• Journal of the Institute of Electronics Engineers of Korea SP
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• v.49 no.4
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• pp.10-15
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• 2012

In a color image, people and especially facial patterns are important and interesting visual objects. Thus, effective skin color reproduction is essential, as skin color is a key memory color in color application systems. Previous studies suggested skin color reproduction by mapping only to the center value of preferred skin region. However, it is not suitable to determine one preference color because preference color from the observer's preference test is not dominant. In this paper, skin color reproduction using multiple preferred skin colors for each race is proposed. The proposed method first defines multiple preferred skin colors for each race according to their luminance level. After that, skin region is detected in an image. The race is then selected by calculating distance between average chromaticity of detected region and that of each racial skin from a database to assign preferred skin color for each race. Next, each corresponding preferred skin color is determined for each selected race. Finally, input skin color is proportionally mapped toward preferred skin color according to the difference between the input skin color and the preferred skin color for a smoothly reproduced skin color. In the experimental results, the proposed method gives better color correction on the objective and subjective evaluation than the previous methods.

• Korean Journal of Digital Imaging in Medicine
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• v.9 no.2
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• pp.31-38
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• 2007

To evaluate the accuracy and extent in the localization of cerebral motor coutex activation using a gradient- echo echo planar imaging(GE-EPI) compared to spin-echo echo planar iimaging(SE-EPI) on 3T MR imaging. Functional MR imaging of cerebral motor cortex activation was examined in GE-EPI and SE-EPI in five healthy male volunteers. A right finger movement was accomplished with a paradigm of 6 task and rest, periods and the cross-correlation was used for a statistical mapping algorithm. We evaluated any sorts of differenced of the time seried and the signal intensity changes between the rest and task periods obtained with two technoques. The qualitative analysis was distributed with activation sites of large veins and small veins by using two techniques and was found that both the techniques were clinically uesful for delineating large veins and small veins in fMRL Signal intensity charge of the rest and activation periods provided simmilar activations in both methods(GE-EPI : 0.93$\pm$0.11, SE-EPI : 0.80$\pm$.015) but the signal intensity in GE-EPI(133.95$\pm$15.76) was larger than in SE-EPI(74.5$\pm$18.90). The average SNRs of EPI raw data were higher at SMA in SE-EPI(48.54$\pm$12.37) than GE-EPI(41.4$\pm$12.54) and at M1 in SE-EPI(43.24$\pm$11.77) than GE-EPI(38.27$\pm$6.53). The localization of activation voxels of the GE-EPI showed a larger vein but the SE-EPI generally showed small vein. Then the analysis results of the two techniques were used for a statistacal paired student t-test. SE-EPI was found clinically useful for localizing the cerebral moter cortex cativation on 3.0T, but showed a little different activation patterns comparad to GE-EPI. In conclusion, SE-EPI may be feasible and can detect true cortical activation from capillaries and GE-EPI can obtain the large veins in the motor cortex activation on 3T MR imaging.

• Journal of the Korean Geographical Society
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• v.43 no.1
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• pp.134-153
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• 2008

The main purpose of the research is to illustrate the value of the spatial statistical approach to residential differentiation by providing a framework for exploratory spatial data analysis (ESDA) using a local spatial separation measure. ESDA aims, by utilizing a variety of statistical and cartographic visualization techniques, at seeking to detect patterns, to formulate hypotheses, and to assess statistical models for spatial data. The research is driven by a realization that ESDA based on local statistics has a great potential for substantive research. The main results are as follows. First, a local spatial separation measure is correspondingly derived from its global counterpart. Second, a set of significance testing methods based on both total and conditional randomization assumptions is provided for the local measure. Third, two mapping techniques, a 'spatial separation scatterplot map' and a 'spatial separation anomaly map', are devised for ESDA utilizing the local measure and the related significance tests. Fourth, a case study of residential differentiation between the highly educated and the least educated in major Korean metropolitan cities shows that the proposed ESDA techniques are beneficial in identifying bivariate spatial clusters and spatial outliers.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6397-6403
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• 2014

Background: Aberrant promoter hypermethylation has been recognized in human breast carcinogenesis as a frequent molecular alteration associated with the loss of expression of a number of key regulatory genes and may serve as a biomarker. The E-cadherin gene (CDH1), mapping at chromosome 16q22, is an intercellular adhesion molecule in epithelial cells, which plays an important role in establishing and maintaining intercellular connections. The aim of our study was to assess the methylation pattern of CDH1 and to correlate it with the expression of E-cadherin, clinicopathological parameters and hormone receptor status in breast cancer patients of Kashmir. Materials and Methods: Methylation specific PCR (MSP) was used to determine the methylation status of CDH1 in 128 invasive ductal carcinomas (IDCs) paired with the corresponding normal tissue samples. Immunohistochemistry was used to study the expression of E-cadherin, ER and PR. Results: CDH1 hypermethylation was detected in 57.8% of cases and 14.8% of normal adjacent controls. Reduced levels of E-cadherin protein were observed in 71.9% of our samples. Loss of E-cadherin expression was significantly associated with the CDH1 promoter region methylation (p<0.05, OR=3.48, CI: 1.55-7.79). Hypermethylation of CDH1 was significantly associated with age at diagnosis (p=0.030), tumor size (p=0.008), tumor grade (p=0.024) and rate of node positivity or metastasis (p=0.043). Conclusions: Our preliminary findings suggest that abnormal CDH1 methylation occurs in high frequencies in infiltrating breast cancers associated with a decrease in E-cadherin expression. We found significant differences in tumor-related CDH1 gene methylation patterns relevant to tumor grade, tumor size, nodal involvement and age at diagnosis of breast tumors, which could be extended in future to provide diagnostic and prognostic information.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.10
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• pp.1565-1574
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• 2018

