• Journal of Digital Contents Society
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• v.18 no.8
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• pp.1627-1633
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• 2017

Human dance is difficult to learn since there is no effective way to imitate an expert's motion, a sequence of complicated body movements, without taking an actual class. In this paper, we propose a dance learning system using human depth information. In the proposed system, a set of example motions are captured from various expert dancers through a marker-free motion capture and archived into a motion database server for online dance lessons. Given the end-user devices such as tablet and kiosk PCs, a student can learn a desired motion selected from the database and send one's own motion to an instructor for online feedback. During this learning process, our system provides a posture-based motion search and multi-mode views to support the efficient exchange of motion data between the student and instructor under a networked environment. The experimental results demonstrate that our system is capable to improve the student's dance skills over a given period of time.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.7
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• pp.629-636
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• 2009

Mechanical stimulation is known to play a vital role on the differentiation of mesenchymal stem cells (MSCs) to pre-osteoblasts. In this research, we developed a tensile cell stimulator, composed of a DC motor-driven actuator and LVDT sensor for measuring linear displacement, to study the effects of tensile stress on osteogenic differentiation of MSCs. First, we demonstrated the reliability of this device by showing the uniform strain field in the silicon substrate. Secondly, we investigated the effects of tensile stretching on osteogenic differentiation. We imposed a pre-set cyclic strain at a fixed frequency on cell monolayer cultured on a flexible silicon substrate while varying its amplitude and duration. 60 min of resting period was allowed between 30 min of cyclic stretching and this cycle is repeated up to 7 days. Under the combined stimulation with osteogenic media and mechanical stretching, the osteogenic markers such as alkaline phosphatase (ALP), osterix, and osteopontin began to get expressed as early as 4 days of stimulation, which is much shorter than what is typically required for osteogenic media induced differentiation. Moreover, different markers were induced at different magnitudes of the applied strains. Lastly, for the case of ALP, we observed the antagonistic effects of osteogenic media when combined with mechanical stretching.

• YAKHAK HOEJI
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• v.56 no.5
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• pp.280-287
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• 2012

A high-performance liquid chromatography (HPLC) combined with ultraviolet (UV) method for the simultaneous determination of ${\alpha}$-cyperone and nootkatone was developed for the quality control of Cyperus rotundus Linne. The separation was performed on a KR100-$5C_{18}$ ($4.6{\times}250mm$) column, and an elution gradient composed of methanol and water with a flow-rate of 1.0 ml/min. Detection wavelength was set at 254 nm. The optimum extraction for the detection of the ${\alpha}$-cyperone and nookatone was achieved by ultrasonic with methanol for an hour. Two marker compounds ${\alpha}$-cyperone and nootkatone in Cyperi Rhizoma showed good linearity ($R^2$ >0.999) in the concentration range of $12.5{\mu}g/ml$ to $200{\mu}g/ml$. The developed method provided satisfactory precision and accuracy with overall intra-day and inter-day variations of 0.04~1.23% and 0.08~0.68%, respectively, and the overall recoveries of 97.45~105.58% for the two compounds analyzed. Additionally, a difference was observed in the cluster analysis and principal component analysis between Cyperi Rhizoma in Korea and China. The result demonstrated that the principal component analysis is useful to distinguish between Cyperi Rhizoma in Korea and China.

• Korean Journal of Medicinal Crop Science
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• v.24 no.2
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• pp.93-100
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• 2016

