang, Hae-Gwang;Kim, Kwang-Jin;Lee, Se-Hoon;Kim, Chang-Kyu;Min, Cheol-Ki;Yun, Jung-Mi;Lee, Su Ui;Son, Young-Jin
    • Journal of Microbiology and Biotechnology
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    • v.26 no.10
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    • pp.1781-1789
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    • 2016
  • Glargine insulin is a long-acting insulin analog that helps blood glucose maintenance in patients with diabetes. We constructed the pPT-GI vector to express prepeptide glargine insulin when transformed into Escherichia coli JM109. The transformed E. coli cells were cultured by fed-batch fermentation. The final dry cell mass was 18 g/l. The prepeptide glargine insulin was 38.52% of the total protein. It was expressed as an inclusion body and then refolded to recover the biological activity. To convert the prepeptide into glargine insulin, citraconylation and trypsin cleavage were performed. Using citraconylation, the yield of enzymatic conversion for glargine insulin increased by 3.2-fold compared with that without citraconylation. After the enzyme reaction, active glargine insulin was purified by two types of chromatography (ion-exchange chromatography and reverse-phase chromatography). We obtained recombinant human glargine insulin at 98.11% purity and verified that it is equal to the standard of human glargine insulin, based on High-performance liquid chromatography analysis and Matrix-assisted laser desorption/ionization Time-of-Flight Mass Spectrometry. We thus established a production process for high-purity recombinant human glargine insulin and a method to block Arg (B31)-insulin formation. This established process for recombinant human glargine insulin may be a model process for the production of other human insulin analogs.