• Title/Summary/Keyword: Mark

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PDGFC, MARK3 and BCL2 Polymorphisms are Associated with Left Ventricular Hypertrophy in Korean Population

  • Jeon, Tae-Eun;Jin, Hyun-Soek
    • Biomedical Science Letters
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    • v.25 no.3
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    • pp.237-246
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    • 2019
  • Left ventricular hypertrophy (LVH) refers to the expansion and the enlarged myocardium due to the increased resistance to ejection from the left ventricle to the aorta and/or the periphery, or the long-term burden imposed by the blood increase. Hypertension is a major risk factor that accounts for more than 50% of the causes of cardiovascular disease. If hypertension endure in the long term, the myocardium responds to abnormal heartbeat in the heart. Therefore, the prevalence of left ventricular hypertrophy also increases. As a result of genome-wide association study (GWAS) analysis for European people, PDGFC, MARK3, and BCL2 were related to blood pressures. In this study, the genetic polymorphisms of PDGFC, MARK3, and BCL2 were extracted and selected based on Korean genomic and epidemiologic data, and then logistic regression analysis was performed on LVH. As a result, one SNP (rs9307953) in PDGFC gene, four SNPs (rs6575983, rs17679475, rs2273703 and rs10141388) in MARK3 gene and two SNPs (rs17756073 and rs17070739) in BCL2 gene were statistically significant. The rs6575983 of the MARK3 gene showed the highest significance level ($P=7.2{\times}10^{-3}$) among the SNPs and the relative risk of 1.08 (95% confidence interval: 1.06 to 1.45). These results suggest that the polymorphisms of PDGFC, MARK3, and BCL2 not only affect European blood pressures but also correlate with LVH in Korean. These results suggest that increased understanding of the genetic correlations of the pathogenesis of LVH.

Brand Mark and Station Identification for TV Channel Specializing in Childcare for House Husbands (가사전담 남편을 위한 육아 TV채널의 브랜드마크 및 스테이션 아이덴티피케이션 제안)

  • Chun, Eunyoung;Choi, Jangseop;Paik, Jinkyung
    • Design Convergence Study
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    • v.15 no.3
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    • pp.103-116
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    • 2016
  • Social development led to systematic changes in the gender division of housework and the increase of house husbands. Accordingly, the demand for programs on child rearing for fathers is high. This study aimed to present a design for the brand mark and station identification for a TV channel specializing in childcare for house husbands. This study designed a brand mark and an applied brand mark, based on a literary review of previous studies. A survey on the necessity, preference and brand awareness of this channel was conducted twice afterwards, targeting 55 parents who are raising children who are in between the age of 6 months to 37 months. The first survey showed that the parents are in need of childcare-related channels due to their worries and fear towards childcare. When asked about their preferences and brand awareness towards this channel, some respondents were negative towards the form and colors used in the proposed brand mark and applied brand mark. This was reflected in the improved version and was tested in the second survey, which showed that respondents preferred the form that reminded them of children and found it more suitable. In regards to colors, respondents preferred high chroma navy blue.

A study on the O'Leary index and dental plague index of dental patients (치과내원 환자의 올리어리(O'Leary) 지수와 개별치아의 치면세균막 지수에 관한 연구)

  • Park, Sung-Suk;Cho, Pyeong-Kyu
    • Journal of Korean society of Dental Hygiene
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    • v.9 no.3
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    • pp.426-438
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    • 2009
  • The purpose of this study was to examine the relationship of the general characteristics of dental patients to their total O'Leary index and individual plaque indexes in a bid to check the oral hygiene state of citizens and evaluate their plaque management ability. The subjects in this study were 288 patients at dental hospitals and clinics in Busan and South Gyeongsang Province. A survey was conducted from September to November 2008. The findings of the study were as follows: 1. Overall, the O'Leary index of the patients investigated stood at 72 percent. By age and gender, the O'Leary index was highest among those in their 30s(83%) and among the women(75%)(p<.05). As to the influence of toothbrushing frequency, the patients who did it twice or more a day had the highest O'Leary index(75%)(p<.001). By the use of oral hygiene supplies, the patients who used oral hygiene supplies had a higher O'Leary index(76%) than the others who didn't(p<.01). 2. As for plaque index for each tooth, 28 percent of their teeth were given zero point, and 52 percent were given one mark. 13 percent were given two marks, and 6.3 percent were given three marks. Thus, the teeth that were given one mark were largest in number(p<.001). 3. As for plaque index for labial posterior mandibular, 43 percent of their teeth were given one point, and 36 percent were given zero mark. 14 percent were given three mark, and 5 percent were given three marks(p<.01). 4. As for plaque index for buccal posterior maxilla, 57 percent of their teeth were given one point, and 20 percent were given zero mark. 16 percent were given two mark, and 6.3 percent were given three marks(p<.01). 5. As for plaque index for lingual posterior mandibular, 56 percent of their teeth were given one point, and 27.8 percent were given zero mark. 9 percent were given three mark and 6 percent were given three mark(p<.001).