Objective: The aim of the present study was to identify genetic variants based on RNA-seq data, obtained via transcriptome sequencing of muscle tissue of pigs differing in muscle histological structure, and to verify the variants' effect on histological microstructure and production traits in a larger pig population. Methods: RNA-seq data was used to identify the panel of single nucleotide polymorphisms (SNPs) significantly related with percentage and diameter of each fiber type (I, IIA, IIB). Detected polymorphisms were mapped to quantitative trait loci (QTLs) regions. Next, the association study was performed on 944 animals representing five breeds (Landrace, Large White, Pietrain, Duroc, and native Puławska breed) in order to evaluate the relationship of selected SNPs and histological characteristics, meat quality and carcasses traits. Results: Mapping of detected genetic variants to QTL regions showed that chromosome 14 was the most overrepresented with the identification of four QTLs related to percentage of fiber types I and IIA. The association study performed on a 293 longissimus muscle samples confirmed a significant positive effect of transforming acidic coiled-coil-containing protein 2 (TACC2) polymorphisms on fiber diameter, while SNP within forkhead box O1 (FOXO1) locus was associated with decrease of diameter of fiber types IIA and IIB. Moreover, subsequent general linear model analysis showed significant relationship of FOXO1, delta 4-desaturase, sphingolipid 1 (DEGS1), and troponin T2 (TNNT2) genes with loin 'eye' area, FOXO1 with loin weight, as well as FOXO1 and TACC2 with lean meat percentage. Furthermore, the intramuscular fat content was positively associated (p<0.01) with occurrence of polymorphisms within DEGS1, TNNT2 genes and negatively with occurrence of TACC2 polymorphism. Conclusion: This study's results indicate that the SNP calling analysis based on RNA-seq data can be used to search candidate genes and establish the genetic basis of phenotypic traits. The presented results can be used for future studies evaluating the use of selected SNPs as genetic markers related to muscle histological profile and production traits in pig breeding.

• Journal of the Korean Arthroscopy Society
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• v.9 no.1
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• pp.40-45
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• 2005

Purpose: This study is to evaluate the clinical findings of media] meniscus root tear, pull-out repair technique and it's short term results. Materials and Methods: From September 2003 to August 2004, 23 cases of total 27 medial meniscus root tears were treated by pull-out repair technique. Mean age was 60.2 years old. The pull-out technique was divided into 2 groups In group 1(14/23 cases), anterolateral portal was used and in group 2(9/23 cases), anterolateral and posteromedial portals were used for bed preparation. Concomitant cartilage lesions were documented as ICRS mapping system. The clinical outcomes were evaluated according to Lysholm Knee Score. Results: The postoperative Lysholm Knee Score was 77.1(range; $58{\sim}97$) in group 1 and 81.4(range; $72{\sim}94$) (p>0.05). The failure rate was 3 of 14 cases(21.4%) in group 1 and 1 of 9 cases(11.1%) in group 2. Twenty of 22 cases(90.9%) showed cartilage lesions in weight bearing portion of medial femoral condyle which were 8 grade III and 5 grade IV according to the Outerbridge classification. Conclusion: Pull-out repair seems to be a useful treatment of the medial meniscus root tear for preservation of circumferential hoop tension of meniscus.

• Journal of the Korean Society of Costume
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• v.20
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• pp.151-167
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• 1993

