• Journal of Microbiology and Biotechnology
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• v.33 no.7
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• pp.941-948
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• 2023

Metabolites from medicinal plants continue to hold significant value in the exploration and advancement of novel pharmaceuticals. In the search for plants containing compounds with anti-inflammatory effects, we observed that the ethanol (EtOH) extract obtained from the aerial components of Gouania leptostachya DC. var. tonkinensis Pit. exhibited substantial suppression of nitric oxide (NO) in vitro. In a phytochemical study on an EtOH extract of G. leptostachya, 11 compounds were purified, including one unreported compound namely gouanioside A (1). Their chemical structures were unambiguously determined through the use of various spectroscopic techniques, such as 1 and 2D NMR, IR, and HR-ESI-MS, and by producing derivatives via chemical reactions. The EtOH extract, fractions, and a new compound exerted inflammatory effects by altering NO synthesis in murine RAW264.7 macrophage cells stimulated with lipopolysaccharide. The underlying inflammatory mechanism of the new compound 1 was also explored through various in vitro experiments. The results of this study indicate the potential usefulness of new compound 1 from G. leptostachya as a treatment for inflammatory diseases.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.4
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• pp.433-440
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• 2019

Offshore working environments such as ships, offshore oil and gas plants, and offshore wind turbines are isolated and directly exposed to rough seas, which pose high risks of safety accidents. Therefore, all workers in offshore plants should be able to cope with emergency situations and must be qualified according to relevant laws and regulations such as the International Convention on Standards of Training, Certification and Watchkeeping for Seafarers (STCW Convention) and Offshore Petroleum Industry Training Organization (OPITO) standards. In particular, marine workers should be able to perform cardiopulmonary resuscitation (CPR) in isolated locations or enclosed and confined spaces such as those in life-boats, life-rafts, rescue-boats, etc. Because the floor material is made of rubber, it may be difficult to perform chest compressions in life-rafts used to escape from emergency situations in ships or offshore plants. Chest compressions performed on life-rafts may reduce the accuracy of CPR and increase fatigue for those providing aid. To measure the accuracy and fatigue of those performing CPR in life-rafts, 15 experimenters with more than five years of experience as first aid instructors were exposed to different CPR environments in a marine safety training center equipped with an artificial wave generator. The results showed that the accuracy of CPR in the classroom was 99.6 %, but that in various life-raft environments was only 84 %. T-verification of the two sites confirmed the reduced accuracy of CPR performed on life-rafts. CPR on life-rafts should be performed in groups of two and with the use of automated chest compression devices.

• Environmental Engineering Research
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• v.21 no.3
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• pp.284-290
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• 2016

Life cycle assessment (LCA) methodology can be used to assess impacts on the environment that might be generated during treatment of wastewater and sludge treatment. In this work, LCA methodology was suggested to evaluate monthly environmental impact of wastewater treatment plants (WWTPs). Two field scale WWTPs, A2/O process and conventional activated sludge process (CAS), were selected as target plants and the operational data were collected from those plants. As the function units, the unit volume of treated wastewater of $1m^3$ and 1 kg T-N eq. removed were selected. The environmental effect of target WWTPs operation were assessed as impact categories such as global warming potential, eutrophication potential, and so on. From monthly profiles of each index, it was shown that the environmental impact of WWTPs has seasonal patterns influenced by the influent flow rate variation causing higher impacts in winter than summer. This is due to the fact that there were no significant increase in the electricity consumption and chemical usage during the summer while the treated volume of wastewater was increased.