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The Relay Circuits Translation to EMFGs (릴레이 회로의 확장된 마크흐름선도 변환)

  • 여정모;백형구
    • Journal of Institute of Control, Robotics and Systems
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    • v.9 no.11
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    • pp.952-957
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    • 2003
  • We propose how to translate relay circuits to the EMFGs(Extended Mark Flow Graphs) formally and analyze the original one by using the mark flow of it. Firstly, the concepts of the output condition, the output-on condition and the output-off condition are introduced in the relay circuits. These can be used to find the structure and the operation of respective relay outputs but the sequential operations of them cannot be obtained from these. Secondly, a relay circuit is translated to the corresponding EMFG as the all output-on conditions and all output-off conditions of it are translated to EMFGs. For the adequate translation, the condition arc and the concepts of the generation transition and the degeneration transition are introduced, and the duality for the simplification of the result. Thirdly, we analyze the operation of the original circuit by analyzing the mark flow of the resulting EMFG. We can achieve easy and fast analysis based on the EMFG's operation algorithm. Finally, we apply these to the relay circuit for an electric furnace and analyze its operation with the mark flow of the resulting EMFG. The formal translation from relay circuits to EMFGs makes the analysis easy so that these results can be used to design, modelling, the fault detection and the maintenance.

Design and Evaluation of Corporate Identity Symbol Marks by Hybrid Kansei Engineering (혼합형 감성공학에 의한 CI 심벌마크의 설계 및 평가)

  • 장인성;박용주
    • Journal of Intelligence and Information Systems
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    • v.7 no.2
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    • pp.129-141
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    • 2001
  • Kansei engineering or image technology is a tool to analyze relation between product design components and the impression or feeling of human for physical products. This paper attempts to construct the designer\`s aid tool for developing corporate identity(CI) symbol mark based on the hybrid Kansei engineering. It combines the forward Kansei engineering for translating consumer\`s feeling into design components of CI symbol mark and the backward Kansei engineering for evaluating consumer\`s feeling for CI symbol mark. The semantic differential(SD) evaluation experiment is carried out to find the relations between image and design. The backward Kansei engineering system is modelled by fuzzy neural network. This research is expected to contribute to the development of CI symbol mark that correspond to comsumer\`s image.

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Development of Automatic Mark Welding Robot

  • Ryu, Sin-Wook;Kim, Ho-Gu;Lee, Jae-Chang;Kim, Se-Hwan
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.643-648
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    • 2005
  • Generally, ships have marks of various shapes on outside of the hull. Among them, so called "Draft Mark" indicates the distance from the bottom of the keel to the waterline. Draft marks are used to determine the displacement and other properties of the ship for stability and control purposes. These marks are made up of welding bead or sticking the steel plate on outside of the hull. To improve the confidence level of the ship owner, quality and accuracy of the draft mark is very important. So the automatic mark welding robot is used to enable a high quality and accurate manufacturing line. To improve the system portability, the system is divided into two distinct parts, namely mechanical part and control part. Mechanical part is robust, a lightweight, and easy to dismantle. The control part consists of an in-house developed controller, which is based on embedded Linux. Also, the control part consists of power line communication module to ensure the applicability of the controller in manufacturing line. In this paper, the methodologies of control and configuration of the robot are discussed.

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A Study on the Color Extendability in Mark Rothko's Color-Field Abstract (마크 로드코의 색면추상에 표현된 색의 확장성 연구)

  • Kim, Sun-Young
    • Korean Institute of Interior Design Journal
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    • v.22 no.1
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    • pp.239-246
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    • 2013
  • This study is aimed at understanding the color extendibility of color-field abstract through Mark Rothko's paintings. Color extendibility is a structure applied by Mark Rothko. He simplifies it and by pursuing autonomy and immediacy of the color itself, including surface color and the front of color-field, Rothko creates value through motions in his square paintings of non-fixed shapes. Chapter 2 revisits the meaning of color in abstract expressionism and explains the principle of color-field by applying the concept of ergon and parergon. In chapter 3, the principle, processes, methods, techniques of expression were studied as a basis to understand color extendibility and color-field abstract. In chapter 4, the works of Mark Rothko were analyzed based on his multiform paintings(1946-1948), number and untitled(1949-1957), and black paintings(1958-1970) in order to identify, in the final chapter, the features of color extendibility in Rothko's works. According to the above research, the thesis successfully concludes that the artist's reconstruction of reality and readjustment of transcendent reality are reproduced via color extendibility, the movement of color-field.

Estimating the Abundance and Fishing Mortality of Pacific Cod Gadus macrocephalus during the Spawning Season in Jinhae Bay, Korea, Using a Mark-Recapture Method (표지방류 조사를 통한 거제 외포 주변해역 대구(Gadus macrocephalus) 자원량과 어획사망률 추정)

  • Hwang, Kang Seok;Choi, Ilsu;Jung, Sukgeun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.45 no.5
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    • pp.499-506
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    • 2012
  • We estimated the population size and fishing mortality of Pacific cod Gadus macrocephalus during the spawning season in waters off Woipo, Geoje Island, Korea, using a mark-recapture method. We marked and released 51 cod>50 cm in total length; six were recaptured by local fishermen during the period from December 15 to 31, 2009. The estimated population size was ca. 180,000 and the fishing mortality of the exploitable cod was 26%. Although we could assume a closed population due to the short survey period, we evaluated the uncertainty in the estimates by applying bootstrap resampling because the sample size was small. The estimated 95% confidence interval was 94,000-568,000 for the population size and 8-49% for fishing mortality. Our study demonstrated that the application of mark-recapture methods and bootstrap resampling can be useful in stock assessment for fisheries management in Korea, but requires a larger sample size, spatially extensive coverage, and sophisticated mark-recapture models based on a refined sampling design for reliable stock assessment and biological reference points in sustainable cod management.