• Title/Summary/Keyword: Marker component

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Quality Evaluation of Alismatis Rhizoma by High Performance Liquid Chromatography

  • Lee Sang-Myung;Kang Jong-Seong;Hwang Gwi-Seo;Kim Young-Ho;Lee Cheal-Gyu;Yeo Woon-Hyung;Bae Ki-Hwan
    • Archives of Pharmacal Research
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    • v.27 no.4
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    • pp.460-464
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    • 2004
  • The quality of Alismatis Rhizoma was evaluated by reversed-phase high performance liquid chromatographic method. Alisol B 23-acetate was used as a standard marker for evaluation. This component was fully separated from the other components in the plant extracts on a ODS column. Identifcation of alisol B 23-acetate was carried out by comparing the LC/MS spectrum of separated peak from the extract with that of standard. Alisol B 23-acetate contents in Alismatis Rhizoma obtained from several herbal markets were varied from $0. 15\%$ to $0.56\%$.

RGISS: Rice (Oryza sativa L. ssp. japonica) Genome Information Service System

  • Lee, Dae-Sang;Seo, Hwa-Jung;Hahn, Jang-Ho;Kong, Eun-Bae;Park, Kie-Jung
    • Genomics & Informatics
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    • v.5 no.4
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    • pp.194-195
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    • 2007
  • We have constructed the Rice Genome Information Service System (RGISS), which is an information service system of the Oryza sativa L. ssp. japonica (rice) genome, using the released version of rice Build 3.0 pseudomolecules based on the Ensembl architecture. The nonredundant library, composed of 3,360 clones of BACs, PACs, and fosmids, was used to construct supercontigs. RGISS contains 50,717 annotated genes from GenBank, 56,161 predicted genes from FgeneSH, and information on 9,587 markers, which includes STS, SSR, and EST-based RFLP. The 20,180 ESTs sequenced by the Korea National Institute of Agricultural Biotechnology (NIAB) were aligned and mapped into 168,792 exons. By gene ontology analysis, the classified protein numbers in the rice genome were 6158, 4531, and 12,364 proteins, which were mapped to molecular function, cellular component, and biological process, respectively.

ESTIMATING THE MOTION OF THE HUMAN JOINTS USING OPTICAL MOTION CAPTURE SYSTEM

  • Park, Jun-Young;Kyota, Fumihito;Saito, Suguru;Nakajima, Masayuki
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2009.01a
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    • pp.764-767
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    • 2009
  • Motion capture systems allow to measure the precise position of markers on the human body in real time. These captured motion data, the marker position data, have to be fitted by a human skeleton model to represent the motion of the human. Typical human skeleton models approximate the joints using a ball joint model. However, because this model cannot represent the human skeleton precisely, errors between the motion data and the movements of the simplified human skeleton model happen. We propose in this paper a method for measuring a translation component of wrist, and elbow joints on upper limb using optical motion capture system. Then we study the errors between the ball joint model and acquired motion data. In addition, we discuss the problem to estimate motion of human joint using optical motion capture system.

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Work Load Dependency of Heart Rate Variability (HRV) (심박변이도의 운동부하 의존성)

  • Kwon J.H.;Kim C.S.;Eom G.M.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.641-642
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    • 2006
  • The purpose of this work is to investigate the effect of work load on heart rate variability (HRV) which is widely used marker of the autonomic nervous system activity. Average heart rate, rating of perceived exertion, and the power spectrum of heart rate variability were investigated in seven healthy males during exercise at various work loads. The subjects were divided into two groups according to the average heart rate during exercise, group 1 with lower heart rate and group 2 with higher heart rate. HF component showed decrease followed by increase with workload. Accordingly, the LF/HF ratio showed increase followed by decrease with workload. The peak in LF/HF ratio of group 1 was at the lower workload than that of group 2.

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The Statistical Evaluation for the Wear Life of Brake Pad Linings in Vehicle Durability Test and Customer Usage Environment (차량내구시험과 시장 사용환경에서의 브레이크 패드 마찰재 마모수명에 대한 통계적 평가)

  • 서경원;정관영
    • Transactions of the Korean Society of Automotive Engineers
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    • v.7 no.5
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    • pp.213-220
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    • 1999
  • The life data analysis of the system and component are useful to describe the result of reliability test in product life to satisfy customer's growing need and to change test specifications or design criteria by life data analysis. And vehicle durability tesr occurred market environment. In this study, a statistical analysis for the wear life of brake pad linings helped perform correlation procedure between vehicle durability test and market. B-life values of the brake pad wear life data from both vehicle durability test and marker usage were compared to determine acceleration of the test by the Weibull, normal and log-normal distribution. The acceleration coefficient of the vehicle durability test can access to evaluate design criteria of product and test specification.

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Recent Methodology in Ginseng Analysis

  • Baek, Seung-Hoon;Bae, Ok-Nam;Park, Jeong-Hill
    • Journal of Ginseng Research
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    • v.36 no.2
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    • pp.119-134
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    • 2012
  • As much as the popularity of ginseng in herbal prescriptions or remedies, ginseng has become the focus of research in many scientific fields. Analytical methodologies for ginseng, referred to as ginseng analysis hereafter, have been developed for bioactive component discovery, phytochemical profiling, quality control, and pharmacokinetic studies. This review summarizes the most recent advances in ginseng analysis in the past half-decade including emerging techniques and analytical trends. Ginseng analysis includes all of the leading analytical tools and serves as a representative model for the analytical research of herbal medicines.