Background: A set of logical criteria that can accurately identify and verify the cultivation region of raw materials is a critical tool for the scientific management of traditional herbal medicine. Methods and Results: Volatile compounds were obtained from 19 and 32 samples of Angelica gigas Nakai cultivated in Korea and China, respectively, by using steam distillation extraction. The metabolites were identified using GC/MS by querying against the NIST reference library. Data binning was performed to normalize the number of variables used in statistical analysis. Multivariate statistical analyses, such as Principal Component Analysis (PCA), Partial Least Squares-Discriminant Analysis (PLS-DA), and Orthogonal Partial Least Squares-Discriminant Analysis (OPLS-DA) were performed using the SIMCA-P software. Significant variables with a Variable Importance in the Projection (VIP) score higher than 1.0 as obtained through OPLS-DA and those that resulted in p-values less than 0.05 through one-way ANOVA were selected to verify the marker compounds. Among the 19 variables extracted, styrene, ${\alpha}$-pinene, and ${\beta}$-terpinene were selected as markers to indicate the origin of A. gigas. Conclusions: The statistical model developed was suitable for determination of the geographical origin of A. gigas. The cultivation regions of six Korean and eight Chinese A. gigas. samples were predicted using the established OPLS-DA model and it was confirmed that 13 of the 14 samples were accurately classified.

• Korean Journal of Health Education and Promotion
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• v.19 no.3
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• pp.121-133
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• 2002

The purpose of this study was to set up the basic model to monitor the health status of the middle and high school students in the adolescent period, as well as to provide the fundamental data which might serve as the new standards for their better health maintenance and promotion. The collected data comprised the characteristics of the subjects in the three different fields of life such as school, family and everyday, which could affect their physical fatigues, and they were analyzed to determine the factors of significant influence upon their physical fatigues and to reveal their relativity. A total of 5,954 students at 6 boys' and girls' middle and high schools in Taejon City completed self-administered questionnaires(to measure Health Practice Index and others) asking about each of three life domains during the period March through June, 2000. The key study results were as follows; 1. The middle school students showed more subjective symptoms of fatigue which may be a marker reflecting physical health status, than the high school students. The higher scores were associated, based on school life, with the groups who were boys, who were in lower school grades, who achieved better academic performances and had better relationship with friends. 2. As for family life, the higher scores were in the groups whose financial conditions were better, whose parents showed more interest to their children, whose sense of satisfaction with family life was higher, and whose health status was better. 3. As for life styles, the individuals showed the higher scores in the groups who had breakfasts daily, who didn't have inter-meal snacks, who took regular exercises, who didn't smoke and drink than, their counterparts. 4. The higher level of fatigue was associated with the groups whose health conditions were good, who are satisfied with school life, who were boys rather than girls, who are satisfied with family life, who didn't have inter-meal snacks, who were in good relationship with friends, who achieved greater academic performances, who took regular exercises, who didn't smoke, and whose parents showed more interest in their children.

• Genomics & Informatics
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• v.8 no.3
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• pp.138-141
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• 2010

Together with single nucleotide polymorphism (SNP), copy number variations (CNV) are recognized to be the major component of human genetic diversity and used as a genetic marker in many disease association studies. Affymetrix Genome-wide SNP 5.0 is one of the commonly used SNP array platforms for SNP-GWAS as well as CNV analysis. However, there has been no report that validated the accuracy and reproducibility of CNVs identified by Affymetrix SNP array 5.0. In this study, we compared the characteristics of CNVs from the same set of genomic DNAs detected by three different array platforms; Affymetrix SNP array 5.0, Agilent 2X244K CNV array and NimbleGen 2.1M CNV array. In our analysis, Affymetrix SNP array 5.0 seems to detect CNVs in a reliable manner, which can be applied for association studies. However, for the purpose of defining CNVs in detail, Affymetrix Genome-wide SNP 5.0 might be relatively less ideal than NimbleGen 2.1M CNV array and Agilent 2X244K CNV array, which outperform Affymetrix array for defining the small-sized single copy variants. This result will help researchers to select a suitable array platform for CNV analysis.

• Journal of KIISE:Computing Practices and Letters
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• v.16 no.11
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• pp.1131-1135
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• 2010

This paper presents a method to capture the posture of the human lower-limbs on the 3D space by using a single camera and a planar mirror. The system estimates the pose of the camera facing the mirror by using four coplanar IR markers attached on the planar mirror. After that, the training space is set up based on the relationship between the mirror and the camera. When a patient steps on the weight board, the system obtains relative position between patients' feet. The markers are attached on the sides of both legs, so that some markers are invisible from the camera due to the self-occlusion. The reflections of the markers on the mirror can partially resolve the above problem with a single camera system. The 3D positions of the markers are estimated by using the geometric information of the camera on the training space. Finally the system estimates and visualizes the posture and motion of the both legs based on the 3D marker positions.

