• Title/Summary/Keyword: Mashhad

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Renoprotective Effect of Plantago major Against Proteinuria and Apoptosis Induced by Adriamycin in Rat

  • Yazd, Zohreh Naji Ebrahimi;Noshahr, Zahra Samadi;Hosseinian, Sara;Shafei, Mohammad Naser;Bideskan, Alireza Ebrahimzadeh;Mohebbati, Reza;Heravi, Nazanin Entezari;Shahraki, Samira;Mahzari, Somayeh;Rad, Abolfazl Khajavi
    • Journal of Pharmacopuncture
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    • v.22 no.1
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    • pp.35-40
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    • 2019
  • Objective: Adriamycin (ADR) is an important anti-cancer drug which can cause renal toxicity. Given the known anti-inflammatory and antioxidant effects of Plantago major (P. major), the aim of this study was to determine the effects of hydroalcoholic extract of P. major on ADR- induced nephropathy in rats. Methods: Fifty male Wistar albino rats were randomly divided into 5 groups including: control, ADR (5 mg/kg), ADR + P. major (600 and 1200 mg/kg) and P. major (1200 mg/kg). The animals were treated with P. major extract for 5 consecutive weeks and ADR was intravenously injected on the 7th day of the study. Urine and serum samples were collected on days 0, 14, 21, 28, and 35 for the measurement of serum cholesterol and albumin levels and urine protein excretion rate. At the end of the study, the left kidneys were removed for apoptosis assessment. Results: Administration of ADR significantly decreased serum albumin level and increased serum cholesterol and urine protein excretion rate as well as, apoptotic cell numbers compared to the control group (P < 0.001) while had no effect on glomerular filtration rate (P > 0.05). Treatment with P. major, in both 600 and 1200 mg/kg doses, increased serum albumin level and decreased serum cholesterol concentration, urine protein excretion rate and as well as the number of apoptotic cell compared to the ADR group (P < 0.001). Conclusion: Our results showed that the P. major extract effectively protects against ADR- induced nephropathy by reducing kidney apoptosis and improving renal functioning in rats.

Fe(HSO4)3 as an Efficient Catalyst for Diazotization and Diazo Coupling Reactions

  • Rahimizadeh, Mohammad;Eshghi, Hossein;Shiri, Ali;Ghadamyari, Zohreh;Matin, Maryam M.;Oroojalian, Fatemeh;Pordeli, Parvaneh
    • Journal of the Korean Chemical Society
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    • v.56 no.6
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    • pp.716-719
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    • 2012
  • Diazo coupling reactions of aromatic amines with 2-naphthol in a green, efficient and easy procedure is described. Ferric hydrogensulfate catalyses this reaction in water at room temperature and short reaction time with high yields. The antibacterial activities of the synthesized compounds against four pathogenic bacteria are also investigated.

Determining the Optimum Brands Diversity of Cheese Using PSO (Case Study: Mashhad)

  • Dadrasmoghadam, Amir;Ghorbani, Mohammad;Karbasi, Alireza;Kohansal, Mohammad Reza
    • Industrial Engineering and Management Systems
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    • v.15 no.4
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    • pp.318-323
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    • 2016
  • In the current study, factors affecting cheese brands products in grocery stores were evaluated with an emphasis on diversity. The sample data were collected from Noushad and Pegah Milk Industry in 2015 and data were extracted, reviewed, and analyzed from 435 grocery stores in Mashhad using seemingly unrelated regression model and particle swarm optimization algorithm. Results showed that optimum amount of Kalleh product diversity is higher than other competitors in the market, and Kalleh UF diversity is 100 to 250 grams, and Kalleh UF diversity with weight of 300 to 500 grams is more than other modes of diversity, and Kalleh brand must remove tin cheese from the market. Sabah Brand also should eliminate its glass and creamy diversity from market, UF diversity is mostly welcomed in market.

SHARPENING LOWER BOUND IN SOME INEQUALITIES FOR FRAMES IN HILBERT SPACES

  • Sultanzadeh, Fahimeh;Hassani, Mahmood;Omidvar, Mohsen Erfanian;Gol, Rajab Ali kamyabi
    • Korean Journal of Mathematics
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    • v.29 no.4
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    • pp.725-732
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    • 2021
  • This paper aims to present a new lower bound for some inequalities related to Frames in Hilbert space. Some refinements of the inequalities for general frames and alternate dual frames under suitable conditions are given. These results refine the remarkable results obtained by Balan et al. and Gavruta.