• Journal of the Society of Naval Architects of Korea
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• v.47 no.4
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• pp.613-627
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• 2010

Ships and off-shore plants have very long lifecycles. Design data of ships and off-shore plants are used as master data in the subsequent phases after the design phase. Therefore, it is an important issue how to convert native design data generated from commercial shipbuilding CAD systems into neutral data with the use of international industrial data standards. International standard-based exchange of ship outfitting and off-shore plant data needs the construction of a library for specifications data of equipment and materials and the provision of external referencing mechanism for retrieving data stored in the library. This paper proposes an approach to construct a specifications data library with the use of ISO 15926 process plants. This library is used for providing specifications data through external referencing when translating ship outfitting data from TRIBON system into ISO 10303 STEP AP 227-formed data.

• Journal of Korean Society of Environmental Engineers
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• v.27 no.12
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• pp.1332-1339
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• 2005

The purpose of this study is to the distributive property of organic pollutants in effluents of domestic sewage treatment plants around Youngsan River using simultaneous analysis method of 310 chemicals. The numerous organic pollutants were detected in five sampling sites, and the major chemicals were pesticides, CH type chemicals such as benzenes and polycyclic compounds, ande CHO type chemicals such as phenols and phthalates. About 14 pesticides were detected in the effluent and most of them were found in summer. 1-Chlorobenzen and p-octylphenol were frequently detected in the concentration range of $0.52{\sim}0.61\;{\mu}g/L$ and $0.04{\sim}0.89\;{\mu}g/L$, respectively. Moreover, 18 kinds of endocrine disrupters include diethylphthalate were detected in effluents. From the results of this study, therefore, we confirmed that the pesticides, CH and CHO type chemicals in domestic effluents throughout Youngsan River are required specific regulation.

• Journal of the Korean Applied Science and Technology
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• v.35 no.4
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• pp.1487-1495
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• 2018

In this study, we investigated collagen production and hyaluronic acid production effects for wrinkle improvement test on 50 kinds of land plants and 10 kinds of marine plants native to Jeju Island as a part of developing customized cosmetic materials. Collagen and hyaluronic acid are recognized as major factors affecting skin aging. Cerastium holosteoides var. hallaisanense Mizushima extract ($100{\mu}g/mL$) produced more than 190% of collagen in the extracts of 50 kinds of land plants. Vicia angustifolia var. segetilis K. Koch. extract ($100{\mu}g/mL$) produced more than 160% of collagen. Ftsia japonica Decne. et Planch. extract ($100{\mu}g/mL$), Euonymus japonica Thunb. extract ($100{\mu}g/mL$), Suaeda malacosperma H.Hara extract ($100{\mu}g/mL$), Elaeagnus umbelellata Thunb. extract ($100{\mu}g/mL$), Sedum oryzifolium Makino extract ($100{\mu}g/mL$), Vicia unijuga A. Br. extract ($100{\mu}g/mL$), and Brassica juncea var. integrifolia Sinsk. extract ($100{\mu}g/mL$) showed more than 140% collagen production effect. Among the 10 species of marine plants, Sargassum macrocarpum C. Agardh extract ($50{\mu}g/mL$) produced more than 190% of collagen, and Carpopeltis angusta (Harvey) Okamura extract ($100{\mu}g/mL$), Codiumcoactum Okamura extract ($100{\mu}g/mL$), and Codium tenuifolium S. Shimada, T. Tadano & J. Tanaka extract ($100{\mu}g/mL$) showed more than 140% collagen production. Suaeda malacosperma H.Hara extract ($100{\mu}g/mL$) showed the effect of producing hyaluronic acid more than 140%, and Ftsia japonica Decne. et Planch. extract ($20{\mu}g/mL$) and Wistaria floribunda A.P. DC extract ($100{\mu}g/mL$) showed more than 130% hyalunonic acid production effect. Among the 10 species of marine plants, Peyssonnelia capensis Montagne extract ($100{\mu}g/mL$) was the most effective. Carpopeltis angusta (Harvey) Okamura extract ($100{\mu}g/mL$), Codiumcoactum Okamura extract ($100{\mu}g/mL$), and Codium tenuifolium S. Shimada, T. Tadano & J. Tanaka extract ($100{\mu}g/mL$) showed more than 120% hyalunonic acid production. Jeju resources, which have good collagen and hyaluronic acid production, showed the potential to be applied to solve the skin troubles of customized cosmetics in the future.