The purpose of this study is to systematize the theory of the Fashion Marketing and merchandi-sing system as well as the strategy for the Mar-keting based on the related variable. Furthermore, this study deals with development of the mark-eting strategy to the relation between consumers and industry. The content conclusion on the research can be outlined as follows : 1. In order to inverstigate how the life-style of consumers affects their sense of fashion, awa-reness of brand, and decision making process of purchase, the life-style of women consumers is classified into 15 types. (1) Acording to the different life-style types, and important difference is found in the consum-ers' sense of clothes, a unique image of outfit and its own favorite image of womanliness. (2) The consumer's awareness of a particular brand has a reasonable relationship with their brand preference and possession of the brands. (3) Their is an important discrimination acco-rding to the life-style types in their brand awar-eness and preference and possesion of brands. (4) The consumers of each life-style type show noticeable difference in the decision making pro-cess of purchase including he motive of purchase, the source of information, the cause of purchase intention, price, the frequency of purchase and the degree of satisfaction of purchased goods. 2. The merchandising system and the market positioning among the fashion industry are compared and analyzed in the following terms ; (1-1) For the purpose of establishing the target market strategy, the industry uses unreasenalbe methods to analyze the life-style of the target customers and the real customers(36%) and the aging phenomenon of brands is remarkable : as much as 37% of brands show over 5 years-old age gap. (1-2) The price setting process depends highly on the cost-plus approach. (1-3) In color planning, too many colors are used in every season(the average number is 22.3) and the investigation of the consumers' favorite color is neglected. (1-4) The manufacturers of successful brands are much likely to employ the textile designer and allow them to develop the various fabrication. (1-5) The regular rate of sales in each season is extremely low(56.04%) : the rate of the succ-essful brands is relatively high at 65%, but that of the unsuccessful as low as 51%. (1-6) 47% of brands reveal the designer-orie-nted fashion merchandising system. The successful brands, on the other hand, show a high rate of merchandiser oriented system. (2) Since the brand positioning is highly cen-tered on each brand image, styles and target age, the new data are presented in this study for the new market development. (3) To set up the target market, the mapping of images between the differentiated market and the consumers is suggersted according to the market positioning of industry and 15 types of the life-styles of consumers.

• Investigative Magnetic Resonance Imaging
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• v.6 no.2
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• pp.137-146
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• 2002

Purpose : This paper introduces an improved classification approach which adopts a deterministic relaxation method and an agglomerative clustering technique for the classification of MRI using neural network. The proposed approach can solve the problems of convergency to local optima and computational burden caused by a large number of input patterns when a neural network is used for image classification. Materials and methods : Application of Hopfield neural network has been solving various optimization problems. However, major problem of mapping an image classification problem into a neural network is that network is opt to converge to local optima and its convergency toward the global solution with a standard stochastic relaxation spends much time. Therefore, to avoid local solutions and to achieve fast convergency toward a global optimization, we adopt MFA to a Hopfield network during the classification. MFA replaces the stochastic nature of simulated annealing method with a set of deterministic update rules that act on the average value of the variable. By minimizing averages, it is possible to converge to an equilibrium state considerably faster than standard simulated annealing method. Moreover, the proposed agglomerative clustering algorithm which determines the underlying clusters of the image provides initial input values of Hopfield neural network. Results : The proposed approach which uses agglomerative clustering and deterministic relaxation approach resolves the problem of local optimization and achieves fast convergency toward a global optimization when a neural network is used for MRI classification. Conclusion : In this paper, we introduce a new paradigm to classify MRI using clustering analysis and deterministic relaxation for neural network to improve the classification results.

• The KIPS Transactions:PartD
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• v.13D no.4 s.107
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• pp.549-556
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• 2006

In this paper, we propose a system for generating skeleton programs for directly transforming an XML document to another document, whose structure is defined in the target DTD with GUI environment. With the generated code, the users can easily update or insert their own codes into the program so that they can convert the document as the way that they want and can be connected with other classes or library files. Since most of the currently available code generation systems or methods for transforming XML documents use XSLT or XQuery, it is very difficult or impossible for users to manipulate the source code for further updates or refinements. As the generated code in this paper reveals the code along the XPaths of the target DTD, the result code is quite readable. The code generating procedure is simple; once the user maps the related elements represented as trees in the GUI interface, the source document is transformed into the target document and its corresponding Java source program is generated, where DTD is given or extracted from XML documents automatically by parsing it. The mapping is classified 1:1, 1:N, and N:1, according to the structure and semantics of elements of the DTD. The functions for changing the structure of elements designated by the user are amalgamated into the metadata interface. A real world example of transforming articles written in XML file into a bibliographical XML document is shown with the transformed result and its code.

• Journal of KIISE:Software and Applications
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• v.33 no.9
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• pp.787-801
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• 2006

Ontology merging describes the process of integrating two ontologies into a new ontology. How this is done best is a subject of ongoing research in the Semantic Web, Data Integration, Knowledge Management System, and other ontology-related application systems. Earlier research on ontology merging, however, has studied for developing effective ontology matching approaches but missed analyzing and solving methods of problems of merging two ontologies given correspondences between them. In this paper, we propose a specific ontology merging process and a generic operator, T-MERGE, for integrating two source ontologies into a new ontology. Also, we define a taxonomy of merging conflicts which is derived from differing representations between input ontologies and a method for detecting and resolving them. Our T-MERGE operator encapsulates the process of detection and resolution of conflicts and merging two entities based on given correspondences between them. We define a data structure, MergeLog, for logging the execution of T-MERGE operator. MergeLog is used to inform detailed results of execution of merging to users or recover errors. For our experiments, we used oriental philosophy ontologies, western philosophy ontologies, Yahoo western philosophy dictionary, and Naver philosophy dictionary as input ontologies. Our experiments show that the automatic merging module compared with manual merging by a expert has advantages in terms of time and effort.