• Journal of the Korean Institute of Intelligent Systems
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• v.16 no.3
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• pp.332-337
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• 2006

It has been suggested that the endoscopic color of intramucosal gastric carcinoma is correlated with mucosal vascularity within the carcinomatous tissue. The development of electronic endoscopy has made it possible to quantitatively measure the mucosal hemoglobin volume, using a hemoglobin index. The aim of this study was to make a software program to calculate the hemoglobin index (IHb) and then investigate whether the mucosal IHb determined from the electronic endoscopic data is a useful marker for evaluating the color of intramucosal gastric carcinoma, in particular with regard to its value for discriminating between the histologic types. The mean values of IHb for the carcinoma (IHb-C) and the mean values of IHb for the surrounding non-cancerous mucosa (IHb-N) were calculated in 75 intestinal-type and 34 diffuse-type gastric carcinomas. Then, we analyzed the ratio of the IHb-C to IHb-N. The mean IHb-C/IHb-N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group (1.28$\pm$0.19 vs. 0.81$\pm$0.18, respectively, p<0.001). When the cut-off point of the C/N ratio was set at 1.00, the accuracy rate, the sensitivity, the specificity, and the positive and negative predictive values of a C/R ratio below 1.00 for the differential diagnosis of diffuse-type carcinoma from intestinal-type carcinoma were 94.5%, 94.1%, 94.7%, 88.9% and 97.3%, respectively. IHb is useful for quantitative measurement of the endoscopic color in intramucosal gastric carcinoma and the IHb-C/IHb-N ratio would be helpful in distinguishing diffuse-type carcinoma from intestinal-type carcinoma.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.117-123
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• 2021

The purpose of this study is to convergence comparison the ankle joint angle change during walking of college students in their 20s with flat foot according to the heel height of insole shoes. Qualisys Track Manager Software ver. 2.8 (Qalisys Track Manager) was used for 15 college students. Functional shoes with insoles were manufactured, and the heel heights of the shoes were set to 3cm and 7cm. The subjects wore shoes with two high heels and gaited by attaching a reflex marker to the side of the ankle joint. The angle change of the ankle joint was measured in the gait stance phase. The angle of the ankle joint significantly decreased both heel strike, foot flat, midstance, and toe off to the heel height increased when the subjects with flat feet wore insole shoes. Therefore, it is thought that flat feet should wear low shoes when wearing insoles to reduce the fatigue of the soles and to walk comfortably.

• Analytical Science and Technology
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• v.32 no.4
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• pp.139-146
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• 2019

A simple and reliable analytical method based on high-performance liquid chromatography-ultraviolet detection was established for the analysis of the flowers of Chrysanthemum morifolium (CM). Luteolin-7-O-glucoside (LU7G) was chosen as a target analyte considering its content, availability, and ease of analysis. Chromatographic separation of LU7G was achieved using a Phenomenex Gemini $C_{18}$ column ($250{\times}4.6mm$, $5{\mu}m$) run with a mobile phase consisting of 0.5 % acetic acid in water and 0.5 % acetic acid in acetonitrile at a flow rate of $1.0mL\;min^{-1}$. The detection wavelength and column temperature were set at 350 nm and $40^{\circ}C$, respectively. Method validation was performed according to the AOAC guidelines and the method was specific, linear ($R^2=0.9991$ for $50-300{\mu}g\;mL^{-1}$), precise (${\leq}3.91%$RSD), and accurate (100.1-105.7 %). The limits of detection and quantification were 3.62 and $10.96{\mu}g\;mL^{-1}$, respectively. The established method was successfully applied to determine the contents of LU7G in various batches of bulk CM extracts and labscale CM extract. The developed method is a readily applicable method for the quality assessment of CM and its related products.