• Journal of Power System Engineering
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• v.22 no.1
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• pp.25-33
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• 2018

The safety of structure was evaluated by taking into consideration the complex marine environmental conditions of the Lattice boom crane, which is widely used in offshore plants due to less influence by wind. CFX analysis was carried out to take into account the influence of wind speed, and the result was applied as a boundary condition to perform static analysis according to the luffing angles of $28^{\circ}$, $61^{\circ}$, and $80^{\circ}$ in the on board and off board, respectively. In addition, the Lattice Boom Crane is large slender structure, and the possibility of buckling is interpreted under three conditions where the biggest stress occurs. All conditions satisfied the safety requirements of the Classification Regulations. Also, as a result of the buckling analysis, the load less than the critical load was applied so buckling does not occur.

• KSBB Journal
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• v.28 no.1
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• pp.36-41
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• 2013

Carotenoids are fat-soluble red-orange colored pigments found in plants and seafood-derived products, including algae, seaweeds, and fish muscle. In this study, we have demonstrated the molecular mechanism underlying the antioxidants and anti-inflammatory properties of ascidian tunic carotenoids using mouse macrophage cell line (RAW 264.7). Cell viability was not affected by treatment of carotenoids < 10 ${\mu}g/mL$. This treatment also showed negative inhibition on lipopolysaccharide (LPS)-stimulated nitric oxide (NO) and cyclooxygenase-2 (COX-2). The DPPH radical scavenging activity of carotenoids was 47.2% at 100 mg/mL. It also has a potential reducing power (1.025) comparable with ascorbic acid (1.584). The ascidian tunic carotenoids would make a candidate for the commercially interesting biologically active cosmetic pigments.

• Journal of the Korean Society of Industry Convergence
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• v.25 no.6_2
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• pp.1063-1069
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• 2022

In modern industry, vacuum has grown into an indispensable industrial field. The performance of the vacuum pump in the degasser system among mud treatment system facilities was verified by a numerical analysis method. The degasser system is an equipment for removing the gas contained in the mud, and it is a work process that requires a vacuum. This study analyzed the vacuum pump performance of the degasser used in drilling for resource development of onshore and offshore plants. The vacuum pump used in the degasser system was designed with a discharge rate of 0.099kg/s. The DM(Design Modeler) program of ansys workbench 17.2 was used to modify the model of the vacuum pump used in the degasser system. And for performance analysis, CFX, which is known to be suitable for rotating system analysis, was used. Finally the performance analysis results of the vacuum pump and the prototype performance test results were compared and analyzed.

• Korean Journal of Computational Design and Engineering
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• v.21 no.1
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• pp.78-89
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• 2016

When a plant owner requests plant 3D CAD models in the format that a shipbuilding company does not use, the shipyard manually re-models plant 3D CAD models according to the owner's requirement. Therefore, it is important to develop a technology to compare the re-modeled plant 3D CAD models with original ones and to quantitatively evaluate similarity between two models. In the previous study, we developed a graphic user interface (GUI)-based comparison system where a user evaluates similarity between original and re-modeled plant 3D CAD models for piping design at the level of unit. However, an offshore plant consists of thousands of units and thus a system which compares several plant 3D CAD models at unit-level without human intervention is necessary. For this, we developed a new batch model comparison system which automatically evaluates similarity of several unit-level plant 3D CAD models using an extensible markup language (XML) file storing file location and name data about a set of plant 3D CAD models. This paper suggests system configuration of a batch-mode-based comparison system and discusses its core functions. For the verification of the developed system, comparison experiments for offshore plant 3D piping CAD models using the system were performed. From the experiments, we confirmed that similarities for several plant 3D CAD models at unit-level were evaluated without human intervention.