A Marker Detection and Recognition System based on Principal Component Analysis (주성분 분석을 이용한 마커 검출 및 인식 시스템)

  • Kang, Sun-Kyoung;So, In-Me;Kim, Young-Un;Jung, Sung-Tae
    • Proceedings of the Korea Information Processing Society Conference
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    • 2006.11a
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    • pp.129-132
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    • 2006
  • 본 논문에서는 카메라 영상으로부터 사각형 형태의 마커를 검출하고 인식하는 방법을 제안한다. 본 논문에서는 사각형 형태의 마커 검출을 위하여 입력 영상을 이진 영상으로 변환하고 객체들의 윤곽선을 추출한 다음에 윤곽선을 선분으로 근사화 한다. 근사화된 선분으로부터 기하학적 특징을 이용하여 사각형을 찾는다. 마커의 사각형 영역을 찾은 다음에는 워핑 기법을 이용하여 사각형 마커 영상으로부터 특징 벡터를 추출하고 표준 마커에 대한 특징 벡터와의 최소 거래법에 의해 마커의 종류를 인식한다. 인식 실험 결과 마커의 종류가 50개일 때에 최대 98%의 인식률을 얻을 수 있었다.

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Effects of Malloti Cortex Water Extract, Bergenin, and Acetylbergenin on Liver Fibrosis Induced by Bile Duct Ligation in Rats

  • Chung, Myeon-Woo;Sunoo, Sub;Kim, Seung-Hwan;Kim, Hack-Seang
    • Biomolecules & Therapeutics
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    • v.9 no.2
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    • pp.112-118
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    • 2001
  • The effects of Malloti Cortex Water Extract (MCWE), bergenin (isolated as an active component from MCWE), and acetylbergenin (synthesized from acetylation of bergenin) on the liver fibrosis induced by bile duct ligation (BDL) in rats. We studied hydroxypro1ine (HYP) as a marker of collagen accumulation in the liver, alanine aminotransferase (s-ALT), aspartate aminotransferase (s-AST), and alkaline phosphatase (s-ALP) as serum markers of liver cell damage induced by BDL, MCWE, bergenin, and acetylbergenin decreased towards normal the accumulated levels of HYP in the liver and the elevated serum levels of s-ALT, s-AST and 5-ALP. The results indicate that MCWE, bergenin, and acetylbergenin ameliorated the liver damage induced by BDL in rats.

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The Emerging Role of Fast MR Techniques in Traumatic Brain Injury

  • Yoo, Roh-Eul;Choi, Seung Hong
    • Investigative Magnetic Resonance Imaging
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    • v.25 no.2
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    • pp.76-80
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    • 2021
  • Post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) is a major factor that contributes to the increased socioeconomic burden caused by TBI. Myelin loss has been implicated in the development of PCS following mTBI. Diffusion tensor imaging (DTI), a traditional imaging modality for the evaluation of axonal and myelin integrity in mTBI, has intrinsic limitations, including its lack of specificity and its time-consuming and labor-intensive post-processing analysis. More recently, various fast MR techniques based on multicomponent relaxometry (MCR), including QRAPMASTER, mcDESPOT, and MDME sequences, have been developed. These MCR-based sequences can provide myelin water fraction/myelin volume fraction, a quantitative parameter more specific to myelin, which might serve as a surrogate marker of myelin volume, in a clinically feasible time. In this review, we summarize the clinical application of the MCR-based fast MR techniques in mTBI patients.

Functional analysis of the antioxidant activity of immune-challenged Bombyx mori hemolymph extracts in the human epithelial Caco-2 cell line

  • Kim, Seong Ryul;Kim, Kee-Young;Kim, Seong-Wan;Park, Seung-Won
    • International Journal of Industrial Entomology and Biomaterials
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    • v.40 no.1
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    • pp.16-21
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    • 2020
  • Humans use insects as food and traditional medicine for many years. Hemolymph is the circulating fluid of insects and is a key component of their immune system. However, limited information is available regarding hemolymph identification, development, and differentiation, as well as the related cellular immune responses. In a previous study, hemolymph extracts prepared from Bombyx mori larvae were found to exert anti-inflammatory effects. In this study, we aimed to identify and compare the antioxidant activity of immune-challenged and unchallenged B. mori hemolymph extracts in vitro. For this purpose, human epithelial Caco-2 cells were first exposed to oxidative stress and then treated with various concentrations and incubation times of either immune-challenged or unchallenged B. mori hemolymph extracts. Next, we determined the effect of treatment on the relative expression of GPX-1, SOD-1, and SOD-2 antioxidant marker genes. We found that the expression rates of the three marker genes were markedly higher at a immune-challenged hemolymph extract concentration of 80 ppm compared to those at other concentrations, and the antioxidant effects were enhanced after treatment for 48 hr. Thus, B. mori hemolymph extracts showed antioxidant activity within the limited time and dose. Especially, the immune-challenged B. mori hemolymph extracts showed higher the antioxidant activities than unchallenged one. The activity of silkworm hemolymph extracts could facilitate the development of new types of functional foods, feed additives, and biomaterials with antioxidant properties.